• 제목/요약/키워드: 선량 감소

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Bioassay in BALB/c mice exposed to low dose rate radiation (저선량율 방사선 조사한 BALB/c 마우스에서의 영향평가)

  • Kim, Sung-Dae;Gong, Eun-Ji;Bae, Min-Ji;Yang, Kwang-Mo;Kim, Joong-Sun
    • Journal of Radiation Protection and Research
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    • v.37 no.3
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    • pp.159-166
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    • 2012
  • The present study was performed to investigate the toxicity of low-dose-rate irradiation in BALB/c mice. Twenty mice of each sex were randomly assigned to four groups of five mice each and were exposed to 0 (sham), 0.02, 0.2, or 2 Gy, equivalents to low-dose-rate irradiation to 3.49 $mGy{\cdot}h^{-1}$. Urine, blood, and blood biochemistry were analyzed, and organ weight was measured. The low-dose-rate irradiation did not induce any toxicologically significant changes in mortality, clinical signs, body weight, food and water consumption, urinalysis, and serum biochemistry. However, the weights of reproductive organs including the testis, ovary, and uterus decreased in a dose-dependent manner. Irradiation at 2 Gy significantly decreased the testis, ovary, and uterus weights, but did not change the weights of other organs. There were no adverse effects on hematology in any irradiated group and only the number of neutrophils increased dose dependently. The low-dose-rate irradiation exposure did not cause adverse effects in mice at dose levels of 2 Gy or less, but the reproductive systems of male and female mice showed toxic effects.

Characteristics of Dose Distribution at Junctional Area Using the Divergency Cutout Block in the Abutted Field of Photon and Electron Beams (광자선과 전자선의 인접조사에서 선속 퍼짐현상이 고려된 전자선 차폐물을 이용한 접합 조사면의 선량분포 특성)

  • Im, In-Chul;Lee, Jae-Seung
    • Journal of Radiation Protection and Research
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    • v.36 no.3
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    • pp.168-173
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    • 2011
  • This study investigated characteristics of dose distribution at junction field of X-ray and electron beams according to the method for fabricating the insert block on the electron cone. Insert block were fabricated to the divergency cutout block and the straight cutout block. For the 6 MV X-ray and 10 MeV nominal energy of electron beam, we was adjacent to the light field of X-ray and electron beam at a surface of matrix chamber and measured to beam profile of abutted field in the 0, 1, 2, 3 cm measurement depth. As a result, characteristics of dose distribution at junction field, straight block was existent that over dose area exceed the give dose more than 5% and under dose area with a rapid change in dose distribution. However, divergency block had remarkably decreased the over dose area caused by the lateral scattering effects of decrease, and being existed uniformity dose distribution in the junction field. Therefore, divergency block were the benefits of radiation dose delivery, in order to applied the clinical, measurement of electron beams according to the fabrication method of the block should be considered carefully.

A high energy radiation evaluation test of the 74AC04 Hex Inverter (고준위 감마방사선 환경에서의 원격계측을 통한 74AC04 의 내방사선 영향평가 및 분석)

  • Oh, Seung-Chan;Lee, Hyun-Jin;Lee, Nam-Ho;Lee, Heung-Ho
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.1788_1789
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    • 2009
  • 본 논문에서는 핵폭발과 같은 고준위방사선환경에서의 전자부품소자의 피해평가분석을 통하여 군용전자장비의 내방사선화를 하기 위한 기반기술의 확립을 위한 연구의 일환으로 74AC04(Inverter) IC에 대한 고준위감마선조사시험을 통하여 Co-60 Gamma-ray 선원을 사용하여 총 400Krad[si] 누적 선량에 대한 74AC04 소자의 동작특성 및 전기적 파라메터의 변화분석을 진행하였다. 시험평가 방법 및 절차는 MIL-STD-883G 1019.7[1] 및 ESA/SCC Basic Specification No.22900[2] 절차를 기준으로 하여 동일 lot에 대한 5개의 샘플을 이용하여 동작특성에 영향을 미치는 주요한 전기 적파라메터인 정지소비전류, 입력누설전류, VIL(Maximum Low Level Input Voltage)에 대한 변화추이를 분석하였다. 이번 조사시험을 통하여 입력게이트에서의 누적선량에 따른 TID(Total Ionizing Dose) 효과로 인한 VIL의 감소 추이를 확인 할 수 있었으며 총 누적선량 160Krad 이상에서의 VIL은 허용기준치이하로 감소하였고 정지소비전류의 경우 누적선량에 따른 점진적 증가 현상과 200Krad부근에서의 설계스펙허용치를 초과하는 결과를 확인하였다.

