• The Journal of Society for e-Business Studies
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• v.24 no.1
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• pp.105-120
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• 2019

The World Health Organization (WHO) and other government agencies aroundthe world have warned against antibiotic-resistant bacteria due to abuse of antibiotics and are strengthening their care and monitoring to prevent infection. However, it is highly necessary to develop an expeditious and accurate prediction and estimating method for preemptive measures. Because it takes several days to cultivate the infecting bacteria to identify the infection, quarantine and contact are not effective to prevent spread of infection. In this study, the disease diagnosis and antibiotic prescriptions included in Electronic Health Records were embedded through neural embedding model and matrix factorization, and deep learning based classification predictive model was proposed. The f1-score of the deep learning model increased from 0.525 to 0.617when embedding information on disease and antibiotics, which are the main causes of antibiotic resistance, added to the patient's basic information and hospital use information. And deep learning model outperformed the traditional machine hospital use information. And deep learning model outperformed the traditional machine learning models.As a result of analyzing the characteristics of antibiotic resistant patients, resistant patients were more likely to use antibiotics in J01 than nonresistant patients who were diagnosed with the same diseases and were prescribed 6.3 times more than DDD.

• Journal of Digital Convergence
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• v.18 no.12
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• pp.425-434
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• 2020

Background: Viral infection outbreaks are emerging public health concerns. They often exhibit seasonal patterns that could be predicted by the application of big data and bioinformatic analyses. Purpose: The purpose of this study was to identify trends in diarrhea-causing viruses such as rotavirus (Gr.A), norovirus G-I, and norovirus G-II in Cheonan, Korea. The identified related factors of diarrhea-causing viruses may be used to predict their trend and prevent their infections. Method: A retrospective analysis of 4,009 fecal samples from June 2010 to December 2019 was carried out at Dankook University Hospital in Cheonan. Reverse transcription-PCR (RT-PCR) was employed to identify virus strains. Information about seasonal patterns of infection was extracted and compared with local weather data. Results: Out of the 4,009 fecal samples tested using multiplex RT-PCR (mRT-PCR), 985 were positive for infection with Gr.A, G-I, and G-II. Out of these 985 cases, 95.3% (n = 939) were under 10 years of age. Gr.A, G-I, and G-II showed high infection rates in patients under 10 years of age. Student's t-test showed a significant correlation between the detection rate of Gr.A and the relative humidity. The detection rate of G-II significantly correlated with wind-chill temperature. Conclusion: Climate factors differentially modulate rotavirus and norovirus infection patterns. These observations provide novel insights into the seasonal impact on the pathogenesis of Gr.A, G-I, and G-II.

• Pediatric Infection and Vaccine
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• v.29 no.3
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• pp.125-130
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• 2022

For the extended duration of the coronavirus disease 2019 (COVID-19) pandemic, reports emerged that mother-to-child transmission rates were low. However, the pandemic protocols including strict isolation, testing for severe acute respiratory syndrome coronavirus 2, and negative pressure isolation remained in Korea. Recently, the guideline for the management of neonates born to mothers with COVID-19 have been revised based on guidelines in other countries. Here, we introduce this newly developed guideline and review the foreign guidelines that were used for reference.

• The Korean Society of Law and Medicine
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• v.23 no.4
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• pp.29-74
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• 2022

