• Title/Summary/Keyword: 생체간이식

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Donor Complication in Living Donor Liver Transplantation (생체간이식에 관한 공여자 합병증)

  • Yang, Jae Do;Yu, Hee Chul
    • Korean Journal of Transplantation
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    • v.31 no.4
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    • pp.177-181
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    • 2017
  • Living donor liver transplantation (LDLT) has become an inevitable procedure due a shortage of deceased donors under the influence of religious and native cultures. The most important concern in LDLT is donor safety. This study reviewed the safety of LDLT donors from reported studies of morbidity and mortality. Many studies have reported mortality and morbidity rates ranging from 0% to 33% for healthy liver donors. Use of laparoscopic surgery on LDLT donors has advantages of reduced blood loss, lower postoperative morbidity and shorter hospital stay relative to conventional open surgery. There is a consensus that remnant liver volume (RLV), degree of steatosis, and donor age are the most important factors influencing donor safety. In LDLT, donor hepatectomy can be performed successfully with minimal and easily controlled complications. However, a large-scale prospective cohort study is needed to better understand the risk factors and accurately determine the complication rates for LDLT.

Auto-Segmentation Algorithm For Liver-Vessel From Abdominal MDCT Image Using Morphological Filtering (Morphological Filtering을 이용한 복부 MDCT 영상의 간혈관 자동 추출 알고리즘)

  • Park, Chun-Ja;Ryu, Gang-Min;Park, Jong-Won
    • Proceedings of the Korea Information Processing Society Conference
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    • 2005.05a
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    • pp.819-822
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    • 2005
  • 본 연구는 MDCT 영상을 이용하여 인체의 장기인 간을 추출하고 그 간 내부의 혈관을 추출하는 알고리즘을 제안하였다. 간에는 2개의 주요혈관이 있는데 생체 간 이식 수술시 필수적인 간의 절개 비율 및 간 내의 혈관 모습들을 제공하여 의료진에게 수술 전 혈관 형태에 대한 정확히 정보를 파악하도록 함으로써 혈관의 손상을 최대한으로 줄일 수 있도록 하여 수술 성공률을 높이는데 중요한 역할을 할 수 있다. 간을 이식 할 때 기증자와 수혜자가 동시에 생존하기 위해서는 기증자의 간으 크기가 중요하며 둘다 생존하기 위해서는 기증자는 자신의 간의 35% 이상을 남겨야 하며 수혜자 또한 생존을 위해 자신의 간의 40% 이상에 해당하는 간을 이식 받아야 하는데 간 이식에 있어서 절단 부분을 결정하는데 중요한 중간 정맥을 찾아내어 보여 줌으로써 중간 정맥을 중심으로 3가닥의 굵은 혈관과 주변혈관의 손상을 최소화하고 비율을 잘 맞추어 절단 할 수 있도록 수술하는데 도움을 줄 수 있다. 각 혈관은 원형성과 다양한 각도를 갖는 막대형의 형태를 가지고 있다는 특징을 이용해 morphological filtering을 통해 추출한 후 조합하여 재구성을 하여 혈관의 모습으로 생성해 낼 수 있었다.

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Development of Transcutaneous Energy Transmission System for Medical Instrument (의료용 무선 에너지 전달 장치의 개발)

  • 안재목;이동준
    • Journal of Biomedical Engineering Research
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    • v.16 no.4
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    • pp.447-456
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    • 1995
  • As a part of electro-mechanical totally implantable artificial heart (TIAH) program, a transcut- aneous energy transmission system has been developed. By mutual magnetic induction between the first coil on the skin and the subcutaneously implanted second coil, the system transfers elctrical power through the skin. This research aimed at minimizing the size of the implanted part as well as maximizing the transfer efficiency. Using class I amplifier, we achieved above 75% power transfer efficiency at average 40W power transfer level which is required for normal TIAH operation. In vivo performance of the developed system and bio-compatibility of the material used in Implanted parts were evaluated through animal experiments.

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Liver Cut Method Using 4 Points for Hepatic Volumerty at MDCT Image (MDCT 영상에서 간 체적 계산을 위한 4 점 이용 간 분할 방법)

  • Seo, Jeong-Joo;Cho, Baik-Hwan;Park, Jong-Won
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.47 no.1
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    • pp.17-24
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    • 2010
  • This paper proposed the method to separate a liver into left and right liver lobes for exact volumetry of the river graft at abdominal MDCT(Multi-Detector Computed Tomography) image before living donor liver transplantation. On the image of segmented liver, 4 points(the middle point of Inferior Vena Cava, a point of Middle Hepatic Vein, a point of Portal Vein, a middle point of gallbladder fossa) are selected. A liver is separated into left and right liver lobes on the basis of the 4 points. The volume and ratio of the river graft are estimated. The volume estimated using 4 points and the manual volume that radiologist processed and estimated are compared with the weight measured during surgery to support proof of the exact volumetry. After selection the 4 points, the time involved in separation a liver into left and right river lobe and volumetry of them is measured for confirmation that the algorithm can be used on real time during surgery. This study progressed to ensure donor's and recipient's safe who will undergo the liver transplantation.

