• Journal of Chest Surgery
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• v.32 no.6
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• pp.518-524
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• 1999

Background: This study has proven the effect of modified ultrafiltration(MUF) performed after the cessation of cardiopulmonary bypass in pediatric patients who underwent open heart surgery. Material and Method: From Jan. to Dec. 1997, modified ultrafiltration was performed after cardiopulmonary bypass in 50 infants with cyanotic heart disease and the results were compared to the control group of 50 patients with cyanotic heart disease in whom modified ultrafiltration was not used. Changes of hematocrit, central venous pressure, systolic and diastolic pressure, heart rate and body weight were compared. Result: Age and body weight were not different(p=0.38, p=0.46). Disease categories were similar. Average filtering volume was 60.0$\pm$29.2cc/kg for 7.0$\pm$2.4minutes of filtration. Mean hematocrit after filtration(MUF=36.1%, control=26.4%, p=0.001) was higher in the MUF group. Systolic (p=0.0001) and diastolic blood pressure(p=0.0001) were observed to increase more and the central venous pressure(p=0.02) and the heart rate(p=0.02) were lower after filtration in the MUF group. Conclusion: This study demonstrated that modified ultrafiltration after cardiopulmonary bypass was a technically feasible option to improve the post-surgical course through the effective hemoconcentration, hemodynamic improvements, and body water control.

• Journal of agricultural medicine and community health
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• v.35 no.2
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• pp.165-176
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• 2010

Objectives: This study is to identify the effect of detraining on lipoprotein and body composition after 8 week calorie restriction and different level of aerobic exercise among obese middle-aged women. Methods: The 30 middle-aged women whose body fat were over 30% were randomly allocated into three groups of control, exercise group of 40% $VO_2$max level, and exercise group of 60% $VO_2$max level. All the participants were taught to record their calorie intake and restrict daily 500kcal intake. After eight-week exercise and daily 500kcal restriction, their body compositions and blood lipid levels were measured again. Results: The weight, BMI, body fat, total cholesterol, triglyceride, and LDL-cholesterol levels showed significant decreases after eight-week exercise and calorie restriction in the two exercise groups. However, detraining tended to increase them again after detraining of 4 weeks, and even more after 8 weeks. Conclusions: Detrainging after calorie restriction and exercise tended to increase levels of indices for body composition and lipoprotein among obese middle-aged women.

• Journal of the Korean Society of Food Science and Nutrition
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• v.38 no.1
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• pp.39-46
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• 2009

This study investigated the beneficial effects of crude saponins from soybean cake on body weight and glucose tolerance in high-fat (37% calories from fat) diet fed C57BL/6 mice. The mice were supplemented with three doses of saponins (0.5%, 1.0%, and 1.5%, wt/wt) and 1.0% Garcinia cambogia (wt/wt), positive control for 9 weeks. The body weight, visceral fat weight and epididymal adipocyte area were significantly reduced in the saponin supplemented groups in a dose dependent manner compared to the high-fat group. Saponins did not significantly affect food intake; however, cambogia significantly lowered food intake compared to the high-fat fed control group. The crude saponins from soybean cake supplement significantly lowered plasma leptin, triglyceride and total cholesterol levels, whereas they significantly elevated the fecal excretion of triglyceide in a dose dependent manner compared to the high-fat group. Cambogia did not affect the fecal excretion of lipid in the diet-induced obese mice. Supplementation of 1.5% saponin reduced the hepatic triglyceride content compared to the high-fat group. High-fat induced glucose intolerance with the elevation of blood glucose levels compared to the normal group; however, the saponins supplement significantly improved postprandial glucose levels. After 9 weeks of being fed a high-fat diet, the mice presented with significantly increased activities of hepatic fatty acid synthase and fatty acid ${\beta}$-oxidation; however, saponins and cambogia normalized these activities. These results indicate that saponins from soybean cake exhibit a potential anti-obesity effect and may prevent glucose intolerance by reducing body weight and plasma lipids, increasing fecal lipid excretion and regulating hepatic lipid metabolism in high-fat fed mice.

• Journal of KIISE:Computer Systems and Theory
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• v.33 no.3
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• pp.157-165
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• 2006

The change of external/internal factors of the cell rquires specific biological functions to maintain life. Such functions encourage particular genes to jnteract/regulate each other in multiple ways. Accordingly, we applied a linear decomposition model IFSA, which derives hidden variables, called the 'expression mode' that corresponds to the functions. To interpret gene interaction/regulation, we used a cross-correlation method given an expression mode. Linear decomposition models such as principal component analysis (PCA) and independent component analysis (ICA) were shown to be useful in analyzing high dimensional DNA microarray data, compared to clustering methods. These methods assume that gene expression is controlled by a linear combination of uncorrelated/indepdendent latent variables. However these methods have some difficulty in grouping similar patterns which are slightly time-delayed or asymmetric since only exactly matched Patterns are considered. In order to overcome this, we employ the (IFSA) method of [1] to locate phase- and shut-invariant features. Membership scoring functions play an important role to classify genes since linear decomposition models basically aim at data reduction not but at grouping data. We address a new function essential to the IFSA method. In this paper we stress that IFSA is useful in grouping functionally-related genes in the presence of time-shift and expression phase variance. Ultimately, we propose a new approach to investigate the multiple interaction information of genes.

