• 동의생리병리학회지
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• 제36권2호
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• pp.41-47
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• 2022

Postherpetic neuralgia(PHN) is one of the most common intractable chronic pain syndromes. This review was conducted to investigates the trends in recent clinical studies of PHN in China and to find out the efficacy of Chinese medicine treatment for PHN. Based on CNKI databases, nineteen randomized controlled trials(RCTs) were analyzed. The search focused on the authors, publication year, sample size, age, duration of illness, treatment period, lesion sites, methods, outcome measures, and results of the selected articles. Four studies used herbal medicine. The most frequently used herbs were Angelicae Gigantis Radix(當歸) and Corydalis Tube(玄胡索). Eighteen studies used acupuncture treatment. The most frequently used acupoints were ST36, LR3, LI4. Three studies used moxibustion and 5 studies used cupping treatment. In all nineteen studies, the efficacy of Chinese medicine treatments was confirmed. More varied and scientifically designed clinical studies are required to develop treatments for PHN. The results of current study could be used as guidance for further studies of treatment on PHN.

• 동의생리병리학회지
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• 제36권1호
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• pp.7-10
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• 2022

Hwangryunagyo-tang (HT) is a herbal cocktail to treat insomnia induced by yin deficiency with effulgent fire. In the present study, the onset time and the duration time of sleep were measured 30 minutes after thiopental sodium injection. And c-fos immunohistochemistry was performed to find the activated nerve cells of the ventrolateral preoptic nucleus (VLPO) and tuberomammillary nucleus (TMN) sites in the brain. HT significantly increased the number of activated nerve cells in the sleep-inducing center (VLPO), whereas HT significantly decreased the number of activated nerve cells in the arousal center (TMN). It could be concluded that the HT shortened the onset time and increased the duration time for sleep induced by thiopental sodium. And it was confirmed that the mechanism acted by activating the sleep-inducing center (VLPO) and suppressing the arousal center (TMN) in the brain. The results are considered to be useful as scientific evidence HT can be used clinically for the treatment of insomnia caused by yin deficiency with effulgent fire.

• 동의생리병리학회지
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• 제36권1호
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• pp.23-27
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• 2022

This study aims to evaluate the anti-inflammatory effect of 80% ethanol extracts of Stachys affinis (MQ) on 1-fluoro-2,4-Dinitrofluorobenzene (DNFB) induced atopic dermatitis (AD) in Balb/c mice. AD-like allergic contact dermatitis was induced by challenge of DNFB on the ear after DNFB sensitization on the back sides of mice. MQ alleivated clinical severity in AD-like skin lesions. In addition, ear thickness of epidermis and penetration of inflammatory cells in AD-like skin lesions were decreased by topical application of MQ. The the serum levels of tumor necrosis factor-α (TNF-α) and interleukin-4 (IL-4) were measured in AD mice using ELISA kits. Levels of TNF-α and IL-4 in serum were significantly decreased by topical application of MQ. Therefore, this study could give a clinical basis that MQ could be a agent to prevent AD.

• 산업융합연구
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• 제21권2호
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• pp.85-92
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• 2023

비정상적인 척추 질환 및 기능은 단순한 근·골격계 문제 외에도 항상성을 방해하고 직·간접적인 생리적 부작용을 일으킬 수 있다. 특히 척추를 통해 나오는 신경이 면역체계를 조절하는 기관에 적절한 신호를 전달하지 못하면 면역 기능의 일부 또는 전부에 문제가 생겨 더 많은 질병에 노출될 수 있다. 이 연구는 기본적인 해부학 및 생리학적 지식에 초점을 맞추고 척추 기능이 잠재적으로 면역 기능을 유지하거나 개선하는 데 도움이 될 수 있는 잠재적 메커니즘을 고찰하고자 한다. 이를 위해 조혈, 스트레스, 호흡, 척추와 신경의 관계, 면역체계와 관련된 척추의 역할을 살펴보고 이러한 역할이 면역기능에 영향을 미칠 수 있음을 확인한다.

• 동의생리병리학회지
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• 제36권6호
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• pp.221-228
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• 2022

The purpose of this study is to report the research trends of Korean medicine treatment for alopecia areata. We investigated the studies on Korean medicine treatments for alopecia areata via searching 4 web databases of Korea. 13 papers were selected, and we classified them according to publication year, published journals, the types of study, research subject, the methods of treatment, confirmation of recurrence, methods of evaluation, and institutional review board(IRB). We analyzed a total of 13 clinical studies of Korean medicine on alopecia areata based on various criteria and reviewed the research trends. Based on this, we suggested points to be improved and supplemented when conducting clinical research on alopecia areata in the future. Clinical studies on alopecia areata started to be published in 2001, and acupuncture, pharmacopuncture, herbal medicines, etc. were used as treatment methods for alopecia areata. Most of the clinical studies on alopecia areata were case studies, so it is thought that various types of clinical studies are needed. In addition, it is necessary to confirm the recurrence of alopecia areata and to improve the awareness of research ethics.

