• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.9
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• pp.1345-1350
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• 2013

The objective of this study was to evaluate the effect of extraction methods on the antioxidant activity of Citrus unshiu pomace. For this purpose, two kinds of citrus pomace (CP)s, whole fruit CP and pulp CP, were used for preparing the extracts with hot water or 70% ethanol. It is well-known fact that whole fruit CP has more calories and carbohydrates, although moisture content is higher in pulp CP. Further, whole fruit CP extracts have higher levels of total phenolic contents compared to CP extracts. In addition, DPPH and alkyl radical scavenging activities were also higher in whole fruit CP, especially in ethanolic extracts. Our results based on liquid chromatography-mass spectrometer showed that 70% ethanolic extract of whole fruit CP has the maximum levels of nobiletin and tangeretin contents. The levels of naringin, which is known as an antioxidant flavonoid, was determined only in the 70% ethanolic extract of whole fruit CP. This result, however, is consistent with the observed DPPH and alkyl radical scavenging activities. We had also performed a gas chromatography analysis that showed all the four extracts contained the compound hydroxymethyl furfural. Significantly, this compound has been reported to have antioxidant activity. Taken together, findings of this study indicate that ethanolic extraction of whole fruit CP is a good source of antioxidant compounds and hence the same could be utilized as an important method to obtain such beneficial compounds on an industrial scale.

• The Journal of Internal Korean Medicine
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• v.26 no.4
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• pp.761-766
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• 2005

Objectives : 본 연구는 암환자의 위장관 기능장애를 개선시킬수 있는 보다 효과적인 약물개발의 일환으로 곽향 추출물의 장운동에 미치는 영향을 평가하기 위해 수행되어졌다. Methods : 생리적인 상태에서 곽향추출물이 장운동에 미치는 영향을 알아보기 위해 장운동촉진제인 carbachol과 곽향추출물을 실험쥐들에게 투여후 15분후 charcoal meal을 먹여서 charcoal meal의 소장내 통과 정도를 비교 측정하였다. 또, loperamide, scopolamine, nicotine으로 장운동을 억제시켜 놓은 실험쥐들에 15분 간격으로 곽향 추출물과 charcoal meal을 먹인 후 역시 charcoal meal의 소장내 통과 정도를 비교 측정하였다. Results : 곽향 추출물은 생리상태에서는 장운동에 영향을 미치지 않았다. 곽향추출물은 loperamide와 scopolamine으로 유발된 장운동 억제상태에 대하여 부분적으로 영향을 끼쳤다. 그러나 nicotine으로 유발된 상태에 대해서는 영항을 끼치지 않았다. Conclusion : 곽향 추출물은 소화관 기능부전 완화에 효과적으로 작용하는 천연물이라 추론할 수 있다.

• The Journal of Korean Academic Society of Nursing Education
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• v.5 no.2
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• pp.359-375
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• 1999

This is a survey in order to provide basic information about menstrual pain management and dysmenorrhea management. Menstrual pain means low abdominal cramps during menstruation and dysmenorrhea means low abdominal pains, and other symtoms as lumbago, fatigue, G-I symptoms, etc. The purposes of this study were (1) to measure the menstrual pain and dysmenorrhea, (2) to determine factors influenced to them, and (3) to know self-management method for them of college students. The subject of this study consisted of 312 college students Data were collected by questionnaire which was to measure the menstrual pain(Visual Analogue Scale(VAS), dysmenorrhea (dysmenorrhea scale) and general informations from May to June, 1999. The results of this study were as follows ; (1) Mean age for subjects was 19.4 yrs, their height was 161.4Cm, weight, 50.9Kg, menarcheal age, 13.5yrs, menstural period, 30.1 days, and menstrual duration was 5.6 days. Most respondents replied that their menstrual bleeding was moderate (72.1%) and occured regularly(55.4%). (2) Mean menstrual pain was 5.20. Menstrual pain didn't be occured 17.4 % of respondents, periodically 46.0%, and intermittently 36.6%, most commonly beginning the first day of menstruation (3) Chief management method was endurance (40.4%), use of analgesics (29.5%) and bed rest(16.5%). (4) Factors influenced to menstrual pain were analgesics use, heavy bleeding, time of menstrual pain, life change during menstruation. (5) Most symptoms of dysmenorrhea were low abdominal pain(22.2%), lumbago (15.9%), fatigue(9.0%). (6) Factors influenced to dysmenorrhea were anlgesics use and menstrual pain. (7) By Pearson's correlation analysis, there was a significant correlation between menstrual pain and menarcheal age, menstrual period. menstrual duration. But there was no correlation between menstrual pain and height, weight (8) By Pearson's correlation analysis, there was a significant correlation between dysmenorrhea and menstrual period But there was no correlation between menstrual pain and menarcheal age, menstrual duration, height, weight The results demonstrate the importance of development and clinical trial of nursing intervention on menstrual pain and dysmenorrhea.

