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A Twenty-Eight Days Inhalation Toxicity Study of N-decane in Sprague Dawley Rats (SD흰쥐를 이용한 n-decane의 28일 반복흡입독성연구)

  • Rim Kyung Taek;Kim Hyeon Young;Song Kyung Seuk;Chung Yong Hyun;Chang Hee Kyung;Han Jeong Hee;Lee Sung Bae;Chun Yoon Seok;Lee Yong Mook;Yu Il Je
    • Environmental Analysis Health and Toxicology
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    • v.19 no.4
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    • pp.345-352
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    • 2004
  • N-decane은 지방족탄화수소로 다른 탄환수소들과 같이 혼합된 형태로 존재하며 페인트 제거제나 드라이 크리닝 제품에 사용된다. 최근의 본 연구팀이 실시한 전자산업계의 MSDS 신뢰성조사 결과에 따르면 세정제의 사용 경향은 과거의 방향족 탄화수소나 CFC. HCFC에서 $C_{10}$이상의 지방족탄화수소 물질로 변화되고 있는 경향을 보여주었다. Stoddard solvent나 나프타 같은 탄화수소 혼합물에 대한 작업 환경노출기준은 설정되어있지만 n-decane에 대해서는 제한적인 독성자료 밖에 없으며 작업환경노출기준은 설정되어 있지 않다. 따라서 작업환경에 대한 적절한 관리기준제시와 독성학적 자료를 제공하기 위해 n-decane을 28일 반복 흡입독성시험을 실시하였다. 6주령 흰쥐로 체중이 229$\pm$10g되는 숫컷과 165$\pm$7g되는 암컷 흰쥐를 4개 용량군 즉 대조군, 저농도군(50ppm), 중농도군(200ppm), 고농도군(800ppm) (각군당 10마리)으로 설정하여 하루 6시간, 주5일로 4주간 흡입쳄버에서 노출시켰다. 28일간 노출 후 n-decane의 노출용량에 따른 암수의 체중에는 유의한 변화가 없었으며 유의한 혈액학적 생화학적 변화도 발견되지 않았다. 고농도로 노출된 수컷 몇 마리에서 고환 세정관에서의 공포화(vacuolization)가 발견되었으나, 간신장, 비장, 폐, 부신, 심장, 뇌 등 다른 장기에 대한 조직병리학적 검사에서는 뚜렷한 조직병리학적인 변화를 발견할 수 없었다.

Occurrence and Ecological Characteristics of Chiasmia cinerearia(Bremer et Grey)(Lepidoptera: Geometridae) Attacking Sophora japonica (회화나무(Sophora japonica)를 가해하는 줄마디가지나방(Chiasmia cinerearia (Bremer et Grey))의 발생 및 생태적 특성)

  • Kwon, Gun-Hyung;Lee, Min-Seop;Eom, Hoon-Sik;Kim, Yong-Hun;Kwon, Young-Dae
    • Korean journal of applied entomology
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    • v.55 no.1
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    • pp.67-71
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    • 2016
  • Chiasmia cinerearia (Bremer et Grey) belonging to the subfamily Ennominae(Lepidoptera: Geometridae) is a new forestry pest attacking to Sophora japonica in Gyeonggi province. Chiasmia cinerearia oviposited about 250~300 eggs per female on leaves. Larva had five instar stages. Adults emerged twice a year in early May and late July. The period of one generation was about 48 days. Body length of larvae was 25~30 mm and body color was light green with dark yellow lateral lines in abdomen. The wingspan of adults was 30 to 35 mm in length. The color of forewings was greyish brown with quadrilateral patterns on outer lines.

Relationships Between Risk Factors and R&D Output: Approach to New Product Development process (위험요인과 R&D성과 간의 관계: 신제품개발단계별 접근)

  • Han, Sang Rog;Cho, Kuen Tae
    • Journal of Technology Innovation
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    • v.21 no.1
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    • pp.165-198
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    • 2013
  • The purpose of the study is to identify risk factors and analyze risk impacts to increase R&D outcome by taking into consideration the activities undertaken in each phase of New Product Development(NPD) process. The paper builds on survey research that has been developed new IT products within the past 5 years at SAMSUNG and LG subsidiaries in the Republic of Korea. This study identified risk factors in accordance with NPD process and evaluated the identified risk factors with survey questionnaires. To analyze the risk impacts were used to perform a logistic regression analysis based on R&D output. The impact of risk factors were higher for the low-output group. High-output group took a risk into consideration unique undertakings in project management and managed risk factors effectively in order to increase R&D output. Consequently, with the aim of improving output of R&D, a risk management is necessary to identify the risk factors for each phase of NPD and focus on managing risk factors with great effect.

