• Korean Journal of Clinical Laboratory Science
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• v.53 no.2
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• pp.143-150
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• 2021

The recent spread of novel and highly variant pathogenic viruses, including the coronavirus (SARS-CoV-2), has increased the demand for diagnostic testing for rapid confirmation. This has resulted in investigating the functional capability of each space, and preparing facility guidelines to secure the safety of medical technologists. During viral evaluations, there is a requirement of negative pressure facilities along with thread separation, during pre-treatment of samples and before nucleic acid amplification. Space composition therefore needs to be planned by considering unidirectional air flow. This classification of safety management facilities is designated as biosafety level 2, and personal protective equipment is placed accordingly. In case of handling dangerous materials, they need to be carried out of the biosafety cabinet, and sterilizers are required for suitable disposal of infectious agents. A common feature of domestic laboratories is maintenance of the sample pre-treatment space at a negative pressure of -2.5 Pa or less, and arranging separate pre-treatment and reagent preparation spaces during the test process. We believe that the data generated in this study is meaningful, and offers an efficient direction and detailed flow for separation of the inspection process and space functions. Moreover, this study introduces construction of the laboratory by applying the safety management standards.

• Journal of Environmental Impact Assessment
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• v.31 no.6
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• pp.409-422
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• 2022

Riverine wetlands are an important element of the river ecosystem and account for approximately 38% of the inland wetlands surveyed so far. The Shincheon Wetland located in Mangyeong River is also a channel wetland as the flow rate is slowed by the constructed weirs, leading to sediment accumulation. To identify the conservation value and ecological characteristics of Shincheon Wetland, its vegetation and plant diversity were identified using a phytosociological method, and a total of 45 vegetation-related datasets were collected. Overall, 24 plant communities, comprising a total of 153 taxa (49 families, 117 genera, 146 species, 2 subspecies, 5 varieties) were identified. The plant with the highest appearance rate in the communities was Humulus japonicus Siebold & Zucc. In addition, annual herb species, including Rumex crispus L., Bromusjaponicus Thunb., Erigeron annuus (L.) Pers., and Artemisia indica Willd. were frequently observed to be growing in the secondary grassland. Naturalized plants were surveyed in the 38 taxa; the urbanization index was 10.3% and the naturalized index was 24.8%. Plant communities were largely classified into submerged vegetation, floating and floating-leaved vegetation, annual and biennial vegetation, perennial herb vegetation, and woody vegetation. The distribution of plant communities reflecting various habitats, including the lentic and lotic zone maintaining a constant water depth, littoral zone experiencing intermittent water level fluctuations, and dry floodplain environment was also confirmed. Overall, plant community development plays an important role in the habitat for wild animals; therefore, it is expected to positively impact biodiversity enhancement.

• Korean Journal of Mineralogy and Petrology
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• v.35 no.4
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• pp.431-445
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• 2022

A quantitative phase analysis method of X-ray powder diffraction was studied to determine the mineral content of clay-rich rocks practically as well as effectively. For quantitative X-ray powder diffraction analysis of the clay-rich rocks, it is necessary to prepare whole-rock powder samples with a random orientation by side mounting method. In addition, for the identification of the clay minerals in the rock, it is required to prepare an oriented mount specimen with a clay particle size of 2 ㎛ or less, ethylene glycol treatment, and heat treatment. RIR (reference intensity ratio) and Rietveld method were used for the quantitative analysis of the clay-rich rocks. It was possible to obtain the total clay and the non-clay minerals contents from the whole-rock X-ray diffraction profiles using the RIR values. In addition, it was possible to calculate the relative content of each clay mineral from the oriented X-ray diffraction profiles of the clay particle size and assign it to the total clay. In the Rietveld method of whole-rock X-ray diffraction, effective quantitative values were obtained from the Rietveld diffraction patterns excluded the region of less than 10 degrees (2θ). Similar quantitative values were shown in not only the RIR but the Rietveld methods. Therefore, the analysis results indicate a possibility of a routine quantitative analysis of clay-rich rocks in the laboratory. However, quantitative analysis of clay minerals is still a challenge because there are numerous varieties of clay minerals with different chemical and structural characteristics.