• 한국가축번식학회지
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• 제19권4호
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• pp.323-329
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• 1996

미성숙난자 성장과 핵성숙을 성공적으로 유도할 수 있는 체외 배양체계의 개발은 난자발생과정 등 기초 생리학 연구에 도움을 줄 뿐만 아니라, 산업적으로 필요한 난자를 공급해 줄 수 있다는 데 그 의의가 있다. 최근 보고에 따르면 성장 중에 있는 생쥐 난포란은 체외배양과 체외수정과정을 거쳐 산자 생산가지 가능하지만 돼지 난포란 성숙을 위해서는 좀더 고려해야 할 사항들이 있다. 즉, 난성숙 배양액에 낮은 농도의 FSH 첨가는 난자와 과립세포의 생존성을 유지시키고, Hypoxanthine의 첨가는 난성숙율의 향상에 도움을 준다고 한다. 따라서 금후 생쥐난자에서 얻어진 결과들을 기초로 하여 돼지 난포란의 성장과 성숙에 적합한 배양체계의 개발연구에서 괄목할만한 진전이 있다면 대가축들의 난포란 성숙기술을 개발하는데 큰 도움을 줄 것이라고 본다.

• 동의생리병리학회지
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• 제16권5호
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• pp.845-850
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• 2002

This paper suggest a methodology for representation of findings which can be called as signs and symptoms. A finding consists of unit signs and unit symptoms, and moreover findings which appear in one individual patient have so many different relationship each other. So, it is nat appropriate to list all of possible findings as medical standard or to fill findings as independent things in paper for medical record. We try to distinguish finding item from finding list, and suggest the methodology by which we can make finding list from finding items. That is, we suggest finding item[Concept], value types, relationship, logical operator, and syntax as a component of representation. And by using urinary symptom, we make the example for representation methodology. Finally, we mention the background knowledge, brief research process of related area.

• 동의생리병리학회지
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• 제18권3호
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• pp.939-941
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• 2004

Phototherapy have perpetual history, we can see an instance of it in Yellow Emperor's Conon of Medicine(黃帝內經) and Laser therapy is a field of Phototherapy being used frequently in the latest time. We treated patients with telangiectasia by laser therapy and experimented it's efficacy and studied the means of clinical application in Korean medicine. We report the capabilities of application of laser therapy, based on Korean medical theories by using resemblance between laser therapy with kyung-rak(經絡) control technique in the line that connects with the past.

• 대한간호학회지
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• 제35권1호
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• pp.143-153
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• 2005

Purpose: This study was aimed at finding the effects of cycled lighting on body weight, physiological variables and the behavioral state of LBWI (low birth weight infants) in the NICU. Method: The subjects were 20 LBWI at 2 NICUs. They were assigned to an experimental or control group which consisted of 10 subjects in each. Cycled light was applied to the experimental group for 10 days. Result: It was certified that the application of cycled lighting resulted in increased body weight and O2 saturation, and decreased heart rate of the LBWI. However, there was no effect in decrease of respiration and stabilization of the behavioral state. Conclusion: The application of cycled lighting might be a nursing intervention which would in turn have positive effects on the growth of LBWI.

• 성인간호학회지
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• 제22권5호
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• pp.529-536
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• 2010

Purpose: This study was designed to identify the effect of auriculotherapy on low abdominal pain and dysmenorrhea in school-aged girls. Methods: This design was a pre and post-test with nonequivalent groups. The subjects were 71 girls who were middle school students with dysmenorrheal (35 students for the treatment group and 36 students for the comparison group). The subjects of the treatment group received auriculotherapy once a week for 10 weeks. The comparison group received instruction on auriculotherapy and was requested waiting for the order. Results: The treatment group reported significantly less low abdominal pain than the comparison group. However, there were not statistical differences in reported dysmenorrhea. In future analysis, 60.0% of the treatment group reported more physical comfort, and 45.7% reported more emotional cool down. Conclusion: The finding indicate that auriculotherapy could be effective in decreasing low abdominal pain during menstrual periods. Therefore, auriculotherapy could be an effective nursing intervention for low abdominal pain occurring during mensuration. However, further studies need to be done to support auriculotherapy as effective.