• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.225-233
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• 2005

Purpose : Hysterectomy is the most common gynecologic operation in women. Recent research has been directed towards understanding the symptoms after hysterectomy. But the study for treating them was rarely investigated. The purpose of this study was to report a case associated with treatment of the post-hysterectomy syndrome. Methods : A 52-year-old woman, who suffered from headache, dizziness, indigestion, lumbargo, insomnia, hyposthenia et al after total abdominal hysterectomy (TAH), was enrolled in this study. She received oriental treatments such as herbal medicine, acupuncture, moxibustion and dry cupping therapy for 8 days. Results : The symptoms after hysterectomy were markedly reduced by oriental treatments. Conclusion : The present study suggests that oriental treatments have a significant effect on the post-hysterectomy syndrome.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.215-224
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• 2005

Purpose : Endometrial hyperplasia(EH) is an abnormal proliferation of the glandular component of the endometrium. And also EH is relateted to endometrial carcinoma clinically. Hysterectomy is the common treatment for EH patients in western medicine, but this treatment is the invasive treatment for women. The purpose of this study is to report the effect of oriental treatment for an abnormal uterine bleeding owing to endometrial hyperplasia. Methods : This study is about metrorrhagia owing to EH for three years. This report is performed to observe medication of Guichulpajing-tang(歸朮破?湯) diagnosed as blood stasis in oriental medicine view. Results : The uterine bleeding of the EH was reduced gradually during first menstual cycle and was not repeated. The uterine bleeding disappered from the next menstual cycle. Furthermore, the BBT has been stable during 2 menstual cycles and endometrial thickness has been thined remarkably by pelvic sonogram. Conclusion : This case showed successful oriental herbal medication for EH and further study will be investigated in oriental medicine for treatment of EH completely.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.184-191
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• 2005

Purpose : To evaluate the effect of herb-medicine on seminal parameters in male infertility patients. Methods : 25 patients were enrolled in this study. They were taken herb-medicine three times a day after meals for 2-5months. Semen analysis or CASA were taken on baseline and post-treatment. Results : The result were as follows : (1) No statistical differences in seminal volume were found. (2) The mean${\pm}$SD of sperm concentration was increased from $51.39{\pm}37.80{\times}10^6$ to $75.99{\pm}50.34{\times}10^6/ml$ alter treatment(P<0.05). (3) The mean${\pm}$SD of motility was increased from 20.22${\pm}$10.75% to 34.02${\pm}$21.36% after treatment(p<0.01). Conclusion : Herb-medicine can be effective on male infertility.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.127-138
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• 2005

Purpose : This study was designed to establish safety and efficacy of using herbal medicine in pregnancy and to investigate patient's treatment satisfaction. Methods : We investigated general pregnancy outcomes of twenty-five gynecological outpatients who visited Dongguk univ. Kangnam Oriental Hospital, from July 1, 2002 through December 31, 2004 and have taken herbal medicine in pregnancy. Additionally we investigated newborn's growth status and patient's treatment satisfaction. Results : The rate of normal delivery of patients used herbal medicine for diseases that possibility of abortion is not high was 100% and there was no malformation in normally delivered 21 cases. Most of Newborn's growth status was normal and the average score of patient's satisfaction was 3.5(absolutely satisfied=5). Conclusion : The results of this study show safety and efficacy of using herbal medicine in pregnancy. And In the future, It is thought that more exactly constructed clinical survey need to be carried out.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.77-91
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• 2005

Purpose : Trichosanthis Radix is traditional medical herb which has been shown to inhibit tumor cell proliferation. In this study, the effects of Trichosanthis Radix extract were investigated on inducing growth inhibition and apoptosis of human uterine cervical carcinoma cells. Methods : Human uterine cervical carcinoma cells line, ME-180, was used for the study. The cells were treated with varying concentrations of Trichosanthis Radix extract. Cell growth and inhibitory rate were measured by MTT assay. Apoptosis induction was detected by fluorescence microscopy, DNA ladder formation and flow cytometry. Results : Trichosanthis Radix extract inhibited the growth of human uterine cervical carcinoma cells in a dose-dependent manner. It induced ME-180 cells to undergo apoptosis including fragmented nuclei and nucleosome-sized DNA fragmentation. Flow cytometric analysis showed the increasing rate of apoptotic cells by Trichosanthis Radix extract. Reduction of mitochondrial membrane potential and increase in caspase-3 activity and were found in ME-180 cells treated with Trichosanthis Radix extract. Conclusion : Our data suggest that Trichosanthis Radix extract inhibit the growth and proliferation of ME-180 cells by apoptotic induction and facilitates its activity via caspase-3 activation initiated by depolarization of mitochondria.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.250-257
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• 2005

