• Title/Summary/Keyword: 생리학

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A Study of Portability and Mobility for Infantry Weapon System (보병용 무기체계의 휴대성 및 이동성에 관한 연구)

  • Chung, SungHak;Son, SungHan
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2013.07a
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    • pp.141-143
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    • 2013
  • 본 연구에서는 인력물자취급시 역사적 관점에서 생리학적 연구방법, 생체역학적 연구방법, 인체심리학적 연구방법들을 검토하여 보병용 무기체계의 휴대성 및 이동성을 분석하였다. 본 연구에서는 휴대성과 이동성 간의 관계를 도식하였다. 단거리의 짧은 기동거리에서는 생체역학적 기준치를, 1-2시간의 중간인 이동에서는 인체심리학적 기준치를, 4시간 혹은 그 이상의 장거리에서는 생리학적 기준치를 적용하여 각각의 가이드라인들을 상호 절충하는 것이 필요한 것으로 판단된다. 본 연구에서는 보병의 물자취급시 4가지 연구방법을 제안하였다.

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특집 - 전문의가 바라본 2008년 당뇨병 치료 변화 패턴

  • Park, Jeong-Hyeon
    • The Monthly Diabetes
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    • s.217
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    • pp.27-31
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    • 2007
  • 의학은 항상 변화하고 발전하는 학문이다. 특히 최근 임상의 학은 눈부시게 빠른 속도로 발전해가고 있다. 당뇨병의 치료 분야는 임상의학의 모든 분야를 통틀어 가장 빠르게 발전하고 있는 분야의 하나로 해가 갈수록 이전과는 다른 내용의 과학적 정보들 및 진료지침들이 만들어지고 있다. 하지만 이러한 발전에도 불구하고 아직도 우리가 당뇨병의 병태생리에 대해 알고 있는 지식과 당뇨병을 치료하기 위해 가지고 있는 기술은 1921년 인슐린이 발견된 이래로 크게 진보된 것은 없다고 생각한다. 아직도 많이 불완전한 치료 방법들만을 너무 맹신하고 당뇨병의 보다 근본적인 병태생리가 되는 생활습관의 왜곡에 대해 보다 적극적으로 개입하지 않는 것은 크게 잘못된 것이다. 2008년에는 당뇨병을 앓고 있는 모든 환자분들과 당뇨병 치료에 관련된 모든 의학계의 분들이 같이 노력해서 잘못된 관행과 습관 및 제도 등을 개선하고, 약물에만 의존할 것이 아니라 잘못된 생활 습관을 제대로 교정하려는 노력도 함께 기울였으면 한다.

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Effects of Kangaroo Care on Physiological Marker of Preterm Infant in Neonatal Intensive Care Unit (캥거루식 접촉이 신생아 집중치료실 미숙아의 생리적 지수에 미치는 효과)

  • Lee, Sang Bok;Shin, Hye Sook
    • Journal of East-West Nursing Research
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    • v.18 no.2
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    • pp.59-65
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    • 2012
  • Purpose: The purpose of this study was to examine the effects of Kangaroo Care (KC) on physiological marker of preterm infant in neonatal intensive care unit (NICU). Methods: The research design was a nonequivalent control group pretest-posttest. Data were collected from July 1, 2007 to February 29, 2008. The participants were 26 people of experimental group and 27 people of control group. KC was applied three times per day, for a total ten times of 4 days to the experimental group. Results: There was significant difference between experimental and control groups on the skin temperature on of preterm infants. The skin temperature in the intervention group was significantly higher than in the control group. Conclusion: Kangaroo care can be applied as a supportive nursing intervention to preterm infant at neonatal intensive care unit.

The Effect of Participation on Health Care Patterns in a disease Aged Physical Activities (신체활동이 노인성 질환의 건강관리에 미치는 영향)

  • Kim, Yong-Nan;Ru, Jae-Mon
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.2 no.2
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    • pp.51-59
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    • 2004
  • The purpose of this study was to analyze. The effect of participation physical activities on health care patterns in the aged. The subject of the study was selected by multi-stage stratified cluster random sampling among the aged center and aged club to participate program whose age were 65 and over year old among inhabitant the Kwangju metropolitan area. The data were collected through a questionnaire adapted from Payne and Hahn's(1986) 'Understanding Your Health-A personal profile; Evaluating Your Health'. The pilot test was executed after the questionnaire was translated into Korean.

