• The Korean Journal of Mycology
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• v.18 no.4
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• pp.225-232
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• 1990

In order to find an useful condition under which the mutants defective in sexual development could be isolated, the effects of several cultural conditions on the developments of Aspergillus nidulans were examined. Among several conditions found to restrict the asexual sporulation but enhance the sexual process, the interference of aeration by sealing the plates with sealing film was the most useful one for the purpose of mutant isolation. Sealing at any time before 20 hours from inoculation prevented both sexual and asexual process. When the seal was removed after 24 hours, however, the mycelia developed only to sexual organs. Using this properity, the early morphogenic process of sexual development could be easily observed and a number of mutants that showed some defects in the process could be isolated. The mutants were divided into 3 groups, NSD (never in sexual development), BSD (block in sexual development) and ASD (abnormal in sexual development). NSD mutants never produced either the $H{\ddot{u}}lle$ cells or cleistothecia and some produced the asexual organs even when the aeration was restricted. BSD mutants were blocked in the process of $H{\ddot{u}}lle$ cell, cleistothecia, crozier, asci or ascospore formation. ASD mutants had defects in the amount of cleistothecia, time of cleistothecial maturation or color of ascospores.

• The Journal of the Korea Contents Association
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• v.19 no.4
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• pp.282-292
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• 2019

The purpose of this study was to investigate the relationship between self-esteem and differentiation of self, and to identify the degree of self-esteem and differentiation of self. Data were collected from 151 elementary school students using community child center. Factor analysis, reliability analysis, correlation analysis, regression analysis, and cluster analysis were performed. The results of the study are as follows: First, as a result of factor analysis, differentiation of self was classified into differentiation of internal mind, other's and self oriented. Self-esteem was classified into isolation, achievement, relation, and daunted. Second, regression analysis indicated that there was obvious relationship between self-esteem and the differentiation of self. Third, cluster analysis showed that 37.6% of children belonged to cluster 2 with achievement and relation patterns and self-oriented differentiation. Forty-three percent were belonged to cluster 1 with isolated and daunted self-esteem as well as internal mind and other's oriented differentiation. In cluster 3, 19.4% were belonged and their levels of self-esteem and the differentiation of self were very low. Findings indicate that for those children belonged to cluster 1 and 3, programs to raise the self-esteem of children and parental education are needed.

• Journal of Sasang Constitutional Medicine
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• v.8 no.1
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• pp.295-317
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• 1996

It is researched to elucidate the effects of Taeumjowuitang(TE,太陰調胃湯), Sibimikwanjungtang(SE, 十二味寬中湯) and Yangkeogsanwhatang(SY,凉膈散火湯) on the obesity induced by gold thioglucose and the differentiation and growth of preadipocyte 3T3-L1 in the mouse. The result were as follows: 1. TE,SE and SY extracts improved the blood level of transaminase in the obese mouse induced by gold thioglucose. 2. TE,SE and SY extracts inhibited the increase of liver fat and body fat in the obese mouse induced by gold thioglucose. 3. TE,SE and SY extracts inhibited the increase of body weight in the obese mouse induced by gold thioglucose. 4. TE,SE and SY extracts inhibited the growth of undifferentiate preadipocyte 3T3-L1. 5. TE,SE and SY extracts showed inhibitory effect on the differentiation of preadipocyte 3T3-L1. The above results suggest that the TE,SE and SY extracts may be used on the obesity induced by the overgrowth and differentiation of adipocyte, and the accumulation of fat in liver and body.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2000.11a
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• pp.111-114
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• 2000

종의 분화는 생명체의 다양성을 유지하며, 좀더 환경에 적합한 생명체를 탄생시킨다. 본 논문에서는 이러한 종의 분화 개념을 도입한다. 개체군의 각 개체들이 돌연변이를 통하여 자손을 생성하고, 그 중 일부가 분화하여 다음 세대의 개체를 이룬다. 각 개체들은 돌연변이에 의해 결정되는 일정한 해밍 공간 내외를 탐색공간으로 하고, 분화를 통하여 유효한 탐색공간을 점차 넓혀 탐색공간 전체에 대한 효율적인 탐색을 수행한다. 돌연변이를 통한 진화 방법으로 진화 하드웨어에 적용할 경우 내부구조의 변경이 적어 빠른 탐색효과를 갖을 수 있다. 제안된 알고리즘을 2개의 최적화 문제에 적용하여 그 유용성을 확인한다.

