• Title/Summary/Keyword: 비장전이

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Total Body Irradiation for Allogeneic Bone Marrow Transplantation in Chronic Myelogenous Leukemia (만성 골수성 백혈병에서 동종 골수 이식을 위한 전신방사선조사)

  • Chung Su Mi;Choi Ihl Bohng;Kang Ki Mun;Kim In Ah;Shinn Kyung Sub;Kim Choon Choo;Kim Dong Jip
    • Radiation Oncology Journal
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    • v.12 no.2
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    • pp.209-217
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    • 1994
  • Between July 1987 and December 1992, we treated 22 patients with chronic myelogenous leukemia; 14 in the chronic phase and 8 with more advanced disease. All were received with allogeneic bone marrow transplantation from HLA-identical sibling donors after a total body irradiation(TBI) cyclophosphamide conditioning regimen. Patients were non-randomly assigned to either 1200 cGy/6fractions/3days (6 patients) or 1320 cGy/8 fractions/4days (16 patients) by dose of TBI. Of the 22 patients, 8 were prepared with cyclophosphamide alone, 14 were conditioned with additional adriamycin or daunorubicin. To prevent graft versus host disease, cyclosporine was given either alone or in conjunction with methotrexate. The actuarial survival and leukemic-free survival at four years were $58.5\%$ and $41.2\%$, respectively, and the relapse rate was $36\%$ among 22 patients. There was a statistically significant difference in survival between the patients in chronic phase and more advanced phase ($76\%\;vs\;33\%$, p=0.05). The relapse rate of patients receiving splenectomy was higher than that of patients receiving splenic irradiation ($50\%\;vs\;0\%$, p=0.04). We conclude that the probability of cure is highest if transplantation is performed while the patients remains in the chronic phase.

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Analysis of Prescriptions from Taepyeonghyeminhwajegukbang, Somunsunmyungronbang and Nansilbijang (『태평혜민화제국방(太平惠民和劑局方)』과 『소문선명론방(素問宣明論方)』과 『난실비장(蘭室秘藏)』의 방제구성 비교)

  • Wu, Yueh-Hwan;Kim, Ki-Wook;Lee, Byung-Wook;Kim, Eun-Ha
    • Journal of Korean Medical classics
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    • v.27 no.4
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    • pp.121-131
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    • 2014
  • Objectives : The objectives of this study is to compare the differences in medical herbs combination of Taepyeonghyeminhwajegukbang, Somunsunmyungronbang and Nansilbijang. Methods : This study was proceeded by using Access 2007 and SQL Server and prescriptions of which herbal configuration could be indicated by weight unit were analysed from 765 prescriptions of Taepyeonghyeminhwajegukbang, 350 prescriptions of Somunsunmyungronbang and 277 prescriptions of Nansilbijang. Results : If more than 80% similarity, it is considered similar prescription. Only 6 Prescriptions of Nansilbijang similar to Prescriptions of Taepyeonghyeminhwajegukbang. And 20 Prescriptions of Somunsunmyungronbang similar to Prescriptions of Taepyeonghyeminhwajegukbang. Conclusions : Configuration patterns of Somunsunmyungronbang and Nansilbijang are different from Taepyeonghyeminhwajegukbang. So We can prove that theory of Somunsunmyungronbang and Nansilbijang are different from Taepyeonghyeminhwajegukbang.

A Case of Idiopathic Thrombocytopenic Purpura in Pregnancy (임신과 동반된 특발성 혈소판 감소성 자반증 1례)

  • Kim, Mi-Sook;HwangBo, Ho-Joon;Lee, Young-Gi;Park, Yoon-Kee;Lee, Sung-Ho
    • Journal of Yeungnam Medical Science
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    • v.10 no.2
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    • pp.512-517
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    • 1993
  • Idiopathic thrombocytopenic purpura is an uncommon illness but most common form of thrombocytopenia in pregnancy. Corticosteroids, splenectomy, immunosuppressive drugs, and immunoglobulin therapy have been recommended for management. The optimal method of delivery is controversial. We have experienced a case of idiopathic thrombocytopenic purpura diagnosed previously and managed with corticosteroid and vincristine, which was followed by pregnancy, vaginal delivery and postpartum splenectomy.

