• Microbiology and Biotechnology Letters
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• v.40 no.2
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• pp.157-162
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• 2012

In this study, we have for the first time applied increased surface area fractional precipitation in order to decrease the particle size of the anticancer agent paclitaxel from plant cell cultures. When compared with the case where no surface area increasing material was employed, the addition of ion exchange resin as a surface area increasing material resulted in a considerable decrease in the size of the paclitaxel precipitate. When ion exchange resin was used, the paclitaxel particles were four to five times smaller, having less than a 20 ${\mu}m$ radius, than those obtained in the absence of ion exchange resin. This is presumably because the growth of paclitaxel particles was impeded by the addition of ion exchange resin. The size of the paclitaxel precipitate also depended on the material used to increase the surface area, a result considered to be due to differences in the affinity between the particular ion exchange resin used and the paclitaxel particles. The yield of paclitaxel was significantly improved when ion exchange resin was used as a material to increase surface area. Paclitaxel, with a reduced particle size due to the addition of a surface area increasing material during the fractional precipitation process, is believed to be particularly useful for practical applications of the drug.

• Journal of Korean Medical classics
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• v.31 no.1
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• pp.45-55
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• 2018

Objectives : This study was conducted to infer the effect of superficies-resolveing herbs by analyzing effect terms which have extracted and refined, based on four temperatures and five tastes. Methods : Firstly, temperatures, tastes and effect terms were extracted from the 27 kinds of superficies-resolving herbs written in Herbology. Then, each effect terms was divided into single meaning term and refined as typical term, using the inclusive effect terms I established. After that, herbs were grouped by tastes and found the effect terms which are mentioned most frequently. Results & Conclusions : All the superficies-resolving herbs can have wind-dispelling effect and superficies-resolving effect, except Bulpleuri Radix. This herb is able to has just the wind-dispelling effect. And it's more appropriate to categorize Bulpleuri Radix to heat-clearing herb group than superficies-resolving herb group, considering its several, distinctly cold characteristics. Some effects are concentrated to wind-cold-dispersing herb group and others to wind-heat-dispersing herb group. Each tastes has its own representative effect group.

• Journal of KIISE:Software and Applications
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• v.30 no.3_4
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• pp.372-378
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• 2003

Limitations on the linear discriminant analysis (LDA) for face rerognition, such as the loss of generalization and the computational infeasibility, are addressed and illustrated for a small number of samples. The principal component analysis (PCA) followed by the LDA mapping may be an alternative that ran overcome these limitations. We also show that any schemes based on either mappings or template matching are vulnerable to image variations due to rotation, translation, facial expressions, or local illumination conditions. This entails the importance of a proper preprocessing that can compensate for such variations. A simple template matching, when combined with the geometrically correlated feature-based detection as a preprocessing, is shown to outperform mapping techniques in terms of both the accuracy and the robustness to image variations.

• KIISE Transactions on Computing Practices
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• v.20 no.11
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• pp.586-591
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• 2014

In recent years, we can access to video contents anywhere and at any time. Therefore distributed video is easily copied, transformed and republished. Since it brings copyright problem, similarity/duplicate detection and measurement is essential to identify the excessive content duplication. In this paper, we analysed various discernment of video which has been transformed with various ways using MPEG-7 Video Signature. MPEG-7 Video Signature, one of video copy detection algorithms, is block based abstraction. Thus we assume Video Signature is weak for spatial transform. The experiments show that MPEG-7 Video Signature is very weak for spatial transform which could occur general as we have assumed.

• Journal of the Korean Data and Information Science Society
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• v.26 no.1
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• pp.31-39
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• 2015

This paper deals with a method for estimating variance components on the basis of projections under the assumption of random effects model. It discusses how to use projections for getting sums of squares to estimate variance components. The use of projections makes the vector subspace generated by the model matrix to be decomposed into subspaces that are orthogonal each other. To partition the vector space by the model matrix stepwise procedure is used. It is shown that the suggested method is useful for obtaining Type I sum of squares requisite for the ANOVA method.

• The Journal of the Acoustical Society of Korea
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• v.13 no.5
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• pp.24-31
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• 1994

In this paper, we study continuous speech recognition of Korean language using acoustic models of word juncture coarticulation. To alleviate the performance degradation due to coarticulation problems, we use context-dependent units that model inter-word transitions in addition to intra-word transitions. In all cases the initial phone of each word has to be specified for each possible final phone of the previous word similarly for the final phone of each word. To improve the robustness of the HMM parameters, the covariance matrix is smoothed. We also use position-dependent units to improve the discriminative power between units. Simulation results show that when the improved models of word juncture coarticulation are used. the recognition performance is considerably improved compared to the baseline system using only intra-word units.

