• Title/Summary/Keyword: 변이유형

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Noonan Syndrome Confirmed to KRAS Gene Mutation: A Case of KRAS Gene Mutation (KRAS 유전자 변이로 확진된 Noonan 증후군 신생아 1례)

  • Kim, Sung-Woo;Park, So-Eun;Jeong, In-Hyuk;Yoon, Jeong-Won;Lee, Cho-Ae;Jeon, Ji-Hyun
    • Neonatal Medicine
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    • v.18 no.2
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    • pp.374-378
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    • 2011
  • Noonan syndrome is an autosomal dominant disorder characterized by typical facial features, congenital heart disease, and short stature. Diagnosis is difficult only with clinical symptoms and it is recently confirmed with gene study. The genotype-phenotype correlations have been reported. We report a newborn with KRAS gene mutation. This is the second report of case with KRAS gene mutation in Korea. So we hope this case will be a help to diagnosis and treatment of Noonan syndrome from birth.

A Syntactic and Semantic Analysis of Alternations (변이의 통사ㆍ의미론적 고찰)

  • 김현효
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.4 no.3
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    • pp.134-138
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    • 2003
  • The purpose of this study is to analyse the argument alternations in terms of semantic perspective. Argument alternation has long been an interesting topic for the linguists regardless of their linguistic schools. Semantic analysis of argument alternation is attempted by Dowty(2001) based on the Levin(1993)'s classification. The study is focused on the phenomenon where meaning changes with argument alternations even though those sentences look the same syntactically and lineally. 1 tried not only to classify verbs according to the meaning changes but to explain the alternations in semantic point of view. The verbs are divided into 4 types- Touch type, Hit type, Cut type, and Break type. Each type of verbs are tested if they show special characteristics with three alternations-Middle alternation, Body-part possessor Ascension, and Conative Alternation. And semantic analysis is tried based on that classification.

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Distinguishing features and variability of intonation patterns in Korean phonological phrases: The effects of syllable count and segmental content (한국어 음운구 억양 유형의 변별적 특성과 변이 조건에 대한 연구: 음절 수와 분절음 종류의 영향을 중심으로)

  • Oh, Jeahyuk
    • Phonetics and Speech Sciences
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    • v.14 no.3
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    • pp.27-40
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    • 2022
  • This study identifies distinguishing features and variability of intonation patterns in Korean phonological phrases. Syllable count and segmental content, which are phonological conditions, of the intonation of phonological phrases were examined. Based on the four syllables, the intonation of a phonological phrase can be set to LHLH as the basic form, and syllable count acts as a condition for making a variation. The "3 syllables or less condition" changes the intonation from a curved line to a straight line. Variation occurs in pitch bandwidth and fluctuation according to segmental content. The first segment affects the phonological phrase formation bandwidth, and the following segment affects the pitch fluctuation. If the first segment has [+aspirate], [+tense], [+continuant], the intonation is formed in the high band, otherwise, it is formed in the low band. If the second or after segment in the intonation realized in the high band has [-aspirate], [-tense], [-continuant], the pitch is lowered to the lowest level of the low bandwidth. In the intonation realized in the low band, [+aspirate], [+tense], [+continuant] is blocked by the second descent of LHLH.

Structure and Variability of the Isolation Calls of Juvenile Oriental Discoloured Bats (Vespenilio superans) from Korea (안주애기 박쥐 (Vespenilio superans) 새끼의 Isolation Call의 구조와 변화)

  • 서병희;박시룡
    • The Korean Journal of Zoology
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    • v.35 no.2
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    • pp.226-230
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    • 1992
  • 5마리의 안주애기박쥐(Vespenilio superons) 새끼들의 Isolation call에 대해 연구를 하였다. 이들의 소리는 각각의 unit(2-9)로 구성되어 있으며 연결음을 내고 있다. 배음의 unit가운데 기본음의 주파수 범위는 5-23 kHz에 놓여 있다. 주파수 변조 패턴에 따라 대개의 unit들은 2타임으로 분류되나, 개체적 변이가 발견되었다. 새끼들의 소리는 개체마다 특징적으로 나타났다. (unit 수/call, 사용된 unit 유형, 주파수 범위 ); 이들의 전형적인 유형은 발달 과정을 통해 고유한 소리로 나타났다.

