• Applied Chemistry for Engineering
• /
• v.24 no.1
• /
• pp.1-9
• /
• 2013

As the medical paradigm is changing from disease treatment to disease prevention and an early diagonosis, the demand to develop techniques for the detection of minute concentrations of biomolecules is increasing. Among the various techniques to sense the minute concentration of biomolecules, the biosensors utilizing the matured semiconductor techniques are presented here. To understand such biosensors, the structure and working principle of a MOSFET (Metal-oxide-semiconductor field-effect transistor) which is the basic semiconductor device is firstly introduced, and then the ISFET (Ion sensitive FET), BioFET (Biologically modified FET), Nanowire FET, and IFET (Ionic FET) are introduced, and their applications to biomedical fields are discussed.

• Korean Chemical Engineering Research
• /
• v.58 no.2
• /
• pp.230-234
• /
• 2020

A system that uses deep-learning techniques to predict properties from molecular structures has been developed to apply to chemical, biological and material studies. Based on the database where molecular structure and property information are accumulated, a deep-learning model looking for the relationship between the structure and the property can eventually provide a property prediction for the new molecular structure. In addition, experiments on the actual properties of the selected molecular structure will be carried out in parallel to carry out continuous verification and model updates. This allows for the screening of high-quality molecular structures from large quantities of molecular structures within a short period of time, and increases the efficiency and success rate of research. In this paper, we would like to introduce the overall composition of the materiality prediction system using deep-learning and the cases applied in the actual excavation of new structures in LG Chem.

• Proceedings of the Korea Contents Association Conference
• /
• 2007.11a
• /
• pp.539-542
• /
• 2007

After introducing some experiment methods including immunoprecipitation and yeast two-hybrid screening, the pool of molecular interaction data is growing fast and databases are produced dramatically. But it is difficult to apply the information to molecular kinetic studies for understanding disease. In this paper, we developed a program that can browse and visualize interactions of cellular molecules using importing heterogeneous external data file. This program support 3D view to navigate and understand more easily and making a signal transduction model that user wants and simulating function to research the model. It was tested for signal transduction of chmotaxis in bacteria.

• Journal of the Microelectronics and Packaging Society
• /
• v.30 no.2
• /
• pp.13-20
• /
• 2023

The process of microelectromechanical system (MEMS) fabrication involves surface treatment to impart functionality to the device. Such surface treatment method is the self-assembled monolayer (SAM) technique, which modifies and functionalizes the surface of MEMS components with organic molecule monolayer, possessing a precisely controllable strength that depends on immersion time and solution concentration. These monolayers spontaneously adsorb on polymeric substrates or metal/ceramic components offering high precision at the nanoscale and modifying surface properties. SAM technology has been utilized in various fields, such as tribological property control, mass-production lithography, and ultrasensitive organic/biomolecular sensor applications. This paper provides an overview of the development and application of SAM technology in various fields.

• Membrane Journal
• /
• v.26 no.5
• /
• pp.329-336
• /
• 2016

Proton exchange membrane (PEM) is one of the key components of membrane-electrode assembly (MEA), which plays important role in fuel cell performance together with catalysts. It is widely accepted that water channel morphology inside PEMs as a proton pathway significantly affects the PEM performance. Molecular dynamics (MD) simulations are a very useful tool to understand molecular and atomic structures of materials, so that many related researches are currently being studied. In this paper, we summarize the current research trend in MD simulations, present which properties can be characterized, and finally introduce the usefulness of MD simulations to the researchers for proton exchange membranes.

• Applied Chemistry for Engineering
• /
• v.2 no.4
• /
• pp.311-329
• /
• 1991

Electrochemical behavior of surface active Osmium bipyridine complex adsorbed in a monomolecular layer on tin oxide electrodes by the Langmuir-Blodgett method was studied. Theoretical equation of cyclic voltammetry of electrode reactions for redox species adsorbed as monolayer form was discussed by reversible and quasi-reversible waves. The film was transferred onto the $SnO_2$ electrode surface and then amounts of charge on the electrode were measured in the technique of cyclic voltammetry. The electron transfer mediation of these monolayer with $Fe^{2+}$, TEMPOL and others were studied. And the cyclic voltammetry were simulated by taking into account the interaction parameters. From these values, we found it possible to fit almost all measured cyclic voltammograms with these parameters. The recent works and directions using LB method were introduced with various applicable field.