Purpose : This study was designed to evaluate the effects of oriental medicine therapy on a patient of metrorrhagia and metrostaxis with endometrial polyp. Methods : The clinical data was analyzed on a patient of metrorrhagia and metrostaxis with endometrial polyp whose main symptoms were dysfunctional uterine bleeding. A 27-year-old female who had been treated hormone replacement therapy for dysfunctional uterine bleeding at a obstetrics and gynecology became worse, so refused any more hormone replacement therapy and visited Dongsin university oriental hospital. The patient was admitted to the obstetrics and gynecology department of Dongsin university Oriental Medical Hospital, on Febrary 23, 2004 and remained until Apri 11, 2005. we treated the patient with a herb-medication, acupunture therapy, moxa therapy and etc. Results : After treatment, improvement was seen in dysfunctional uterine bleeding, generalized weakness. Conclusion : The study suggests that oriental medicine therapy is significantly effective in the treatment of metrorrhagia and metrostaxis with endometrial polyp.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.242-249
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• 2005

Purpose : The purpose of this paper is to report the effect of oriental medicine to primary infertility caused by uterus unicornis. Methods : The patient in this case, 30 years-old female was treated with herb medication(Sosihotang, Gyejibokryeonghwan) for one month. Before oriental treatment, she had been diagnosed as primary infertility caused by uterus unicornis in Samsung Cheil Hospital and treated medication and injection for IUI(intrauterine insemination) in 2 times. But she had failed in gestation. Results : After taking herb medication she became pregnant. Conclusion : According to this result, we concluded that herb medication could improve fertility rate. After this paper, further study and clinical approach based on oriental medicine will be needed about infertility caused by uterus unicornis.

• The Journal of Korean Obstetrics and Gynecology
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• v.29 no.4
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• pp.1-12
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• 2016

Objectives: The purpose of this study is to analyze the correlation between the pulse energy and hot flush in women who complain of climacteric syndrome. Methods: We analyzed the values of pulse energy on 78 of perimenopausal and postmenopausal women. The symptoms of patients were assessed by Kupperman’s index (KI) and Menopause Rating Scale (MRS). Statistical analysis was performed by Spearman correlation coefficient and student T-test, using SPSS 18.0 for window program. Results: The results were as follows. 1. There were no statistically significant relation between pulse energy of left Cheok subtracted from left Chon and KI, MRS hot flush score. 2. When divided depending on MRS hot flush score, There were no statistically significant differences on pulse energy. Conclusions: The results suggest that there is no correlation between hot flush score and pulse energy.

• The Journal of Korean Obstetrics and Gynecology
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• v.29 no.4
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• pp.57-68
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• 2016

Objectives: This paper aims to report the effects of Korean medical treatment on a patient who underwent abdominal surgery with hyperthermic intraperitoneal chemotherapy for ovarian cancer. Methods: An ovarian cancer patient underwent abdominal surgery and got Korean medical treatment during 7-day hospitalization. About 2 years later, with metastasis to the lymph nodes detected, she had abdominal surgery with hyperthermic intraperitoneal chemotherapy and got Korean medical treatment during 10-day hospitalization. The treatment included herbal medicine and acupuncture. Numerical Rating Scale (NRS) of symptoms was measured every morning. Results: After the treatment, sequela following surgery decreased, and general conditions improved. During 1st and 2nd hospitalization, NRS of general weakness, heartburn and dorsal chill significantly decreased (10 to 5, 10 to 5 and 10 to 2, respectively) while edema in both legs remained the same. Conclusions: This case shows that Korean medical treatment is effective for a patient who underwent abdominal surgery with hyperthermic intraperitoneal chemotherapy for ovarian cancer.

• The Journal of Korean Obstetrics and Gynecology
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• v.29 no.4
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• pp.69-79
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• 2016

Objectives: This study aims to report the effect of Korean medicine treatments on a patient with secondary dysmenorrhea caused by Herlyn-Werner-Wunderlich Syndrome (HWWS). Methods: We treated the patient who had secondary dysmenorrhea caused by HWWS, with acupuncture, herbal medicines, pharmacopuncture and hyperthermia therapy at ⃝⃝Hospital of Korean Medicine from July 9th 2016 to September 8th 2016. We evaluated changes of symptoms by Visual analog scale score (VAS), Multidimensional verbal rating scale (MVRS) and Verbal rating scale (VRS). Results: After treatments, the clinical symptoms such as dysmenorrhea (lower abdominal pain & lower back pain), lower abdominal fullness were significantly improved, VAS was decreased, but the improvement of scores on MVRS, VRS were unclear. Conclusions: This case report shows that Korean medical treatment is effective to treat secondary dysmenorrhea caused by HWWS.