• Title/Summary/Keyword: 비최소위상

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Effect of Antibiotic Combination Therapy on Metallo-${\beta}$-Lactamase Producing Imipenem Resistant Pseudomonas aeruginosa (Metallo-${\beta}$-lactamase를 생성하여 Imipenem에 내성인 Pseudomonas aeruginosa에 대한 항균제 병합요법의 효과)

  • Hong, Seung-Bok;Kim, Hong Chul;Lee, Jang-Won;Son, Seung-Yeol
    • Korean Journal of Microbiology
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    • v.44 no.4
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    • pp.339-345
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    • 2008
  • This study was to detect MBL (metallo-${\beta}$-lactamase) among glucose non-fermenting Gram-negative bacilli isolated from clinical specimen and to search antimicrobial combination therapy against MBL producing Pseudomonas aeruginosa. Among fifty one isolates of Gram-negative bacilli with reduced imipenem susceptibility ($MIC{\ge}8{\mu}g/ml$), nine isolates have shown positive results in MBL detection test. They were seven Achromobacter xylosoxidans subsp. xylosoxidans and two P. aeruginosa. The results from EDTA-DDST coin-cided with those of PCR and nucleotide sequence analysis which showed the presence of $bla_{VIM-2}$. The combination of aztreonam (AZT) and piperacillin-tazobactarn (TZP) or AZT and amikacin (AN) screened by one disk synergy test showed no synergistic effect. Triple antibiotic combination therapy with AZT, TZP and AN, however, was shown to be effective and the most synergistic after 8 hrs of exposure. This result strongly suggest that the triple combination therapy of AZT, TZP, and AN could be useful for the treatment of infection caused by MBL producing Gram-negative bacilli.

Effects of oxygen partial pressure on the properties of indium tin oxide film on PET substrates by RF magnetron sputtering (RF 마그네트론 스퍼터링법에 의해 PET 기판 위에 증착된 ITO 박막의 특성에 대한 산소 분압의 영향)

  • Kim, Seon Tae;Kim, Tae Gyu;Cho, Hyun;Kim, Jin Kon
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.24 no.6
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    • pp.252-255
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    • 2014
  • Indium tin oxide (ITO) films with various oxygen partial pressure from 0 to $6{\times}10^{-5}$ Pa were prepared onto polyethylene terephthalate (PET) using RF magnetron sputtering at room temperature. The structural, electrical and optical properties of the grown ITO films were investigated as a function of the oxygen partial pressure. The amorphous nature of the ITO films was dominant at the partial pressure below $1{\times}10^{-5}$ Pa and the degree of crystallinity increased as the oxygen concentration increased further. This structural change comes with the increased carrier concentration and reduction of the electrical resistivity down to $9.8{\times}10^{-4}{\Omega}{\cdot}cm$. The average transmittance (at 400~800 nm) of the ITO deposited on the PET substrates increased as the oxygen partial pressure increased and transmittance above 80 % was achieved with the partial pressure of $4{\times}10^{-5}$ Pa. The results show that the choice of optimal oxygen partial pressure can present improved film crystallinity, the increased carrier concentration, and the enhancement in the electrical conductivity.

Plowing Performance in the Paddy Field Spread with Rice Straw in Spring (논의 볏짚 시용(施用)이 춘계리경작업(春季犁耕作業) 성능(性能)에 미치는 영향(影響))