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Pressure fluctuation and characteristics of hydraulic jump downstream of a transversal structure for various Froude numbers (다양한 흐름조건에 따른 하천횡단구조물 하부의 도수특성 및 압력변동성 검토)

  • Yoo, Hyung Ju;Jeong, Seok il;Lee, Seung Oh
    • Proceedings of the Korea Water Resources Association Conference
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    • 2018.05a
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    • pp.63-63
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    • 2018
  • 최근 이상기후로 인한 국지성 호우의 발생빈도 및 강우강도의 증가는 하천횡단구조물의 안정성에 문제가 되고 있다. 하천 횡단구조물(보, 물받이공 등)의 파괴는 국부 세굴(bed scour), 파이핑(piping), 구조물 본체의 불안정성 등의 원인으로 발생되고 있으며, 이 중에서 구조물 본체의 불안정성은 도수(hydraulic jump)로 인한 압력변이도 주요 원인이 될 수 있다 (Bower and Toso, 1988; Kazemi, F. et al., 2016). 그러나, 현재 직접적인 파괴 원인인 세굴 등에 대한 연구에 비해 압력변이로 인한 구조물의 파괴원인을 분석하는 연구는 미비한 실정이다. 본 연구에서는 다양한 흐름조건을 발생시켜, 하천횡단구조물 주변의 도수특성 및 도수로 인한 압력변이에 대하여 수리실험 및 수치모의를 통하여 검토하고자 한다. 수리실험에 사용하는 수로는 길이 10 m, 폭 0.3 m, 높이 0.4 m이며 상류로부터 2.5 m 떨어진 곳에 보(weir)를 설치하였다. 실험조건은 다양한 흐름조건에 따른 도수 발생을 검토하고자 상하류 수위를 조절을 통해 Froude 수의 범위를 1 < Fr < 10로 설정하였다. 압력변이는 전압형 압력계(Model : UNIK 5000, 압력 측정 변위 : -2 ~ 5 kPa)를 사용하였으며, 보(weir) 하류단에서 2.5 cm 간격으로 천공하여 측정하였다. 또한 3차원 모형인 FLOW-3D 모형을 이용하여 실험수로를 재현하였으며, 도수 발생 위치, 도수 길이, 도수 발생 시 압력변이에 대하여 실험결과와 수치모의 결과를 비교하여 수치모형을 검증하였다. 최종적으로 Froude 수에 따른 도수특성(도수 발생위치, 도수 길이 등) 및 최대 압력변이를 무차원화 하여 나타내었다. 본 연구는 도수 발생 시 압력변이로 인한 구조물 파괴분석에 대한 기초가 되는 기본적인 연구이나, 향후에는 물받이공 길이, 두께 등 하천횡단 구조물 설계인자 도출에 선행연구로 발전할 수 있다고 판단된다.

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The Variation in Foliar Characteristics of Natural Population of Camellia japonica L. (동백나무 천연집단(天然集團)의 엽형질(葉形質) 변이(變異))

  • Kim, Yong Shik
    • Journal of Korean Society of Forest Science
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    • v.69 no.1
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    • pp.69-75
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    • 1985
  • These studies were carried out to know the variation of foliar characteristics of Camellia japonica distributed in Korea. The results are summarized as follows; 1) The values such as leaf length, leaf width, and leaf area were the most highest in Chukdo population, while the lowest in Chejudo population. 2) The values of Wando population showed the most highest in leaf serration characters, while the values of Kochang population the lowest. 3) In the number of cort warts, the values of Chundo population showed the most highest, while Dodcong population the lowest.

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Ecotypic Variation Related to the Ratio of Mannose to Galactose In the Seeds of Phaseolus angularis (팥(Phaseolus angularis) 종자에 함유된 mannose와 galactose의 함량비에 관한 생태형적 변이)

  • Kim, Chang-Ho
    • Journal of Life Science
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    • v.21 no.7
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    • pp.1060-1066
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    • 2011
  • In order to investigate the variations on the ratio of mannose to galactose in the seeds of Phaseolus angularis, 17 local strains (Yangyang, Pyeongchang, Ganghwa, Pocheon, Geumsan, Seocheon, Jincheon, Danyang, Tongyeong, Sancheong, Gumneung, Wolseong, Wando, Gokseong, Okgu, Jangsu, Bukjeju), which are located from $33^{\circ}15'N$ to $38^{\circ}11'N$, were selected according to their latitudes and geographical distances. The seeds of these strains were collected and their contents of mannose and galactose were analyzed. Mannose contents in the seeds were variable, ranging from 17.071 mg/g at its highest (Jangsu) and 6.488 mg/g at its lowest (Geumsan). The contents of galactose also showed remarkable differences, ranging from 9.477 mg/g (Wolseong) to 19.877 mg/g (Jangsu). The local strains were classified into 3 variation types - coastal type I (Wando, Okgu, Bukjeju), the inland type (Jangsu, Weolseong, Danyang, Geumneung, Pyeongchang, Sancheong) and coastal type II (Ganghwa, Seocheon, Tongyeong, Jincheon), as well as 4 strange strains (Gokseong, Yangyang, Pocheon, Geumsan) according to the geographical climatic type and the ratio of mannose to galactose, which indicate the hardness of seeds in Leguminosae and ranged from 0.64 to 1.22. The variation types are very significant genecologically as evidence for microevolution related to natural and artificial selection in cultivated plants.