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Immunomodulatory Effects of Dietary Safflower Leaf in Chickens

  • Lee, Sung-Hyen;Lillehoj, Hyun S.;Cho, Soo-Muk;Park, Dong-Woon;Hong, Yeong-Ho;Chun, Hye-Kyung;Lillehoj, Erik P.
    • The Korean Journal of Community Living Science
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    • v.18 no.4
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    • pp.715-724
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    • 2007
  • 홍화 (Carthamus tinctorius)는 오래 전부터 각종 감염성 질환이나 암을 치료하는데 효과가 있는 것으로 알려져 왔다. 최근 각종 천연산물에 사람과 동물의 건강을 증진시키는 효과가 있는 것이 밝혀지면서, 홍화의 면역조절 효과에 대한 관심이 높아지고 있으나 이에 대한 과학적 자료가 부족한 실정이다. 따라서, 본 연구는 홍화의 면역 조절 활성을 확인하기 위해 수행되었으며, 면역능 실험을 위해 주로 이용되는 실험용 닭(White Leghorn chickens)에게 홍화잎을 첨가한 실험식이를 3주간 급여한 후 관련 요인들을 분석하였다. 실험 결과, 홍화잎을 섭취한 실험동물에서 비장 면역세포의 증식이 많았고, $Y{\delta}$-TCR+ 세포의 비율이 높아졌으며, 십이지장에서는 IFN-Y, IL-8, IL-10, IL-15 및 NK-lysin 같은 사이토카인의 발현이 높아졌다. 따라서, 홍화잎은 식이와 함께 급여하였을 때 면역 증강 효과가 있는 것으로 밝혀졌으며, 홍화잎을 이용한 각종 제품 개발이 기대된다.

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A Study on the Function of Pi(脾) in Huangdineijing (『황제내경(黃帝內經)』에 나타난 비장(脾臟)의 기능에 대한 고찰(考察))

  • Kim, Jong-hyun;Jeong, Chang-hyun;Jang, Woo-chang;Baik, You-sang
    • Journal of Korean Medical classics
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    • v.28 no.3
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    • pp.141-158
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    • 2015
  • Objectives : This paper examines how the Pi(脾) function was understood in the time of the Huangdineijing. Methods : The contents were analyzed and categorized through examining the verses within the Huangdineijing, followed by comparison with a recent publication on the topic. Results &Conclusions : According to the Huangdineijing, there are two major functions of the Spleen. One is producing and distributing Jing Qi from food, the other is managing the Qi cycle of the body. The former function could again be sub-categorized into the part focusing on production and that focusing on distribution. In the Huangdineijing Yanjiu Dacheng(黃帝內經硏究大成, Great Findings from the Study of Hungdineijing) the contents were mostly similar, with the exception of some parts.

A Review on Spleen Possesses Nutrient, Liver Possesses Blood and Kidney Possesses Essence (비장영(脾藏營) 간장혈(肝藏血) 신장정(腎藏精)에 대(對)한 고찰(考察))

  • Song, Ji-Chung;Keum, Kyung-Soo;Eom, Dong-Myung
    • Journal of Korean Medical classics
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    • v.24 no.3
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    • pp.71-74
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    • 2011
  • Objective : Nutrient Qi, Blood Qi and Essencial Qi are the most significant qi in spleen, liver and kidney. However, the origins and functions of those qi are not quite detailed somehow. Method : I will try to find out the origins and functions of Nutrient Qi, Blood Qi and Essencial Qi through "Hwangdineijing". Result : The Nutrient Qi is the essence of spleen, Blood Qi is the essence of liver and Essencial Qi is the essence of kidney. Conclusion : The Nutrient Qi has function of nourishment in human body and digestion of water and food in spleen itself. The Blood Qi has a function to make each organ work in human body and to make free coursing in liver itself. Essential Qi has a function to store each essential qi of five viscera in human body and reproduction in kidney itself.

