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DETECTION SYSTEM OF STREPTOCOCCUS MUTANS IN SALIVA USING MONOCLONAL ANTIBODY (Monoclonal Antibody를 이용한 Streptococcus mutans 검출 방법의 임상적 적용에 관한 연구)

  • Hong, Hi-Jung;Kim, Jong-Soo;Kim, Yong-Kee
    • Journal of the korean academy of Pediatric Dentistry
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    • v.36 no.4
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    • pp.522-530
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    • 2009
  • The purpose of this study was to evaluate the clinical effectiveness of new streptococcus detection system which used monoclonal antibody against Streptococcus mutans. 92 children aged between 2 and 8 were involved in this experiment and their saliva samples were collected for testing. Streptococcus mutans were measured by both monoclonal antibody-based detecting system (Saliva-$check^{TM}$ Mutans) and dip slide detecting system($Dentocult^{TM}$-SM). The results showed that Saliva-$check^{TM}$ Mutans levels had a significant correlation with dfs rate of subjects and the two test kits, Saliva-$check^{TM}$ Mutans and $Dentocult^{TM}$-SM were shown to have a good correlation although they were based on different mechanism.

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한국원자력연구소 방사선방어기술 개발 및 연구 현황

  • Ha, Jeong-U
    • Journal of Radiation Protection and Research
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    • v.15 no.1
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    • pp.9-13
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    • 1990
  • 1959년 한국원자력연구소가 창립됨과 동시에 &Health Physics&, 즉 보건물리라고 하는 명칭과 조직이 탄생되어, 방사선안전관리의 실무와 보건물리의 연구가 시작되었다. 최초 10년간은 선진제국의 보건물리분야의 연구와 기술을 추적하여 우리나라의 방사선안전관리 기술의 기초를 다지는 시기로서 개인방사선모니터링기술, 환경방사선(능) 모니터링기술 및 방사선방어용계측기기의 교정기술 개발에 중점을 두고 연구개발이 추진되었으며, TRIGA Mark-II 연구용원자로의 가동에 따라 원자로 생체차폐체의 건전성 검증에 관한 유익한 방사선량 측정자료도 얻게 되었다. 즉 이 기간은 방사선안전관리의 체제정비 및 기초기술 확립에 노력한 기간이었다. 1970년대는 원자력 연구개발에 대한 기본방향과 정책의 변경등으로 보건물리 연구조직은 방사선안전관리, 환경연구 그리고 방사화학분야로 분산되었으며, 그로인하여 연구개발활동은 거의 정체되어 겨우 방사선안전관리 실무만이 그 명맥을 유지하였다. 그 결과 우리나라 방사선안전관리 및 그와 관련된 연구개발의 기반이 흔들리게 되었으나, 그러한 환경하에서도 방사선량측정평가기술, 방사선차폐설계기술 및 원자로사고시 피폭선량평가기술의 선진화에 필요한 지식을 얻었으며, 방사선 안전관리에 유익한 실무경험도 축적하게 되었다. 1980년대는 통합된 원자력 연구개발체제의 구축으로 방사선작업종사자 및 일반공중의 피폭저감화 기술개발에 필요한 각종 최신기술을 도입하였고, 관리업무에 있어서도 측정의 정확도와 신뢰성향상 및 새로운 관리기술의 개발에 많은 노력을 한 결과, 유익한성과를 얻게된 기간이다. 특히, 이 기간은 방사선안전관리기술의 선진화를 위한 지식이 축적되어 90년대의 방사선안전관리기술자립화를 위한 전환기로서, 이와같이 축적된 기술은 원자력의 평화적 이용에 크게 기여할 것으로 기대된다.서 dithiothreitol를 투여한 군에서는 우라늄단독투여군에 비해 cretinine의 배설이 상당히 증가하였다(P<0.05). 6. 우라늄오염에 의한 신장의 소견에 있어 우라늄단독투여군은 근위곡세뇨관상피의 공포화 및 종창, microvilli와 brush border의 손실, 세뇨관 상피의 괴사가 관찰되었으며, 간장의 충혈, 중심성 괴사 및 모세관 확장증도 관찰되었다. 그리고 sodium bicarbonate와 생리적 식염수를 병행투여한 군과 우라늄을 투여하고 30분이 지나서 dithiothreitol를 투여한 군에서는 우라늄 단독투여군에 비해 높은 방호효과가 관찰되었으나 다른 실험군에서는 큰 효과가 없는 것으로 나타났다. 결론적으로 우라늄의 체내오염시에는 sodium bicarbonate와 생리적 식염수를 가능한 빨리 병행투여하거나 dithiothreitol을 체내오염후 30분이 지나서 투여하는 방법이 우라늄오염에 대한 제염에 매우 유효할 것으로 생각되며, 특히 우라늄에 의한 인체장해를 유의하게 경감시켜줄 것으로 사료되었다.내의 어떤 부위와도 관계가 되는 것으로 간주되는데 이것이 $(^3H)$ QNB가 $(^3H)$ NMS보다 높은 최대 결합능력 $(B_{max})$을 나타낼 이유이다. (b) 두 종류의 다른 제제에서 우리는 같은 양상의 결과를 관찰하었기에 결점이 많은 homogenates 제제보다는 intact cell aggregates 제제를 수용체 연구에 대한 새로운 실험모형(experiment model)으로 사용할 수 있는 가능성을 제시하고자 한다.$가 38.8%로 가장 많고, 그 다음이 ${\ulcorner}$l9세(歲)이후${\lrcorner}$가 25.2%로서 전체

