• Title/Summary/Keyword: 상반효과

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Estimation of Combining Abilities for Traits of Mice from Diallel Crosses -I. Estimation of Combining Abilities for Litter Size and Birth Weights of Mice from Diallel Crosses (양면교잡(兩面交雜)에 의(依)한 Mouse 주요(主要) 형질(形質)의 결합능력(結合能力) 추정(推定) -I. 산자수(産仔數) 및 생시체중(生時体重)에 대(對)한 결합능력(結合能力) 추정(推定))

  • Hyun, Byung Hwa;Choi, Kwang Soo
    • Current Research on Agriculture and Life Sciences
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    • v.4
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    • pp.114-118
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    • 1986
  • The study was conducted to find out the gene effects on litter size and birth weights in mice with 362 progenies from full-diallel crosses of four lines of BALB/c, CBA, C3H and C57BL. The progenies were farrowed at the Experimental Animal Farm, College of Agriculture, Kyungpook National University in November, 1984, and data were analyzed into general combining ability, specific combining ability and reciprocal effects with Griffing's model. General combining ability effects estimated in line-crosses were -0.4163~0.3337 for litter size and -0.0356~0.0894 for birth weights. However, no significant differences were observed in general combining ability effects on litter size and birth weights. Specific combining ability effects estimated in line-crosses were -1.0388~1.7913 for litter size and -0.1144~0.1343 for birth weights. However, the specific combining ability effects for litter size and birth weights appeared to be insignificant. The reciprocal effects, which appeared to be significant, were -2.26 from BALB/c ${\times}$ C3H, 1.84 from CBA ${\times}$ C57BL and -1.50 from BALB/c ${\times}$ CBA for litter size. For birth weights, the reciprocal effects were estimated -0.26 from CBA ${\times}$ C57BL, 0.15 from BALB/c ${\times}$ CBA and -0.15 from BALB/c ${\times}$ C57BL.

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The Analysis of the Genetic Variance and Combining Ability in some Quantitative Characters by Daillel Crosses of the Silkworm, Bombyx mori L. (이면교잡에 의한 가잠의 몇가지 실용형질의 유전변이와 조합능력 분석)

  • 장창식;손해룡
    • Journal of Sericultural and Entomological Science
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    • v.27 no.2
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    • pp.7-19
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    • 1985
  • The genetic variances and combinding ability of some useful characters were analyzd on sixty four combinations in the 8$\times$8 diallel cross using the four Japanese races(Jam 107, Jam 113, Jam 117 and Jam 119) and the four Chinese races(Jam 108, Jam 114, Jam 118 and Jam 120). The eight quantitative characters were the total larval stage period(TP), the fifth larval instar period(FP), the female cocoon total weight(FW), the male cocoon total weight(MW), the female cocoon layer weight(FL), the male cocoon layer weight(ML), the female cocoon layer ratio(FR), and the male cocoon layer ratio(MR). The results were as follows: The analysis of the genetic variance and the combining ability in the TP and the FP. In TP and FP, h2N was less than h2B. The GCA, SCA and RCA were at a high significant level. Hl/D and (Hl/D)1/2 ere large. The heterosis were small minus. E and D were large. The r was in the positive direction, because the recessive genes were mainly expressed as a short rearing periods. The regressions of the characters were passed below 0 point, because the characters in the TP and the FP were appeared overdominant. The order of the dominance in the TP of the parents were in the order of Jam 119>Jam 113>Jam 117>Jam 108>Jam 120>Jam 114>Jam 107>Jam 118, and that in the FP of the parents were followed in the orders of Jam 117>Jam 113>Jam 108>Jam 114>Jam 119>Jam 107>Jam 120>Jam 118. The analysis of the genetic variance and the combining ability of the FW and the MW. In the FW and the Mw, h2N was less the h2B. The GCA and SCA were large but RCA was little. Hl/D and (Hl/D)1/2 in the parents were large. Heterosis was large. E was appeared large in the FW, and small in the MW. D was small. The r was of the minus direction, because the dominance genes were less expressed. The regression of the these characters were padded below 0 point, because the characters in FW and MW were appeared overdominant. The orders of the dominance in the FW of the parents were as the order of Jam 107>Jam 108>Jam 119>Jam 113>Jam 114>Jam 120>Jam 117>Jam 118, and in the MW of them in the order of Jam 114>Jam 120>Jam 108>Jam 113>Jam 107>Jam 119>Jam 117>Jam 118. The analysis of the genetic variance and the combining ability of the FL and ML. In the FL and the ML, h2N was less than h2B. GCA and SCA were large. RCA was little. Hl/D and (Hl/D)1/2 ere large. Heterosis was large. The r was in the negative direction, because the dominance genes were less expressed. The regression of the characters of FL and ML were appeared overdominant. The dominance in the FL of parents ere in the order of Jam 120>Jam 114>Jam 119>Jam 119>Jam 118>Jam 107>Jam 117>Jam 113, and the ML of them in the order of Jam 114>Jam 108>Jam 120>Jam 117>Jam 118>Jam 107>Jam 119>Jam 113. The analysis of the genetic variance and combining ability of the FR and the MR. In the FR and the Mr, h2N was less than h2B. GCA was large. The SCA and RCA were little. In the FW, Hl/D was large but (Hl/D)1/2 was a little. In MR, Hl/D and (Hl/D)1/2 both were a littel. Heterosis was a little. E in the FR was in the negative direction, because the dominance genes were less expressed but that in the MR was the positive direction because the recessive genes were mainly expressed. The order of the dominance in the FR of the parents were in the order of Jam 117>Jam 114>Jam 108>Jam 120>Jam 118>Jam 119>Jam 107>Jam 113 and that in the MR these were in the order of Jam 114>Jam 117>Jam 108>Jam 118>Jam 107>Jam 119>Jam 120.