  • Park, Woo Pung;Kim, Soung Rai
    • Journal of Biosystems Engineering
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    • v.8 no.1
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    • pp.9-16
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    • 1983
  • This study was conducted to find out the effects of such parameters as specific draft resistance, slip rate, and fuel consumption rate on plowing performance in paddy fields spread with chopped rice straw. The plowing operation by an 8 P.S. power tiller was carried out in 6 different fields having the soil moisture content of 27~36 percent in dry basis in clay loam soil texture, and applying chopped rice straw of 10, 20, 30 and 60cm in length in the spring of 1982. The effects of soil hardness and moisture content on the plowing performance were also investigated. The results of the study are summarized as follows; 1. The minimum draft during the plowing operation was 110kg in the 30cm rice straw plot having the soil moisture content of 32 percent in dry basis. 2. The multiple regression equation of the specific draft(D) as a function of soil moisture content(M) and cutting length of rice straw(L) was obtained as follows. $D=14.1978-0.8565M+0.0661LxM-2.9685L+0.0133M^2+1.093L^2$ 3. In the 30cm rice straw plot with the soil moisture content of 32 percent in dry basis, the minimum specific draft resistance and the rate of slip were 0.35kg per $cm^2$ and 16 percent respectively. The specific draft resistance varied sensitively in accordance with the soil moisture content, and the slip rate of power tiller was dependent upon the cutting length of rice straw rather than the soil moisture content. 4. The highest plowing performance was 5.3 ares per hour at the soil moisture content of 35 percent and soil hardness of 10kg per $cm^2$. The relationship between the plowing performance and the soil moisture content was obtained by a quadratic equation. 5. The minimum fuel consumption rate in the plowing operation was recorded 6.5 liters per 10 ares in 30cm chopped rice straw plot with the soil moisture content of 32 percent in dry basis.

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Classification of the Core Climatic Region Established by the Entropy of Climate Elements - Focused on the Middle Part Region - (기후요소의 엔트로피에 의한 핵심 기후지역의 구분 - 중부지방을 중심으로 -)

  • Park, Hyun-Wook;Chung, Sung-Suk;Park, Keon-Yeong
    • Journal of the Korean earth science society
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    • v.27 no.2
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    • pp.159-176
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    • 2006
  • Geographic factors and mathmatical location of the Korean Peninsula have great influences on the variation patterns and appearances over a period of ten days of summer precipitation. In order to clarify the influence of several climate factors on precise climate classification in the middle part region of the Korea, weather entropy and the information ratio were calculated on the basis of information theory and of the data of 25 site observations. The data used for this study are the daily precipitation phenomenon over a period of ten days of summer during the recent thirteen years (1991-2003) at the 25 stations in the middle part region of the Korea. It is divided into four classes of no rain, $0.1{\sim}10.0mm/day,\;10.1{\sim}30.0mm/day$, 30.1mm over/day. Their temporal and spatial change were also analyzed. The results are as follows: the maximum and minimum value of calculated weather entropy are 1.870 bits at Chuncheon in the latter ten days of July and 0.960 bits at Ganghwa during mid September, respectively. And weather entropy in each observation sites tends to be larger in the beginning of August and smaller towards the end of September. The largest and smallest values of weather representative ness based on information ratio were observed at Chungju in the beginning of June and at Deagwallyeong towards the end of July. However, the largest values of weather representativeness came out during the middle or later part of September when 15 sites were adopted as the center of weather forecasting. The representative core region of weather forecasting and climate classification in the middle part region of the Korea are inside of the triangle region of the Buyeo, Incheon, and Gangneung.

Influence of Detailed Structure and Curvature of Woven Fabric on the Luminescence Effect of Wearable Optical Fiber Fabric (직물의 세부 구조 및 굴곡이 웨어러블 광섬유의 발광 효과에 미치는 영향)

  • Yang, Jin-Hee;Cho, Hyun-Seung;Kwak, Hwy-Kuen;Oh, Yun-Jung;Lee, Joo-Hyeon
    • Science of Emotion and Sensibility
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    • v.21 no.4
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    • pp.55-62
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    • 2018
  • The two main requirements of wearable optical fiber fabrics are that they must presuppose a high degree of flexibility and they must maintain the luminance effect in both flat and bent conformations. Therefore, woven optical fiber fabrics that satisfy the above conditions were developed by both weaving and by using computer embroidery. First, we measured the brightness of the wearable optical fiber fabric in the flat state at a total of 10 measurement points at intervals of 1 cm. Second, the wearable optical fiber fabric was placed horizontally on the forearm, where three-dimensional bending occurs, and the luminance values were recorded at the same 10 measurement points. For the woven fabric in the flat state, the maximum, minimum, average, and standard deviation luminance values were $5.23cd/m^2$, $2.74cd/m^2$, $3.56cd/m^2$, and $1.11cd/m^2$, respectively. The corresponding luminance values from the bent forearm were $7.92cd/m^2$ (maximum), $2.37cd/m^2$ (minimum), $4.42cd/m^2$ (average), and $2.16cd/m^2$ (standard deviation). In the case of the computer-embroidered fabric, the maximum, minimum, average, and standard deviation luminance values in the flat state were $7.56cd/m^2$, $3.84cd/m^2$, $5.13cd/m^2$, and $1.04cd/m^2$, respectively, and in the bent forearm state were $9.6cd/m^2$, $3.63cd/m^2$, $6.13cd/m^2$, and $2.26cd/m^2$, respectively. Therefore, the computer-embroidered fabric exhibited a higher luminous effect than the woven fabric because the detailed structure reduced light-loss due to the backside fabric. In both types of wearable optical fiber fabric the luminance at the forearm was 124% and 119%, respectively, and the light emitting effect of the optical fiber fabric was maintained even when bent by the human body. This is consistent with the principle of Huygens, which defines the wave theory of light, and also the Huygens-Fresnel-Kirchhoff principle, which states that the intensity of light increases according to the magnitude of the angle of propagation of the light wavefront (${\theta}$).