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Secondary School Science Teachers' Actual and Preferred Types of Assessment (중등 과학교사의 과학 평가 실태와 지향)

  • Noh, Taehee;Lee, Jaewon;Kang, Sukjin;Kang, Hunsik
    • Journal of The Korean Association For Science Education
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    • v.35 no.4
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    • pp.725-733
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    • 2015
  • In this study, we investigated secondary school science teachers' actual and preferred types of assessment with focus on the purpose and the method of assessment. Participants were 92 secondary school science teachers. We developed a questionnaire asking science teachers about the types of assessment they have actually used and the preferred types of assessment for hypothetical situations that have been generally reported as the prototypical examples of constructivist assessment. The characteristics of the science teachers such as teaching career, experience on in-service training about assessment, and perspective toward constructivist assessment were also examined. The analysis of the actually implemented assessments in their responses revealed that most science teachers tended to aim at traditional purposes such as summative assessment, and that multiple-choice was the most prevailing assessment method followed by experiment, report, and essay. For hypothetical assessment situations, science teachers exhibited their preferences for various types of constructivist assessment methods, whereas their purposes of the assessment still remained to be traditional. The science teachers who have had a relatively constructivist perspective toward assessment showed a statistically significant preference for using formative assessment than their counterparts in the hypothetical assessment situations.

A Case Study on the Inquiry Guidance Experiences of Pre-Service Science Teachers : Resolving the Dilemmas between Cognition and Practice of Inquiry (예비 과학교사의 탐구지도 경험에 관한 사례연구 : 탐구의 인식과 실천 사이의 딜레마 해소를 중심으로)

  • Cho, Sungmin;Baek, Jongho
    • Journal of The Korean Association For Science Education
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    • v.35 no.4
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    • pp.573-584
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    • 2015
  • Inquiry has been consistently emphasized in science education as a crucial element for learning. Although many researchers came to agree on the importance of scientific inquiry, authentic inquiry activities are hard to be actualized in an educational context. Therefore it is required to critically examine what teachers have difficulty in teaching inquiry. In this article, we looked into inquiry-based science activities in a small group setting where pre-service science teachers faced dilemmas between cognition and practice of inquiry. A case study was conducted on eight undergraduate students who are majoring in science education. The participants attended a weekly science program for middle school students in low SES as teaching assistants and mentors, and took full care of his/her mentees during open-inquiry activities. The results were drawn by analyzing participants' personal and group interviews, participant observations, self-reports, and others. The pre-service teachers viewed the knowledge and procedure of science as an essential factor in inquiry activities along with student's spontaneous attitude. However, in the process of performing inquiry, they faced several dilemmas between ideal cognition and real activities. The aspects of dilemmas could be summarized in three pairs of opposing concepts: 'diverging inquiry or converging science', 'interest-centered inquiry or learning-centered inquiry', and 'student as the subject or student with the insufficient expertise.' We discussed ways of resolving dilemmas and alternative perspectives on scientific inquiry.

