• Title/Summary/Keyword: 생체적합도

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Design and Implementation of Bio-data Monitering System Based on ISO/IEEE 11073 DIM/REST for IoT Healthcare Service (IoT 헬스케어 서비스를 위한 ISO/IEEE 11073 DIM/REST 기반 생체정보 모니터링 시스템 설계 및 구현)

  • Choi, Ju-Hyun;Chun, Seung-Man;Jang, Dong-Hyun;Park, Jong-Tae
    • Journal of the Institute of Electronics and Information Engineers
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    • v.52 no.3
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    • pp.3-12
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    • 2015
  • Recently, various studies have been attempted to provide a biological information monitoring service through integrating with the web service. The medical information transmission standard ISO/IEEE 11073 PHD defines the optimized exchange protocol ISO/IEEE 11073-20601 based on the No-IP to exchange the biometric information between the ISO/IEEE 11073 agent and the manager. It's system structure based on the No-IP using ISO/IEEE 11073-20601 is not suitable for providing a remote biological information monitoring services. That is because it is difficult to provide to control and manage the biological information measurement devices, which have installed IP protocol stack at the remote. Furthermore, ACSE and CMDISE in ISO/IEEE 11073-20601 are not suitable to provide U-healthcare services based on IoT because they are complicated and difficult to implement it caused by the structural complexity. In order to solve the problems, in this paper, we propose the biological information monitoring architecture based on ISO/IEEE 11073 DIM/REST of IoT environment to provide the biological information monitoring service based on IoT. To do this, we designed biological information monitoring system architecture based on IoT and the message exchange protocol of ISO/IEEE 11073 DIM/REST between the ISO/IEEE 11073 agent and the ISO/IEEE 11073 manager. In order to verify the realistic possibility of the proposed system architecture, we developed the service prototype.

A study of changes on the physical properties of silk fibroin biological membrane according to the dissolving conditions (실크피브로인 용해조건에 따른 생체막의 물성 변화)

  • Jo, You-Young;Kweon, HaeYong;Lee, Kwang-Gill;Lee, Heui-Sam
    • Journal of Sericultural and Entomological Science
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    • v.50 no.2
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    • pp.71-75
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    • 2012
  • Silk is a natural polymer that has the advantages of the biocompatibility, excellent mechanical strength, low immune rejection, and molding facility. But silk does not dissolve easily in water or general solvent. To investigate the characteristics of silk biological membranes according to dissolving condition of silk fibroin, we made the silk biological membranes using silk fibroin solutions with different amount and dissolving time of silk. The characterizations of the silk biological membranes such as morphology, structure, and mechanical strength were observed. Although each biological membrane has the same fibroin content, there was a significant difference in the thickness and transparency. But there was no significant change in the molecular weight of the silk fibroin solutions and morphology of silk biological membranes. We were established the manufacturing condition for silk fibroin biological membrane. So we expect that the conditions will help in the development of medical supplies in the future.

Relative Biocompatibility Evaluation of Anodized Titanium Specimens in vivo and in vitro (In vivo와 in vitro 에서 양극산화 처리한 타이타늄 시편의 상대적인 생체적합성 평가)

  • Lee Yu-Mi;Lee Eun-Jung;Yeom Dong-Sun;Kim Do-Soon;Yee Sung-Tae;Kim Byung-Il;Cho Hyun-Wook
    • Journal of Life Science
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    • v.16 no.2 s.75
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    • pp.302-309
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    • 2006
  • To evaluate the biocompatibility of untreated and anodized titanium specimens, the specimens were implanted in the subcutaneous tissue of the abdominal region of female mice for two weeks. The reaction of connective tissue to specimens was histologically studied. The implants were encapsulated by fibrous connective. tissue consisting of fibroblast, fibrocyte and other cellss including neutroophil, macrophage and giant multinucleated cell. some newly formed blood vessels were located in the fibrous capsule surrounding the implant. Giant multinucleated cells were observed at the fibrous capsule adjacent to the implant. Kind of cell types and the thickness of fibrous capsules were examined quantitatively. Most of cell types located in the fibrous capsule were fibroblast and fibrocyte. The average thickness of fibrous capsules for the anodized specimens was much thinner than that of the untreated titanium specimen. Biocompatibility of titanium specimens were also studied by using cell culture method. The number of MG-63 cells was significantly increased on the anodized titanium specimens in vitro experiment. Our observations suggest that anodized titanium specimens are more effective for the improvement of biocompatibility in vivo and in vitro.

