• Journal of Nutrition and Health
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• v.48 no.2
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• pp.149-156
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• 2015

Purpose: This study examined the effects of combined intervention of isoflavones and exercise on bone mineral density, bone mineral content, and biochemical bone markers. Methods: Forty rats were divided into four groups; Control, Isoflavones (IF), Isoflavones + Running (IFR), and Isoflavones + Swimming (IFS). All of the rats in this study were fed an experimental diet and deionized water ad libitum for nine weeks. Bone mineral density (BMD) and bone mineral content (BMC) were estimated using PIXImus (GE Lunar Co, Wisconsin.) in spine and femur nine weeks after feeding or training. Results: The combined intervention did not affect weight gain, mean food intake, or food efficiency ratio. The serum concentrations of ALP and osteocalcin were not significantly different by combined intervention. The urinary DPD crosslinks values were not significantly different by combined intervention. There were no significant differences in serum PTH, calcitonin, and estradiol among all groups. Spine BMD, spine BMC and femur BMC were not significantly different by combined intervention. However, femur BMD was significantly higher in the IFR group than in the control group. Compared with the control group, spine BMD, spine BMC, and femur BMD per weight were markedly increased in the isoflavones supplementation and combined intervention group. In addition, femur BMC per weight was significantly higher in the IFS group than in the control group. Compared with the isoflavones supplemented group, BMD and BMC were not significantly different by combined intervention. Conclusion: It can be concluded that isoflavones supplementation or combined intervention of isoflavone and exercise had a beneficial effect on spine and femur peak bone mass in growing female rats.

• KSBB Journal
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• v.19 no.2
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• pp.113-117
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• 2004

The effect of ultrasonification on immuno-stimulatory activities of the extracts from Ephedra sinica Stapf and Rubus coreanus Miq. was observed by the growth of human immune cells. The extraction yields from water extracts and water extract with ultrasonification at 40$^{\circ}C$, 60$^{\circ}C$ and 100$^{\circ}C$ were compared. The highest yield was observed enhancement ratio 2.34% in the extract at 40$^{\circ}C$ with ultrasonification. The growth of human T-cell was increased up to 13.8${\times}$10$^4$ viable cells/$m\ell$ in adding 1.0 g/L of the ultrasonification extracts. The treated extracts increased the specific secretion of TNF-${\alpha}$ up to 10.5${\times}$10$\^$-4/ pg/cell. It was suggested that of the extracts on water the extraction yield with ultrasonification compared improved the extraction with ultrasonification of low than.

• Journal of Practical Engineering Education
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• v.12 no.2
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• pp.321-329
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• 2020

Most of the curricula of higher educational institutions, including universities, have been operated on a theoretical basis, and as a result, the academic talents have been mismatched with the competencies of industrial demand. Since 2015, the government project called "IPP-type Work and Learning Dual Program(WLDP)" is supporting four-year universities to minimize the academic talents mismatch. The purpose of the project is to improve the working ability of students by linking IPP with WLDP. However, the outcome of linking IPP to WLDP has been frustrating so far. In this study, "WLDP coupled with IPP" is proposed to reduce the perception gap between students and companies. In the suggested progress, student performs IPP first and WLDP second. Two examples have shown that the suggestion can be a quite effective process in matching student with the company.

• Journal of Practical Engineering Education
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• v.15 no.1
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• pp.199-208
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• 2023

Performance analysis for work-learning dual system has been mainly conducted from the perspective of diagnosing the effectiveness of policies at the macro level. This study aims to analyze issues in organizational management of the work-learning dual system training center by conducting an analysis focusing on the organizational performance of the work-learning dual system training center's employees. As a result of the analysis, it was confirmed that the perception and attitude of employees toward the work-learning dual training center differed depending on the type of work-learning dual system and the type of employment contract. Among the types of work-learning dual system, overall, in the case of IPP, the organizational performance of employees was low, while the apprenticeship was relatively high. As for the type of employment contract, the need for institutional improvement has been derived, especially for the project contract workers.