A Case Study on the Changes of Beginning Science-Gifted Education Teachers' Teaching Professionalism through Coteaching (코티칭을 통한 초임 과학영재교육 담당교사의 수업 전문성 변화에 관한 사례연구)

  • Noh, Tae-Hee;Yang, Chan-Ho;Kim, Young-Hoon;Kang, Hun-Sik
    • Journal of The Korean Association For Science Education
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    • v.32 no.4
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    • pp.655-670
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    • 2012
  • As a case study on the changes of beginning science-gifted education teachers' teaching professionalism through coteaching, this study deeply investigated the change processes in the aspects of pedagogical content knowledge. We selected two beginning teachers whose teaching careers in secondary science-gifted education were less than five years. The teachers planned, performed, and reflected together their science instructions for secondary science-gifted students during nine class hours over three times. We observed coteaching of science instructions of the teachers, and analyzed the taped videos, the materials, the transcripts for discussions between them and in-depth interviews with them, their reflective journals, and researcher's field notes by using the constant comparative method. This study revealed that the coteaching positively changed the two teachers' practical knowledge about the curriculum for science-gifted education, the instructional strategies for science-gifted education, the assessment in science-gifted education, the science-gifted students, and the science contents although there were some limitations. The results suggest that the coteaching will be useful in improving beginning teachers' teaching professionalism, and provide practical implications in finding the ways to use it effectively in science-gifted education.

Theoretical Considerations on Analytical Framework Design for the Interactions between Participants in Group Argumentation on Socio-Scientific Issues (사회 속 과학 쟁점에 대한 소집단 논변 상호작용 분석을 위한 방법론 고찰)

  • Park, Jee-Young;Kim, Heui-Baik
    • Journal of The Korean Association For Science Education
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    • v.32 no.4
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    • pp.604-624
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    • 2012
  • This study aims to design a framework for analyzing group argumentation in terms of participants' interaction. Regarding the current group argumentation setting as argumentation on socio-scientific issues within participants who have had limited experience on group argumentation, the analytical framework was designed to explain (1) what was each participant's role on group argumentation, (2) how these roles were changed within each time of argumentation, and (3) how the patterns of interaction were changed through seven times of a series of argumentation on socio-scientific issues. Based on the literature review on analytical framework of argumentation in science education including the works on the structure of argumentation, the discourse formation through interaction, and the linguistic approach on participants' interaction, the current research framework was built. Showing the results of applying the designed framework on group argumentation as an example, strength of using the current designed framework was discussed.

A Study on Learning Motivation and Self-regulated Learning of Students in Hotel and Food Service Related Departments - Focused on College Students in the Daegu.Gyeongbuk Areas - (호텔.외식조리 관련학과 학생들의 학습동기 및 자기조절학습능력에 관한 연구 - 대구.경북 지역 전문대 학생을 중심으로 -)

  • Kim, Gi-Jin;Kim, Hyang-Hee;Chung, Eio-Sook
    • Culinary science and hospitality research
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    • v.16 no.3
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    • pp.130-146
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    • 2010
  • This research examines difference in learning motivation and self-regulated learning according to the general characteristics of the students in hotel and food service related departments at vocational colleges, and subsequently identifies correlation between the two attributes. The research conducted a survey for 300 students in hotel and food service related departments at three vocational colleges in Daegu region, and 267 copies were used for the final analysis. In terms of learning motivation, students in the age between 20 and 24 indicated 'employment after graduation' as the strongest motivation while relatively older students indicated 'joy of learning' as their motivation. It turned out that students who showed strong motivation in terms of 'employment after graduation' and 'fun of college life' acquired more professional certificates. Next, regarding self-regulated learning, female students showed higher ability than male students. Students in higher grade, with older age, and with field practice experience showed more strength in self-regulated learning. Students with higher levels of a cognitive strategy, meta cognition and achievement value acquired more professional certificates. Learning motivation and self-regulated learning showed positive correlation with an exception of 'amotivation' among learning motivations. 'Amotivation' demonstrated negative correlation with all the factors of self-regulated learning ability.