Methods of Incorporating Design for Production Considerations into Concept Design Investigations (개념설계 단계에서 총 건조비를 최소로 하는 생산지향적 설계 적용 방법)

  • H.S.,Bong
    • Bulletin of the Society of Naval Architects of Korea
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    • v.27 no.3
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    • pp.131-136
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    • 1990
  • 여러해 전부터 선박의 생산실적이나 생산성 관련 자료를 기록하고 보완하는 작업을 꾸준히 개선토록 노력해온 결과중 중요한 것 하나는, 선박의 여러 가지 설계 검토과정에서 충분히 활용할 수 있는 함축성 있고 믿을만한 형태의 생산정보를 제공해줄 수 있게 되었다는 것이라고 말 할 수 있겠다. 이러한 자료들은 생산계획상 각 단계(stage)에서의 작업량, 예상재료비와 인건비의 산출등이 포함될 수 있으며, 선박이나 해상구조물의 전반적인 설계방법론(design methodology)을 개선코자 한다면 ''생산지향적 설계(Design for Production)''의 근간이 되는 선박건조전략(build strategy), 구매정책(purchasing policy)과 생산기술(production technology)에 대한 폭넓은 지식이 한데 어우러져야 한다. 최근에는 CIMS의 일부분에서 보는 바와 같은 경영관리, 설계 및 생산지원 시스템의 도입으로 이와 같은 설계 프로세스의 추진을 가능케하고 있다. 이와 병행하여 설계를 지원하기 위한 전산기술, 특히 대화형 화상처리기술(interactive graphics)의 발달은 설계자가 선박의 형상이나 구조 배치를 여러 가지로 변화시켜 가면서 눈으로 즉시 확인할 수 있도록 설계자의 능력을 배가시키는데 크게 기여하고 있다. 여러 가지의 설계안(alternative design arrangement)을 신속히 만들어내고 이를 즉시 검토 평가할 수 있는 능력을 초기설계 단계에서 가질 수 있다면 이는 분명히 큰 장점일 것이며, 더구나 설계초기 단계에 생산관련인자를 설계에서 고려할 수 있다면 이는 더욱 두드러진 발전일 것이다. 생산공법과 관련생산 비용을 정확히 반영한 각 가지의 설계안을 짧은 시간내에 검토하고 생산소요 비용을 산출하여 비교함으로써, 수주계약단계에서 실제적인 생산공법과 신뢰성있는 생산실적자료를 기준으로 하여 총 건조비(total production cost)를 최소로 하는 최적의 설계를 선택할 수 있도록 해 줄 것이다. 이제 이와 같은 새로운 설계도구(design tool)를 제공해 주므로써 초기설계에 각종 생산관련 정보나 지식 및 실적자료가 반영가능토록 발전되었다. 본 논문은 영국의 뉴카슬대학교(Univ. of Newcastle upon Type)에서 위에 언급한 특징들을 반영하여 새로운 선박구조 설계 방법을 개발한 연구결과를 보여주고 있다. 본 선계연구는 5단계로 구분되는데; (1) 컴퓨터 그라픽스를 이용하고 생산정보 데이타베이스와 연결시켜 구조형상(geometry)을 정의하고 구조부재 칫수(scantling) 계산/결정 (2) 블럭 분할(block division) 및 강재 배치(panel arrangement)의 확정을 위해 생산기술 및 건조방식에 대한 정보 제공 (3) 상기 (1) 및 (2)를 활용하여 아래 각 생산 단계에서의 생산작업 분석(work content assessment) a) 생산 준비 단계(Preparation) b) 가공 조립 단계(Fabrication/Assembly) c) 탑재 단계(Erection) (4) 각각의 설계(안)에 대하여 재료비(material cost), 인건비(labour cost) 및 오버헤드 비용(overhead cost)을 산출키 위한 조선소의 생산시설 및 각종 품셈 정보 (5) 총 건조 비용(total production cost)을 산출하여 각각의 설계안을 비교 검토. 본 설계 방식을 산적화물선(Bulk Carrier) 설계에 적용하여 구조배치(structural geometry), 표준화의 정도(levels of standardisation), 구조생산공법(structural topology) 등의 변화에 따른 설계 결과의 민감도를 분석(sensitivity studies)하였다. 전산장비는 설계자의 대화형 접근을 용이하도록 하기 위해 VAX의 화상 처리장치를 이용하여 각 설계안에 대한 구조형상과 작업분석, 건조비 현황 등을 제시할 수 있도록 하였다. 결론적으로 본 연구는 설계초기 단계에서 상세한 건조비 모델(detailed production cost model)을 대화형 화상 처리방법에 접합시켜 이를 이용하여 여러가지 설계안의 도출과 비교검토를 신속히 처리할 수 있도록 함은 물론, 각종 생산 실적정보를 초기설계에 반영하는 최초의 시도라고 믿으며, 생산지향적(Design for Production) 최적설계분야의 발전에 많은 도움이 되기를 기대해 마지 않는다. 참고로 본 시스템의 설계 적용결과를 부록에 요약 소개하며, 상세한 내용은 참고문헌 [4] 또는 [7]을 참조 요망한다.