• Korean Journal of Medicinal Crop Science
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• v.15 no.4
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• pp.233-240
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• 2007

Extractions of Artemisia princeps Pampanini were obtained by using water and ethanol at different temperatures ($60^{\circ}C,\;100^{\circ}C$) with or without ultrasonification process (40 kHz). Yield of ultrasonificated extracts were about 20% higher than that of control group. Cytotoxicity of all conditions through adding 1.0 mg/$m{\ell}$ was below 37%, and treated with ultrasonification group was lower than the other group, about $5{\sim}8%$. $100^{\circ}C$ water extract with ultrasonification was higher anticancer activities as maximum 73% and higher selectivities at concentrations over 0.8 mg/$m{\ell}$. The extracts treated with ultrasonification were higher anticancer activities than the control. Densitometric analysis of bcl-2 revealed that extracts of high anticancer activity had low density. This results suggest that expression of bcl-2 protein by adding of Artemisia princeps Pampanini extracts relative to taking cancer. To conclude, optimum condition for efficient extraction of Artemisia princeps Pampanini is using water with ultrasonification at over $60^{\circ}C$ below $100^{\circ}C$.

• Radiation Oncology Journal
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• v.13 no.2
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• pp.191-198
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• 1995

Purpose: This analysis was to compare the result of radiation alone and chemoradiation in cervical cancer in terms of response, survival, failure, and complication. Materials and Methods: A retrospective analysis of 135 cervical cancer patients treated with definitive radiotherapy from November 1985 to December 1991 was performed. Fifty-six patients were treated with radiation alone and 79 patients were treated with cisplatin-based chemotherapy plus radiation. Follow-up period ranged from 5 to 105 months with a median 47 months. According to the FIGO classification, the patients were subdivided into 18 $(13.3\%)$ stage IB, 7 $(5.2\%)$ stage IIA, 97 $(71.9\%)$ stage IIB, and 9 $(6.7\%)$ stage IIIB. Results: A complete response was noted in 51 patients $(91.1\%)$ of the radiation alone group, and 68 patients $(86.1\%)$ of the chemoradiation group. There was no statistical difference in complete response rate between the two groups. Overall survival rate at 5 years was $73.3\%$. According to stage, overall survival rates at 5 years were $88.9\%$ in stage IB, $85.7\%$ in stage IIA, $73.8\%$ in stage IIB, and $37.5\%$ in stage IIIB, respectively. According to treatment modality, overall survival rates at 5 years were $81.9\%$ in the radiation alone group, $67.0\%$ in the chemoradiation group (p=0.22). Disease-free survival rate at 5 years were $70.4\%$ in the radiation alone group. $68.5\%$ in the chemoradiation group (p=0.85) Locoregional control rates at 5 years were $76.1\%$ in the radiation alone group, $73.8\%$ In the chemoradiation group (p=0.70). Distant disease-free survival rates at 5 years were $83.9\%$ in the radiation alone group, $90.3\%$ in the chemoradiation group (p=0.59). Treatment-related bone marrow suppressions were noted in 3 $(5.4\%)$ patients of the radiation alone group, 14 patients $(17.7\%)$ of the chemoradiation group (p(0.05). Grade 2 vesical complications were noted in 14 patients of the radiation alone group. and 10 Patients of the chemoradiation group. Grade 2 rectal complications were noted in 2 patients of the radiation alone group, and 3 Patients of the chemoradiation group. One case of rectal perforation was noted in the chemoradiation group, and grade 2 small bowel obstructions were noted in 2 patients of the radiation alone group. There were no statistical differences in the incidence of vesicar, rectal, and small bowel complicaions between the two groups. Conclusion: No statistical difference was found between the radiation alone group and the chemoradiation group in terms of response, survival, and failure. but the incidence of bone marrow suppression was higher in the chemoradiation group.