Design and Implementation of the On-line Aptitude Test System for People with Visual Impairment (시각 장애인용 온라인 적성검사 시스템의 설계 및 구현)

  • Ban, Chae-Hoon;Park, Hye-Jeon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.6
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    • pp.1105-1110
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    • 2009
  • Vocational rehabilitation is defined as a process which helps people with disabilities to maintain life of non-disabled people and vocational assessment is a part of it. Traditionally, vocational assessment is performed through using of assessment tools, vocational counseling and so on. It is very efficient to apply vocational assessment to people with disabilities using the internet, but we should provide them with web accessibility. In this paper, we design and implement the aptitude test system for people with visual impairment supporting web accessibility. We develop the aptitude test system using the Holland Test which is the assessment tool of career guidance and counseling. We also show that the aptitude test system for people with visual impairment supports web accessibility more than previous Holland Test which is served in the internet.

Anti-Oxidative Effect of Soyangin Hyeongbangpaedok-san Decoction in Kidney and Spleen Cells of Aged Rats (소양인(少陽人) 형방패독산(荊防敗毒散) 전탕액이 노화쥐의 신장과 비장 세포의 항산화능에 미치는 영향)

  • Min, Gyeong-Hoon;Ahn, Taek-Won
    • Journal of Sasang Constitutional Medicine
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    • v.22 no.1
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    • pp.49-58
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    • 2010
  • 1. Objectives: The purpose of this study is to find out the Anti-Oxidative effects of Soyangin Hyeongbangpaedok-san(HBP) in kidney and spleen cells of aged rats. 2. Methods: Aged rats used in this experiment were 6, 52, 68 weeks old. Each age group was divided into three groups again. One group was given no treatment, another group was dosed normal saline and the other group was dosed HBP decoction. The antioxidant effects of HBP decoction were measured by the levels of SOD, GSH, MDA and NO. 3. Results: and Conclusions: 1) The activity of SOD was significantly increased in kidney cells of 68w-HBP group. Deterioration of the activity of SOD in kidney cells was significantly suppressed according to increasing in age of the week. 2) The level of NO was significantly decreased in kidney cells of 68w-HBP group. Deterioration of The level of NO in kidney cells was significantly suppressed according to increasing in age of the week. 3) The activity of SOD was increased in spleen cells of 52w and 68w-HBP group. 4) The level of GSH was significantly increased in spleen cells of 68w-HBP group.

Clinical Application of the Spleen Daoyin Method(脾臟導引法) in the 『Donguibogam(東醫寶鑑)』 (『동의보감(東醫寶鑑)』 비장도인법(脾臟導引法)의 임상적 활용)

  • Kim, Yuna;Baik, You-sang;Jeong, Chang-hyun;Jang, Woo-chang
    • Journal of Korean Medical classics
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    • v.34 no.2
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    • pp.107-126
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    • 2021
  • Objectives : To discuss the therapeutic properties of Daoyin, and suggest ways to apply the Spleen Daoyin Method clinically. Methods : The therapeutic properties of Daoyin were examined in medical texts, after which the movements and effects of the Spleen Daoyin Method were analyzed. Based on relevant contents in the Donguibogam, symptoms and diseases for application of the Spleen Daoyin Method were studied to suggest further clinical application possibilities. Results & Conclusions : Daoyin manages the body by treating diseases, while keeping the Shen intact to manage the mind. In the case of the Five Zhang Daoyin Method, its therapeutic nature is clear as the target is focused on the Five Zhang. The Spleen Daoyin Method is mostly comprised of two movements that enable overall restoration and improvement of the Spleen function. Therefore, it could be applied in cases of Spleen-Stomach diseases where there is functional damage.

Implementation of the Aptitude Test System for People with Visual Impairment Supporting Web Accessibility (웹접근성을 지원하는 시각 장애인용 적성검사 시스템의 구현)

  • Ban, Chae-Hoon;Park, Hye-Jeon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.05a
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    • pp.191-194
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    • 2009
  • Vocational rehabilitation is defined as a process which helps people with disabilities to maintain life of non-disabled people and vocational assessment is a part of it. Traditionally, vocational assessment is performed through using of assessment tools, vocational counseling and so on. It is very efficient to apply vocational assessment to people with disabilities using the internet, but we should provide them with web accessibility. In this paper, we design and implement the aptitude test system for people with visual impairment supporting web accessibility. We develop the aptitude test system using the Holland Test which is the assessment tool of career guidance and counseling. We also show that the aptitude test system for people with visual impairment supports web accessibility more than previous Holland Test which is served in the internet.

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