• Journal of the Korea institute for structural maintenance and inspection
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• v.21 no.1
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• pp.1-8
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• 2017

Three small scale hollow circular reinforced concrete columns with aspect ratio 4.5 were tested under cyclic lateral load with constant axial load. Diameter of section is 400 mm, hollow diameter is 200 mm. The selected test variable is transverse steel ratio. Volumetric ratios of spirals of all the columns are 0.302~0.604% in the plastic hinge region. It corresponds to 45.9~91.8% of the minimum requirement of confining steel by Korean Bridge Design Specifications, which represent existing columns not designed by the current seismic design specifications or designed by seismic concept. The longitudinal steel ratio is 2.017%. The axial load ratio is 7%. This paper describes mainly crack behavior, load-displacement hysteresis loop, seismic performance such as equivalent damping ratio, residual displacement and effective stiffness and flexural over-strength of circular reinforced concrete bridge columns with respect to test variable. The regulation of flexural over-strength is adopted by Korea Bridge Design Specifications (Limited state design, 2012). The test results are compared with nominal strength, result of nonlinear moment-curvature analysis and the design specifications such as AASHTO LRFD and Korea Bridge Design Specifications(Limited state design).

• Journal of the Korean Wood Science and Technology
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• v.29 no.4
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• pp.1-8
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• 2001

This study was carried out to investigate the strength and stiffness of drift pinned and bolted joints with steel-plates by the tension-type lateral strength tests. Specimens were solid wood of Pinus densiflora. Bolt and drift pin were jointed with inserted steel plates. Tests were conducted with combinations of two loading directions (parallel to the grain : 0 degree, perpendicular to the grain : 90 degree) and three diameters of fasteners (d = 6 mm, 10 mm, 12 mm). The results obtained were as follow: 1. In the test of the parallel to the grain, maximum loads were increased with increasing of the diameter of bolt and drift pin in the same end distance. In the test of perpendicular to the grain with diameter 10 mm and 12 mm, specimens mostly were failed with horizontal splits in woods reaching the yield load of drift pinned and bolted joints. 2. The ratio of maximum load to the yield load determined by the so-called "5% offset method", was great in bolted joints in the parallel to the grain This trend become more remarkable as the slenderness ratio was increased. 3. The calculated yield strength was agreed well with the experimental results of drift pinned joint(0 degree).

• Journal of Life Science
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• v.25 no.6
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• pp.724-731
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• 2015

Mesenchymal stem cells (MSCs) are characterized by their multipotency capacity, which allows them to differentiate into diverse cell types (bone, cartilage, fat, tendon, and neuron-like cells) and secrete a variety of trophic factors (ANG, FGF-2, HGF, IGF-1, PIGF, SDF-1α, TGF-β, and VEGF). MSCs can be easily isolated from human bone-marrow, fat, and umbilical-cord tissues. These features indicate that MSCs might be of use in stem-cell therapy. However, MSCs undergo cellular senescence during long-term expansion, and this is accompanied by functional declines in stem-cell potency. In the human body, because of their senescence and declines in their microenvironmental niches stem cells fail to maintain tissue homeostasis, and as a result, senescent cells accumulate in tissues. This can lead to age-related diseases, including degenerative disorders and cancers. Recent studies suggest that the number of histone modifications to stem cells’ genomes and aberrant alterations to their DNA methylation increase as stem cells progress into senescence. These epigenetic alterations have been partly reversed with treatments in which DNA methyltransferase (DNMT) inhibitors or histone deacetylase (HDAC) inhibitors are introduced into replicative senescent-MSCs. This review focuses on epigenetic alteration in replicative senescent-MSCs and explains how epigenetic modifications are widely associated with stem-cell senescences such as differentiation, proliferation, migration, calcium signaling, and apoptosis.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.35 no.4
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• pp.342-347
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• 2002

