• Title/Summary/Keyword: 생존 분포

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A comparison of the statistical methods for testing the equality of crossing survival functions (교차하는 두 생존함수의 동일성 검정법에 관한 비교연구)

  • Lee, Youn Ju;Lee, Jae Won
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.3
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    • pp.569-580
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    • 2015
  • Log-rank is widely used for testing equality of two survival functions, and this method is efficient only under the proportional hazard assumption. However, crossing survival functions are common in practice. Therefore, many approaches have been suggested to test equality of them. This study considered several methods; Renyi type test, modified Kolmogorov-Smirnov and Cramer-von Mises test, and weighted Log-rank test, which can be applied when the survival functions cross, and simulated power of those methods. Based on the simulation results, we provide the useful information to choose a suitable approach in a given situation.

A comparison of the statistical methods for testing the equality of two survival distributions (두 생존분포의 동일성 검정에 관한 비교연구)

  • 정미남;이재원
    • The Korean Journal of Applied Statistics
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    • v.11 no.1
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    • pp.113-127
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    • 1998
  • There have been a great deal of interests in comparing two survival distributins in clinical trials. This paper compares some well-known statistical methods for testing the equality of two survival distributions. Simulation studies also provide some insights into the properties of these test statistics across several types of survival distributions and degrees of censorship.

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A Comparison of Survival Distributions with Unequal Censoring Distributions (이질적인 중도절단분포 하에서 생존분포의 동일성 검정법 비교연구)

  • Song, Sujeong;Lee, Jae Won
    • The Korean Journal of Applied Statistics
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    • v.27 no.1
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    • pp.1-11
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    • 2014
  • The Weighted Logrank test and its special case, Logrank test are widely used to compare survival distributions; however, these methods are inappropriate when the sample size is small or censoring distributions are not equal since they use test statistics from approximate distributions. A permutation test can be an alternative for small sample cases; however, this should be used only when censoring distributions are equal. To handle cases with small sample size and unequal censoring distributions, the permutation-imputation method was developed to compare two survival distributions. In this paper, approximate method, permutation method and permutation-imputation method were compared using a Logrank test and Prentice-Wilcoxon test for three or more survival distributions comparison.

중도절단된 생존함수의 신뢰구간 비교연구

  • Lee, Gyeong-Hwa;Lee, Jae-Won
    • Proceedings of the Korean Statistical Society Conference
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    • 2005.05a
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    • pp.251-255
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    • 2005
  • 중도절단된 자료와 표본수가 적은 자료를 가지는 생존분석에서 생존율을 추정하거나 두 집단의 생존율을 비교할 때 정규분포 근사를 가정한 신뢰구간을 이용하는 데는 많은 어려움이 생긴다. 생존함수의 신뢰구간에 대한 중도절단을, 표본의 크기에 따른 다양한 상황의 모의실험을 통하여 Kaplan-Meier, Nelson, 적률 추정량 그리고 cox model의 ${\beta}$을 가지고 붓스트랩을 이용한 신뢰구간과 비모수 신뢰구간, 우도비 신뢰구간의 실제 포함 확률을 비교해보고자 한다.

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Cell Viability and Fatty Acids Composition of Zymomonas mobilis grown at different Concentrations of Ethanol (Zymomonas mobilis 균체의 지방산 분포와 균의 생존성에 미치는 ethanol 농도의 영향)

  • 권석흠;이계준
    • Korean Journal of Microbiology
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    • v.25 no.1
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    • pp.80-85
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    • 1987
  • The aim of the present studies was to analyze the physiological background of ethanol inhibition in Zumomonas mobilis. The experiments were carried out with a number of continuous culture to give steady state concentration of ethanol. The domposition of fatty acids in the cells obtained from various conditions was analyzed and cell viability was also estimated. As results, it was found that vaccenic acid was the mafor fatty acid in the cell of Z. mobilis and the concentration was changed apparently to increase as increasing the concentration of ethanol produced from substrate utilization. Finally it was observed also that cell viability was decreased remarkably at the elevated ethanol concentration. Those changes might play important roles in the ethanol fermentation to give more complex phenomena observed at high concentration of ethanol.

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Beta Processes and Survival Analysis (베타과정과 베이지안 생존분석)

  • Kim, Yongdai;Chae, Minwoo
    • The Korean Journal of Applied Statistics
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    • v.27 no.6
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    • pp.891-907
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    • 2014
  • This article is concerned with one of the most important prior distributions for Bayesian analysis of survival and event history data, called Beta processes, proposed in Hjort (1990). We review the current state of the art of beta processes and their application to survival analysis. Relevant methodological and practical areas of research that we touch on relate to constructions, posterior distributions, large-sample properties, Bayesian computations, and mixtures of Beta processes.