Liver Splitting Using 2 Points for Liver Graft Volumetry (간 이식편의 체적 예측을 위한 2점 이용 간 분리)

  • Seo, Jeong-Joo;Park, Jong-Won
    • The KIPS Transactions:PartB
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    • v.19B no.2
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    • pp.123-126
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    • 2012
  • This paper proposed a method to separate a liver into left and right liver lobes for simple and exact volumetry of the river graft at abdominal MDCT(Multi-Detector Computed Tomography) image before the living donor liver transplantation. A medical team can evaluate an accurate river graft with minimized interaction between the team and a system using this algorithm for ensuring donor's and recipient's safe. On the image of segmented liver, 2 points(PMHV: a point in Middle Hepatic Vein and PPV: a point at the beginning of right branch of Portal Vein) are selected to separate a liver into left and right liver lobes. Middle hepatic vein is automatically segmented using PMHV, and the cutting line is decided on the basis of segmented Middle Hepatic Vein. A liver is separated on connecting the cutting line and PPV. The volume and ratio of the river graft are estimated. The volume estimated using 2 points are compared with a manual volume that diagnostic radiologist processed and estimated and the weight measured during surgery to support proof of exact volume. The mean ${\pm}$ standard deviation of the differences between the actual weights and the estimated volumes was $162.38cm^3{\pm}124.39$ in the case of manual segmentation and $107.69cm^3{\pm}97.24$ in the case of 2 points method. The correlation coefficient between the actual weight and the manually estimated volume is 0.79, and the correlation coefficient between the actual weight and the volume estimated using 2 points is 0.87. After selection the 2 points, the time involved in separation a liver into left and right river lobe and volumetry of them is measured for confirmation that the algorithm can be used on real time during surgery. The mean ${\pm}$ standard deviation of the process time is $57.28sec{\pm}32.81$ per 1 data set ($149.17pages{\pm}55.92$).

Design of Implantable Wireless Sensor Node to Monitor the Livestock Body Temperature (가축의 실시간 체온 측정을 위한 이식형 무선 센서 노드 설계)

  • Kim, Hyun-Joong;Yang, Hyun-Ho
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.10a
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    • pp.585-588
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    • 2009
  • Wireless Sensor Network (WSN) is consisted of lots of tiny sensor nodes with limited processing power and computing resources. Thus, the most critical and fundamental element of WSN technology is sensor node, which gathers environmental information and transmits it to the user application systems. Due to the technological advancement, sensor nodes are become smaller and more intelligent, hence, expand their application area. Specifically, implantable wireless sensor node technology, to monitor and treat disease by implanting tiny sensor nodes into human body or livestock, shows further directions of WSN. In this paper, we have designed an implantable wireless sensor node to monitor livestock body temperature in real time. We also discussed on the additional considerations to implement real time bio-monitoring systems.

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젖소 생체로부터 초음파기기와 간이 난자채취기를 이용한 미성숙 난포란의 채란효율 연구

  • 박성재;류일선;이동원;연성흠;서국현;허태영;백광수;안병석;김일화
    • Proceedings of the KSAR Conference
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    • 2001.10a
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    • pp.63-64
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    • 2001
  • 유전적으로 우수한 능력을 보유하고 있는 소의 과배란처리로 수정란을 생산·이식하여 송아지를 생산하는 연구가 지속적으로 이루어지고 있으며, 생체로부터 연속적으로 미성숙 난자를 채란하여 수정란을 생산하는 연구가 근래에 와서 많이 보고되고 있다. 본 연구는 정상적으로 번식이 불가능한 젖소를 이용하여 생체 내 미성숙난자의 장기간 채란 시에 초음파기기와 간이 난자채취기의 효율성을 검토하고, 연속적인 반복 채란의 효율, 채란 난포란의 등급, 반복채란에 의한 장애우 발생 등에 대한 영향을 조사하여 고능력 소에서 체외수정란 안정적 생산에 활용 가능성을 검토하고자 실시하였다. (중략)

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