• Pediatric Infection and Vaccine
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• v.6 no.1
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• pp.101-106
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• 1999

Purpose : Tuberculosis, a major public health problem, is an important cause of childhood infectious diseases. To decrease the tuberculosis morbidity rate, BCG vaccination and chemoprophylaxis are performed. Recently 2TU PPD skin test was introduced as a diagnostic method for tuberculous infection. We studied the positive conversion rate of 2TU PPD test after percutaneous multiple puncture BCG vaccination. Methods : Four hundred seventy six infants from well baby clinic of Samsung Cheil Hospital were enrolled. They were immunized with percutaneous multiple puncture technique BCG(Japan BCG laboratory, Japan) at 1 month of age. Approximately 6 months later, tuberculin skin test using RT23 2TU PPD was performed. Induration size, family history of tuberculosis and number of BCG scars were evaluated. Induration greater than or equal to 5mm was defined as positive conversion. Results : Among 476 infants, 248(52.1%) were male and 228(47.9%) were female. PPD skin tests were performed $6.2{\pm}0.5$($mean{\pm}S.D.$) months after BCG vaccination. Mean induration size was $7.3{\pm}3.2mm$ and positive conversion rate was 85.5%. Total number of BCG scars was $15.5{\pm}3.2$. Conclusion : The seroconversion rate by 2TU PPD test after percutaneous multiple puncture BCG vaccination was high. But, more comparative studies with various age groups may be needed for 2TU PPD test used as diagnostic method of tuberculosis in the hospitals.

• Pediatric Infection and Vaccine
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• v.10 no.2
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• pp.153-158
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• 2003

Purpose : The incidence of hepatitis B virus infection has gradually decreased since 1983 when hepatitis B vaccine was firstly produced. This study was performed to evaluate the efficacy of hepatitis B immunization. Methods : The elementary, middle and high school children in Incheon area were enrolled in this study in 1997 and 1998. Hepatitis B virus surface antigen(HBsAg) was measured using reversed passive hemagglutination(RPHA). Results : The results were as follows The positive rates of HBsAg in elementary, middle and high school children were 0.7%(337/46,861), 2.5%(381/15,026) and 3.1%(681/21,938) respectively in 1997 and 0.6%(257/41,946), 2.7%(379/13,652) and 2.4%(628/25,277) respectively in 1998. The positive rates of HBsAg in children under 19 years of age in 1985, 1990 and 1995 were 6.1, 5.2 and 3.5% respectively. Conclusion : The positive rates of HBsAg in elementary school children in 1997 and 1998 has decreased compared with those of the previous studies. The majority of elementary school children were given hepatitis B vaccination. These results suggest that hepatitis B vaccines used in Korea were effective for prevention of hepatitis B infection in school children.

• Korean Journal of Microbiology
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• v.44 no.3
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• pp.221-227
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• 2008

Bordetella pertussis is pathogenic bacteria causing pertussis, a infectious respiratory disease for the infants. The incidence rate of pertussis was significantly decreased after introduction of vaccine. However, increased pertussis cases are recently reported in several countries with high vaccine coverage. One of the inferred reasons is genotype or serotype variation between circulating strains and vaccine strains. Therefore, it is required to confirm the variation status of the isolates by genotype or serotype analysis and the possibility of pertussis outbreak in Korea should be estimated. For this, the serotype variations of the isolates from $1999\sim2006$ were investigated in agglutinogen and fimbriae. As the result, the most frequent serotype in the isolated strains was agglutinogen 1 and fimbriae 2 serotypes. Moreover, serotype transition from vaccine serotypes to non-vaccine serotypes was observed. Especially, the transition pattern of agglutinogen serotype was directed to increase a different type (agg 1) from the vaccine type (agg 1,2). However, in case of fimbriae, the same type (fim 2) with vaccine strain was increased. These results were also observed in other countries with increasing incidence of pertussis. For more predictable results to know increasing possibility of pertussis incidence in Korea, the studies on genetic variations of antigenic determinant genes and prevalence of antibody titer in normal population should be performed in the further.

• KOREAN POULTRY JOURNAL
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• v.39 no.1 s.447
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• pp.107-109
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• 2007

본고는 일본에서 AI로 인해 2004년에 이어 2006년 또 다시 540만수를 대량 살처분함에 따라 감염이 되지 않은 대단위 농장의 피해를 최소화하고 보다 효율적인 예방대책을 모색하기 위하여 일본양계협회, 일본수의학회, 일본계란생산자협회가 2006년 8월 9일(水) 동경 오꾸라호텔에 서 공동 주최한‘조류인플루엔자에 대한 일본의 방역대책’에 대해 국제수의사무국(OIE) 명예고문이며 일본AI방역대책에 각종 제안과 조언을 하고 있는 오자와(小洋義傳) 박사가 발표한 내용을 방역당국과 농가들에 참고자료로 활용코자 발췌·번역·게재한 것이다. 이 내용을 발표한 오자와 박사는바이러스, 수의역학을 전공하고 국제식량농업기구(FAO), 국제수역사무국(OIE), OIE아시아, 대서양지역 대표를 거친 가축전염병대책에 국제적 권위를 인정받고 있다

• 대한예방의학회:학술대회논문집
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• 2001.10a
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• pp.294-295
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• 2001

• Journal of Veterinary Clinics
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• v.17 no.1
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• pp.52-56
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• 2000

The objective of this study was to compare occurrence of the shipping fever associated with vaccination and mass medication in Korean Native Cow. Lack of vaccination (Pasteurella haemolytica, infectious bovine rhinotracheitis, bovine viral diarrhea, parainfluenza 3, and bovine respiratory syncytial virus) and mass medication before and after transportation, 67% of gram-negative cocci were detected. However, with vaccination and mass medication, only 33% of Gram-negative cocci were detected. When antimicrobial susceptibility for the detected bacterium was tested, apramycin, ampicillin, amilacin, clindamycin, gentamycin, kanamycin, penicillin, and streptomycin were resistant, whereas tylocin, amoxicillin, linocospetin, nalidixic acid, norfloxacin, oxalinic acid, and cefotaxime were susceptible. Morbidity and average therapeutic effect were 33% and 1.0time with vaccination and mass medication and were 78% and 5.3 times without vaccination and mass medication, respectively. Therefore, the results suggest that shipping fever would be considerably decreased with vaccination including mass medication before and after transportation.