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자기장을 이용한 미래형 방사선치료에 관한 연구

  • 오영기;정동혁;김기환;신교철;김정기;김성규;지영훈;김진기
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.55-55
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    • 2003
  • 본 연구에서는 최근 미래형 방사선치료 기술로서 관심이 집중되고 있는 자기장을 이용한 선량분포 변환 및 집중기술에 대하여 물리적 배경과 임상적 응용 가능성을 논의하였다. 먼저 물리적 이론으로부터 물질속 자기장에서 전자의 운동을 고찰하였으며 다음에는 몬테칼로 계산을 이용하여 임상에 이용되는 고에너지 광자와 전자선에 대하여 선량분포를 계산하였다. 물에 인가된 수 Tesla 자기장에 대하여 전자들의 기본 경로는 자기장과 수직방향으로 편향을 받으며 원궤도를 취하였으며 궤도반경은 에너지의 손실에 따라 점차 줄어드는 것으로 나타났다. 가로방향의 인가 자기장에 대한 몬테칼로 계산결과 광자 및 전자선에 대하여 자기장 인접영역에서 급격한 선량증가 현상이 발생하였는데 10 MV 광자선의 경우에 3T와 5T에서 각각 약 40%와 80%의 선량증가를 확인하였으며 전자선의 경우에도 유사한 결과가 나타남을 확인하였다. 또한 자기장 종단영역에서는 흡수선량의 급격한 감소가 발생하는 것으로 나타났는데, 본 연구에서는 이러한 특성들을 이용하여 종양에 방사선량을 집중시키고 주변 정상조직을 효과적으로 보호할 수 있는 미래형 최적화 방사선치료의 모델들을 제시하였다. 본 연구의 주요결과들은 최근 관련 실험들로부터 점차 명백해지고 있으며, 자기장을 병행한 방사선치료 기술의 국내 기반기술 확보에 기여할 것으로 기대한다.

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Evaluation of the Apron Effectiveness during Handling Radiopharmaceuticals in PET/CT Work Environment (PET/CT 업무 환경에서 선원 취급 시 Apron의 실효성 평가)

  • Cho, Yong-In;Ye, Soo-Young;Kim, Jung-Hoon
    • Journal of radiological science and technology
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    • v.38 no.3
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    • pp.237-244
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    • 2015
  • Health professionals in nuclear medicine were known that they get high radiation exposure. To reduce radiation exposure, using shielding materials is needed. In this study, we analyzed the shielding effect about apron during 18F-FDG treatment by using simulation based on Monte Carlo techniques and actual measurement. As a result, absorbed dose distribution of organ varies with handling position of the source. Dose reduction ratio by lead thickness of apron tended to decease, when handling position of the source come close to organ and away from radiation source for simulation. In the case of actual measurement with the dosimetry device, It showed that mean spatial dose distribution was different due to characteristics of dosimetry device. However, spatial dose rate was exponentially reduced according to distance with increasing lead content.

The Effects of Magnetic Field on TLD Glow Curve (자기장이 열형광선량계의 글로우 곡선에 미치는 영향)

  • Je, Jaeyong;Kang, Eunbo
    • Journal of the Korean Society of Radiology
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    • v.7 no.6
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    • pp.415-418
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    • 2013
  • Thermoluminescent dosimeter utilizes the fact that when irradiated specimen is heated up, some part of the absorbed energy is emitted from the specimen as light with longer wavelength. This research aims at analyzing the glow curves of four TLD-100 exposed to a magnetic field and those of other four TLD-100 not exposed to one by treating them with heat and irradiating them, which are commonly used as thermoluminescent dosimeter, in the same condition. As the result of the experiment, regarding the electrons captured by irradiation, some of the electrons of lower traps were combined with positive holes of valence band through the exposure to a magnetic field, and the peak size decreased by 48%. The reduction in the size of the lower traps caused the TLD-100 exposed to a magnetic field to display a low level of dose. In addition, low traps estimated activation energies are 1.6 eV and 1.5 eV.

Radiation Effects on Pyricularia oryzae Cav. Causing Rice Blast Disease Organism (도열병균의 방사선감수성에 관한 연구)

  • Kwon Shin Han;Oh Jeung Haing;Kim Ho Won
    • Korean journal of applied entomology
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    • v.13 no.4 s.21
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    • pp.245-249
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    • 1974
  • In order to establish a dose limits for subsequent induced mutation research itl Pyricularia oryzae, X-ray sensitivity of the conidia and the vegetative hypae of the fungus, race N-1, was investigated. Conidia of the fungus irradiated with X-rays reduced significantly in spore germination inversely with radiation doses. A severe suppression of conidia germination in about $80\%$ was found at the dose of 120kR, and the rests of the conidia produce very short and lysed germ tubes. A stimulated effect was observed in the elongation of hyphae from the conidia of 10 kR irradiation at initial stage of the growth. The radiosensitivity of hyphae was exremely higher than that of conidia with the increase of radiation doses. It was also recognized that the frequency of X-ray induced mutation in pathogenicity was directly proportional to radiation doses.