Biocompatibility Evaluation of Bent-Type Left Ventricular Assist Device During Long-Term Animal Experiment and Emergent Situation (장기 동물 실험 및 응급상황에서의 곡관형 좌심실보조장치의 생체적합성 평가)

  • Kang, Seong Min;Her, Keun;Choi, Seong Wok
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.38 no.9
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    • pp.739-745
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    • 2014
  • Although medication is given to heart disease patients, conventional medication alone is not sufficient to treat heart disease. However, it has been reported that left ventricular assist device (LVAD) transplantation is an effective bridge to heart transplantation by assisting cardiac function. This study used long-term animal testing and emergency situations with a bovine model (Holstein) and canine model (Labrador-retriever) to evaluate the biocompatibility of LibraHeart-I (LH-1), which is a bent-tube type of LVAD that was developed in a previous study. In the long-term animal testing with the bovine model, the subjects survived for 49 days with no irregularities observed in their complete blood cell counts or the vital sign tests that were carried out during the test period. In short-term animal testing with the canine model, it was observed that blood did not remain inside the LH-I even without power support from an external drive source. In this study, the biocompatibility of the LH-I that was developed in a previous study was verified by the ejection performance during long-term animal testing and emergency situations.

견 피브로인/카이토산 복합체 섬유의 제조 및 특성화 (I)

  • 박근후;류동일;초상연;신윤숙;박원호
    • Proceedings of the Korean Fiber Society Conference
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    • 1998.10a
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    • pp.45-48
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    • 1998
  • 카이토산(chitosan)은 항미생물성, 무독성, 인체적합성 및 양이온성 등의 특성을 지니며 항균, 방취, 보습, 생체적합성 및 생분해성 등의 다양한 기능을 나타내고 있는데, 이를 바탕으로 카이토산을 단독 또는 다른 천연섬유재료와 복합화시키는 연구가 행해지고 있다. 본 연구에서 선택한 카이토산과 복합체를 형성할 수 있는 성분인 견 피브로인(silk fibroin)은 17 종의 아미노산으로 이루어진 단백질로서 의류용 및 의료용 재료로서 이용되고 있는 고급섬유재료이다. (중략)

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The Design of Biosignal Acquisition Board Using USB (USB를 이용한 생체 신호 계측용 데이터 수집보드의 설계)

  • Hwang, Eon-Ju;Park, Min-Je;Kim, Dong-Yeon;Yoo, Jae-Ha;Kim, Soo-Chan
    • Proceedings of the KIEE Conference
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    • 2008.04a
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    • pp.135-136
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    • 2008
  • 본 연구에서는 USB(Universal Serial Bus)통신과 전기적 절연을 이용하여 생체신호계측이 가능한 USB 데이터 수집(DAQ, Data acquisition)보드를 설계 및 구현한 것이다. 대부분의 데이터 수집보드는 전기적 절연이 되어 있지 않기 때문에 의용계측에 있어서 적합하지 않다. 보드를 평가하기 위해 설계한 USB DAQ 보드와 PC를 사용하여 사인파와 램프신호 그리고 생체신호중 하나인 ECG 신호를 측정하였다. 제안한 USB 데이터 수집보드는 AD변환부, 전기적 절연부, 전송부, 디지털 입 출력부 그리고 DC-DC변환기(DC DC Convertor)로 구성되었고, 최대 1KHz의 샘플링 주파수와 12비트 분해능과 8채널의 성능을 가진다.

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