• Journal of the Korean BIBLIA Society for library and Information Science
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• v.12 no.2
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• pp.71-84
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• 2001

The purpose of this study is to provide the methods of preservation for paper, microfilm, digital media. First of all, for acidic papers produced in 19~20 centuries, this study evaluates and analyses deterioration and factors causing deterioration. For book, also, environmental condition for preservation, and a preservation mechanism through acid-free procedure were suggested. Second for microfilm, it emphasized physical and chemical properties, oxidised substance during developing film, materials related to preservation. Third, for digital storages, storage conditions and needs, such as life-cycle and capacity were introduced.

• Proceedings of the Safety Management and Science Conference
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• 2013.11a
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• pp.185-197
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• 2013

우리나라는 선진국 진입을 눈앞에 두고 있다. 하지만 세계시장 진입의 장벽과 고객신뢰 및 자원의 한계로 인해 어려움을 겪고 있다. 이러한 한계점을 극복하기 위해서는 신인성경영시스템을 기반으로 한 기업 평가가 이루어져야 한다. 즉 제품의 기능과 성능 등의 적합성(Conformity)특성 중심의 기업생존을 위한 기본전략 평가에서 이제는 기업노력 대비 고객만족과 경영성과를 높일 수 있는 수명과 내구성, 안전성 등의 시간 종속성(Dependability) 중심의 평가가 시급하다. 본 논문에서는 국가 품질상에 대한 구조를 분석해보고 국가 경쟁력 분석을 통한 문제점을 도출하여 신인성경영시스템을 기반으로 한 기업 평가 방안의 타당성과 구체적 실행방안을 제시하고자 한다.

• 월간산업보건
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• s.296
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• pp.52-56
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• 2012

산업안전보건의 규제에 대해서는 상반된 의견이 있다. 일부 사람들은 작업장의 규제가 기업의 경쟁력을 약화시키고 일자리를 없앤다고 하고, 다른 사람들은 규제가 사업주나 근로자에게 최소의 비용으로 작업장을 안전하게 지킨다고 주장한다. 저자들은 산업안전 감독이 산재율과 다른 결과에 어떠한 영향을 미치는지를 보기 위해 통상적인 현장 감독을 분석했다. 무작위로 선정되어 감독을 실시한 409개의 캘리포니아 소재 기업과 감독대상이지만 감독을 실시하지 않은 동수의 기업을 대조군으로 선정하여 분석했다. 대조군에 비해 감독을 받은 기업은 재해율이 9.4%(95% 신뢰구간: -0.177~-0.021) 감소했고, 사고관련 비용은 26%(95% 신뢰 구간: -0.513~-0.083)가 감소했다. 저자들은 이러한 개선이 고용, 판매, 신뢰지수 및 기업의 생존의 희생 댓가로 얻어졌다는 증거는 찾지 못했다.

• 한국벤처창업학회:학술대회논문집
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• 2022.04a
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• pp.45-49
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• 2022

코로나-19는 4차 산업혁명은 산업 전 분야의 디지털 전환을 가속화할 것으로 전망된다. 이러한 시장환경에서 유연하게 변화하거나 새롭게 창출하지 못하면 빠르게 도태되어 실패에 이를 수 있다. 이러한 분위기에서 창업기업의 생존과 성장할 수 있도록 창업자와 창업기업 구성원들의 디지털역량을 높이기 위한 다양한 노력들이 지속되고 있다. 본 연구의 목적 역시 창업기업 CEO의 기업가 정신이 창업성과와 어떠한 상관관계를 가지고 있는가를 조사하고 시장의 변화 대응하기 위한 디지털역량이 매개역할을 하는지에 대해 분석 하는데 있다. 본 연구에서는 창업기업 CEP의 기업가정신이 기업의 창업성과에 미치는 영향에 관한 연구를 디지털역량의 매개효과를 중심으로 진행하고자 한다. 따라서 본 연구에서는 CEO의 기업가정신이 창업기업의 디지털역량을 증진하고, 디지털역량이 창업성과에 미칠 것이라는 인과적 경로를 검증하고자 한다. 4차 산업혁명에 따른 변화에 따라 창업가를 대상으로 기업가정신, 디지털역량, 창업성과를 분석함으로 써, 창업기업의 경쟁력 확보와 성과창출을 위한 시사점을 도출하고자 한다.

