• Investigative Magnetic Resonance Imaging
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• v.4 no.1
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• pp.27-33
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• 2000

Purpose: To determine the electronic spin relaxation times, $T_{le}$, of three commercially available Gd-chelated MR contrast agents, Gd-DTPA, Gd-DTPA-BMA and Gd-DOTA, using Electron Paramagnetic Resonance(EPR) technique. Material and Methods: The paramagnetic MR contrast agents, Gd-DTFA(Magnevist) , Gd-DTFA-BMA(OMNISCAN) and Gd-DOTA(Dotarem), were used for this study, The EPR spectra of these contrast agents, which were prepared 2:1 methanol/water solution, were obtained at low temperatures, from $-160^{\circ}C~20^{\circ}C$. The glassy-state EPR spectra for these contrast agents were then fitted by the simulation spectra generated with different zero-field splitting (ZFS) parameters by a computer simulation program 'GEN', which generates the EPR powder spectrum using a given ZFS in $3{\times}3$ tensor. Finally, the spin relaxation times of the contrast agents were then determined from the $T_{2e}$, D, and E values of the best simulation spectra using the McLachlan's theory of average relaxation rate. Results: The electronic transverse spin relaxation times, $T_{2e}'s$, of Gd-DTPA, Gd-DTPA-BMA and Gd-DOTA were 0.113ns, 0.147ns and 1.81ns respectively. The g-values were 1.9737, 1.9735 and 1.9830 and the electronic spin relaxation times, $T_{1e}'s$, were 18.70ns, 33.40ns and $1.66{\mu}s$, respectively. Conclusion: The results of these studies reconfirm that the paramagnetic MR contrast agents with larger ZFS parameters should have shorter $T_{1e}'s$. Among three contrast agents used for this study, Gd-DOTA chelated with cyclic ligand structure shows better electronic property then the others with linear structure. Thus, it is concluded that the exact determination of ZFS parameters is the important factor in evaluating relaxation enhancement effect of the agents and in developing new contrast agents.

• Food Science and Preservation
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• v.5 no.4
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• pp.331-334
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• 1998

Weight loss of table Grape packed with control(Corrugated paperboard box), LDPE, CE(MA film masterbatched by ceramic powder treated cemical reagent) and FC box(laminated by CE film pouch) at 25 C after 10 days were 5.6%, 0.4%, 0.6%, and 0.7%, respectively. Weight loss of control was 7.29times higher than that of FC box. Total ascorbic acid content(TAA) of table grape after 10 days was 3.42 mg% for control, was 5.33 for LDPE and 5.14mg% for CE, 4.98mg% for FC. TAA of LDPE and CE showed to higher than that of control, especially TAA of FC was 33% higher than that of control. Titratable acid of LDPE and CE was high compare to control, and acidity of FC was 6% higher than that of control. References in overall appearance of LDPE, CE and FC were better than that of control. Corrugated paperboard box(FC) laminated with functional MA film showed to be able to used as packaging box of table grape.

• Journal of the Korean Chemical Society
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• v.29 no.2
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• pp.80-87
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• 1985

Radiation damage in a single crystal of ammonium sulfate caused by ${\gamma}$-irradiation at room temperature has given rise to several paramagnetic centers. Electron spin resonance (ESR) spectra of crystal are obtained with the X-band EPR spectrometer at room temperature. An intense and isotropic peak of Gaussian shape at g = 2.0036 is assigned to $SO_3^-$, which shows power saturation effects. Angular dependence of spectra is studied for the rotations about three mutually perpendicular axes a, b and c. The g-values are obtained from the relative distances between isotropic peak of $SO_3^-$ and anisotropic peak of the species. Principal $g^-$values and direction cosines were calculated by diagonalizing the 3${\times}$3 matrix whose elements are the $g^-$values for each species. From the analysis of characteristic principal $g^-$values and direction cosines for ammonium sulfate single crystal, anisotropic peaks corresponding to $SO_4^-,\;SO_2^-$ and defect structure corresponding to electron excess type are identified.

• Proceedings of the Korean Magnestics Society Conference
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• 1992.03a
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• pp.18-19
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• 1992

• Journal of Mushroom
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• v.17 no.3
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• pp.132-135
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• 2019

This study aimed to develop a new method of Lentinula edodes cultivation to reduce labor and waste disposal. To identify the optimum container for L. edodes cultivation, box, bottle, and bag containers were assessed for their effects on the cultural characteristics and mushroom yield. Among the three approaches, box-cultivation with 7 kg of substrate had the shortest browning period (42 days) and resulted in the highest mushroom yield (1,253 g). Contrastingly, bottle-cultivation was unsuitable for cultivation due to low production of the fruiting bodies and poor quality. Further studies on the box-cultivation approach will be required for commercial applications of L. edodes.