As social disasters occur under the Disaster Management Act, which can damage the people's "life, body, and property" due to the rapid spread and spread of unexpected COVID-19 infectious diseases in 2020, information collected through inspection and reporting of infectious disease pathogens (Article 11), epidemiological investigation (Article 18), epidemiological investigation for vaccination (Article 29), artificial technology, and prevention policy Decision), (3) It was used as an important basis for decision-making in the context of an infectious disease crisis, such as promoting vaccination and understanding the current status of damage. In addition, medical policy decisions using infectious disease data contribute to quarantine policy decisions, information provision, drug development, and research technology development, and interest in the legal scope and limitations of using infectious disease data has increased worldwide. The use of infectious disease data can be classified for the purpose of spreading and blocking infectious diseases, prevention, management, and treatment of infectious diseases, and the use of information will be more widely made in the context of an infectious disease crisis. In particular, as the serious stage of the Disaster Management Act continues, the processing of personal identification information and sensitive information becomes an important issue. Information on "medical records, vaccination drugs, vaccination, underlying diseases, health rankings, long-term care recognition grades, pregnancy, etc." needs to be interpreted. In the case of "prevention, management, and treatment of infectious diseases", it is difficult to clearly define the concept of medical practicesThe types of actions are judged based on "legislative purposes, academic principles, expertise, and social norms," but the balance of legal interests should be based on the need for data use in quarantine policies and urgent judgment in public health crises. Specifically, the speed and degree of transmission of infectious diseases in a crisis, whether the purpose can be achieved without processing sensitive information, whether it unfairly violates the interests of third parties or information subjects, and the effectiveness of introducing quarantine policies through processing sensitive information can be used as major evaluation factors. On the other hand, the collection, provision, and use of infectious disease data for research purposes will be used through pseudonym processing under the Personal Information Protection Act, consent under the Bioethics Act and deliberation by the Institutional Bioethics Committee, and data provision deliberation committee. Therefore, the use of research purposes is recognized as long as procedural validity is secured as it is reviewed by the pseudonym processing and data review committee, the consent of the information subject, and the institutional bioethics review committee. However, the burden on research managers should be reduced by clarifying the pseudonymization or anonymization procedures, the introduction or consent procedures of the comprehensive consent system and the opt-out system should be clearly prepared, and the procedure for re-identifying or securing security that may arise from technological development should be clearly defined.

• Parasites, Hosts and Diseases
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• v.28 no.1
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• pp.45-52
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• 1990

Intestinal histopathological changes due to infection with Echinostcma hortense (Trematoda) were studied in rats after experimental infection with the metacercariae. The metacercariae were obtained from the tadpoles of Rana nigrcmaculata, a second intermediate host infected in the laboratory. Total 18 albino rats(Sprague-Dawley) were given 200 matacercariae each and sacrificed on the day 1, 3, 7, 11, 22 or 44 post-infection(PI) Segments of- the small intestine at 1, 3, 5, 8 and 30 cm posterior to the pylorus(PTP) were rejected and studied histopathologically. 1. The flukes were seen to have intruded into the intervillous space in the upper small intestine at early stages(1∼3 days PI), however, they were located mainly in the intestinal lumen at later stages(7∼44 days PI) . The flukes were sucking and destroying the epithelial layers of villi with their oral and ventral suckers. 2. Histopathological changes of the intestine were recognizable in as early as 1∼3 days after infection, and the changes became severer as the infection progressed. 3. The intestinal mucosa was histopathologically characterized by villous atrophy and crypt hyperplasia throughout the infection period. Major villous changes were blunting, fusion, severe destruction and loss of epithelial layers of villi. Villous/crypt(V/C) height ratio was remarkably reduced from 3 : 1 in controls to 1 : 1 in severely infected animals. In the stroma of villi, inaamma- tory cell infiltrations, vascular congestion, edema, and/or fibrosis were recognized. The goblet cells were increased in number after 11 days PI. It was revealed in the present study that the pathological changes in the intestine of rats infected with E. hortense were chieay confined to the mucosal layer of the upper small intestine, however, the changes were very severe accompanying remarkable destruction of villi and loss of mucosal integrity, and persistent until 44 days PI.

• Journal of the Korea Convergence Society
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• v.8 no.1
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• pp.51-59
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• 2017

It is to establish preliminary data about healthcare convergencr of infection control by performing a bacterial contamination test for CT scanner as well as general radiographic systems in the emergency rooms of general hospitals. The period was December 1 ~ December 31, 2015. It is detect in the emergency rooms of 7 medical facilities including 2 in Seoul, and 1 in Gyeonggi-do Province, and 2 in Jeonla-do Province, and 2 in Chungcheong-do Province. The surface contamination strains detected from CT scanner in the radiology department emergency rooms were Micrococcus species(4,5%), Stenotrophomonas maltophilia(9%), Enterococcus faecium(4.5%), Providencia stuartii(4.5), and Gram negative bacilli(4.5%). Also, the surface contamination strains detected from general radiographic system in the radiology department emergency rooms were Providencia stuartii(11%), Klebsiella pneumonia(3.5%), Stenotrophomonas maltophilia(11%), Pantoea species(11%), Acinetobacter baumannii(3.5%), Micrococcus species(3.5%), Escherichia coli(3.5%), Enterobacter species(3.5%), and Gram negative bacilli(11%). Considering that the regions of most detection were all the places closely related to patients, radiologists would have to thoroughly clean with alcohol before and after a test.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.11
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• pp.5094-5101
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• 2011