• Korean Journal of Community Nutrition
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• v.15 no.1
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• pp.61-72
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• 2010

The purpose of this study was to evaluate the effect of a weight control program on anthropometric values, serum lipid profiles and nutrient intakes. The subjects of this study were 38 obese children (boy : 17, girl : 21) with obesity index over 120%. The weight control program for obese children included nutritional education (50 min) and exercise (50 min) for 10 weeks. The nutrition intakes of the children were surveyed before and after the weight control program by 24hr recall test. The BMI, R$\ddot{o}$hrer Index, Obesity Index, WHR (Waist - Hip ratio) and body fat(%) were significantly decreased after completion of the weight control program. The total cholesterol and HDL-cholesterol of subjects were significantly increased after the weight control program. Distribution of serum lipid profiles was slightly changed. The energy intakes were significantly decreased (p < 0.001). from 1760.8 kcal to 1435.2 kcal. In addition, the intakes of P, Zn, retinol, vitamin $B_1$, vitamin $B_2$, vitamin E and niacin were significantly decreased. while intakes of vitamin C and folate were increased. Calcium and folic acid were upper 25% of subjects, under EAR(Estimated Average Requirements) intake before the weight control program. The distribution of energy intakes was significantly changed into positive status; fat percentage was decreased 26.3% to 22.1% (p < 0.01). Carbohydrate was increased 58.6% to 61.2% (p < 0.05). Meal distribution of energy intakes was changed; calorie percentage from lunch significantly increased from 32.2% to 38.3%. Calorie percentage from snack significantly decreased from 17.7% to 13.5%. In conclusion, weight control program for 10 weeks is effective in obesity index and nutrient intakes although serum lipid values were a little changed.

• Journal of the Korean Society of Food Culture
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• v.24 no.6
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• pp.793-804
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• 2009

This study was conducted to investigate the change in the anthropometric values, biochemical index, nutritional knowledge, food habits and nutrient intakes in obese children after a weight control program. The subjects of the study were 22 obese children with an obesity index over 120%. The children that participated in this study took nutritional education for weight control along with exercise once a week. The weight control program was conducted for 10 weeks. The BMI, WHR (Waist-Hip ratio), body fat (%) significantly decreased at the end of the weight control program. Total cholesterol and LDL cholesterol were also significantly decreased. The nutritional knowledge scores and knowledge score about obesity were slightly improved. Energy intake significantly decreased from 1768 to 1421 kcal. Intake of Ca, Na, K, vitamin A, vitamin $B_6$, vitamin C and folate increased, while intakes of P, Zn, vitamin $B_1$, vitamin $B_2$, vitamin E and niacin decreased. The distribution of energy intake was significantly changed for the better. The percent fat consumed decreased from 26.5 to 19.7%. In addition, the distribution of energy intake in the meals was changed, where the percent calories consumed during lunch significantly increased from 31.4 to 40.1% and the calorie percentage consumed from snacks significantly decreased from 17.6 to 10.7%. In conclusion, the nutritional education in the weight control program, which was conducted for 10 weeks, was effective in improving the anthropometric values, biochemical index and nutrient intake although nutrition knowledge and eating behaviors only changed slightly. Thus, nutritional weight control programs for obese children should be continuously provided under the proper cooperation of a nutritional teacher at elementary schools.

• Proceedings of the KAIS Fall Conference
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• 2009.12a
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• pp.326-330
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• 2009

