• The Korean Journal of Pesticide Science
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• v.17 no.3
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• pp.155-161
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• 2013

The residue patterns of clothianidin and thiacloprid, insecticides registered in the ginseng, were investigated to predict pre-harvest residues limits (PHRL). Pesticides were treated under Korea GAP (Good Agricultural Practices) with the recommended dose (single dose) and twice of recommended dose (double dose). Samples were collected 11 times over 42 days (each 0, 2, 5, 8, 12, 16, 20, 24, 28, 33, 42 days after treatment). Residues of clothinidin and thiacloprid were analyzed by UPLC/TQD. Biological half-life of clothinidin in single dose and double dose were 14.6 days and 10.2 days and that of thiacloprid were also 9.7 days and 11.2 days, respectively. The PHRL of ginseng on 10 days before harvest was 0.3 mg/kg in clothianidin and 0.18 mg/kg in thiacloprid.

• Journal of Energy Engineering
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• v.15 no.2 s.46
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• pp.118-126
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• 2006

This publication provides an overview of the state-of-the-art and perspective of biological $H_2$ production from water and/or organic substances. The biological $H_2$ production processes, being explored in fundamental and applied researches, are direct and indirect biophotolysis from water, photo-fermentation, dark anaerobic fermentation and in vitro $H_2$ production. The development of biological $H_2$ production technology, as an energy carrier, started at the late 1940's in the lab-scale. Now it has a high priority in the world, especially USA, Japan, EU and Korea.

• Proceedings of the Korean Society for Bio-Environment Control Conference
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• 1996.10a
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• pp.76-80
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• 1996

공정육묘는 기후의 영향을 쉽게 받는 자연광하에서 대부분의 생산이 이루어지기 때문에 계획적인 묘생산이 어렵게 된다. 향후 식물공장(Plant factory) 또는 폐쇄생태계생명유지시스템(Controlled ecological life support system, CELSS)과 같이 폐쇄도가 높은 식물생산 시스템에서는 식물종묘 생산의 대부분이 인공광을 이용한 조건에서 이루어질 것으로 예상된다. (중략)

• Bulletin of Food Technology
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• v.7 no.2
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• pp.13-15
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• 1994

유산균은 발효유, 치즈, 발효 sausage 및 채소의 생산에 널리 이용되고 있다. 과거 15~6년간 이들 유산균에 대한 경제적 중요성은 매우 증가하였으며 이에 따라 유산균의 유전학과 plasmidbiology를 이해함으로써 이들 균에 대한 분자 생물학적 육종에 대한 많은 연구가 진행되어 왔다. 유산균에서 잘 기능을 하는 cloning vector들이 많이 개발되었으며 transduction, conjugation, transformation, electroporation 등의 외부 유전자를 전달하는 방법으로 보다 개발된 유산균이 육종되어 왔다. 이 총설은 산업적으로 유용가치가 높은 유산균의 육종에 관한 최신동향 및 앞으로의 전망 등에 관하여 논의하고자 한다.

• Proceedings of the Korean Information Science Society Conference
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• 2004.04b
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• pp.244-246
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• 2004

마이크로어레이 칩 실험을 통하여 대량으로 생산되는 유전자 발현 데이터는 여러 가지 클러스터링 방법을 적용하여 분석할 수 있으며, 생성된 클러스터들 또한 여러 가지 방법으로 해석 할 수 있다. 본 논문에서는 기존의 클러스터링 방법들을 응용한 seed클러스터링 방법을 제안하고 생물학적 온톨로지인 Gene Ontology를 기반으로 클러스터를 해석한다. 본 논문에서는 효과적인 유전자 발현 데이터 클러스터링 방법과 생물학적 지식을 바탕으로 클러스터를 해석, 평가하는 방법을 보여 준다.