• Membrane Journal
• /
• v.24 no.5
• /
• pp.341-349
• /
• 2014

Molecular dynamics (MD) computer simulation is a very useful tool to calculate the trajectory and velocity of particles (generally, atoms), and thus to analyze the various structures and kinetic properties of atoms and molecules. For gas separation membranes, MD has been widely used for structure analysis of polymers such as free volume analysis and conformation search, and for the study of gas transport behavior such as permeability and diffusivity. In this paper, general methodology how to apply MD on gas separation membranes will be described and various related researches will be introduced.

• Membrane Journal
• /
• v.29 no.4
• /
• pp.202-215
• /
• 2019

Molecular sieve membranes separate molecules based on their size and/or shape and have been of high interest, due to their potentially high energy efficiency and high selectivity. Zeolite MFI membrane is one of the most-studied molecular sieve membranes and has affected following studies on other molecular sieve membranes. This review discusses the technical developments on the control of morphology, microstructure, and defect of MFI membranes, which have significantly improved xylene isomer separation performances. These include crystal morphology control, effective secondary growth, seed coating method, crystal orientation control, heteroatom doping, and defect healing method.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2012.08a
• /
• pp.204-204
• /
• 2012

고용량/대면적/초정밀 제품을 지향하는 개발추세에 따라 고진공 펌프중 하나인 크라이오펌프의 활용도가 크게 증가하며 첨단 공정장비인 LCD 분야 등과 같이 수소 분자와 물 분자 등의 배기가 중요한 응용분야에 크라이오펌프의 수요가 대부분을 차지하고 있다. 그러나 크라이오펌프의 운전성능에 대한 표준절차에 따른 실질적인 측정은 빈약한 편이다. 이에 크라이오펌프의 종합 성능평가 기술 개발을 통해 실질적인 크라이오펌프의 운전성능을 제시하고자 한다. 본 연구에서는 고진공 펌프중의 하나인 크라이오펌프의 종합 성능평가 표준절차 및 표준시스템에 대해 소개하며, 상용화 제품에 대한 각 회사에서 제시하고 있는 성능지표에 대해 실질적인 측정에 대한 비교분석을 하고자 한다. 또한 가장 중용한 성능지표 중의 하나인 배기속도 측정에 대해 물리적 특징과 구조적 오차에 대한 보정 식들을 제공하고자 한다.

• Journal of the KSME
• /
• v.55 no.7
• /
• pp.32-36
• /
• 2015

최근 화석 연료의 과다 사용에 따른 에너지 자원 고갈 및 환경오염에 대한 우려가 증가함에 따라 비화석연료 기반의 재생가능하고 지속가능하며, 환경친화성이 높은 에너지에 대한 관심이 급증하고 있다. 농산폐기물, 폐목재, 에너지작물, 도시고형폐기물, 미세조류, 거대조류 등 육상 및 해상에서 발생하는 바이오매스는 재생가능한 에너지원으로서 화석원료와는 달리 사용 후 발생하는 이산화탄소를 다시 흡수하는 탄소중립(carbon-nutral)의 특성을 갖고 있어 전세계적으로 많은 주목을 받고 있다. 바이오연료 중 당질계원료를 이용하는 바이오에탄올 및 식물성유지를 이용하는 바이오디젤은 현재 상업적인 생산이 이루어지고 있으나, 이들 1세대 바이오연료는 식량자원과의 경쟁이라는 원천적인 한계를 가지고 있고, 분자구조식에 산소를 포함하고 있기 때문에 기존 화석원료에서 출발하는 가솔린, 항공유 및 디젤과 비교하였을 때 에너지 함량이 낮은 단점이 있다. 따라서 기존 1세대 바이오연료에서 탈피하여, 식량자원과 경쟁이 없으며, 또한 분자구조식에 산소를 적게 포함하거나 아예 포함하지 않는 바이오연료("drop-in" 바이오연료) 생산에 많은 관심이 집중되고 있다. 이 글에서는 최근 그린공정으로 대표되는 초임계 유체를 이용한 "drop-in" 바이오연료를 제조하기 위한 바이오매스 액화의 기술동향을 소개하고자 한다.