• Proceedings of the Korean Society for Bio-Environment Control Conference
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• 2001.11a
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• pp.102-115
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• 2001

국내 분화류의 생산면적은 2000년 현재 1,036.2ha이며 생산량은 연간 282,656천분, 그리고 생산액은 연간 268,498,990천원으로 추산되고 있다(2000년 화훼재배현황, 농림부). 이와 같은 국내 분화재배면적이 증가함에 따라 다양한 화종의 분화가 재배되고 있으며 화종에 따른 관수방법, 이용상토, 양액농도, 시비방법 등에 대한 많은 연구가 이루어지고 있다(Lieth and Burger, 1989). (중략)

• Proceedings of the Korean Society of Grassland Science Conference
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• 1999.06a
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• pp.94.1-94
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• 1999

5품종의 오차드그라스 종자로부터 직접 캘러스를 유도하고, 형성된 캘러스로부터 식물체를 재분화하는 조건을 확립하였다. 공시품종중 합성 19호가 캘러스 유도 및 재분화에서 가장 우수한 것으로 판명되었으며, SH, MS, N6 배지중에서 캘러스 유도시에는 MS 배지가, 재분화시에는 N6 배지가 유리한 것으로 나타났다.(중략)

• Proceedings of the Korean Society of Grassland Science Conference
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• 1999.06a
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• pp.72-73
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• 1999

Perennial ryegrass의 종자유래 캘러스 및 조직 절편체로부터 식물체 재분화에 적합한 조건을 조사하였다. 종자유래 캘러스로부터 식물체 재분화 조건을 확립하기 위하여, 품종, 배지 및 생장조절물질의 조성 등에 따른 재분화율을 조사하였다. Reveille과 Modus의 품종간 비교에서 종자로부터 형성된 캘러스 생체중은 Reveille이 2,4-D 10mg/$\ell$에서 가장 좋았으며, MS배지가 SH, B5배지보다 더 좋았다.(중략)

• Proceedings of the Korean Society of Grassland Science Conference
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• 1999.06a
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• pp.93-93
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• 1999

4품종의 알팔파 (Medicago sativa L.) 종자로부터 직접 캘러스를 유도하고, 형성된 캘러스로부터 식물체를 재분화하는 조건을 확립하였다. 공시품종중 "Vernal" 품종이 캘러스 유도 및 재분화에서 가장 우수한 것으로 판명되었으며, SH(Schenk and Hildebrandt), MS (Murashige and Skoog), N6 (Chu) 배지중에서 SH 배지가 캘러스 유도와 재분화시에 모두 유리한 것으로 나타났다. 캘러스 유도 및 증식시에는 2,4-D를 3mg/$\ell$ 농도로 첨가한 SH-3 배지에서 가장 효율이 좋았으며, kinetin을 첨가하거나 kinetin의 농도가 높을수록 캘러스 형성 정도는 급격히 저하되었다.(중략)저하되었다.(중략)

• Proceedings of the Korean Information Science Society Conference
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• 2002.10d
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• pp.238-240
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• 2002

진화 가능한 하드웨어의 개발은 유전자 알고리즘의 새로운 가능성을 열어주었고 이에 적합한 다양한 방법이 제시되어 왔다. 하지만 일반적인 유전자 알고리즘으로는 Genetic drift가 생기거나 지역해에 빠지는 등 한계가 있기 때문에 이를 해결하기 위한 방안으로 종분화 알고리즘이 도입되고 있다. 현재까지 다양한 종분화 알고리즘이 소개되었는데 이들은 이전의 알고리즘과 비교하였을 때 높은 다양성을 유지하면서 더 좋은 해를 찾아낸다. 이 논문에서는 진화 하드웨어상에서 이러한 종분화 알고리즘들의 장단점 및 특징을 여러 비교기준을 통해 제시한다. 실험결과 Deterministic Crowding과 Struggle GA가 가장 좋은 성능을 나타내었다.

• Journal of Life Science
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• v.22 no.4
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• pp.447-455
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• 2012

Akt plays an important role in a variety of cellular physiologies such as growth, proliferation, and differentiation. In skeletal muscle, Akt has been implicated in regulating regeneration, hypertrophy, and atrophy. In this study, the role of Akt has been examined during skeletal muscle differentiation. Culturing C2C12 myoblasts under low serum (1% horse serum) and high density converted cell morphology from a round shape to an elongated and multi-nucleated shape. Morphological changes were initiated from day 2 of differentiation. In addition, the expression of both myogenin G and myogenin D was elevated from day 2 of differentiation. Skeletal muscle differentiation was abolished by silencing Akt1 or Akt2, but was significantly enhanced by the over-expression of either Akt1 or Akt2. The activation of Akt was observed from day 2 of differentiation and disappeared after day 7. The expression of kruppel-like factor 4 was observed from day 6 of differentiation. Moreover, this expression was blocked in cells silencing either Akt1 or Akt2. In addition, the promoter activity of kruppel-like factor 4 was significantly reduced in cells silencing Akt1 or Akt2. These results suggest that Akt regulates skeletal muscle differentiation through the regulation of kruppel-like factor 4 expression.