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THE EFFECTS OF SODIUM FLUORIDE ON SQUAMOUS CELL CARCINOMA CELL LINE CULTURED IN VITRO (실험실 내에서 배양된 편평상피암 세포주에 대한 염화불소의 효과)

  • Park, No-Boo
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.2
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    • pp.316-322
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    • 1996
  • The effects of Sodium Fluoride on squamous cell carcinoma cell line(SCC-cells) cultured in vitro have been studied with respect to cytotoxicity and induction of chromosome aberrations. Cytotoxicity of NaF on SCC-cells, as determined by a decrease in colony-forming ability, linearly increased with dose of NaF(150-300 ug/ml) or exposure time (3-24h). SCC-cells treated with 30-60ug/ml NaF for 24h were analyzed for chromosome aberrations. A significant increase in the frequency of chromosome aberration at the chromatid level was induced by NaF in a dose-dependent manner. These results suggest that NaF is a toxic substance which inhibit cell proliferation and causes DNA damage in SCC-cells cultured in Vitro.

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Effects of categorization on linguistic spatial representation and non-linguistic spatial representation (언어적 공간표상과 비언어적 공간표상에서의 범주화의 효과)

  • 서원식;한광희
    • Proceedings of the Korean Society for Cognitive Science Conference
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    • 2002.05a
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    • pp.119-124
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    • 2002
  • 공간적 관계정보(spatial relation)가 언어적 표상시스템과 비언어적 표상시스템에서 어떻게달라지는가를 범주화 모델의 원형이론 모델을 적용하여 알아보고자 하였다. 이전의 연구들에 따르면 공간적 관계정보에 대한 프로토타입이 언어적 범주와 비언어적 범주에서 다르다는 연구 결과(Crawford 등 2000, Huttenlocher 등 1991)와 동일하다. (Hayward & Tarr 1995)는 상반된 연구 결과가 제기되고 있다. 하지만 이전 연구들에서의 문제점은 언어/비언어 표상체계 간의 편향을 통제하지 못했기 때문에 과제에 따라 서로 다른 결과가 나온 것이라고 볼 수 있다 본 연구에서는 두 대상간의 관계정보를 문장으로 제시한 조건, 그림으로 제시한 조건, 그리고 두 조건을 혼합한 조건을 사용하여 편향에 의한 효과를 제거하고자 하였다. 실험은 각 조건에 따라 짝으로 구성된 자극을 학습한 후 검사자극을 공간적 관계정보를 다양하게 하여 학습자극과 동일한지 아닌지를 판단하게 하였다. 실험결과 관계정보를 언어적으로 제시한 조건과 비언어적으로 제시한 조건간에 대상의 위치에 따른 반응시간의 경향성에서 차이가 없었으며, 대상이 단어인지 그림인지에 따라서 반응시간에서 통계적으로 차이가 나타났다. 그리고 두 표상체계에서 공간적 관계에 대한 프로토타입을 분석한 결과 수직축을 중심으로 전형성 효과가 나타나는 것을 알 수 있었다.