• Journal of Pharmaceutical Investigation
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• v.30 no.4
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• pp.309-318
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• 2000

우리나라에서는 1989년 1월 1일 이후 허가된 신약과 동일한 의약품을 제조하거나, 제제개선을 통하여 흡수율을 향상시키는 경우 등에 있어서 생물학적 동등성 시험을 실시하여 두 제제간의 생체이용률을 비교하도록 규정되어 있다. 다른 나라에서도 신약과 동일한 의약품을 허가 받고자 할 경우나 대체조제를 위한 복제의약품의 생산 시 생물학적 동등성 시험자료를 제출하도록 하고 있으며, 이에 따른 생물학적 동등성 시험 기준을 운영하고 있다. 최근 각국에서는 국제적 조화를 이룬 기준을 마련하고자 하는 추세이다. 현재 우리나라에서는 의약분업 실시에 따라 생물학적 동등성 시험의 중요성이 부각되고 있으며 국제적인 수준에 맞추어 관련 기준을 개정해야할 필요성이 대두되고 있다. 캐나다에서는 1992년에 처음 생물학적 동등성 시험 기준을 공표하여 평가하고 있다. 본 논문에서는 캐나다의 생물학적 동등성 시험 기준을 소개하여 현행 규정과 비교 검토함으로써 생물학적 동등성 시험 기준을 보다 과학적이고 윤리적이며 합리적인 규정으로 개정하기 위한 자료로 활용하고자 한다.

• The Korean Journal of Mycology
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• v.42 no.4
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• pp.333-340
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• 2014

The aim of this study was to isolate a potential multifunctional biocontrol agent from bacteria for control of multiple plant diseases as an alternative to fungicides. A total of 201 strains were isolated from soil undamaged by repeated cultivation in Sunchang and their ability to produce antibiotics, siderophores and extracellular enzymes such as protease, cellulase and amylase was investigated. Selected strain SCS3 produced cellulose, protease and amylase. This strain also produced siderophores and showed excellent antifungal activity against various phytopathogens. SCS3 was identified as Bacillus subtilis using 16S rRNA sequencing, and named Bacillus subtilis SCS3. Finally, physiological and biochemical characteristics of B. subtilis SCS3 were examined. From the results, B. subtilis SCS3 was found to be a useful multifunctional biocontrol agent against various phytopathogens.

• Journal of Korean Society of Environmental Engineers
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• v.28 no.4
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• pp.362-367
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• 2006

Waste activated sludge(WAS) collected from domestic wastewater treatment plant is biomass that contains large quantities of organic matter. However, relevant literature show that the bio-hydrogen yield using WAS was too low. In this study, the effect of pretreatment of WAS on hydrogen yield was investigated. Pretreatment includes acid and alkali treatments, grinding, heating, ozone and ultrasound methods. After pretreatment organic matters of WAS were solubilized and soluble chemical oxygen demand(SCOD) was increased by 14.6 times. Batch experiments were conducted to investigate the effects of pre-treatment methods and buffer solution, hydrogen partial pressure, and sodium ion on hydrogen production from WAS by using heated anaerobic mixed cultures. Experimental results showed that addition of buffer solution, efficient pre-treatment method with alkali solution, and gas sparging condition markedly increased the hydrogen yield to 0.52 mmol $H_2/g$-DS.

• KSBB Journal
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• v.25 no.2
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• pp.199-204
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• 2010

We generated the feasibility of DNA separation in free-solution using genetically engineered repetitive polypeptides as drag-tags. Two different-sized repetitive polypeptides were designed, expressed in E. coli, and purified. They were conjugated to a fluorescently labeled DNA (100 base), and the electrophoretic mobilities of these conjugate molecules were analyzed on a microchip. The results of these studies indicate that genetically engineered repetitive polypeptide is a prominent candidate for rapid and high-throughput genetic mutation detection, such as SNP analysis.

• Korean Journal of Food Science and Technology
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• v.23 no.2
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• pp.161-166
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• 1991

For the production of useful products from microorganism, a bacterial strain producing the biopolymer was isolated from soil. The bacteriological characteristics of the strain were examined and some chemical properties of the biopolymer produced were investigated. The bacterial strain was identified as an alkali-tolerant Bacillus sp. The results of chemical composition, various color reactions and I.R. spectrum revealed that the biopolymer contained high protein content, low amino sugar and no uronic acid. However, the biopolymer was precipitated by treating with cetylpiridinium chloride and was found to be acidic.