본 연구는 일반 성인남성과 직업군인의 건강형태 및 의료이용에 대해서 2005년도 국민건강 영양조사의 자료를 질병관리본부로부터 획득하여 분석하였고 그 결과를 보면 전체조사 대상자는 8,384명으로 21세~55세의 일반성인남성과 직업군인만을 선정하였으며, 직업군인은 76명, 일반 성인 남자는 8,308명이었다. 보건의식 행태 분포에서 보면 현재 흡연상태는 일반인에 비해 직업군인이 높고, 주관적 체격인식은 일반인의 경우 비만 또는 매우 비만이라 인지하는 비율이 직업군인에 비하여 높게 나타났지만, 실제로 지난 1년간 체중조절 여부는 일반인이 오히려 직업군인에 비해 높게 나타났다. 또한 직업군인의 보건의식 행태는 평균 연령(p<0.05)에서 통계적으로 유의한 차이가 있는 것으로 나타났다. 월간 침상와병일수는 직업군인이 상대적으로 높았으나 월간 결석, 결근일수는 오히려 낮게 나타났다. 더불어 월간 결석, 결근일수(p<0.05)는 통계적으로 유의한 차이를 나타났다. 연간 입원이용율은 일반인이 높았으며, 평균 재원일수, 건당 평균 입원기간은 일반인에 비해 직업군인이 길었다. 2주간 외래 이용율은 일반인이 17.2%, 직업군인이 21.6%로 직업 군인의 외래이용이 많았고, 평균 외래이용 횟수에서도 일반인이 1.92, 직업군인이 2.44로 직업군인이 많았다. 이용한 보건의료기관의 종류에서는 일반인은 의원급이, 직업군인은 병원급의 외래이용이 많았고 2주간 약국 이용율은 직업군인이 16.2%로 일반인 22.0% 에 비하여 낮았다. 연간 사고 및 중독 발생자율은 직업군인이 9.5로 일반인 7.9에 비하여 높게 나타 났으며, 사고 및 중독 발생횟수에서는 일반인이 직업군인에 비하여 높았다. 의도성별 분포(p<0.05), 주치료기관(p<0.05)은 통계적으로 유의한 차이가 나타났다. 본 연구를 통해 일반적 특성, 보건의식행태, 건강수준의 분석 및 일반적 특성을 보정한 상태에서 일반 성인남성과 직업군인의 보건의식 행태와 의료이용 분포를 비교 분석한 것으로 향후 직업군인의 건강 증진을 위한 효과적인 교육과 정책수립에 필요한 기초자료가 될 수 있을 것으로 기대해 본다.

• Journal of the Korean Society of Food Culture
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• v.10 no.5
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• pp.367-375
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• 1995

The difference between self-evaluated obesity and obesity index of RBW and BMI as well as attitude toward weight control were studied among college students in Chungnam area. The subjects of 307 students were randomly selected and asked to categorize their body shape into 5 groups and to record their body weight and height. We found that average RBW and BMI of the students were 95.7% and 20.6, respectively. By RBW, 30.6% of students belonged to underweight and severe-underweight groups whereas 14.0% overweight and obesity ones. The female students showed lower obesity indice than the male. Self-evaluated obesity seemed likely to overestimate their body shapes above RBW and BMI, which lead to high unsatisfactioin toward their body shape. The overestimation was profound in normal weighted female students up to 20%. Misunderstanding about their obesity, especially among female college students, should be corrected necessarily by proper nutrition counseling and nutrition education, unless malnutrition could be serious in college students.

• Journal of the Korean Society of Food Culture
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• v.30 no.1
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• pp.105-117
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• 2015

The purpose of this study was to compare weight control behaviour, eating habits, and health-related life habits according to degree of obesity among normal, overweight, and obese groups. Self-perception of weight and desire for weight control in males (p<0.001) and females (p<0.001) varied among the three groups. Reasons (p<0.001), experience (p<0.01), and method of weight control (p<0.05) were different among the three female groups, whereas males did not show any differences. Intake of nutritional supplements in the male obese group was higher compared to other groups (p<0.01), whereas eating habits were not significantly different among the three groups for both males and females. Food habits score for intake of fruits, milk, and yogurt were higher in females than males (p<0.001). Correlation coefficients of food habits score and anthropometric measurements showed that hip circumference was negative for intake of fruits in males, whereas RBW and BMI were positive for food combination, intake of bean products, and fishes in females (p<0.05). Frequency and fitting exercise in the obese female group were lower than in the other groups (p<0.01). Therefore, proper nutritional education for obese individuals is recommended proper self-perception of weight, good food habits, and regular exercise.

• Journal of Nutrition and Health
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• v.41 no.7
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• pp.634-664
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• 2008

This study investigated the effects of the nutrition education on body weight, visceral fat and diet quality in the postmenopausal women. The subjects (n = 101) were randomly divided into two groups: Nutrition education + Exercise (NEE) group (n = 51) and Exercise only (EO) group (n = 50). Nutrition education was consisted of counseling in portion control, food selection for low carbohydrate, high fiber food items and for the improvement in micronutrient intakes and diet quality. After 6 months, the reduction in the body weight and visceral fat area was significantly greater in the NEE than in the EO group. The NEE subjects were further divided into two groups according to the amount of visceral fat area reduction; high visceral fat area loss (HVL) group with a visceral fat area reduction 2.35% or greater and low visceral fat area loss (LVL) group with a reduction less than 2.35%. In the HVL group, the reduction in body weight, BMI, percent body fat, waist to hip ratio and visceral fat area was significantly greater than that in the LVL group. We observed a significant increase in the serum HDL-cholesterol level and a decrease in systolic blood pressure, fasting blood sucrose, total and LDL-cholesterol levels in the HVL group compared to the LVL group. The energyadjusted protein, fiber, calcium, vitamin $B_6$, vitamin C, vitamin E intakes were significantly increased in the HVL compared to LVL group. The index of nutritional quality (INQ) and mean adequacy ratio (MAR) were also increased in the HVL group compared to the LVL group. These results show that our nutrition education program was an effective intervention measure for the reduction of body weight and visceral fat, blood pressure, glucose and lipid levels in the blood and also for the improvement of nutrient intake and diet quality in postmenopausal women who are overweight.