• Progress in Medical Physics
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• v.17 no.2
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• pp.61-66
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• 2006

To evaluate the T1, T2 magnetic relaxation properties of water molecule according to molecular weight of paramagnetic complex. 4-aminomethyicyclohexane carboxylic acid (0.63 g, 4 mmol) was mixed with the suspension solution of DMF (15 ml) and DTPA-bis-anhydride (0.71 g, 2 mmol) to synthesize the ligand. The ligand was then mixed with $Gd_2O_3$ (0.18 g, 0.5 mmol) to synthesize Gd-chelate. For the measurement of magnetic relaxivity of paramagnetic compounds, the compounds were diluted to 1 mM and then the relaxation times were measured at 1.57 (64 MHz). Inversion-recovery pulse sequence was employed for T1 relaxation measurement and CPMG (Carr-Purcell-Meiboon-Gill) pulse sequence was employed for T2 relaxation measurement. In case of inversion recovery sequence, total 35 images with different inversion time(T1)s ranging from 50 msec to 1,750 msec. To estimate the relaxation times, the signal intensity of each sample was measured using region of Interest (ROI) and then fitted by non-linear least square method to yield T1, T2 relaxation times and also R1 and R2. Compared to T1=($205.1{\pm}2.57$) msec and T2=($209.4{\pm}4.28$) msec of Omniscan (Gadodiamide), which is commercially available paramagnetic MR agent, T1 and T2 values of new paramagnetic complexes were reduced along with their molecular weight. That is, T1 value was ranged from $(96.35{\pm}2.04)\;to\;(79.38{\pm}1.55)$ msec and T2 value was ranged from $(91.02{\pm}2.08)\;to\;(76.66{\pm}1.84)$ msec. Among new paramagnetic complexes, there is a tendency that the R1 and R2 increase as the molecular weight is increases. As molecular weight of paramagnetic complex increases, T1 and T2 relaxation times reduce and thus the increase of relaxivity (R1 and R2) Is proportional to molecular weight.

• Proceedings of the Korean Magnetic Resonance Society Conference
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• 2000.08a
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• pp.21-21
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• 2000

• Proceedings of the KSMRM Conference
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• 2001.11a
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• pp.107-107
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• 2001

목적： 초상자성 nano-particle 조영제의 자기이완효과에 관한 out sphere 기전에 기초하여 각각의 자기장의 세기에서 T1/T2 자기이완율을 나타내는 NMRD profile을 수치적으로 simulation 하는 프로그램을 개발하고자 하였다. 대상 및 방법： 초상자성 nano-particle 조영제의 경우 초상자성 물질을 생체적합성 고분자로 표면 coating하기 때문에 상자성 조영제와는 달리 전적으로 "out sphere"기여도만을 고려하였고 또한 초상자성 물질의 경우 자기적 에너지의 크기가 매우 크기 때문에 상자성 조영제의 기전에서 사용되는 "low field"근사를 사용할 수 없으므로 Brillouin 함수로 표현되는 총자화에 대한 표현을 적용하였다. nano-particle내에 포함된 Fe 원자수에 따른 T1 및 T2 NMRD Profile과 온도에 따른 T1 및 T2 NMRD Profile 그리고 초상자성 nano-particle size에 따른 T1 및 T2 NMR Profile을 PC (CPU=800 Mhz, memory=128 MB) 환경하에서 symbolic computation tool 인 MathCad (MathCad, USA)를 사용하여 구현하였다.

• KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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• v.15 no.3
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• pp.83-91
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• 2009

It is very difficult to export the fresh agricultural products to long distance countries such as USA and EU without any damage. Fresh products exporting would overcome very severe conditions such as hot and cold weather changes, heavy vibrations with rolling and pitching during the target distribution period, therefore, the packaging needs the immobility of products in the container and the keeping its quality by packaging materials or methods under any surrounding environments, especially. The physical strength of outer box should be designated according to its own characteristics for agricultural product packaging. Packaging dimension which would be fit to standard pallet is also very important factor to reduce the distribution cost. There have been many agricultural products researches for export packaging to the USA so far. However they have never got desirable results which enough to apply it in real. The main purpose of this research is to develop optimum compressive strength and optimum dimension of corrugated fiberboard box which would be used to USA export packaging of fresh melon as well as Japan.

• Proceedings of the KSMRM Conference
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• 2001.11a
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• pp.117-117
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• 2001

목적： 상자성 자기공명 조영제의 효율을 결정하는 중요 인자중의 하나인 조영제의 rotational correlation time ($\tau$R)을 전자상자성공명 data를 측정하고 이를 정량적으로 분석하여 결정하였다. 대상 및 방법： rotational dynamics가 주로 분자의 크기 및 모양에 의해 결정된다는 점을 이용하여 anisotropic한 (equation omitted) tensor를 가지는 VO$^{2＋}$의 VO(DTPA)시료에 대해 다양한 온도에서 즉 다양한 rotational time에 대해 ESR spectrum을 측정하였다. 측정된 EPR data로부터 (equation omitted) 텐서 그리고 최종적으로 $\tau$R 을 SIMPOW와 EPRLF을 사용하여 계산하였다.