Ciliates have the possibility of a new live food in marine finfish culture because of their wide range of body size, thin tell wall, show motility, and fast reproduction rate. In this research, six species of ciliates were isolated from south coast and salt pond in Korea. The fitness of these species as a live food was evaluated in terms of size, motility, suspensibility and cell density. As the result, Euplotes sp. (K-1) was found suitable to be a new live food which might substitute rotifers, Brachionus plintilis and B. rotundiformis in fish larvae culture. The modified $F{\emptyset}yn's$ Erdschreiberd media, MErds-2 with the addition of glycine, glucose and yeast extract increased six times higher growth rate of Euplotes sp. (K-1) than the basic F$\emptyset$yn's Erdschreiberd media. The optimum water temperature, pH and light intensity for this ciliates were $22.5^{\circ}C$, 8 and 2,000 lux, respectively, and its culture environmental range was relatively wide, On the other hand, this ciliate fed baker's yeast, Saccharomyces cererisiae grew up to 1,240 inds./mL with the inocula of 100 inds./mL within 7 days. The results of the study showed that Euplotes sp. (K-1) has a potential to be utilized as a new live food in fish larvae culture.

• Restorative Dentistry and Endodontics
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• v.31 no.1
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• pp.1-10
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• 2006

The purpose of this study was to compare the shaping ability of three Ni-Ti file systems used by dental students or the experts and consequently to aid in choosing a proper systems for educational courses of dental students and beginners. Fifty students and ten dentists who have clinical experience over two years prepared 180 simulated root canals in resin blocks with three Ni-Ti systems; $ProFile^{(R)}\;(PF),\;HeroShaper^{(R)}\;(HS),\;K3^{TM}\;(K3)$. After preparation, the Ni-Ti files were evaluated for distortion and canal preparation time was recorded. The images of pre- and post-instrumented canals were scanned and superimposed. Amounts of increased canal widths, deviation, and centering ratio were calculated at apical 1, 3 and 5 mm levels and statistical analysis was performed The results were as follows : 1. HS showed the shortest preparation time and instrumented canal width in K3 was significantly larger than other groups (P<0.05). 2. At 1 and 3mm levels, all groups had outward deviation. In student group, at the 1mm level, PF had the least deviation (P<0.05). 3. In the centering ratio, the PF had the best centering ability compared to the others at 5mm level. At 1 and 3mm levels, HS and PF had better abilities than K3. Student group had better ratio than the expert at 3mm level with PF (P<0.05). Based on the results, it is surmised that the $ProFile^{(R)}$ is the safest and most ideal instrument for students and beginners.

• Journal of the Earthquake Engineering Society of Korea
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• v.10 no.1 s.47
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• pp.41-49
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• 2006

Through the 1982 Urahawa-ohi and the 1995 Kobe earthquakes, a number of bridge columns were observed to develop a flexural-shear failure due to the bond slip as a consequence of premature termination of the column longitudinal reinforcement. Because the seismic behavior of RC bridge piers is largely dependent on the performance of the plastic hinge legion of RC bridge piers, it is desirable that the seismic capacity of RC bridge pier is to evaluate as a curvature ductility. The provision for the lap splice of longitudinal steel was not specified in KHBDS(Korea Highway Bridge Design Specification) before the implementation of 1992 seismic design code, but the lap splice of not more than 50%, longitudinal reinforcement was newly allowed in the 2005 version of the KHBDS. The objective of this research is to investigate the distribution and ductility of the curvature of RC bridge column with the lap splice of longitudinal reinforcement in the plastic hinge legion. Six (6) specimens were made in 600 mm diameter with an aspect ratio of 2.5 or 3.5. These piers were cyclically subjected to the quasi-static loads with the uniform axial load of $P=0.1f_{ck}A_g$. According to the slip failure of longitudinal steels of the lap spliced specimen by cyclic loads, the curvatures of the lower and upper parts of the lap spliced region were bigger and smaller than the corresponding paris of the specimen without a lap splice, respectively. Therefore, the damage of the lap spliced test column was concentrated almost on the lower part of the lap spliced region, that appeared io be failed in flexure.