• Korean Journal of Poultry Science
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• v.18 no.3
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• pp.209-218
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• 1991

An experiment was conducted to examine the efficacy of spray vaccination against Newcastle disease (ND). Four different coarse sprayers and four different diluents were compared in particle size, immune response and respiratory reaction. The smaller particle size of sprayer was, the better efficacy was and the more respiratory reactions were appeared. Of four diluents, antibody responses and resistance to challenge were higher with skim milk and gelatin, respectively .When day-old broiler chicks with maternal antibodies were vaccinated by coarse. sprayer B with B$_1$strain diluted in 1% skim milk, they showed 100% protection at two weeks of age and 50% from 4 to 8 weeks of age. Another group which boostered at 2 weeks of age by drinking water vaccination showed 100%, 70%, 50%, 40% protection at 2, 4, 6, 8 weeks of age, respectively. Although spray vaccination against ND in this experiments showed similar efficacy, compared to conventional methods, this method may not be appropriate in our field condition because of respiratory vaccinal reaction.

• 사료
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• s.69
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• pp.14-17
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• 2014

${\Box}$ 제82차 세계동물보건기구(OIE) 총회가 지난 5월 24일~5월 30일까지 프랑스에서 158개국 500여명이 참석한 가운데 개최 ${\bigcirc}$ 총회에는 WHO, FAO 등 국제기구와 함께 브라질, 독일 등 41개국 장관 및 차관 등 고위급 인사 참석 ${\Box}$ 우리나라는 농림축산식품부(이하 농식품부) 차관보를 단장으로 대표단을 구성하여 현지 대응 등을 통해 OIE 총회에서 구제역(FMD), 소해면상뇌증(BSE, 일명 광우병) 등 4개 질병 청정국 지위를 획득함 ${\bigcirc}$ 4개 질병 청정국은 구제역(백신접종 청정국), 소해면상뇌증(위험무시국), 가성 우역 아프리카마역(청정국) ${\Box}$ 구제역, BSE 등 청정국 지위획득은 우리나라 축산물의 안전성에 대한 신뢰성 제고, 수출가능성 확대 등 효과가 기대됨 ${\Box}$ 농식품부는 청정국 획득만큼이나 앞으로 청정국 유지가 중요하다고 강조하면서, 축산농가 및 국민들의 지속적인 방역 협조를 당부함.

• The Korean Chronic Disease News
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• no.322
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• pp.1-18
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• 2007

은퇴의사 보건소 봉사체계 도입/내년부터 병원 등 전면파업 금지/노인요양병원 30곳 종합실사/한국인 혈당 기준 대폭 강화/흡연이 40대 발기부전 직접 원인/노인 성병 감염자 대책 절실/복강경 대장수술 97%가 대장암/이화의료원, 여성전문대학병원 재도약/베트남에 한양대 류마마티스 센타 설립/김안과, 범태평양 안과병원 네트워크 구축/약제비절감 의사에 인센티브 제공/의약품 표준코드 시행 1년 유예 요청/전 국민 살빼기 캠페인/자궁경부암 백신, 45세까지 접종 확대/제약협회와 긴밀한 관계 유지/만성폐쇄성폐질환(COPD) 환자 급증/흡연, 음주가 대사증후군 2배 높여/골다공증에 대한 이해 여전히 부족/표준체중 성인도 '복부비만' 주의/녹차, 충치 예방과 치아 착색의 양면성/마음을 여는 Heart행정 실현-충주시보건소/'열심, 합심, 양심', 三心행정 지향/만성질환관리의 정책적 추진 방향/

• Monthly Duck's Village
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• s.65
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• pp.49-56
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• 2008

대만정부는 1968년도에 오리에 대한 체계적인 연구를 수행할 수 있도록 연구소를 설립하여 오늘날 5개의 연구서에서 수많은 석박사가 육종, 질병, 영양, 관리에 이르기까지 체계적인 연구를 하고 있고 농민들은 이들의 기술적인 지원과 교육을 받아 오리알과 고기를 효율적으로 생산함은 물론 전체 생산량의 약 40% 가량을 일본에 수출하여 외화소득을 올리고 있었다. 한국처럼 단순히 종압(종자용 어미오리)을 수입하여 병아리를 부화 생산하는 단계를 넘어서 육종을 활발히 하여 건강하고 경제적인 오리를 기르고 있었다. 우리나라에서 큰 문제가 되고 있는 질병인 오리 혈증 바이러스성 간염, 바이러스성 장염은 별로 큰 문제가 되지 않고 가금콜레라(양계의 C.R.D와 유사)가 첫번째 중요질병이라고 하는 등 질병 발생양상도 크게 차이가 있었다. 바이러스 간염의 경우 대만은 백신을 접종하여 거의 100% 예방하고 있는데 우리나라는 아직 개발완료 단계인 것으로 알려지고 있다.