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A Monitoring Ability of the High-Performance Color CCD Camera under High Dose-Rate Gamma Ray Irradiation Environments (고 선량율 감마선 조사 환경에서의 고성능 칼라 CCD 카메라의 관측성능)

  • Cho, JaiWan;Choi, Young Soo;Seo, Yong Chil;Jeong, KyungMin
    • Proceedings of the Korea Information Processing Society Conference
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    • 2014.04a
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    • pp.811-814
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    • 2014
  • 일본 후쿠시마 제일 원자력발전소의 대지진/쓰나미에 이은 원자로 건물 수소폭발 사고의 수습 과정에서 사용후 핵연료 저장조에 보관되어 있는 핵연료의 안전문제가 대두되었다. 사용후 핵연료의 잔열 성분을 냉각시키고, 그리고 사용후 핵연료가 방출하는 고선량 방사선을 차폐시키기 위해서 일정 깊이 이상의 수조에 사용후 핵연료를 저장한다. 사용후 핵연료 저장조에 냉각수 공급이 중단되면, 사용후 핵연료의 고유 잔열에 의해 수조의 물이 증발하여 수위가 감소하게 된다. 계속해서 냉각수 공급이 되지 않으면, 사용후 핵연료의 잔열은 증가하게 되고, 수조의 물은 비등하여 증발은 가속화 된다. 사용후 핵연료 저장조의 수위가 고갈되면 고선량의 감마선이 방출된다. 수조의 수위가 정상적일 경우 사용후 핵연료 저장조의 공기중 감마선 선량율은 0.15mSv/h 이다. 수조의 수위가 사용후 핵연료 상부 꼭대기를 기준으로 2m, 1m, 및 0m (핵연료 노출) 로 감소하게 되면, 사용후 핵연료 저장조의 공기중 감마선 선량율은 500mSv/h, 50Sv/h, 및 5kSv/h 로, 급격히 증가한다. 본 논문에서는 사용후 핵연료 저장조 감시카메라의 관측 성능을 평가하기 위해, 고성능 칼라 CCD 카메라에 대해서 1 kGy/h 의 고선량율로 감마선 조사실험을 수행하였다. 이에 대한 실험결과를 기술한다.

Radioresistance of Acorus calamus to Gamma Ray Irradiation

  • Lee, Ja-Hyun;Kang, Si-Yong;Lee, Geung-Joo;Lee, Seong-Gene;Kim, Sun-Kook;Han, Tae-Ho
    • FLOWER RESEARCH JOURNAL
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    • v.19 no.2
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    • pp.119-125
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    • 2011
  • Acorus calamus is an indigenous hydrophyte used as phytoremediation and water purification as well as medicinal herb. Irradiation of gamma ray was performed to investigate the effect on radioresistance of A. calamus on in vitro. Various doses (20-500 Gy) of gamma rays were irradiated to in vitro plantlets. The effect of irradiation was studied on survival rate, shoot formation and growth rate. The survival and multiplication rate was remarkably decreased with the increase of radiation dose. The growth of plantlets was significantly increased in comparison to the control at low doses. The hermetic effect of radiation was appeared in A. calamus. It was significantly decreased or interrupted above 250 Gy. The mean 50% lethal dose ($LD_{50}$) was extremely high as 240 Gy. We conclude that A. calamus had remarkably high radioresistance compared with other plant species.

A Comparison Analysis of CT Effective Dose and Image Quality according to Abdominal Diameter (복부직경에 따른 CT유효선량 및 화질변화 비교 분석)

  • Yoon, Joon;Kim, Hyeonju
    • Journal of the Korean Society of Radiology
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    • v.12 no.7
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    • pp.821-826
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    • 2018
  • This study was performed randomly from all the patients who visited the University Hospital in Gyeonggi-do from January 1, 2018 to June 30, 2018 for the abdominal CT scan. We divided the patients into three groups and evaluated the extent of effective dose and image quality according to the area of the abdominal CT image. As a result, the effective dose was 7.34 mSv in the average area group, 8.39 mSv in the average area and 5.89 mSv in the average area. For the analysis of image quality, ROI was plotted in the same three regions according to the abdominal area. As a result, CT values were significantly different in the abdominal area classified into 3 groups (p <0.05). The results of this study can be used as a basic data for the development of a protocol that can be applied in actual clinical practice. It is thought that it can help to reduce the image quality and the radiation dose.