• Journal of the Earthquake Engineering Society of Korea
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• v.7 no.2
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• pp.9-20
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• 2003

At present, the information on the foundation-structure interaction is lacking. As a result, the seismic performance evaluation of buildings seldom considers the effect of the foundation performance on the building responses. Recent earthquakes such as the 1993 Hokkaido Nansei-oki Earthquake(M=7.8), the 1994 Northridge Earthquake(M=6.7), the 1995 Hyogoken-Nambu Earthquake(M=7.2), and the 1999 Chi-Chi Earthquake (M=7.6) have shown that building damages are significantly affected by the degree of damage sustained by the building foundation and the interaction between the building and the foundation. This paper presents a nonlinear seismic analysis method for the seismic performance evaluation of reinforced concrete buildings which considers the pile foundation-structure interaction. The proposed method is applied to an actual building which was damaged during the 1993 Hokkaido Nansei-oki Earthquake. The result reveal that the method is able to predict the performance of the building.

• Journal of the Earthquake Engineering Society of Korea
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• v.7 no.2
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• pp.75-84
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• 2003

Most structures are expected to deform beyond the limit of linearly elastic behavior when subjected to strong ground motion. Seismic evaluation of structure requires an estimation of the structural performance in terms of displacement demand imposed by earthquakes on the structure. The nonlinear response history analysis(NRHA) among various nonlinear analysis methods is the most accurate to compute seismic performance of structures, but it is time-consuming and necessitate more efforts. The nonlinear approximate methods, which is more practical and reliable tools for predicting seismic behavior of structures, are extensively studied. Among them, the capacity spectrum method(CSM) is conceptually simple, but the iterative procedure is time-consuming and may sometimes lead to no solution or multiple solutions. This paper considers a nonlinear direct spectrum method(NDSM) to evaluate seismic performance of mixed building structures without iterative computations, given dynamic property T from stiffness skeleton curve and nonlinear pseudo acceleration $A_{y}$/g and/or ductility ratio $\mu$ from response spectrum. The nonlinear response history analysis has been performed and analyzed with various earthquakes for estimation of reliability and practicality of NDSM with mixed building structures.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.37 no.12
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• pp.91-97
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• 2000

With the brilliant development of information communication and the rapid spread of internet, current network communication is carrying several up-to-date functions such as electronic commerce, activation of electro currency or electronic signature and will produce more advanced services in the future. Information communication network such as that electronic commerce would demand the more safe and transparent guard of network, and anticipate the more fast performance of network. In this paper, in order to meet the several demands, DES(data encryption standard) with parallel feistel structure, which feistel structure of the basic structure of DES is transformed into in parallel, is proposed. The existing feistel structure can't use pipeline method for the structural problem of DES itself-the propagation of error. therefore, this modified parallel feistel structure could improve largely the performance of DES which had to have the trade-off relation between data processing speed and data security and in addition a method proposed in SEED having adopted the modified parallel feistel structure shows more excellent secure function and/or fast processing ability. The used CAD Tool use Synopsys Ver. 1999. 10 in both of synthesis and simulation.

• Journal of the Korea Concrete Institute
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• v.23 no.3
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• pp.321-330
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• 2011

Recently, the effects of high temperature and fiber content on the residual mechnical properties of high-strength concrete were experimentally investigated. In this paper, residual mechanical properties of concrete with water to cement (w/c) ratios of 0.55, 0.42 and 0.35 exposed to high temperature are compared with those obtained in fiber reinforced concrete with similar characteristics ranging from 0.05% to 0.20% polypropylene (PP) fiber volume percentage. Also, factors including pre-load levels of 20% and 40% of the maximum load at room temperature are considered. Outbreak time, thermal strain, length change, and mass loss were tested to determine compressive strength, modulus of elasticity, and energy absorption capacity. From the results, in order to prevent the explosive spalling of 50 MPa grade concretes exposed to high temperature, more than 0.05 vol. % of PP fibers is needed. Also, the cross-sectional area of PP fiber can influence the residual mechanical properties and spalling tendency of fiber reinforced concrete exposed to high temperature. Especially, the external loading increases not only the residual mechanical properties of concrete but also the risk of spalling and brittle failure tendency.