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Effects of the External Variables of the RFID System for Eco-friendly Agricultural Products on Perceived Value and Behavioral Intention : Applying an Expanded TAM (친환경농산물 RFID 시스템의 외부변수들이 지각된 가치 및 행동의도에 미치는 영향 : 확장된 TAM 모델을 적용하여)

  • Choi, Won-Sik;Lee, Soo-Bum
    • Culinary science and hospitality research
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    • v.19 no.2
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    • pp.149-166
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    • 2013
  • The purpose of this study is to investigate what influence the external variables of the RFID system for eco-friendly agricultural products such as reliability, safety, effectiveness and innovation have on ease and usefulness, perceived value and behavioral intention. An empirical analysis were conducted to the general consumers over the age of 20 years who live in Seoul and Gyeonggi areas having experience of buying eco-friendly agricultural products in department stores, supermarkets and eco-friendly agricultural product specialty stores from November 10 to November 23, 2012, A total of 350 copies of questionnaire were distributed for this research and, excluding partial ones that were too concentrated on one side or found missing values, a total of 305 copies(87.1%) were used as the final statistical analysis data. The result shows that such external variables of the RFID system for eco-friendly agricultural products as liability, safety, effectiveness and innovation are useful enough as a theoretical basis for later study on RFID systems for eco-friendly agricultural products. Also, it reveals that, since all the process from production to sale of agricultural products can be seen, the products are provided safely for consumers, are objectively and rapidly investigated when problems occur, induce a positive attitude with their historical information, and are supplied through systematic management such as consumers' rights to know and choose and recall of unfit products.

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A Study on the Reasonable Application Method of Steel Fiber Reinforced Shotcrete in NATM Tunnel (NATM 터널에서 합리적인 강섬유보강 숏크리트 적용방안에 관한 연구)

  • Seok, Chongken;Ahn, Taebong
    • Journal of the Korean GEO-environmental Society
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    • v.15 no.9
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    • pp.19-28
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    • 2014
  • Recently, the proportion of long tunnel has increased for efficient use of land due to limited land area, driving convenience and high speed. RMR and Q-System of empirical methods has been mainly used for tunnel support design in domestic. Although shotcrete is the key to NATM tunnel, the related studies are insufficient. So, steel fiber reinforced shotcrete is applied to II~V grade rocks on domestic and foreign applications. And same amount of shotcrete is equally applied to tunnel roof and wall regardless of the applied rock load. Shotcrete is applied excessively rather than the original proposed value of RMR and Q-System. Thus, this study is to reevaluate the application part of plain shotcrete and steel fiber reinforced shotcrete of tunnel in Daebo granite, and to propose the reasonable application method of steel fiber reinforced shotcrete. Field test and numerical back analysis using measurements were performed to verify stability. According to results, if RMR values are the upper class in the III grade, it can be designed in accordance with upper grade. In addition, if rock condition is good as a mountain tunnel in Daebo granite, it can be applied for plain shotcrete to III grade rocks because there is also no stability problems. And although steel fiber reinforced shotcrete is applied only crown of the tunnel in IV grade rocks, it is possible to secure stability for falling rock by key-block.

Structural and Functional Changes of Hippocampus in Long Life Experienced Taxi Driver (오랜 운전경험을 가진 택시운전기사들의 해마의 구조와 기능적 변화에 대한 MRI연구)

  • You, Myung-Won;Lee, Dong-Kyun;Lee, Jong-Min;Kim, Sun-Mi;Ryu, Chang-Woo;Kim, Eui-Jong;Jahng, Geon-Ho
    • Investigative Magnetic Resonance Imaging
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    • v.16 no.2
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    • pp.124-135
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    • 2012
  • Purpose : The objective of this study was to investigate the differences of hippocampal volume and shape as well as the functional change between long life experienced taxi drivers and controls of Korean population. Materials and Methods: Three-dimensional T1-weighted images and blood oxygen level dependent functional MRI(fMRI) were obtained from 8 subjects, consisting of 4 experienced (20-30 years) taxi drivers and 4 age-matched controls. The hippocampal volume and shape were analyzed with three-dimensional T1-weighted images. In addition, neuronal activities of brain were analyzed using a blood oxygen level dependent fMRI between the two groups. Results: The hippocampal volume showed no statistically significant difference between the two groups (p > 0.05). The left hippocampi of the taxi drivers were slightly elongated with larger head and tail portions than those of the controls (p < 0.05, uncorrected). For the functional MRI, fusiform gyrus was specifically activated in taxi drivers, compared with the control group. Conclusion: The structural and functional changes of taxi driver's hippocampus indicate the functional differentiation as a result of occupational dependence on spatial navigation. In other words, the continuous usage of spatial navigation performance may diminish degeneration of hippocampus and the related brain regions.