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The Dynamic Effect of Highspeed Trains on Railway Bridges (고속철도 차량의 주행이 교량에 미치는 충격효과)

  • Yu, Chul Soo;Kang, Young Jong;Kim, Jong Heun;Kweon, Jae Hyun
    • Journal of Korean Society of Steel Construction
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    • v.10 no.2 s.35
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    • pp.187-199
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    • 1998
  • The highspeed railway bridge which support continuous and high moving mass evalute the dynamic state and make the displacement of the bridge makes more or less, but up to this time the bridges are designed by the static design concept. for example when we design bridge we use impact factor, which only times the static load makes dynamic load. But becouse it simples. it can't express all of the effects. And so, in this report we study the modeling method of the moving mass and the dynamic factor.

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EFFECT OF KOREAN RED GINSENG POWDER (GP), ADMINISTERED ORALLY, ON BLOOD PRESSURE IN HYPERTENSIVE RATS (홍삼분말이 고혈압 쥐에 미치는 영향)

  • Sokabe Hirofumi;Kishi Koichiro;Watanabe Takushi X.
    • Proceedings of the Ginseng society Conference
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    • 1984.09a
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    • pp.127-132
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    • 1984
  • 이미 발표된, 혈압에 미치는 인삼의 효과에 관한 연구들의 보고는 서로 상반된 견해들이 많이 있다. 인삼에는 혈압상승작용과 혈압을 내려주는 효과가 모두 있다고 보고하였다. 본 저자들은 고혈압 쥐에 미치는 인삼의 급${\cdot}$만성효과를 연구하기 위해 일련의 2가지 실험을 하였으며, 실험재료로 사용한 홍삼은 일한홍삼주식회사에서 구입하였다. (실험 1) 홍삼분말을 일반 쥐사료에 혼합하여 (5g/kg), 임의로 사료를 섭취하게 하여 11주간 쥐를 사육하였으며, 하루에 섭취한 인삼의 양은 체중 kg당 $250{\~}750$mg이었다. 홍삼분말의 투여는 DON쥐, SHR쥐, 그리고 한개의 신장을 협자시킨 고혈압 쥐의 경우 혈압에 영향을 미치지 않았다. 홍삼분말의 투여는 DOC 쥐에 있어 혈압을 약간 상승시켰다. (실험 2) 홍삼분말을 체중 kg당 350mg씩 경구투여한 후 복대동맥에 카뉼제를 삽입하여 혈압을 24시간 직접 측정하였다. 그 결과 DOC쥐와 SHRSP쥐에 있어 혈압에 영향이 없었다. 이 실험에서는 마취를 시키지 않았으며, 자유로이 풀어 놓았다. 실험 1과 같이 매일 체중 kg당 $300{\~}500$mg씩 11주간 홍삼분말을 만성적으로 투여하였을 때, SHRSP쥐의 혈압에 영향이 없었다. DOC 고혈압 쥐의 경우 약간의 혈압 강하가 있었으며, DOC 고혈압의 정도는 (실험 2)에서 약간 낮았다.