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Method for Determining Variable-Block Size of Depth Picture for Plane Coding (깊이 화면의 평면 부호화를 위한 가변 블록 크기 결정 방법)

  • Kwon, Soon-Kak;Lee, Dong-Seok
    • Journal of Korea Society of Industrial Information Systems
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    • v.22 no.3
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    • pp.39-47
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    • 2017
  • The Depth Picture can be Encoded by the Plane Coding Mode that is the Method for Coding Mode by Considering a Part of the Picture as the Plane. In this Paper, we Propose the Method of Determining the Variable-sized Block for Variable Block Coding in the Plane Coding Mode for the Depth Picture. The Depth Picture Can be Encoded in the Plane Coding Through Estimating the Plane Which is Close to Pixels in the Block Using Depth Information. The Variable-sized Block Coding in the Plane Coding can be Applied as Follows. It Calculates the Prediction Error between Predicted Depths by the Plane Estimation and the Measured Depths. If Prediction Error is Below the Threshold, the Block is Encoded by Current Size. Otherwise, it Divides the Block and Repeats Above. If the Block is Divided Below the Minimum Size, the Block is not Encoded by the Plane Coding Mode. The Result of the Simulation of the Proposed Method Shows that the Number of Encoded Block is Reduced to 19% as Compared with the Method Using the Fixed-sized Block in the Depth Picture Composed of one Plane.