Study on the Somatic Chromosome Numbers of Korean Aster L. and Its Allied Taxa (한국산 개미취속 및 근연 분류군의 체세포염색체수에 관한 연구)

  • 정규영
    • Korean Journal of Plant Resources
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    • v.10 no.4
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    • pp.292-299
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    • 1997
  • The somatic chromosome numbers among the various taxonomic characters about 17 taxa in Korean Aster and its allied taxa were investigated to review accurate scientific name and taxonomic rank. The somatic chromosome numbers of the treated taxa were invariable in same taxa, but variable among different taxa. The treated taxa were divided into two types by basic chromosome numbers, one type was x=9, the other x=8 and x=9 type was subdivided by polyploidy. The somatic chromosome numbers of Aster altaicus var. uchiymae, A. hyatae, Kalimeris chejuensis were reported firstly in this study, and based upon somatic chromosome numbers and leaf morphology, the plants, idenified as Aster pinnatifidus in Korea was considered variant of Kalimeris incisa.

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Development of Severity-Adjustment Model for Length of Stay in Hospital for Percutaneous Coronary Interventions (관상동맥중재술 환자의 재원일수 중증도 보정 모형 개발)

  • Nam, Mun-Hee;Kang, Sung-Hong;Lim, Ji-Hye
    • The Journal of the Korea Contents Association
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    • v.11 no.9
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    • pp.372-383
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    • 2011
  • Our study was carried out to develop the severity-adjustment model for length of stay in hospital for percutaneous coronary interventions so that we would analysis the factors on the variation in length of stay(LOS). The subjects were 1,011 percutaneous coronary interventions inpatients of the Korean National Hospital Discharge In-depth Injury Survey 2004-2006 data. The data were analyzed using t-test and ANOVA and the severity-adjustment model was developed using data mining technique. After yielding the standardized value of the difference between crude and expected length of stay, we analysed the variation of length of stay for percutaneous coronary interventions. There was variation of LOS in regional differences, size of sickbed and insurance type. The variation of length of stay controlling the case mix or severity of illness can be explained the factors of provider. This supply factors in LOS variations should be more studied for individual practice style or patient management practices and healthcare resources or environment. We expect that the severity-adjustment model using administrative databases should be more adapted in other diseases in practical.

Soil Salinity and Continuum Distribution of Vegetation on the Three Reclaimed Tidal Flats of Kyonggi-Bay in the Mid-West Coast of Korea (한국 중부 서해안 경기만 일대 3개 간척지의 토양 염농도와 식생의 연속분포)

  • Kim, Eun-Kyu;Chun, SoUl;Joo, Young-K.;Jung, Yeong-Sang;Jung, Hyeung-Gun
    • Korean Journal of Soil Science and Fertilizer
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    • v.41 no.2
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    • pp.83-93
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    • 2008
  • Assessing for flora distribution is necessary for land management and environmental research in reclaimed lands. This study was conducted to find out the relationship between vegetation distribution and soil salinity on three reclaimed tidal flats of Kyonggi-bay in the mid-west coast of Korea. We investigated the soil salinity and identified the vegetation at the continuum distribution spots, and describe the characteristics of continuum distribution. On the reclaimed tidal flats, spatial variation of vegetation formed partially, however as the result for connection of each spatial variation along with the soil salinity, continuum distribution formed and it was overlapped edaphic gradient with vegetation distribution, it means that the continuum distribution correspond with soil salinity gradient, as the evidence high salt tolerance species occurred at high saline spots, non salt tolerance species occurred at low saline spots. On the aged reclaimed tidal flats, continuum type was various and also clearly distinguished but it was not clear on the early stage of reclamation. The continuum distribution distinguished sequential and non-sequential type. Sequential type started from high saline zone and connected to low saline zone gradually, on this type, vegetation changed from pioneer halophyte to facultative halophyte and glycophyte along with the salinity gradient. Non-sequential type formed by non-sequential change of soil salinity, on this type, vegetation distribution was non-regular form because it has not changed gradually. In the aged reclaimed land, vegetation wilted zone existed with high salinity, and continuum distribution started from this zone with bare patch.