• Research in Community and Public Health Nursing
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• v.14 no.3
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• pp.432-444
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• 2003

Purpose: This study attempted to verify the effect of Koryo hand therapy on menstrual cramps and dysmenorrhea among college students. Method: This study performed the quasi-experimental design with nonequivalent control group and the pre and post-test design from August 28 to November 4, 2002. The subjects of this experimental study consisted of 64 college students in the nursing college of K University in D city and K college students in K city, who had more than 5.0 GRS score of menstrual cramps. Among them, 16 people belonged to the experimental group A by using Ceramic Seo Am moxa therapy, 16 to the experimental group B by using Seo Am pellet therapy, 16 to the experimental group C by using combination of Ceramic Seo Am moxa therapy and Seo Am pellet therapy and 16 to the control group. Three different kinds of methods were used three times per week for $5{\sim}6$ weeks(a total of $15{\sim}18$ times) interventions were completed. For the experimental group, A Ceramic Seo Am moxa therapy was given for 40 minutes per each treatment; for the experimental group, B Seo Am pellet therapy was given for 4 hours: for the experimental group, C combination of Ceramic Seo Am moxa therapy and Seo Am pellet therapy was given. To measure menstrual cramps, the graphic rating scale (GRS) was used and to measure dysmenorrheal, a dysmenorrhea scale (15 contents) was used, which was modified from Han &Hur's scale (13 contents). Cronbach's was 0.78 in the pre-test, 0.83 in the first post-test, 0.89 in the following post-test. Data were analyzed by one-way ANOVA, 2 test, repeated measures ANOVA, time contrast test and Sheffe test with the SPSS/Win 11.0 program. Results: ? The first hypothesis, 'Among the experimental group A by using Ceramic Seo Am moxa therapy, the experimental group B by using Seo Am pellet therapy and the experimental group C by using combination of Ceramic Seo Am moxa therapy and Seo Am pellet therapy will have different graphic rating scores of menstrual cramps', was supported (F=6.77, p=0.000, Interaction: p=0.000). ? The second hypothesis, 'Among the experimental group A by using Ceramic Seo Am moxa therapy, the experimental group B by using Seo Am pellet therapy, the experimental group C by using combination of Ceramic Seo Am moxa therapy and Seo Am pellet therapy and the control group will have a significantly different level of dysmenorrhea', was supported (F=6.88, p=0.000, Interaction: p=0.000). From the above results, it can be an effective nursing intervention to give Koryo hand therapy to college students who have menstrual cramps and dysmenorrhea. Conclusion: These findings indicate that Koryo hand therapy could be applied to improve the quality of life and to prevent drug misuse among college students who are physically, mentally and psychologically suffering from menstrual cramps and dysmenorrhea. Furthermore, Koryo hand therapy could be developed as an effective Korean alternative and complementary care in the future. and it could also provide a guideline to apply Koryo hand therapy to other pain and difficulties.

• The Journal of Dong Guk Oriental Medicine
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• v.7 no.2
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• pp.1-8
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• 1999

This paper documents a holistic study of the kidney and its symptom. To this end, the relationship between internal organs and its diseases have been studied from th e viewpoint of the connecting role of the kidney channel of foot-shaoyin. The results of this study are as follows; The function of the kidney has specific re lations with the liver, lung, heart, urinary bladder, throat, tongue, chest, sole of the foot, inside of the thigh and waist. These mutual relations reflect the pathological changes of the kidney. So physiological function and symptom of the kidney can be better understood throu gh the connecting role of the kidney channel of foot-shaoyin on the concept of the organism as a whole. This is the key of the clinical treatment based on the precept sof oriental medicine.

• Journal of Korean Society of Forest Science
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• v.85 no.1
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• pp.120-129
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• 1996