• Tuberculosis and Respiratory Diseases
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• v.62 no.3
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• pp.203-210
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• 2007

Background: The incidence of adenocarcinoma of the lung has been increasing worldwide, and it has been generally been accepted to be relatively unrelated to smoking with a female preponderance. The aim of this study was to examine the gender-related pathological and survival differences in patients with an adenocarcinoma of the lung. Material and Method: A retrospective review of the clinical information of patients diagnosed with an adenocarcinoma of the lung at Kosin Medical Center from January 1999 to September 2005 was performed. The patient's demographics (age, gender), smoking history, stage, serum tumor marker, pathology classification, EGFR mutation, K-ras mutation, treatment methods, and survival time were analyzed. Result: Of the 438 patients, 179 (40.9%) were female. The median age at the diagnosis was 58 years for females and 59 years for males. However, 25.8% of women and only 17.7% of men were under 50 years of age (p=0.02). The distribution of the disease stage was similar in both men and women. The bronchioloalveolar carcinoma component was diagnosed more often in women (11.2%) than in men (5.0%). The overall survival rate was higher in women than in men (p=0.01), and women had a superior therapeutic response to a combined treatment of surgery and chemotherapy. Conclusion: This study showed significant genders differences in terms of the smoking history, bronchioloalveolar carcinoma component, overall survival, and survival after combined treatment of surgery and chemotherapy. Therefore, gender differences should be considered when diagnosing and treating adenocarcinomas of the lung.

• International Area Studies Review
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• v.15 no.1
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• pp.367-389
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• 2011

This paper examines what factors contribute to the entry of foreign investors to Chinese commercial banks from 1996 to 2008. Empirical results show that using survival analysis, size, liquidity ratio and non-interest incomes are important to foreign investors. This indicates that as Chinese banking system opened, foreign investors invest in bigger but financially weak banks. For Joint-Stock commercial banks, foreign investors invest in banks whose asset qualities and non-interest incomes are low. But for City commercial banks, foreign investors invest in banks that are big but have low liquidity ratios. This results indicate that because City commercial banks operate in only one city, foreign investors require minimum bank size to operate in that city.

• Journal of Digital Convergence
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• v.20 no.5
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• pp.423-432
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• 2022

Due to the development of treatments due to COVID-19, the Firm-value of the pharmaceutical industry has increased. However, the development of treatments has been delayed, and the development of overseas markets has become difficult due to COVID-19. Therefore, this study aims to present an efficient management plan for each firm by analyzing the management efficiency of these firms. As for the research method, DEA analysis was conducted for the pharmaceutical industry. Through this method, we propose values of input variables that inefficient companies can benchmark. As a result of the analysis, there was no significant difference in management efficiency before and after COVID-19, but it was confirmed that the management efficiency of certain Firm decreased. Through this study, it is possible to judge a Firm's survival competitiveness and management strategy, and furthermore, a plan to continuously grow and enhance competitiveness was suggested.

• Journal of Life Science
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• v.25 no.3
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• pp.263-268
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• 2015