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Numerical Study on the Effects of Geosynthetic Reinforcement on the Pile-supported Embankment (수치해석을 통한 성토지지말뚝에 대한 토목섬유 보강 효과 분석)

  • Lee, Su-Hyung
    • Journal of the Korean Society for Railway
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    • v.12 no.2
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    • pp.276-284
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    • 2009
  • Recently pile-supported embankments have emerged as an optimum method when the rapid construction and strict deformation of structures are required on soft soils. Especially geosynthetic-reinforced and pile-supported (GRPS) embankments are used worldwide as they can provide economic and effective solutions. However the load transfer mechanism in GRPS embankments is very complex, and not yet fully understood. Particularly the purpose and effect of geosynthetic inclusion are ambiguous and considered as an auxiliary measure assisting the arching effect of piles. Numerical parametric study using 3D finite element method has been conducted to investigate the effect of geosynthetic reinforcement on the load transfer mechanism of GRPS embankments. Numerical results suggested that as more stiffer geosynthetic is included, arching effect decreases considerably and the load concentration to the piles mostly caused by tension effect of geosynthetic. This finding is contradictory to the common understanding that geosynthetic inclusion only enhance the efficiency of load transfer. Consequently the design parameters determined from the numerical analyses are compared with those of three existing design methods. The problems of the existing methods are discussed.

3D Finite Element Analysis of Rock Behavior with Bench Length and Gther Design Parameters of Tunnel (터널의 벤치길이를 중심으로 한 설계변수에 따른 암반거동의 3차원 수치해석)

  • 강준호;정직한;이정인
    • Tunnel and Underground Space
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    • v.11 no.1
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    • pp.30-35
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    • 2001
  • Focusing on the bench length, this paper presents the results of 3-dimensional elafto-plastic FE Analysis un tunnels of full face, mini-bench and short bench excavated in weathered rock. Influences of unsupported span, horizontal to vertical stress ratio, thickness of shotcrete on the behavior of rock and support were a1so studied. Results showed that displacements of mini-bench tunnels responded more sensitively to bench lengths than those of short bench. The effects of bench excavation on upper half displacement increased with longer unsupported span. Horizontal to vertical stress ratio showed a greater influence on displacement and preceding displacement ratio or sidewall rather than those of crown and invert.

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Effect of Electron Correlation on Radical Stabilization Energies (라디칼 안정화에너지에 미치는 전자 Correlation 효과)

  • Ikchoon Lee;Bon-Su Lee;Chang Hyun Song
    • Journal of the Korean Chemical Society
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    • v.27 no.5
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    • pp.320-329
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    • 1983
  • Effect of alkyl substitution on stabilization of $\alpha$-aminomethyl radicals, $CH_2NH_2$, has been investigated using MINDO/3-RHF method. Stabilization energies obtained from total energy of radicals indicated that the alkyl substitution decreases radical stability, which is in agreement with the ab initio MO results of Goddard but is contrary to trend shown by experimental results. It was also found that conformations of radicals were different from ab initio results. When, however, approximate account of electron correlation was made in the estimation of stabilization energies of radicals by assuming a proportionality between coulomb correlation and one center exchange integral, the order of radical stability was shown to agree to that found experimentally. It was therefore concluded that the main cause of discrepancy between theoretical and experimental order of stability of alkylsubstituted radicals is the failure of accounting electron correlation energies in the theoretical estimation.

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Adaptive Load Balancing Algorithm of Ethereum Shard Using Bargaining Solution (협상 해법을 이용한 이더리움 샤드 부하 균형 알고리즘)

  • Baek, Dong Hwan;Kim, Sung Wook
    • KIPS Transactions on Computer and Communication Systems
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    • v.10 no.4
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    • pp.93-100
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    • 2021
  • The Ethereum shard system for solving the scalability problem of the blockchain has a load balancing issue, which is modeled as a graph partitioning problem. In this paper, we propose an adaptive online weighted graph partitioning algorithm that can negotiate between two utility of the shard system using the game theory's bargaining solution. The bargaining solution is an axiomatic solution that can fairly determine the points of conflict of utility. The proposed algorithm was improved to apply the existing online graph partitioning algorithm to the weighted graph, and load balancing was performed efficiently through the design considering the situation of the sharding system using the extension of Nash bargaining solution, which is extended to apply solution to non-convex feasible set of bargaining problem. As a result of the experiment, it showed up to 37% better performance than typical load balancing algorithm of shard system.