• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.475-475
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• 2023

직경 5 mm 이하의 미세플라스틱은 인류 활동에 의해 생산되어 하수처리장 처리수, 우수토구, 도로 분진 등 다양한 경로를 통해 하천에 유입되고 있다. 하천에 유입된 미세플라스틱은 하천흐름을 따라 하류로 이동하여 해양환경에까지 이른다. 미세플라스틱은 수체를 따라 이동할 뿐 아니라 수생생물에 의해 섭식되기도 하여 인체 위해성이 우려되는 상황이다. 특히 서울과 경기도의 주요 상수원인 팔당호는 북한강, 남한강, 경안천이 유입되어 형성되기 때문에 미세플라스틱의 유입에 따른 이송-분산 거동 평가가 중요한 영역이다. 본 연구에서는 준3차원 입자추적기법을 이용한 미세플라스틱 거동해석 모형, MPT-Q3D를 개발하였으며 팔당호 내 미세플라스틱의 거동 특성을 분석하였다. MPT-Q3D 모형은 2차원 흐름해석모형과 연계한 입자의 준3차원 거동해석을 위해 step-by-step computation method를 적용하였으며, 전단류에 의한 입자의 수평거동과 난류확산에 및 침강속도에 의한 연직거동 두 단계 계산과정에 따라 입자의 거동을 해석했다. 전단류는 2차원 흐름해석결과로부터 유속의 연직분포식을 적용하여 생성하였으며, 생성된 전단류에 의해 각 연직층 별 유속이 계산되고 𝚫t 이후 입자의 종, 횡 방향 이동거리를 계산한다. 또한 난류확산에 의한 무작위적 거동 계산을 위해 Gaussian 분포를 따른 난수 생성을 통해 무작위적 거동을 계산했다. 각 연직층에 위치한 미세플라스틱 입자의 종, 횡 방향 거동을 계산한 후 입자의 연직거동을 계산한다. 입자의 연직 위치는 난류확산과 침강속도에 따라 계산되며 침강속도는 미세플라스틱의 밀도 및 직경에 따라 결정된다. 현장 샘플링 결과에 따라 팔당호로 유입되는 미세플라스틱은 폴리스틸렌(PS), 폴리에틸렌(PE), 폴리에스테르(Polyester)가 있으므로, 세 종류의 미세플라스틱을 동시에 주입하여 팔당호 내 거동을 분석했다. 남한강, 북한강, 경안천의 유량 차이로 인해 팔당호로 유입되는 미세플라스틱은 대체로 남한강과 북한강의 흐름특성에 영향을 받았다. 경안천의 경우 유량이 낮아 팔당호로 유입되지 못하고 좌안을 따라 하류로 이동됐다. 남한강과 북한강에서 유입된 미세플라스틱은 주로 팔당호 내 소내섬을 거쳐 팔당댐 쪽으로 이동했다. 또한 팔당댐 인근에서는 PP, PE, Polyester 순으로 많은 양이 유입되는 결과가 나타났다.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.12 no.2
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• pp.112-120
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• 2007

This paper reviews the use of parasites as 'biological tags' for studying stock analysis of salmonid fishes. Numerous definitions of stock concepts exist, but most of them essentially define a group of fish as having similar biological characteristics and being self-reproducing as stocks. It is important to manage fish stocks for human consumption and sustainable production and especially for salmonid fishes. Because these fry are considered as each country's property, it is necessary to identify and discriminate each fish stock in the open sea. Methods of separating fish stocks are very diverse. Artificial tags, parasites, otoliths scales and genetic characters have been used for stock analysis and each method has advantages and disadvantages. Of these parasites can be good biological tags because they are applied by nature at no cost. Parasites can be infected with susceptible host fishes when they enter into certain areas. Then if they move to the outside and are caught researchers can infer that the fish had been in the endemic area for a period of time during their life. Hence the host fish can be considered as naturally 'tagged' by parasites. However, if they do not pass the parasites-endemic. area, they will harbour no parasites. Therefore, researchers can discriminate each fish stocks and trace their migration routes with these biological tags. In this paper, several examples on the use of parasites as biological tags for studying salmonids, as well as other species, are listed. The advantages and limitations of parasites as biological tags are also discussed. Chum salmon (Oncorhynchus keta), the main salmonid species migrating to Korea, is distributed all around the North Pacific. Korean chum salmon are generally thought to move to the Sea of Okhotsk, the western North Pacific and the Bering Sea. However, there is no clear information on the distribution and migration pathways of Korean chum salmon, and no markers exist for separating them from others yet. Recent Korean chum salmon stock analysis including parasites information are mentioned.