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Maximal Voluntary Contraction and Muscle Thickness Relationship in Skeletal Muscle (골격근에서 최대 수의적 등척성 수축력과 근 두께와의 관계)

  • Jeong, Jin-Gyu;Kim, Yang-Ho;Kim, Tae-Youl
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.2 no.2
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    • pp.25-37
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    • 2004
  • To provide reflection diagnostical basic-data by ultrasonography intended for 38 male/female students used by ultrasound imaging system and dynamometer, compared the MVIC and muscle thickness take an accurate measurement of elbow flexor and knee extensor of thickness and MVIC, in confirmity with distinction of sex and then analysised of correlation in muscle thickness-MVIC, MVIC-weight, weight-muscle thickness, it shows statiscally significant difference MVIC and muscle thickness according to sex. Also there is a high interrelation between two. As well as it shows that there is a different between sex in the MVIC of same thickness and MVIC of same weight. This difference will be related with preportions of muscle fiber type in view of the results by preceded research, it needs to be prerequisite analysis of difference in sex with a great variety of ways hereafter.

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Novel Lead Optimization Strategy Using Quantitative Structure-Activity Relationship and Physiologically-Based Pharmacokinetics Modeling (정량적 구조-활성 상관 관계와 생리학 기반 약물동태를 사용한 새로운 선도물질 최적화 전략)

  • Byeon, Jin-Ju;Park, Min-Ho;Shin, Seok-Ho;Shin, Young Geun
    • YAKHAK HOEJI
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    • v.59 no.4
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    • pp.151-157
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    • 2015
  • The purpose of this study is to demonstrate how lead compounds are best optimized with the application of in silico QSAR and PBPK modeling at the early drug discovery stage. Several predictive QSAR models such as $IC_{50}$ potency model, intrinsic clearance model and brain penetration model were built and applied to a set of virtually synthesized library of the BACE1 inhibitors. Selected candidate compounds were also applied to the PBPK modeling for comparison between the predicted animal pharmacokinetic parameters and the observed ones in vivo. This novel lead optimization strategy using QSAR and PBPK modelings could be helpful to expedite the drug discovery process.

Building an Ontology for Structured Data Entry of Signs and Symptoms in Oriental Medicine (Protege를 이용한 한의학의 구조화된 증상 입력을 위한 온톨로지 개발)

  • Park Kyung Mo;Lim Hee Sook;Park Jong Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.5
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    • pp.1151-1156
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    • 2003
  • To obtain both of the fast and complete data entry and the acquisition of reusable data in a Computer-based Patient Record system (CPR), we are building the ontology that is used by the entry supporting agents. Our application domain is Traditional Chinese Medicine. As the tool for the implementation, we used protege 2000 which is ontology building tool and provides frame knowledge representation language. In this paper, the construction methodology of our ontology is reported.

Application of Systems Biology to Korean Medicine Research - Need for Paradigm Shift (시스템 생물학과 한의학 연구 - 발상의 대전환 필요)

  • Earm, Yung E
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.30 no.6
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    • pp.367-369
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    • 2016
  • The recent introduction of the systems biology or systems medicine opens a new horizon in the field of traditional oriental medicine research. Until now many recent researches of traditional medicine have been conducted based upon reductionist approach, but traditional medicine should be treated by a holistic approach. In this short review, I outlined usefulness of systems approach in medicine and proposed a potential application area of traditional medicine research.

Guide to Learning Systems Biology for Korean Medicine Researchers (한의학 연구자를 위한 시스템 생물학 학습 가이드)

  • Kim, Chang-Eop
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.30 no.6
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    • pp.412-418
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    • 2016
  • The emergence of systems biology in the 21st century is changing the paradigm of biomedical research. Whereas the reductionist approaches focus on components rather than time or contexts, systems biology focus more on interrelationships, dynamics, and contexts. The key ideas of the systems biology shares much with the philosophy of Korean Medicine(KM) and therefore, the paradigm shift is shedding light on understanding the mechanism of action of KM at system level. In this article, I provide a guide to learning systems biology for KM researchers using online learning resources. Thanks to the recent development of MOOC(massive open online courses) and other online learning platforms, learners can access to plenty of high-quality resources from top-tier universities in the world. I expect this guide help researchers to employ systems biology methods into their KM researches, and will lead to the development of future curricula for training "bi-lingual" experts, KM and computational approaches.

Study on the Concept and Its Structure of Visceral System in Current Traditional Korean Medicine (현대 한의학의 장부 개념과 구성 체계에 관한 연구)

  • Kim, Myung Hyun;Kim, Byoung Soo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.31 no.6
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    • pp.305-312
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    • 2017
  • Theory of visceral and meridian system is the most important part in traditional Korean medicine. In theory of visceral system, the aspect of function has been emphasized more than anatomical substance. In this research, the concept of visceral system would be attempted to be expanded from 'five viscera and six bowels' to whole body, and new analysis system composed of genesis, structure, function and operation. The theories of traditional Korean medicine remain at the organ system or organ level, therefore progressive research using the new analysis system is needed to approach tissue and cell levels.