• Analytical Science and Technology
• /
• v.35 no.3
• /
• pp.136-142
• /
• 2022

According to media reports, the carcasses of euthanized abandoned dogs were processed at high temperature and pressure to make powder, and then used as feed materials (meat and bone meal), raising the possibility of residuals in the feed of the anesthetic ketamine and dexmedetomidine used for euthanasia. Therefore, a simultaneous analysis method using QuEChERS combined with high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry was developed for rapid residue analysis. The method developed in this study exhibited linearity of 0.999 and higher. Selectivity was evaluated by analyzing blank and spiked samples at the limit of quantification. The MRM chromatograms of blank samples were compared with those of spiked samples with the analyte, and there were no interferences at the respective retention times of ketamine and dexmedetomidine. The detection and quantitation limits of the instrument were 0.6 ㎍/L and 2 ㎍/L, respectively. The limit of quantitation for the method was 10 ㎍/kg. The results of the recovery test on meat and bone meal, meat meal, and pet food showed ketamine in the range of 80.48-98.63 % with less than 5.00 % RSD, and dexmedetomidine in the range of 72.75-93.00 % with less than 4.83 % RSD. As a result of collecting and analyzing six feeds, such as meat and bone meal, prepared at the time the raw material was distributed, 10.8 ㎍/kg of ketamine was detected in one sample of meat and bone meal, while dexmedetomidine was found to have a concentration below the limit of quantitation. It was confirmed that the detected sample was distributed before the safety issue was known, and thereafter, all the meat and bone meal made with the carcasses of euthanized abandoned dogs was recalled and completely discarded. To ensure the safety of the meat and bone meal, 32 samples of the meat and bone meal as well as compound feed were collected, and additional residue investigations were conducted for ketamine and dexmedetomidine. As a result of the analysis, no component was detected. However, through this investigation, it was confirmed that some animal drugs, such as anesthetics, can remain without decomposition even at high temperature and pressure; therefore, there is a need for further investigation of other potentially hazardous substances not controlled in the feed.

• Tunnel and Underground Space
• /
• v.22 no.5
• /
• pp.346-353
• /
• 2012

Multi-specimen uniaxial compression test has been carried out in order to find the method to determine the five independent elastic constants from a single standard specimen of a transversely isotropic rock. Total 35 specimens of 7 different angles from a large block of rhyolite presenting the flow structure obviously are used in tests. This second report is to focus on the statistical evaluation of measured strains and analyzed elastic constants. And the determination of their true or near-true values is discussed. As the result of RSD analysis, it turns out that the reliability of measured strains is sufficiently obtained and Saint-Venant approximation is well applicable except 15 degree angled specimen in tests. RSD is decreasing on the increase of the angle of anisotropy. This tendency may be caused not only by the decreasing of the deviation of measured strains, but also by the better applicability of Saint-Venant approximation on the increase of angle. It can be concluded that the analyzed values are considered the near-true ones of five independent constants on the high reliability. But the variation of the apparent Young's modulus expected by these values is not proved to match the measured tendency. It is inferred that the factor to decrease the apparent Young's modulus and/or to increase the shear strain, is present in the test or in the nature of the anisotropy in consideration of this inconsistency.

• The Journal of the Petrological Society of Korea
• /
• v.24 no.2
• /
• pp.141-147
• /
• 2015

Using laser-ablation inductively coupled plasma mass spectrometry (LA-ICP-MS), we evaluated the reliability of trace element abundance data measured from the silicate rock references of JR-3, JG-3, JGb-1 and JB-1b using glass discs made by alkali fusion. For 28 elements including rare earth elements, relative standard deviations (RSD) are better than 7% in case when the concentrations of the elements in the rock samples are greater than 10 ppm. However, RSD shows somewhat increased values for the concentrations less than 10 ppm, but never exceeds 25%. Compared with previously reported averages of the compiled abundance data, our data display satisfactory results for the most cases with differences less than 10%. We suggest that LA-ICP-MS analysis using fused glass beads is a reliable, precise and time-saving method of trace element analysis for the silicate rocks spanning from mafic to felsic compositions.