• Journal of Practical Engineering Education
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• v.11 no.1
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• pp.61-73
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• 2019

Recently the Korean life-long occupational skill development system is undergoing rapid change and innovation on the basis of NCS (National Competency Standards). In order for the NCS-based occupational training system to be successfully established, it is required to be accepted and applied in the higher education. Universities, however, hesitate to adopt NCS-based contracted education programs of the work-and-study cooperative system due to low relevance of university education to industrial needs and absence of the reference operation model for the NCS-based contracted education programs considering Korean small companies' particular needs. This study aims to develop and apply a reference operation model for NCS-based contracted education programs of the university-linked work-and-study parallel system, focusing on the Department of Mechanical Design Engineering of College of Work and Study in Parallel, Koreatech. In addition, several operational guidelines are suggested within the framework of current law and regulations for successful diffusion of the NCS-based reference operation model. The results of this study are expected to contribute to nation-wide proliferation of NCS-based contracted education programs in the higher education and motivating companies and universities to participate in the work-and-study parallel initiatives.

• The Transactions of the Korea Information Processing Society
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• v.3 no.7
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• pp.1687-1696
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• 1996

Most of the main memory database systems use two-phase locking(2PL)for concurrency control. The 2PL method is preferred over other methods for concurrency control because of its simplicity and common usage. However, conventional concurrency control solution will function poorly when the data are memory resident. In this paper, we propose a new optimistic concurrency control protocol for a main memory database system. In our proposed protocol, transaction conflict information is used in validation phase to improve data conflict resolution decisions. Our experiments show that the proposed protocol performs better than 2PL in terms of throughput for main memory database system enshrinements.

• Proceedings of the Korean Information Science Society Conference
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• 2010.06c
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• pp.534-539
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• 2010

OpenMP 프로그램의 수행 중에 발생하는 자료 경합과 같은 병행성 오류는 디버깅을 위하여 반드시 탐지되어야만 한다. 그러나 이를 탐지하는 것은 어려운 일이다. 접근사건의 발생 후 관계를 기반으로하는 경합 탐지 기법은 프로그램의 수행 중에 발생하는 스레드의 병행성 정보를 식별하기위한 레이블을 생성하고, 생성된 스레드의 레이블을 기반으로 공유변수에 접근하는 사건을 접근역사를 통해 감시함으로써 경합을 탐지한다. 이러한 경합 탐지의 방법에서 레이블 생성을 위한 NR 레이블링 기법은 병행성 정보생성 시에 지역자료 구조를 사용함으로써 병목현상이 발생하지 않으며, 접근역사에 저장하는 레이블의 크기가 상수 값을 갖는 공간적 효율성을 제공한다. 또한 부모스레드의 정보역사를 정렬된 리스트 형태로 가져 병행성 정보 비교 시에 이진탐색이 가능하므로 시간적 효율성을 가지는 우수한 기법이다. 그러나, NR 레이블링은 레이블의 생성시에 부모스레드의 정보역사를 유지하기 위해서 내포 병렬성의 깊이에 의존하는 시간적 비용이 요구된다. 본 논문에서는 부모스레드의 정보역사 유지를 위해 상수적인 시간 및 공간적 복잡도를 갖도록 NR 레이블링 기법을 개선한다. 합성 프로그램을 이용하여 실험한 결과에서 개선된 기법은 최대 병렬성의 증가에 따라 레이블의 생성과 유지시 기존의 기법보다 평균 4.5배 빠르고, 레이블링을 위해 평균 3배 감소된 기억공간을 요구하며, 내포 병렬성에 의존적이지 않음을 보인다.

• Journal of KIISE:Software and Applications
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• v.29 no.5
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• pp.336-344
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• 2002

In concurrent object-oriented languages, inheritance and concurrence are the primary features. But concurrent objects and inheritance have conflicting characteristics thereby simultaneously use of them causes the problem, so called inheritance anomaly, which requires code redefinition of inherited methods to maintain integrity of objects. In this paper, to solve this inheritance anomaly without broken of encapsulation, we introduce the state abstraction concept and map internal states of the encapsulated object into abstract slates. And also, we design the inheritance interface for efficient inheritance. Through the inheritance interface containing abstract state set, though redefinition of the method is incurred, we can remove the influence of other classes in inheritance hierarchy. And also, we can solve the inheritance anomaly problems.