This study was carried out to investigate the hydraulic architecture such as relative hydraulic conductivity, Leaf specific conductivity(LSC), Huber value, Specific conductivity of the stem, branch and Junctions of stem-to-branch in Quercus mongolica trees. The hydraulic architecture of various hydraulic conductivities of stem and branch was described. The results obtained were summarized as follows : 1. The range of relative hydraulic conductivity was $2.5526{\times}10^{-12}$ to $1.2260{\times}10^{-10}m^2$ in stems, $1.6279{\times}10^{-11}$ to $6.8378{\times}10^{-11}m^2$ in branches. The relative hydraulic conductivities increased with decreasing diameter of stem and branch. The relative hydraulic conductivity of one-year-old terminal shoots were two times greater than that of the lateral shoots. 2. LSC value was larger at the top than at the base in stem. LSC is much smaller in branches than in stem ; especially smallest at branching part. 3. Hydraulic conductivities of the branching part appeared the different values with the 4 type and 4 type. Relative hydraulic conductivity, LSC, Specific conductivity and mean vessel diameter in type branching part were larger in stem than in branch part, but not found in the branching part of Y type. 4. LSC and Specific conductivity of stem increased with decreasing diameter, but Huber value slowly increased with decreasing diameter ; especially highest at less than 1cm diameter. 5. LSC, Huber value, and mean diameter of vessels were larger at 1-year-old leader shoots than at lateral shoots. 6. The mean vessel diameter in various parts of a tree decreased with decreasing diameter of stem, but the number of vessels per unit area($mm^{-2}$) increased reversely. Mean vessel diameter in stem decreased sharply at earlywood and slowly at latewood with decreasing diameter of stem.

• Journal of Korean Society of Forest Science
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• v.87 no.2
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• pp.220-229
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• 1998

This study was performed to compare the characteristics of hydraulic conductivity such as relative conductivity(RC), leaf specific conductivity(LSC), Huber value(HV), specific conductivity(SC), and diameter of vessels(${\mu}m$) and number of vessels($No./mm^2$) in branch junctions of the twenty-one deciduous broad-leaved species. The hydraulic conductivities of branch junctions decreased with increasing junction angle between stem and branch, and with decreasing diameter of branch. The RC and LSC of branch junctions related to branching types(ㅏ, Y, ${\Psi}$ type) were much lower in ㅏ and ${\Psi}$ types than in Y type. The diameter and number of vessels remarkably reduced in branch junctions as compared with the stem and branch.

• Journal of muscle and joint health
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• v.28 no.1
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• pp.41-49
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• 2021

Purpose: This study aimed to compare the effects of the Difflam spray 0.3% with the sodium bicarbonate-normal saline spray on oral care for postoperative patients. Methods: The participants were randomly allocated to either the Difflam (n=22) group or the saline solution (n=23) group. The data were collected at the 1-, 4-, 7-, and 10-hour marks after returning to the ward post operation using the Beck's subjective oral discomfort scale, Visual Analogue Scale for sore throat, and portable halitosis detector. Results: The sore throat (F=7.25, p=.001) score significantly decreased after oral care using the Difflam spray 0.3%. However, the difference in the scores of oral comfort (F=0.34, p=.797) and halitosis (F=0.91, p=.443) between the two groups was not statistically significant. Conclusion: These findings suggest that the Difflam spray 0.3% is effective in improving postoperative sore throat. A further study that explores the effect of various oral solutions for postoperative patients is needed to present systemic and effective evidence-based oral care guidelines.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.1 no.1
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• pp.45-56
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• 2003

This study investigated the effects of triamcinolone acetonide by iontophoretic transdermal drug delivery on anti-inflammatory action into the human which had excentric exercise-induced delayed onset muscle soreness in the non-dominant arm. The degree of anti-inflammation was evaluated creatine posphokinase(CPK) by serum enzyme activity and subjective pain threshold by soreness muscle scale in clinical study. The results Were as follows; 1. In a subjective pain scale, all groups showed non-significant difference but, showed a tendency to decrease numerical value in human. 2. In the serum CPK level, iontophoresis group showed more significant reduction than other groups at 24, 48 and 72 hours. From the results, the iontophoresis with triamcinolone acetonide is more effective than using each groups. The continuous study is needed for many interesting issues of iontophoretic transdermal drug delivery in new future.

• Journal of Korean Academy of Nursing
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• v.32 no.3
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• pp.317-326
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• 2002

The purpose of this study was to verify the effect of aromatherapy on the stress response in menstrual period. Method: A randomized, single-blind, pretest- posttest design was used. The study subjects were 60 college women with dysmenorrhea and they were randomized into 3 groups, experimental, 1st control(placebo) and 2nd control group. The researchers massaged treatment oil(3% dilution essential oil of Lavender, Clary sage and Rose) into the abdomen of experimental group. The placebo group used almond oil(carrier oil) instead, and the 2nd control group did not give any treatment. Baseline data including pre-treatment stress response score were obtained on the first day of usual period. Aromatherapy provided for about 7 days until the next cycle began. Post-treatment stress responses were measured by 94 item SOS(symptom of stress) scale on the first day of the cycle. Results: As a results, the stress response score of experimental group was significantly lower than two control groups. And there was no significant difference in stress responses of two control groups. Conclusion: The results show aromatherapy using selected essential oils to be an effective intervention for stress response during menstruation.