• Title/Summary/Keyword: 산학협력센터

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Gastroprotective Activity of Curcumae Longae Rhizoma against Gastric Ulcer in Mice (위궤양 유발 마우스모델에서 강황(薑黃) 추출물의 위 보호 효과)

  • Oh, Min Hyuck;Kim, Min Ju;Shin, Mi-Rae;Park, Hae-Jin;Seo, Bu-Il;Roh, Seong-Soo
    • The Korea Journal of Herbology
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    • v.35 no.3
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    • pp.17-24
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    • 2020
  • Objectives : The objective of this study was to evaluate the gastric protective effect of Curcuma Longae Rhizoma (CLR) in 150 mM HCl/60% ethanol induced gastric ulcer (GU) in mice. Methods : Forty ICR mice were divided into five groups (n=8/Group): Nor group; Normal, Veh group; GU control, SC group; GU + sucralfate 10 mg/kg, CL; GU + CLR 30% ethanol extract 100 mg/kg, CH group; GU + CLR 30% ethanol extract 200 mg/kg. Then, mice were orally administered with 150 mM HCl/60% ethanol and caused GU. After 1 hr, mice were sacrificed, and blood and stomach tissue were collected. Results : CLR showed significance scavenging effects in 1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azinobis-3-ethyl-benzothiazoline-6-sulfonic acid (ABTS) radical scavenging activities (DPPH IC50; 78.18 ± 0.60 ㎍/㎖, ABTS IC50; 55.91 ± 1.86 ㎍/㎖). CLR significance reduce inflammatory-related factors such as cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNF-α), interleukin 1 beta (IL-1β), and interleukin-6 (IL-6) via nuclear factor kappa B (NF-κB) inactivation. In addition, the activation of nuclear factor erythroid2-related factor 2 (Nrf2) significantly led to up-regulation of anti-oxidant enzymes including factors heme oxygenase-1 (HO-1), super oxide dismutase (SOD), and glutathione peroxidase-1/2 (GPx-1/2). Conclusions : Our discovery provides that CLR possesses anti-oxidant and anti-inflammatory effects. Hence, CLR may ameliorate the development of gastric ulcer though the inhibition of NF-κB inflammatory pathway and the elevation of Nrf2 anti-oxidant pathway.

Trophic Transfer of Disinfectant Chemical in Aquatic Ecosystem (소독살균제 기인 화학물질의 수생태계 내 생물 전이 특성 연구)

  • Ha-Eun Cho;Dokyun Kim;Eun-Ji Won;Hyeong-Wook Jo;Kwang-Guk An;Kyung-Hoon Shin
    • Korean Journal of Ecology and Environment
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    • v.55 no.4
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    • pp.376-389
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    • 2022
  • Despite the consumption of disinfectants have been increased by COVID-19 pandemic, the fate of the chemicals in aquatic food webs are still unclear. In order to understand the trophic transfer of the chemicals, the concentration of disinfectants including six benzalkonium chloride (BACs) and five didecyldimethylammonium chlorides(DDACs) were measured at the Geum (2020), Han (2021), and Yeongsan River (2021), before and after rainfall. The highest concentration of ∑BACs (mainly C12 and C14) and ∑DDACs (mainly C10 and C14) were observed in the Han River, followed by Yeongsan River, Geum River Estuary, and Gapcheon. After rainfalls, both concentration and detection frequency were decreased in all sites. Although the BAC and DDAC seems to be accumulated in organisms, they were bio-diluted rather than magnified in the aquatic food web with the biomagnification factor(BMF) of less than 1, trophic magnification slope (TMS) from -0.236 to 0.001, and trophic magnification factor(TMF) from 0.85 to 1.01.

Influence of Alkali Activator Type and Amount of Addition on CO2 Uptake of GGBFS Geopolymer Pastes Containing Zeolite (알칼리계 활성화제의 종류 및 첨가량이 고로슬래그-제올라이트 지오폴리머 페이스트의 탄소포집에 미치는 영향에 관한 연구)

  • Jang-Hyun Park;Hyo-Min Kim
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.11 no.2
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    • pp.112-119
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    • 2023
  • In this study, the variations in CO2 uptake according to the type and amount of alkali-based activator (Ca(OH)2, CSA) of geopolymer paste were evaluated. As the amount of activator added to the geopolymer paste increased, the fluidity of the paste is decreased and the compressive strength increased. According to the type of activator, it was confirmed that the addition of Ca(OH)2 had a greater effect on improving the compressive strength than CSA. As a result of changes in chemical properties according to carbonation curing, the amount of C-S-H and C-A-S-H gels produced before carbonation increased as the amount of activator increased, and amount of CaCO3 produced after carbonation increased. The reactivity of the blast furnace slag and zeolite increased due to the addition of the activator, and the reactivity tended to increase as the amount of addition increased. As a result of CO2 uptake, 10.3 wt% when Ca(OH)2 10 % was added and 8.77 wt% when CSA 10 % was added was confirmed. It increased by 421 % and 388 % respectively, compared to the case where no activator was added.