• Journal of Institute of Control, Robotics and Systems
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• v.13 no.7
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• pp.616-623
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• 2007

A dual micro gas sensor array was fabricated using nano sized $SnO_2$ thin films which had good sensitivities to CO and combustible gases, or $H_2S$ gas for air quality sensors in automobile. The already existed air quality sensor detects oxidizing gases and reducing gases, the air quality sensor(AQS), located near the fresh air inlet detected the harmful gases, the fresh air inlet door/ventilation flap was closed to reduce the amount of pollution entering the vehicle cabin through HVAC(heating, ventilating, and air conditioning) system. In this study, to make $SnO_2$ thin film AQS sensor, thin tin metal layer between 1000 and $2000{\AA}$ thick was oxidized between 600 and $800^{\circ}C$ by thermal oxidation. The gas sensing layers such as $SnO_2$, $SnO_2$(pt) and $SnO_2$(+CuO) were patterned by metal shadow mask for simple fabrication process on the silicon substrate. The micro gas sensors with $SnO_2$(+Pt) and $SnO_2$(CuO) showed good selectivity to CO gas among reducing gases and good sensitivity to $H_2S$ that is main component of bad odor, separately.

• The Journal of the Petrological Society of Korea
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• v.4 no.2
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• pp.124-133
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• 1995

Oxygen isotope compositions have been determined for the granitic and the related rocks from the Wolf River Ratholith, Wisconsin in U.S.A. Plutons which belong to the differentiation trend are almost identical in oxygen isotope fractionation, and plutons of undifferential sequences also show oxygen isotope compositions similar to each other, which show little isotope fractionations at high temperature range. In oxygen osotope composition, the country rocks (the Penokean plutonic rocks), which is higher by 1~2 permil than the batholith are improbable source of the batholith. However, the assimilation of parent magma of lower ${\delta}^{18}O$ values than the batholith with the Penokean plutonic rocks might have produced the batholith.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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• 2002.09a
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• pp.331-334
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• 2002

탄산수내 REEs의 함량과 거동특성을 알아보기 위해 암석시료, 탄산수 및 침전물에 대한 REEs 분석을 실시하였다. 탄산수가 산출되는 인접지에서 채취한 암석시료들은 물의 유형에 따라 큰 농도변화를 보여주지 않으며, 대체적으로 LREEs가 부화된 특성을 보여주고 있다. 유형에 따른 탄산수의 REEs 농도변화는 서로 상이한데, Na-HCO$_3$ 유형은 강한 HREE의 부화를 보여주지만, Ca-HCO$_3$ 유형은 HREE의 부화를 보여주지 않고 감소하는 경향을 보이며, 화학적으로 중간 유형에 속하는 Ca-Na-HCO$_3$ 유형 탄산수는 Eu을 제외하고는 전체적으로 flat한 분포를 보여준다. 탄산수에서 침전된 침전물과 침전물을 제거한 물의 REE의 유형은 침전물이 발생되기 전의 탄산수와 유사한 경향을 보이지만, 침전물의 발생으로 인한 특징적이고 강한 anomalies를 보여준다. 침전된 침전물의 REEs 특성은 침전물이 발생되기 전의 원 탄산수와 거의 유사한 분포특성을 보여준다. 반면에 침전물을 제거한 탄산수에서는 탄산염침전물의 침전과 연관되어 매우 강한 Eu anomalies를 보여주며, 대체적으로 HREE가 부화된 특성을 보여주었다. 탄산수내 가장 우세한 REE 종은 CO$_3$$^{2-}$ 종이며, CO$_3$$^{2-}$ 복합체 때문에 REEs의 분별작용 (HREE의 부화)이 일어나는 것으로 판단되 었다.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.35C no.6
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• pp.88-98
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• 1998

Subspace classifier is a popular pattern recognition method based on Karhunen-Loeve transform. This classifier describes a high dimensional pattern by using a reduced dimensional subspace. Because of the loss of information induced by dimensionality reduction, however, a subspace classifier sometimes shows unsatisfactory recognition performance to the patterns having quite similar principal components each other. In this paper, we propose the use of multiple novelty neural network classifiers constructed on novelty vectors to adopt minor components usually ignored and present a method of improving recognition performance through combining those with the subspace classifier. We develop the proposed classifier on handwritten numeral database and analyze its properties. Our proposed classifier shows better recognition performance compared with other classifiers, though it requires more weight links.