In order to investigate recurrence rate and risk factors for recurrence of gastric cancer after curative resection, we examined blood biochemical profile and clinicopathological features of 386 gastric cancer patients by using medical charts and data of hospital cancer registry from September 2010 to May 2011. Chi-square test and logistic regression analyses were performed to identify risk factors. The recurrence rate of all gastric cancer patients was 2.6%; The recurrence rate by gender was 3.45% in male and 0.89% in female, and that was 4 times higher in male than in female. On univariate logistic regression analyses, lymph node metastases(OR=8.793), Helicobactor pylori infecton(OR=6.495), abnormal total cholesterol(OR=14.333) were related to recurrence. On multivariate logistic regression analyses, lymph node metastases and H. pylori infection were very important risk factors for recurrence of gastric cancer. In conclusion, lymph node metastases, H. pylori infection, and total cholesterol control were very important to prevent recurrence of gastric cancer, and it needs to monitor blood biochemical (C-reactive protein, carcinoembryonic antigen, etc) for the early detection of gastric cancer recurrence.

• Journal of Internet of Things and Convergence
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• v.8 no.6
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• pp.35-47
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• 2022

This study aims to identify the degree of job stress related to COVID-19, emotional labor, empowerment, and retention intention of nurses in hospitals dedicated to infectious diseases, and confirmed the effect of job stress related to COVID-19, emotional labor, and empowerment on retention intention. The data collection of this study was conducted from August 27, 2021 to September 17, 2021 through a structured questionnaire targeting 162 nurses at an infectious disease hospital in S city. The data were analyzed analyzed using frequency and percentage, mean and standard deviation, t-test, ANOVA, Pearson's Correlation Coefficient, and multiple linear regression using SPSS/WIN 25.0. As a result of analyzing differences according to general characteristics, retention intention showed a significant difference according to work department and work satisfaction. And as a result of analyzing the correlation between retention intention and COVID-19 related job stress, emotional labor, and empowerment, it showed a significant negative correlation (r=-0.215, p=0.006) with job stress related to COVID-19 and a significant positive correlation (r=0.343, p<0.001) with empowerment. As a result of multiple linear regression analysis, job satisfaction, job stress related to COVID-19, and empowerment were identified as significant variables affecting retention intention (F=23.751, p<0.001), and the explanatory power was 30.0%. Through the above results, we intend to provide basic data for strategic development for efficient nursing manpower management.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.15 no.2
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• pp.153-160
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• 2008

Purpose: This study was done to examine the level of compliance and the relation of related factors of nosocomial infection control among nurses in emergency rooms. The data will provide fundamental information for developing programs for nosocomial infection control in the emergency room. Method: Study participants were 183 nurses working in emergency rooms in general hospitals that had more than 500 beds and were located in Daegu, Daejeun, and Pusan. The survey was carried out from March 7 to March 26, 2006 and a structured questionnaire was used. Descriptive statistics, t-test, ANOVA and Sheffe test with SPSS 14.0 were used to analyze the data. Results: The average level for practice of infection control was relatively low Levels of compliance were high when the participants had: 1) regular conferences for nosocomial infection control, 2) positive perception of protection devices, 3) knowledge of whom to report and experiences of reporting needle stick injuries, 4) hospital guidelines for infection control and 5) enough equipment supplies from the hospital. Conclusion: Nosocomial infection control among emergency room nurses could be improved via personal, psychosocial, and organizational factors and related education.

• Korean Journal of Adult Nursing
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• v.24 no.2
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• pp.119-129
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• 2012

Purpose: The purpose of this study was to test hand hygiene behavior model of hospital nurses, based on theory of planned behavior. Methods: Data were collected from 253 nurses from four university hospitals for the period of December 2010 to January 2011. Data were analyzed using of SAS (ver.9.1). Fitness of the study model was identified with SAS PROC CALIS. Results: The overall fitness was $x^2$=57.81 (df=13, $p$ <.001), GFI=.99, AGFI=.99, CFI=.95, NFI=.93. The variance of actual implementation of hand hygiene by predictor variables was 11.0% and the variance of intention to hand hygiene was 53.5%. Variable that had a direct effect on hand hygiene behavior was intention. Perceived behavior control and attitude affected hand hygiene behavior indirectly. Control belief had a direct effect on perceived behavior control and had an indirect effect on intention and behavior. Behavioral belief had a direct effect on attitude and an indirect effect on intention and behavior. Conclusion: The study provides basic information for understanding nurses' hand hygiene behavior. Further testing of the model will indicate which variables can contribute to improved hand hygiene.