KoFlux's Progress: Background, Status and Direction (KoFlux 역정: 배경, 현황 및 향방)

  • Kwon, Hyo-Jung;Kim, Joon
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.12 no.4
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    • pp.241-263
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    • 2010
  • KoFlux is a Korean network of micrometeorological tower sites that use eddy covariance methods to monitor the cycles of energy, water, and carbon dioxide between the atmosphere and the key terrestrial ecosystems in Korea. KoFlux embraces the mission of AsiaFlux, i.e. to bring Asia's key ecosystems under observation to ensure quality and sustainability of life on earth. The main purposes of KoFlux are to provide (1) an infrastructure to monitor, compile, archive and distribute data for the science community and (2) a forum and short courses for the application and distribution of knowledge and data between scientists including practitioners. The KoFlux community pursues the vision of AsiaFlux, i.e., "thinking community, learning frontiers" by creating information and knowledge of ecosystem science on carbon, water and energy exchanges in key terrestrial ecosystems in Asia, by promoting multidisciplinary cooperations and integration of scientific researches and practices, and by providing the local communities with sustainable ecosystem services. Currently, KoFlux has seven sites in key terrestrial ecosystems (i.e., five sites in Korea and two sites in the Arctic and Antarctic). KoFlux has systemized a standardized data processing based on scrutiny of the data observed from these ecosystems and synthesized the processed data for constructing database for further uses with open access. Through publications, workshops, and training courses on a regular basis, KoFlux has provided an agora for building networks, exchanging information among flux measurement and modelling experts, and educating scientists in flux measurement and data analysis. Despite such persistent initiatives, the collaborative networking is still limited within the KoFlux community. In order to break the walls between different disciplines and boost up partnership and ownership of the network, KoFlux will be housed in the National Center for Agro-Meteorology (NCAM) at Seoul National University in 2011 and provide several core services of NCAM. Such concerted efforts will facilitate the augmentation of the current monitoring network, the education of the next-generation scientists, and the provision of sustainable ecosystem services to our society.

Characteristics of Vegetation Structure of Burned Area in Mt. Geombong, Samcheok-si, Kangwon-do (강원도 삼척 검봉산 일대 산불 피해복원지 식생 구조 특성)

  • Sung, Jung Won;Shim, Yun Jin;Lee, Kyeong Cheol;Kweon, Hyeong keun;Kang, Won Seok;Chung, You Kyung;Lee, Chae Rim;Byun, Se Min
    • Journal of Practical Agriculture & Fisheries Research
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    • v.24 no.3
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    • pp.15-24
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    • 2022
  • In 2000, a total of 23,794ha of forest was lost due to the East Coast forest fire, and about 70% of the damaged area was concentrated in Samcheok. In 2001, artificial restoration and natural restoration were implemented in the damaged area. This study was conducted to understand the current vegetation structure 21 years after the restoration of forest fire damage in the Samcheok, Gumbong Mountain area. As a result of classifying the vegetation community, it was divided into three communities: Quercus variabilis-Pinus densiflora community, Pinus densiflora-Quercus mongolica community, and Pinus thunbergii community. Quercus variabilis, Pinus densiflora, and Pinus thunbergii planted in the artificial restoration site were found to continue to grow as dominant species in the local vegetation after restoration. As for the species diversity index of the community, the Quercus variabilis-Pinus densiflora community dominated by deciduous broad-leaf trees showed the highest, and the coniferous forest Pinus thunbergii community showed the lowest. Vegetation in areas affected by forest fires is greatly affected by reforestation tree species, and 21 years later, it has shown a tendency to recover to the forest type before forest fire. In order to establish DataBase for effective restoration and to prepare monitoring data, it is necessary to construct data through continuous vegetation survey on the areas affected by forest fires.