• Korean Journal of Environment and Ecology
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• v.36 no.1
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• pp.30-55
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• 2022

This study conducted a flora survey in the areas of Mt. Sambong (282m) and Mt. Jaung (263m), located in Paju-si, Gyeonggi-do. A total of 434 taxa, including 6 forms, 34 varieties, 11 subspecies, 383 species, 271 genera, and 94 families, were surveyed in the two mountain areas. The ferns were identified as 24 taxa from 10 families, the gymnosperms as 8 taxa from 2 families, the dicotyledonous plants as 322 taxa from 73 families, and the monocotyledonous plants as 80 taxa from 9 families. Five taxa, including Salix koriyanagi, Cimicifuga heracleifolia, Forsythia koreana, Paulownia coreana, and Hemerocallis hakuunensi, were identified as the Korean endemic plants. Eight taxa, including Cimicifuga heracleifolia, Tylophora floribunda, and Iris minutiaurea as Vulnerable species, andAristolochia contorta, Viola diamantiaca, Lithospermum erythrorhizon, Lilium distichum, andArisaema heterophyllumas Least Concern species, were designated as rare and endangered plants designated by the Korea Forest Service. The invasive alien plants were 40 taxa, including Rumex crispus, Phytolacca americana, Cerastium glomeratum, Silene armeria, Chenopodium album, Chenopodium ficifolium, Magnolia obovata, Potentilla supina, Amorpha fruticosa, Medicago sativa, Robinia pseudoacacia, Trifolium repens, Euphorbia supina, Hibiscus trionum, and Oenothera biennisaccounting for 9.2 percent of the 434 taxa of the surveyed plants. As this area is a mountainous area close to settlement facilities, it is believed that ecological preservation measures and measures of specialized plants should be implemented.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.40 no.2
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• pp.44-58
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• 2022

Bunhwangsa Temple, Baekryulsa Temple and Sambulsa Temple are not famous cultural heritage area, but they are visited by many tourists and are located in Gyeongju National Park and Gyeongju Historic Areas, so environmental and cultural preservations are required. The purpose of this study is to manage the unique environment and landscape of cultural assets by analysing the invasive alien plant of traditional temple of Gyeongju. The whole flora were summarized as 188 taxa including 73 families, 136 genera, 154 species, 3 subspecies, 11 varieties, 4 forms, 5 hybrids and 12 cultivars., and the landscape plants were 163 taxa and 38 taxa of the invasive alien plants. The 13 taxa of invasive alien plants were planted in three temples. The ecosystem disturbance species were 3 taxa including Rumex acetosella, Lactuca seriola and Symphyotrichum pilosum. Invasive alien plants have artificial causes such as landscape planting, but there are also those that are introduced naturally from outside. The parking lot of the temple is expected to be a major propagation path for invasive alien plants due to the large amount of interference and disturbance. Based on the results of this study, the management plans are suggested as follows. First, it is necessary to use native species suitable for the natural environment and traditional landscape of Korea for landscape planting of traditional temples, and development of planting guidelines centered on cultural properties is required. Second, it is necessary to refrain from planting invasive alien plants because traditional temples are located in an important environment and historically. Third, for the preservation of the temple environment, it is necessary to promptly remove the ecosystem disturbance species. Fourth, in order to express the landscape characteristics of traditional temples, a unique planting plan should be established in consideration of the location environment and historicity.

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 2006.05a
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• pp.128-132
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• 2006