Sample Size Determination Comparing Survival Distributions in the Stratified Clinical Trials (층화된 임상시험에서 생존분포의 비교를 위한 표본수의 결정)

  • 김선우;박미라;이재원
    • The Korean Journal of Applied Statistics
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    • v.12 no.1
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    • pp.175-190
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    • 1999
  • 생존시간을 비교하기 위한 임상시험에서는 생존기간과 관련된 위험인자들을 고려한 층화된 연구설계가 종종 요구된다. 이 경우 필요한 표본수가 결정은 층이 없는 경우에 비하여 다양한 연구상황과 복잡한 표본수의 산출 절차를 수반한다. 본 논문에서는 층이 있는 경우 생존시간을 비교할 때 필요한 표본수를 결정하는 방법들을 실례와 함께 설명하고, 연구자가 주어진 상황하에서 적절한 방법을 선택하는데 도움이 될 수 있도록, 다양한 상황을 설정하여 이에 대한 표본수를 비교하였다.

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The Distribution Pattern of Eggs and Larval Survival Rate of Phyllocnistis citrella (Lepidoptera: Gracillaridae) on the Leaves of Shoots in a Citrus Orchard in Jeju (제주 감귤원에서 귤굴나방 알의 신초 잎 위치별 분포와 유충의 생존률)

  • Hyun, Seung Young;Kim, Su Bin;Kim, Dong-Soon
    • Korean journal of applied entomology
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    • v.58 no.3
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    • pp.175-182
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    • 2019
  • The citrus leafminer, Phyllocnistis citrella (Lepidoptera: Gracillaridae), is an important pest that decreases the productivity of citrus trees by attacking citrus leaves, and especially it causes a severe damage during the young growth stage. In this study, we investigated the distribution of eggs on the leaves of shoots according to the position and the survival rate of this pest in the field condition. The occurrence patterns of P. citrella eggs in citrus orchards were largely affected by the occurrence of shoots. Even if the adults were still being attracted in the pheromone traps, the eggs were not observed on leaves when the growth of shoots was stopped. The density of P. citrella eggs in the citrus shoots peaked at the fifth or sixth leaf from the terminal leaf, and over 90% of the eggs were found in the first to eighth leaves as a whole. In 2015 and 2016, the average survival rate of larvae surviving to pupa was 1.4%, and the rate of survival to adults was 0.2%, indicating that most of them died. Furthermore, we have discussed the management strategy of P. citrella considering the distribution of eggs and the larval survival rate in the citrus shoots.

Locational Characteristics of Survived and Closed Coffee Shops by Spatial Cluster Type (커피전문점 생존 및 폐업 분포의 군집 유형별 생멸 특성)

  • Park, Sohyun;Eo, Jeongmin;Lee, Keumsook
    • Journal of the Economic Geographical Society of Korea
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    • v.23 no.4
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    • pp.408-424
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    • 2020
  • This study attempts to analyze the spatial clustering of survived and closed coffee shops based on the land price and land use for each coffee shop location. The locational characteristics of survived and closed coffee shops for each cluster type are identified through various locational properties such as transport factors (physical accessibility), shop properties (franchise information, newly open/closed business experience), and spatial density (kernel density estimation). To this end, we categorize the clusters of survived and closed coffee shops into three types (general locational distribution type, commercialization type of residential area and location type of commercial center), and then analyze their locational characteristics. As the result, we found that the locations of newly open and closed coffee shops show different distribution characteristics, even though they are classified into the same type due to the double sidedness of new open and closed locations. The results of this study can be provided as basic data for planning the location of coffee shop as well as regional commercial district.

Bivariate reliability models with multiple dynamic competing risks (다중 동적 Competing Risks 모형을 갖는 이변량 신뢰성 모형에 관한 연구)

  • Kim, Juyoung;Cha, Ji Hwan
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.3
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    • pp.711-724
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    • 2016
  • Under variable complex operating environment, various factors can affect the lifetimes of systems. In this research, we study bivariate reliability models having multiple dynamic competing risks. As competing risks, in addition to the natural failure, we consider the increased stress caused by the failure of one component, external shocks, and the level of stress of the working environment at the same time. Considering two reliability models which take into account all of these competing risks, we derive bivariate life distributions. Furthermore, we compare these two models and also compare the distributions of maximum and minimum statistics in the two models.