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Application of cover material for reduction of sediment discharge from sloping upland plots (경사밭에서 발생하는 토양유실량 저감을 위한 지표피복재 적용)

  • Kang, Jong-Cheon;Shin, Min-Hwan;Park, Woon-Ji;Won, Chul-Hee;Choi, Joong-Dae
    • Proceedings of the Korea Water Resources Association Conference
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    • 2011.05a
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    • pp.336-336
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    • 2011
  • 본 연구에서는 강우시 경사지 밭에서 발생하는 토양유실량을 저감하기 위하여 지표피복재의 유무와 강우강도를 달리하여 실외인공강우 실험을 통하여 평가하였다. 인공강우 실험은 경사도 28%와 각 시험포는 $5\times30m$의 크기로 strawmat+PAM+sawdust, control(bare), strawmat+PAM, strawmat+PAM+rice husks를 4개 조성하고, 각 시험포는 하단부에 강우유출수를 채취할 수 있는 설비(flume)를 설치하였다. 대조구 실험을 위하여 각 시험포에서 발생하는 직접유출량과 유사량을 비교 분석하였다. 시험포의 토양은 양질사토로 일반 고랭지 밭의 흙과 동일한 성질을 가지고 있는 토양을 사용하였고, 지표 피복처리는 straw mat, saw dust, rice husk 그리고 PAM 등 4개의 재료를 사용하였다. 인공강우 실험은 1차 10월 18일, 2차 10월 24일, 3차 10월 30일, 4차 11월 7일로 총 21일간 각각 약 1주일의 간격을 두고 실시하였으며 인공강우 시험기의 강우강도는 각 31.1 ~ 44.4 mm/hr로 모의하였다. 연구결과 시험포에서 발생한 유출량은 지표피복을 하지 않은 대조구 시험포보다 지표를 피복한 시험포에서 약 15.7 ~ 19%의 감소한 것으로 나타났다. 유사량은 대조구 시험포보다 약 93.1 ~ 99.3% 감소한 것으로 나타났으며, 유출량과 유사량은 straw mat+PAM+sawdust와 straw mat+PAM+rice husk를 적용한 시험포에서 저감효과가 큰 것으로 나타났다. 이와 같이 지표피복처리는 강우가 발생하였을 때 강우타격력의 감소와 유출수의 유속감소 그리고 침투능을 증가하는 역할을 하여 경사지, 농경지 및 공사현장에서 토양 유실을 저감하며, 하천이나 강으로 유입되는 탁수량의 저감에 큰 효과가 있을 것으로 판단된다.

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A Study on Puberty and Sex Hormone Levels In Korean Native and Charolais x Native Crossberd Heifers (한우와 샤로레 교잡종 빈우의 성성숙과 성호르몬 수준 변화에 관한 연구)

  • Chung Y. C.;Kim C. K.;Lee K. S.
    • Journal of the korean veterinary medical association
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    • v.18 no.7
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    • pp.64-73
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    • 1982
  • This experiment was conducted to determine the age and weight at first estrus and to characterize the serum LH, FSH, prolactin, progesterone and estradiol during growth and puberty in Korean native heifers and Charolais x native crossbred heifers. Four pu

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Whole Crop Silage Making of Barley Produced in Paddy Find of Central and Northern Region (중북부지역 답리작 보리담근먹이 조제이용 연구)

  • Kim, W.H.;Shin, J.S.;Seo, S.;Chung, E.E.;Rim, Y.C.;Park, G.J.;Choi, S.H.;Lee, J.K.;Ryu, G.C.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.23 no.4
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    • pp.289-292
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    • 2003
  • A series of three separate experiments was contucted to investigate the effect of working time quality and animal palatability of barley whole crop silage by trench and round bale in paddy field of Central and Northern region from 1999 to 2001. Dry matter yield of trench and round bale silage was 12,562 and 12,555 MT per ha, respectively. Quality and animal palatability of silage by trench was slightly higher than those by round bale. Work time of trench silage and bale silage per ha were 4.9 and 5.7 time. Silage making areas by trench and round bale were 4 and 3ha per day, respectively, The results demonstrated that silage making by round bale was good for production cost over 7 working days.

The study on the selection of performance test conditions for indoor and outdoor experiments of snowfall in winter (겨울철 강설 실내외 실험을 위한 성능 시험 조건 선정에 관한 연구)

  • Kim, Byeongtaek;In, Sora;Kim, Sangjo
    • Journal of Korea Water Resources Association
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    • v.55 no.12
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    • pp.1149-1154
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    • 2022
  • The purpose of this research is to select representative observation stations for winter observation equipment performance tests and to present indoor and outdoor conditions for performance tests by considering snowfall, snowfall days, latitude, and altitude distribution for observation stations operated by the Korea Meteorological Administration. Using the snowfall data observed during the winter for 30 years (1981-2010), ten representative observation stations are selected to consider the classification of snowfall days by class, latitude, and altitude distribution of observation stations. As a result of analysis, the suitable point for outdoor experiments was selected as Daegwallyeong, the average number of snowfall days and snowfall days of 5cm or more were 57.5 and 13.2 days, respectively. The indoor experimental conditions are considered to be suitable under temperatures of -15 to 5℃ and humidity of 50% or higher. Results of this research can be used as basic information for conditions and test beds for performance tests of equipment that can respond to heavy snow disasters in winter.