관절염이 일어나는 정확한 기전은 아직까지 잘 규명되어 있지 않으나 일반적으로 cytokine, chemokine을 비롯한 여러 가지 조절 물질들 사이의 미묘한 균형이 깨어지는 일이 주된 요인으로 추정되고 있다. 사람의 경우 염증이 일어난 관절 조직에서 활막 세포(synovial fibroblast)는 여러 염증성 사이토카인들을 분비하기도 하며 또 한편 이들 cytokine의 target 세포로 이들의 자극에 대하여 정상인의 그것과 다른 증식 및 활성화 반응을 보이는 등, 다양한 측면에서 관절염증의 유발에 기여하는 것으로 보여진다. 따라서 활막세포 활성화 경로를 DNA Microarray chip을 이용하여 세포 및 분자 수준에서 밝혀 이를 차단할 수 있는 자연물질(natural product)를 선별함으로써 항생제나 스테로이드를 사용하지 않고 돼지의 관절염을 효과적으로 치료 또는 예방할 수 있는 방법을 모색하고자 한다. 6.6kg의 암컷 Yorkshire와 수컷 Landrace의 교배잡으로 왼쪽 뒷다리 슬관절에 십자인대를 파열하여 관절염을 유발하고 8주간 성장을 시킨 후 정상 슬관절과 관절염이 유발된 슬관절의 활막세포로부터 total RNA를 추출한 후 affymetrix Gene chip을 제작하여 Geneplex소프트웨어를 이용하여 데이터를 분석하였다. 분석 결과 unknown 유전자 962개를 포함하여 유전자 발현이 증가된 유전자는 총 1,059개 였으며, unknown 유전자 564개를 포함하여 유전자 발현이 증가된 유전자는 총 639개를 얻었다. 이러한 돼지 관절염에서의 활막세포에 의한 유전적 발현 양상으로부터 molecular function, biological process, pathway등을 이용하여 관절염 지표를 작성할 수 있다.분별을 성공적으로 수행하였다.(p<0.05), 맛, 연도, 다즙성 및 전체적인 기호성은 유의한 차이가 없었다.자체를 악하다고 볼 수 없고 더구나 구원을 이 세상에서의 이탈로 볼 수 없다. 진정한 구원이란 원래 하나님이 보시기에 아름다웠던 그 세상으로의 회복을 포함한다. 이런 면에서 하나님 주권 신앙 하에서 구원이란 전 인격적인 구원, 전 우주적인 구원이 된다. 그렇기 때문에 성도는 세상의 삶과 학문, 예술, 정치, 경제, 사회를 포함한 모든 분야를 하나님의 뜻 가운데서 그 원래의 목적에 부합할 수 있도록 회복시키는 일에 적극 참여해야 한다.자체가 이를 주도하기는 사실 어려움이 있다. 그리고 대형유통점이 영업행위를 영업시간제한에서부터 출점제한에 이르기까지 규제하는 건은 심사숙고하여야 한다. 대형유통점이 국가경제 및 지역사회에 미치는 영향이 부정적인가 긍정적인가에 대해 국내외 학계와 업계에서 여전히 많은 논란이 있기 때문이다. 정부와 지자체에 의한 시장개입은 반드시 필요한 경우에 한해 합당한 방법에 의해 이루어져야 한다. 대형유통점에 대한 규제는 지역사회에 미치는 영향을 다면적으로 평가한 결과에 근거하여 이루어져야 할 것이다. 대부분의 지자체는 체계적인 평가시스템과 객관적인 통계 자료를 갖고 있지 못한 실정이다. 향후 가장 시급한 과제는 시장개방 이후 지난 10년간 대형유통점이 지역사회에 미친 영향에 관한 광범위한 통계자료를 수집하고 이를 체계적으로 분석하여 정책방향을 올바르게 설정하는 것이라 할 수 있다.i와 K. pneumoniae가 존재하며 확산 중임을 시사한다. 앞으로 CTX-M형 ESBL의 만연과 변종 CTX-M형 ESBL의 출연을 감시하기 위한 정기적인 연구와 조사가 필요한 것으로 생각한다., A2-1, B1-1, B2-1의 경우, 강우 일수 감소 이전과

• Korean Journal of Plant Resources
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• v.36 no.2
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• pp.133-171
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• 2023