최적화알고리듬을 이용한 세기변조방사선치료의 정량적인 정도관리

  • Park, Dong-Hyun;Park, Dal;Park, Sung-Yong;Kim, Tae-Hyun;Shin, Kyung-Hwan;Kim, Dae-Yong;Cho, Kwan-Ho
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2003.09a
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    • pp.35-35
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    • 2003
  • 목적 : 세기변조방사선치료의 정도관리 중 선량 분포의 비교에 관한 새로운 정량적인 방법을 제시하였다. 이 과정 중에서 선량의 기울기가 큰 영역에서의 문제점을 해결하기 위하여 최적화 알고리듬을 사용하였다. 대상 및 방법 : 필름을 통해 측정된 선량분포와 컴퓨터를 통해 구해진 선량분포를 각각 5mm 간격과 lmm 간격의 해상도로 컴퓨터를 이용해 2 차원 선량분포로 구현한다. 그 후 두 선량분포사이의 차이를 각 선량분 포의 원점을 일치시킨 후 구해낸다. 이때 일반적으로 두 선량분포 사이의 차이는 선량의 기울기가 큰 영역에서 상당히 크게 나타나게 되는데 이것은 측정 장비의 원점을 구하는 과정에서 발생되는 이차원 상의 미세한 원점의 불일치 효과로 선량의 차이가 선량의 기울기가 큰 영역에서 더욱 커지기 때문이다. 이 불일치를 보정하기 위해서, 측정된 선량분포를 계산된 선량분포 위에서 lmm 간격으로 이동시켜가면서 선량의 차이를 계산하여 이 값이 최소가 되는 위치를 확인한다. 이때의 이동치는 가속기가 갖는 허용오차 이내에 있어야 하며 이 값은 2mm로 알려져 있다. 이 과정과는 독립적으로 이온 챔버를 통해 측정된 절대선량 값을 이용하여 두 선량분포 사이를 재 규격화한 뒤 차이를 구하게 되면 우리는 5mm 간격의 2 차원 절대선량 분포 비교를 실험상의 오차들 중 가장 크게 작용하는 원점 오차로 인한 오차를 제거한 뒤 수행한 것과 같은 결과를 얻게 된다. 여기서 계산된 선량분포의 해상도는 장비의 허용오차 보다 항상 작아야 한다. 결과 : 머리와 목에 환부를 갖는 여러 환자들에 대한 선량분포 비교 결과를 통해서, 측정된 선량분포와 계산된 선량분포사이의 허용오차 범위에 대한 일시적 기준을 마련하였다. 이 기준은 물론 더 많은 환자들에 대한 선량분포 비교를 통해 개선되어질 수 있다. 결론 : 측정 장비의 원점 불일치의 보정뿐만 아니라 측정 장비의 회전에 의한 오차 보정, 필름의 광학적 밀도에 관한 보정 등 여러 가지 계통적 오차들에 대한 보정들이 선량분포 확인과정의 이해와 그 기준마련에 도움이 되겠지만 우리가 다룬 원점 불일치에 비해서 상대적으로 무시할 수 있었다. 마지막으로 선량분포 확인의 최종목표인 3 차원 선량분포 확인의 실제 적용을 위한 연구가 최적화 알고리듬을 이용하여 실험 중에 있다.

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A Study on Serials Cancellation and Alternatives to Subscription in the Electronic Age (디지털세대의 연속간행물 구독취소와 대응방안에 관한 연구)

  • 신은자
    • Journal of the Korean Society for information Management
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    • v.18 no.1
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    • pp.105-126
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    • 2001
  • Serials subscription prices continue to escalate but university library budgets of those have not grown concurrently at the same rate. In fact, library budgets of serials subscription have decreased as a percentage of total library expenditure. Also titles with little or no use should be cancelled to make room for new serials that might be needed to reflect new research interests or changes in curriculum. This study includes overview of the serials cancellation and substitute solutions for subscriptions in university library. Taking into account costs and coverages, availability of cancelled serials through interlibrary loan is high in general. There is a potential for considerable savings by providing access to low-use titles, and that is a combination of commercial document delivery and pay per view based on e-business could be a viable alternative to subscription in many cases.

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Diffusion Weighted Imaging in Musculoskeletal MRI: Analysis on Optimal Number of Excitations Providing better Differentiation of Maglignant Tumor (악성종양의 감별진단을 위한 근골격의 확산강조영상 검사 시 최적의 여기횟수)

  • Choi, Kwan-Woo
    • The Journal of the Korea Contents Association
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    • v.18 no.8
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    • pp.338-344
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    • 2018
  • The purpose of this study was to determine the optimal number of excitations(NEX) of diffusion weighted imaging(DWI) which is clinically useful in patients with musculoskeletal diseases while the scan time is relatively long. In this study, 30 patients underwent knee MRI using diffusion weighted image sequence using b values targeted on the bone and muscle. The NEX were varied from 1 to 5 and the ADC values were measured and analyzed. As a result of the study, 4 NEX and 2 NEX showed an statistically identical effect with the existing NEX on the bone and muscle diffusion weighted images, respectively. Also, it proved that the scan time could be significantly reduced by 21.2 % and 59.6 % compared to the established NEX which meant the optimal NEX could replace the existing NEX. In conclusion, applying the optimal NEX on the musculoskeletal bone and soft tissue DWI could improve the problems caused by the long scan time.