• Analytical Science and Technology
• /
• v.12 no.1
• /
• pp.28-33
• /
• 1999

Glutathione(GSH) in biological samples was determined by high performance liquid chromatographic(HPLC) method with fluorescence detector(FLD) after monobromobimane(MBB) or 4-fluoro-7-sulfobenzofurazan(SBD-F) derivatization. The detection limit of $0.03{\mu}g/mL$ was obtained after MBB derivatization, derivative of MBB was about 200 times more sensitive than that of SBD-F. N-acetylcysteine was used as internal standard and tetrabutylammonium ion as counter ion for better separation. The determination by ion-pairing chromatography after MBB derivatization was characterized by linearity in the range between $0.08{\sim}8.33{\mu}g/mL$ with a good correlation coefficient of 0.998. By precision test appeared relative standard deviation at less than 5% at three different concentrations. This method can be used for the analysis of GSH in plasma and tissue.

• Journal of the Korean Chemical Society
• /
• v.43 no.6
• /
• pp.644-650
• /
• 1999

Trace amount of cobalt in water samples was preconcentrated continuously with an organic precipitant and determined by flame atomic absorption spectrometry. The flow injection technique was used to preconcentrate cobalt by on-line direct precipitation with 1-nitroso-2-naphthol. The precipitation was dissolved with methyl isobutyl ketone (MlBK) and was sent to the flame. The optimum conditions for cobalt determination were determined and used to analyze Co samples. For 1.0 mL of sample, the enrichment factor was 13 and the sample throughput was about lO per hour for 0.5 ppm Co solution. The enrichment factor was increased to 68 fold for 10.0 mL. A semi-reference biologicaI sample was prepared and analyzed. The result was in good agreement with the expected value with RSD of 4%.

• Analytical Science and Technology
• /
• v.8 no.1
• /
• pp.9-16
• /
• 1995

The low concentration of cadmium in the whole-blood was determined by graphite furnace atomic absorption spectrometry(GFAAS) after the sample was diluted five-fold by 1% Triton X-100, 2% $(NH_4)_2HPO_4$ as matrix modifier and pyrocoated graphite tube with L'vov platform was tried remove the interferences of blood matrix and reduce the loss of volatility of cadmium at higher ashing temperature($600^{\circ}C$). The criteria for evaluating the accuracy and precision of this analysis was confirmed by analysis of interlaboratory comparison(Japan) and NIST SRM No. 909(Cd in Serum). The limit of the determination for cadium was 0.1ng/ml and the relative standard deviation(RSD) at 1.0ng/ml level was about 10% for the GFAAS.

• Analytical Science and Technology
• /
• v.16 no.3
• /
• pp.191-197
• /
• 2003

Two methods, IDMS (Isotope Dilution Mass Spectrometry) and controlled potential coulometry are compared by the determination of Pu for the NBL, CRM No.122, $PuO_2$. The recovery of Pu was found to be $1.002176{\pm}0.000452$ within the relative standard deviation of 0.045% (95% conf. level) although a small size of sample ($0.9{\mu}g$-Pu) was used in IDMS. The recovery using controlled potential coulometry were obtained in the range of 0.9923~0.9960. The analytical results of IDMS and controlled potential coulometry were good agreement within 0.6~1%. Base on these experiment results, The plutonium in HANARO irradiated fuel rod that separated portion of top, middle, and bottom were determined. The measured values of Pu are 1.155 mg, 2.483 mg and 1.920 mg in one gram of sample(fuel+clad), respectively.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.20 no.2
• /
• pp.112-121
• /
• 1984

This paper is compared the simulation tables by the general propagation velocity and the calculated propagation velocities with distances and times to take to be transmitted Loran C wave from master station to slave stations, with Loran C tables, and compared the accuracy of position fixes by the simulation to them by Loran C table with the time differences of 9970 chain to be measured in the south coast of Korea, and by the simulation with the time differences of 5970 chain to be measured at definite position to them. The results obtained are as follows; 1. the simulation tables by the calculated propagation velocities is nearer to Loran C tables than it by the general propagation velocity. 2. The ranges of total errors of the simulation positions by the general propagation velocity and the calculated propagation velocities to the position fixies of Loran C table with the time differences of 9970 chain to be measured in the south coast of Korea are 0.2-0.7 miles, 0.01-0.1 miles, and the mean values of them are 0.46 miles and standard deviations of time are 0.1 miles, 0.03 miles respectively. 3. Mean value of total errors of the simulation position by the calculated propagation velocities to the definite position with the time difference of 5970 chain is 0.2miles and is reduced 0.1-0.2 miles than it by the general propagation velocity.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2015.05a
• /
• pp.441-441
• /
• 2015