• The Korean Journal of Zoology
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• v.33 no.4
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• pp.428-434
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• 1990

Uptake and accumulation of vitellogenin into ovary were traced by radiolabeled vitellogenin produced in the fat body. Vitellogenin reached the oocytes through the follicle cells and the intercellular space and penetrated the oocyte membrane via the endocytotic vesicles and then accumulated to the growing yolk granules.

• Journal of Wetlands Research
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• v.20 no.4
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• pp.295-303
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• 2018

Inland wetlands in the Republic of Korea provide key breeding and wintering habitats, while coastal wetlands provide nutrient-rich habitats for stopover sites for East Asia/Australasia Flyway(EAAF) migrants. However, since the 1960's, Korea has reclaimed these coastal wetlands gradually for agriculture and urban expansion. The habitat loss has rippled across global populations of migrant shorebirds in EAAF. To protect a similar loss, the United States, specifically Missouri, developed the moist-soil management technique. Wetland impoundments are constructed from levees with water-flow control gates with specific soils, topography, available water sources, and target goals. The impoundments are subjected to a combination of carefully timed and regulated flooding and drawdown regimes with occasional soil disturbance. This serves a dual purpose of removing undesirable vegetation, while maximizing habitat and forage for wildlife. Flooding and drawdown schedules must be dynamic with constantly shifting climate conditions. Korea's latitude ($N33^{\circ}25^{\prime}{\sim}N38^{\circ}37^{\prime}$) is comparable to Missouri ($N36^{\circ}69^{\prime}{\sim}N40^{\circ}41^{\prime}$); as such, moist-soil management could prove to be an effective wetland restoration technique for Korea. In order to meet specific conservation goals (i.e. shorebird staging site restoration), it is necessary to test the proposed methodology on a site that can meet the required specifications for moist-soil management. Moist-soil management has the potential to not only create key habitat for endangered wildlife, but also provide valuable ecosystem services, including water filtration.

• The Korean Journal of Zoology
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• v.34 no.2
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• pp.188-195
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• 1991

The effect of lanthanum ion (La3 +), which is associated with the mobilization of internal calcium, on the regulation of oocyte maturation was investigated with Rana dybowskii follicles. Follicular oocytes matured (germinal vesicle breakdown, GVBD) dose dependently when they were exposed to La3+ (O.O1-1.O mM) and the maturation occurred in 9-12 hours after the la3+(0.33 mM) stimulation. lanthanum also accelerated the onset of maturation of the lollicular oocytes exhibiting spontaneous maturation. Three hours of exposure to La3+ was enough to induce the maturation. The La3 + -induced maturation was not associated with progesterone production by follicle cells, and the maturation was inhibited by forskolin (9 $\mu$ M), and cyclobeximide (0.01 - 1.0 - $\mu$g/2 ml) in the medium. The La3+ and hormone stimulated maturation showed the same patterns of protein phosphorylation and dephosphorylation during the maturation. The data suggest that the oocyte maturation by La3+ stimulation is very similar to that by progesterone. Thus, it seems that internal mobilization of Ca2+ plays a key role in the initiation of oocyte maturation in amphibia.

• The Korean Journal of Zoology
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• v.33 no.3
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• pp.266-275
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• 1990

c-raf protein kinase, a kind of oncogene, is a cytopiasmic serine / threonine-specific protein and is activated by mitogenic or oncogenic signals. The strncture and functions of c-raf protein kinase are considered very similar to those of protein kinase C. Using immunocytochemical approach, the time course of singal transduction of c-raf protein kinase in EC-4 cell was examined with 12-0-tetradecanoylphorbol-13-acetate (TPA) as tumor promotor and plateletderived growth factor (PDGF) as mitogenic factor. Immunoreactive c-raf was initially bound to the perinuclear membrane and then moved into the nucleus. The effect of the long-term treatment with TPA or PDGF was taken place down regulation at different time point. These results indicate that TPA and PDGF give rise to the translocation of c-raf protein kinase through the two different pathways.