Coelomocytes are specialized cells that continually and nonspecifically scavenge fluid from the body cavity through endocytosis in Caenorhabditis elegans. Our previous study revealed that coelmocytes were specifically required for dietary-restriction-induced longevity in C. elegans. In the present study, we examined the effect of coelomocyte ablation on the response to environmental stressors and reproduction in C. elegans. Coelomocytes were ablated using diphtheria toxin specifically expressed in coelomocytes. After exposing worms to 20 J/cm²/min of ultraviolet irradiation in vivo, the survival of the worms was monitored daily. To examine their response to heat stress, their survival after 10 h of 35℃ heat shock was measured. Oxidative stress was induced using paraquat, and the susceptibility to oxidative stress was compared between wild-type control and coelomocyte-ablated worms. The total number of progeny produced was counted, and the time-course distribution of the progeny was determined. The worms with ablated coelomocytes showed reduced resistance to ultraviolet irradiation, but the ablation of coelomocytes had no effect on their response to heat or oxidative stress. The number of progeny produced during the gravid period was significantly decreased in the coelomocyte-ablated worms. These findings suggest that coelomocytes specifically modulate the response to ultraviolet irradiation and are required for normal reproduction in C. elegans. The findings could contribute to understanding of the mechanisms underlying dietary-restriction-induced longevity.

• Radiation Oncology Journal
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• v.26 no.1
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• pp.17-23
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• 2008

Purpose: The best treatment for advanced esophageal cancer is chemoradiotherapy followed by surgery. In spite of the advance of multimodality therapy, most patients with esophageal cancer are treated with radiation therapy alone. This study reports the outcome of the use of conventional external beam radiotherapy alone for the treatment of esophageal cancer. Materials and Methods: Between January 1998 and December 2005, 30 patients with squamous cell carcinoma of the esophagus were treated with external beam radiotherapy using a total dose exceeding 40 Gy. Radiotherapy was delivered with a total dose of 44-60 Gy(median dose, 57.2 Gy) over $36{\sim}115$ days(median time, 45 days). Thirteen patients(43.3%) had a history of disorders such as diabetes, hypertension, tuberculosis, lye stricture, asthma, cerebral infarct, and cancers. Four patients metachronously had double primary cancers. The most common location of a tumor was the mid-thoracic portion of the esophagus(56.7%). Tumor lengths ranged from 2 cm to 11 cm, with a median length of 6 cm. For AJCC staging, stage III was the most common (63.3%). Five patients had metastases at diagnosis. Results: The median overall survival was 8.3 months. The survival rates at 1-year and 2-years were 33.3% and 18.7%, respectively. The complete response rate $1{\sim}3$ months after radiotherapy was 20%(6/30) and the partial response rate was 70%(21/30). Sixteen patients(53.3%) had an improved symptom of dysphagia. Significant prognostic factors were age, tumor length, stage, degree of dysphagia at the time of diagnosis and tumor response. Cox regression analysis revealed the aim of treatment, clinical tumor response and tumor length as independent prognostic factors for overall survival. Twenty-eight patients had local failure and another four patients had metastases. Three patients were detected with double primary cancers in this analysis. A complication of esophageal stricture was observed in three patients(10%), and radiation pneumonitis occurred in two patients(6.7%). Conclusion: The prognosis of esophageal cancer remains poor, in spite of advances in radiotherapy techniques. Radiotherapy is one of the main treatment modalities for the relief of dysphagia and treatment related complications are minimal. It is expected that the addition of chemotherapy or another systemic modality to radiotherapy will improve tumor control and increase the survival rate in advanced esophageal cancer.

• Korean Journal of Food Science and Technology
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• v.54 no.2
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• pp.203-208
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• 2022

Gluten is an insoluble protein present in cereals such as wheat. Gluten consumed through food is not digested and accumulates in the body; this has been linked to digestive discomfort, irritation, and various digestive disorders, including intestinal inflammation. In this study, the Lactobacillus paracasei strain GLU70, which exhibits a glutendegrading ability, was isolated from salted seafood. At a pH of 3.0, GLU70 showed a survival rate of approximately 84%, and at 0.3% oxgall, it showed a survival rate of approximately 53%. When the culture supernatant collected after 12 h of incubation was added to flour dough, approximately 50% gluten degradation was observed. Moreover, among several probiotic isolates exhibiting proteolytic activity selected to assess the gluten-degrading ability, GLU70 showed superior results regardless of the dough fermentation temperature. Although further research is required, GLU70 is expected to be of value in manufacturing gluten-reduced products and the food industry as an ingredient or additive.