This study was conducted to prepare basic data by analyzing the biological values and environmental factors of algific talus slope in order to respond to climate change due to the greenhouse effect, and to establish plans for forest biodiversity preserving and managing. Meteorological information was measured and the flora of vascular plants were investigated for six algific talus slope by seasonally from 2020 to 2021. As a result of the investigation, the temperature of all 6 algific talus slope was lower than that of the area where the algific talus slope was located in summer, and flora was 101 families, 350 genera, 621 species, 18 subspecies, 57 variants, 7 varieties, 703 taxa. In sum, it is judged that the algific talus slope has sufficient reasons and value to be preserved because it has excellent micrometeorological value from the cold wind blowing in summer and phytogeographical value in which various plants live in a small area. However, in spite of such an important area, the management of algific talus slope is insufficient, and the algific talus slope is damaged or the ecosystem of the algific talus slope is disturbed. Therefore, it is necessary to establish a systematic conservation and management plan by designating algific talus slope as a forest genetic resource reserve and OECM.

• Korean Journal of Plant Resources
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• v.36 no.1
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• pp.32-61
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• 2023

To investigate the distribution of vascular plants growing at Wetland in Daegu·Gyeongbook, we surveyed from June 2020 to October in 2021. The flora of wetland was classified as a total of 459 taxa comprising of 104 families, 286 genus, 406 species, 12 subspecies, 34 varieties, 6 forma, 1 hybrid. Among them, the rare plants species 5 taxa, endemic plants 11 taxa, floristic regional indicator plants 57 taxa, naturalized plants 27 taxa and wetland plants 74 taxa were recorded. The percentage of urbanization index was 8.44%, the naturalized ratio was 5.88%, respectively.

• Journal of Life Science
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• v.33 no.9
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• pp.746-753
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• 2023

Viral infectious diseases have been regarded as one of the greatest threats to global public health. The recent coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a stark reminder of the threat posed by emerging viral infections. Developing and producing appropriate and efficient vaccines and therapeutics are the only options to combat this pandemic. The COVID-19 pandemic has highlighted the need for novel vaccine platforms to control and prevent emerging viral diseases. Conventional vaccine platforms, including live-attenuated vaccine and inactivated vaccines, pose limitations in the speed of vaccine development, manufacturing capacity, and broad protection for emergency use. Interestingly, vaccination with the SARS-CoV-2 vaccine candidate based on the mRNA-lipid nanoparticle (LNP) platform protected against COVID-19, confirming that the nucleoside-modified candidate is a safe and effective alternative to conventional vaccines. Moreover, the prophylactic strategies against the COVID-19 pandemic have been mRNA nucleic acid-based vaccines and nanoparticle-based platforms, which are effective against SARS-CoV-2 and its variants. Overall, the novel vaccine platform has presented advantages compared with the traditional vaccine platform in the COVID-19 pandemic. This review explores the recent advancements in vaccine technologies and platforms, focusing on mRNA vaccines, digital vaccines, and nanoparticles while considering their advantages and possible drawbacks.

• Journal of Internet Computing and Services
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• v.24 no.4
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• pp.25-36
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• 2023

Today, as AI (Artificial Intelligence) technology is introduced in various fields, including security, the development of technology is accelerating. However, with the development of AI technology, attack techniques that cleverly bypass malicious behavior detection are also developing. In the classification process of AI models, an Adversarial attack has emerged that induces misclassification and a decrease in reliability through fine adjustment of input values. The attacks that will appear in the future are not new attacks created by an attacker but rather a method of avoiding the detection system by slightly modifying existing attacks, such as Adversarial attacks. Developing a robust model that can respond to these malware variants is necessary. In this paper, we propose two methods of generating Adversarial attacks as efficient Adversarial attack generation techniques for improving Robustness in AI models. The proposed technique is the XAI-based attack technique using the XAI technique and the Reference based attack through the model's decision boundary search. After that, a classification model was constructed through a malicious code dataset to compare performance with the PGD attack, one of the existing Adversarial attacks. In terms of generation speed, XAI-based attack, and reference-based attack take 0.35 seconds and 0.47 seconds, respectively, compared to the existing PGD attack, which takes 20 minutes, showing a very high speed, especially in the case of reference-based attack, 97.7%, which is higher than the existing PGD attack's generation rate of 75.5%. Therefore, the proposed technique enables more efficient Adversarial attacks and is expected to contribute to research to build a robust AI model in the future.