• Journal of Life Science
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• v.33 no.11
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• pp.950-955
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• 2023

Cell division is an essential process for the survival and development of living organisms. It is critical that duplicated chromosomes are properly segregated into daughter cells during mitosis. The centrosome is the core organelle that forms the microtubule-organizing center (MTOC), which generates the microtubules that make up the mitotic spindle during cell division. The centrosome is also involved in cell signaling and motility. In normal cells, there is one centrosome in G1 that replicates into two in the S phase and matures through G2. During the M phase, duplicated centrosomes move to both ends of the cell, and spindle microtubules that are generated from MTOC move the chromosome to both ends. The cells then split into two to complete the cell division. However, a phenomenon called centrosome amplification (CA), in which the number of centrosomes is higher than normal, is common in cancer cells and can lead to chromosome instability (CIN). This paper discusses the process of centrosome replication and the role of PLK4 in this process. The possible consequences of centrosome amplification and how the PLK4 inhibitor may be able to treat certain types of cancer cells, such as breast cancer and neuroblastoma, will also be discussed.

• KSBB Journal
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• v.24 no.5
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• pp.425-431
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• 2009

Hepatocyte growth factor (HGF) and its receptor play an important role in the formation and progression of glioma. In this study, I investigated the ability of HGF to recover of the PSA siRNA-suppressed cell proliferation, migration and invasion in U-251-MG cells. PSA siRNA-transfected U-251-MG cells showed the reduction of the proliferation, migration and invasion with compared to control. Treatment of HGF on the PSA siRNA-transfected U-251-MG cells recovered the ability of proliferation, migration and invasion. These data suggest that PSA and HGF may use unique and parallel signaling cascade leading to the proliferative, migrative and invasive phenotype of U-251-MG cells. I also showed that PSA cooperated with HGF to a migrative and invasive phenotype via the increased secretion of matrix metalloproteinase-2 (MMP-2) and MMP-9.

• Journal of the Korean Geographical Society
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• v.47 no.2
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• pp.193-207
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• 2012

This study discussed characteristics of Shindu Coastal Dune as habitat, and relationship between geodiversity and biodiversity. It was identified spatio-temporal variation of incoming nutrients depended on geomorphic differences of foredunes. The main incoming path of nutrients into coastal dune was considered as influx with movement of wind blown sands from the beach and tidal f lat. Concentrations of Na, Mg, K, Ca, and P in blown sands were compared. Concentrations of Na, Mg, and K showed high and irregular pattern in favorable condition of influx of blown sand. So these nutrients were related with geomorphic characteristics of foredunes. However, Na was also influenced by other factor such as salt spray. P was independent from effects of sea water and blown sands. In the case of Ca, a large coastal dune system rather than localized forms of foredunes made differences in the variation. Due to differences in spatio-temporal variation of nutrients, patterns of major vegetation could be inferred to appear differently. This study shows geomorphic dynamics of coastal dunes as habitat, and will provide information for coastal dune management and for understanding biological distribution and growth pattern in coastal dune.

• KSBB Journal
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• v.24 no.2
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• pp.113-121
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• 2009

As one of the new areas of 'omics' technology, there is increasing interest in metabolomics, which involves the analysis of low-molecular-weight compounds in cells, tissues, and biofluids, and considers interactions within various organisms and reactions of external chemicals with those organisms. However, metabolomics research is still at a fundamental stage in Korea. Therefore, the purpose of this study was to establish a strategic long-term plan to revitalize the national metabolomics approach and obtain the elementary data necessary to determine a policy for effectively supporting metabolomics research. These investigations clarified the state of metabolomics study both in Korea and internationally, from which we attempted to find the potentiality and fields where a metabolomics approach would be applicable, such as in medical science. We also discuss strategies for developing metabolomics research. This study revealed that promoting metabolomics in Korea requires cooperation with metabolomics researchers, acquisition of advanced technology, capital investment in metabolomics approach, establishment of metabolome database, and education of metabolome analysis experts. This would reduce the gap between the national and international levels of metabolomics research, with the resulting developments in metabolomics having the potential to greatly contribute to promoting biotechnology in Korea.