북한의 수자원 현황을 분석하고 미래를 전망하는 일은 수자원 분야 전문가들의 공통된 관심사 중 하나이다. 그러나 많은 노력에도 불구하고 제한된 자료로 인해 이에 대한 체계적인 성과가 구축되지 못한 것이 사실이다(안재현 등, 2010). 북한 수자원 현황과 관련해서 1994년 한국수자원공사의"북한 수자원 현황 및 개발 동향"에 대한 연구와 1996년 한국과학기술단체총연합회의"남북한 수자원 비교평가 연구"가 수행된 바 있다. 본 연구에서는 2012년 7월 북한의 홍수피해에 대하여 북한지역의 빈약한 강우량 정보를 활용하여 위성으로부터 유도된 강우자료를 보정하여 북한지역의 홍수량을 산정하는데 활용할 수 있는 시계열 자료를 생성하는 것을 목적으로 하였다. 2012년 북한 홍수피해는 조선 중앙통신 보도에 의하면 6월 말부터 7월말까지 169명 사망, 400여명 실중, 144명 상해의 인명피해와 평안남북도, 자강도, 함경남북도 등 4만 3770여 가구가 침수되었으며, 농경지 피해는 6만 5280정보가 유실, 매몰, 침수(평안북도 2만 3400정보, 평안남도 2만 1900정보, 함경남도 5679정보, 함경북도 7220정보)의 피해를 입은 것으로 보도하고 있다(http://www.hani.co.kr/arti/politics/defense/545795.html). 한편, 북한의 기상수문국 통보에 의하면 2012년 장마가 시작된 이후 20일 동인 평균 강우량의 2배 가까운 비가 내렸으며, 특히 7월 19일 오후 9시부터 21일 오후 3시 사이 자강도 동신군에 413mm, 송원군에 383mm, 희천시에 322mm, 평안북도 태천군에 380mm, 향산군에 312mm, 동창군에 304mm의 폭우가 쏟아졌다고 조선중앙통신은 덧붙였다. 본 연구에서는 위성으로부터 유도된 강수자료 중 GSMaP_NRT자료를 활용하여 북한의 기상수문국에서 통보한 같이 기간의 강수량 자료를 분석한 결과 자강도 동신군 지역의 경우 총강우는 208.8mm로 분석되었으며, 평균강우는 9.49mm, 최대강우강도는 17.7mm/hr로 분석되었다. 두 자료의 총강우량에 대한 상대오차는 약 49.5% 정도의 오차가 있는 것으로 분석되었다. 위성강우 보정 방법으로 Immerzeel(2001) 등은 위성으로 관측된 시계열 자료와 지상계측된 시계열 자료를 분석하여 두 자료간의 평균과 표준편차를 이용하여 평균 및 표준편차 계수를 산정하여 위성자료에 대한 보정강우를 생성하는 방법을 제시한 바 있다. 본 연구에서는 위성으로부터 유도된 강우량 자료는 시계열 자료이나 지점계측 강우는 총강우만 존재하여 총강우에 대한 시계열 자료를 위성강수자료를 무차원화하여 지점계측의 위성 보정강우를 생성하였다.

• Analytical Science and Technology
• /
• v.17 no.5
• /
• pp.381-387
• /
• 2004

To characterize chemically a spent pressurized water reactor (PWR) fuel, an analytical method for trace amounts of tritium ($^3H$) in it has been established. Considering the effective management of radioactive wastes generated through the whole experimental process and the radiological safety for analysts, a separation condition under which $^{14}C$ and $^3H$ can be sequentially recovered from a single fuel sample was optimized using simulated spent PWR fuel dissolved solutions. $^{14}CO_2$ evolved during dissolution of the spent PWR fuels with nitric acid was trapped in an aliquot of 1.5 M NaOH. $^{129}I_2$ which was volatilized along with $^{14}CO_2$ was removed using a silver nitrate-impregnated silica gel absorbent. $^3H$ remaining in the fuel dissolved solution as $^3H_2O$ was selectively recovered by distillation. Its recovery yield was 97.9% with a relative standard deviation of 0.9% (n=3). $^3H$ in a spent PWR fuel with burnup value of 37,000 MWd/MtU was analyzed, reliability of this analytical method being evaluated by standard addition method.