Influence of Density and Feeding Frequency on Early Life History and Cannibalism of River Puffer, Takifugu obscurus (황복, Takifugu obscurus의 초기 생활사와 공식 행위에 있어 밀도와 먹이 공급 횟수의 영향)

  • Kang, Duk-Young;Kim, Hyo-Chan;Kang, Hee-Woong
    • Development and Reproduction
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    • v.15 no.2
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    • pp.77-85
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    • 2011
  • To investigate the influence of density and feeding frequency (food amount) on growth, cannibal dynamics and survival of puffer Takifugu obscurus (TL $25.0{\pm}0.5$ mm, BW $0.53{\pm}0.03$ g) during early life history, we conducted one experiment composed with 6 density groups set up as 1.43 inds./${\ell}$, 2.14 inds./${\ell}$, 2.86 inds./${\ell}$, 3.57 inds./${\ell}$, 4.29 inds./${\ell}$ and 7.14 inds./${\ell}$. The experiment was triplicately performed in 1 ton FRP tank for 30 days. Daily food intake (DFI), feed efficiency (FE), growth, cannibal frequency, and survival rates were examined. Although not find any significant relation of density to DFI and FE, we found that growth decreased significantly with the increasing of density under 3.57 inds./${\ell}$, but significantly increased with the increasing of density over 4.29 inds./${\ell}$. Cannibal frequency and daily mortality rate was significantly increased with increasing density and decreasing feeding frequency, inducing the most poor survival rate in the highest density group and low feeding frequency. Therefore, we concluded that the density and the feeding frequencies affect sibling cannibal dynamics and survival of puffer stock.

Development of Two-Dimensional Near-field Integrated Performance Assessment Model for Near-surface LILW Disposal (중·저준위 방사성폐기물 천층처분시설 근계영역의 2차원 통합성능평가 모델 개발)

  • Bang, Je Heon;Park, Joo-Wan;Jung, Kang Il
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.12 no.4
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    • pp.315-334
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    • 2014
  • Wolsong Low- and Intermediate-level radioactive waste (LILW) disposal center has two different types of disposal facilities and interacts with the neighboring Wolsong nuclear power plant. These situations impose a high level of complexity which requires in-depth understanding of phenomena in the safety assessment of the disposal facility. In this context, multidimensional radionuclide transport model and hydraulic performance assessment model should be developed to identify more realistic performance of the complex system and reduce unnecessary conservatism in the conventional performance assessment models developed for the $1^{st}$ stage underground disposal. In addition, the advanced performance assessment model is required to calculate many cases to treat uncertainties or study parameter importance. To fulfill the requirements, this study introduces the development of two-dimensional integrated near-field performance assessment model combining near-field hydraulic performance assessment model and radionuclide transport model for the $2^{nd}$ stage near-surface disposal. The hydraulic and radionuclide transport behaviors were evaluated by PORFLOW and GoldSim. GoldSim radionuclide transport model was verified through benchmark calculations with PORFLOW radionuclide transport model. GoldSim model was shown to be computationally efficient and provided the better understanding of the radionuclide transport behavior than conventional model.

Stability Analysis of Multiple Thermal Energy Storage Caverns Using a Coupled Thermal-Mechanical Model (열-역학적 연계해석 모델을 이용한 다중 열저장공동 안정성 분석)

  • Kim, Hyunwoo;Park, Dohyun;Park, Eui-Seob;Sunwoo, Choon
    • Tunnel and Underground Space
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    • v.24 no.4
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    • pp.297-307
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    • 2014
  • Cavern Thermal Energy Storage system stores thermal energy in caverns to recover industrial waste heat or avoid the sporadic characteristics of renewable-energy resources, and its advantages include high injection-and-extraction powers and the flexibility in selecting a storage medium. In the present study, the structural stability of rock mass pillar between these silo-type storage caverns was assessed using a coupled thermal-mechanical model in $FLAC^{3D}$. The results of numerical simulations showed that thermal stresses due to long-term storage depended on pillar width and had significant effect on the pillar stability. A sensitivity analysis of main factors indicated that the influence on the pillar stability increased in the order cavern depth < pillar width < in situ condition. It was suggested that two identical caverns should be separated by at least one diameter of the cavern and small-diameter shaft neighboring the cavern should be separated by more than half of the cavern diameter. Meanwhile, when the line of centers of two caverns was parallel to the direction of maximum horizontal principal stress, the shielding effect of the caverns could minimize an adverse effect caused by a large horizontal stress.