• Women's Health Nursing
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• v.20 no.1
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• pp.105-114
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• 2014

Purpose: The goal of this study was to examine knowledge level of human papillomavirus (HPV), cervical cancer, and vaccination status among Korean mothers' with a daughter in high school. Methods: A cross-sectional descriptive study was conducted with a convenience sample of 234 Korean mothers. Results: The mean score of HPV knowledge level was 4.21 out of 20, and cervical cancer knowledge was 3.88 out of 7. There were low levels of daughters' who received HPV vaccination (3.8%) and high levels of mothers' intention to get their daughters' vaccinated with HPV (85.0%). The major barrier to HPV vaccination was the concern for side effect from the vaccination. The most effective recommendation for HPV vaccination came from health care providers. Conclusion: HPV educational programs targeting mothers of daughters in high school is needed. Future studies need to determine actual HPV vaccination rates and factors related to high uptake using a larger sample from various socioeconomic background.

• Women's Health Nursing
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• v.24 no.1
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• pp.71-79
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• 2018

Purpose: The purpose of this study was to identify effects of attitude, subjective norm, and perceived behavior control toward Human Papillomavirus (HPV) on HPV vaccination intention in female high school students. Methods: Subjects of this study were female students aged 16 to 17 years, the optimal age group of HPV vaccination, arbitrarily selected from three high schools in B city. A total of 140 students agreed to participate in this study. Data were analyzed using descriptive statistics, t-test, ANOVA, correlation, and stepwise multiple regression. Results: Attitude, subjective norm, and perceived behavior control toward HPV were factors influencing HPV vaccination intention of subjects. Perceived behavior control toward HPV vaccination was the most influential factor. These factors accounted for 49% of HPV vaccination intention. Conclusion: These results suggest a need to increase perceived behavior control to increase HPV vaccination intention. The government needs to establish a national policy system such as financial support for HPV vaccines and free vaccinations so that students are aware that HPV vaccines can be easily inoculated.

• Child Health Nursing Research
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• v.25 no.4
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• pp.458-467
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• 2019

Purpose: The purpose of this study was to identify human papillomavirus (HPV) vaccination research trends by visualizing a keyword network. Methods: Articles about HPV vaccination were retrieved from the PubMed and Web of Science databases. A total of 1,448 articles published in 2006~2016 were selected. Keywords from the abstracts of these articles were extracted using the text mining program WordStat and standardized for analysis. Sixty-four keywords out of 287 were finally chosen after pruning. Social network analysis using NetMiner was applied to analyze the whole keyword network and the betweenness centrality of the network. Results: According to the results of the social network analysis, the central keywords with high betweenness centrality included "health education", "health personnel", "parents", "uptake", "knowledge", and "health promotion". Conclusion: To increase the uptake of HPV vaccination, health personnel should provide health education and vaccine promotion for parents and adolescents. Using social media, governmental organizations can offer accurate information that is easily accessible. School-based education will also be helpful.

• Journal of Korean Academic Society of Home Health Care Nursing
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• v.27 no.3
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• pp.284-293
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• 2020

Purpose: Based on Anderson's model of health service utilization, we investigated the factors that affect the influenza vaccination status in Korean adults aged 50-64 years, who live alone. Methods: Data of 194 Korean adults aged 50-64 years, who live alone were obtained from the Korea National Health and Nutrition Examination Survey 7th Edition (2016-2018). Descriptive statistics and a multiple logistic regression model were used for statistical analysis. Results: The influenza vaccination rate in the study population was 39.3%. Educational status and health behaviors such as smoking habits and regular medical check-up were associated with the influenza vaccination rate in Korean adults aged 50-64 years, who live alone. Multiple logistic regression analysis showed that educational level lower than middle school graduation (odds ratio [OR] 2.02), non-smoking status (OR 1.98), and lack of regular medical check-up (OR 0.62) were significantly associated with the influenza vaccination rate in Korean adults aged 50-64 years, who live alone. Conclusion: The influenza vaccination rate in Korean adults aged 50-64 years, who live alone, is relatively low; therefore, policies should be implemented to improve the influenza vaccination rate in this population. Influenza vaccination in single households was affected by health promotion activities; therefore, interventions are warranted to encourage overall health promotion activities.

• The Journal of the Convergence on Culture Technology
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• v.8 no.2
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• pp.109-116
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• 2022

This study conducted YouTube network analysis on YouTube video related with prevention of COVID-19 and COVID-19 vaccine to explores how government's policy is spread via social media in the condition of COVID-19. As a result of network analysis on the Mask chaos, A surge in confirmed cases, supply of vaccine, the influence of media like YTN and KBS is large, their view count is high. Government highlights to inform correct information actively to face negative massage and misinformation. The media has to fact check on the misinformation and disinformation.

• Journal of Digital Convergence
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• v.19 no.9
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• pp.229-239
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• 2021

This study is to identify the factors influencing the attitudes, behavior controls, and subjective norms related to COVID-19 vaccination on the intention of preventive behavior in K provincial residents. A total of 232 people agreed to participate in the study. Data were analyzed using descriptive statistics, t-test, ANOVA, correlation, and Hierarchical analysis. As a result of this study, the factors that had a statistically significant effect on the intention to conduct COVID-19 vaccination were perceived behavioral control (β=.39, p<.001) and attitude toward COVID-19 preventive behavior (β=.24, p<.001), followed by subjective norm (β=.24, p<.001). The explanatory power for this was 56.8%. The COVID-19 vaccine is an important means of ending the COVID-19 pandemic and helps prevent infection or worsening of COVID-19 and protect those around you. In the post-COVID-19 situation, it is necessary to improve the intention of vaccination against COVID-19 and to take active measures and strategies. At this point in time when COVID-19 vaccination is becoming more prevalent across the country, we hope that the intent of the COVID-19 vaccination action will translate into a COVID-19 vaccination action.

• Pediatric Infection and Vaccine
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• v.5 no.1
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• pp.88-95
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• 1998

Purpose : Varicella is a common contagious illness and vaccine against it has been used in healthy Korean children. We studied clinical and epidemiologic features of varicella and the effect of vaccination. Methods : We analyzed clinical and epidemiologic features of varicella and vaccination effect against it in children treated in Hangang Sacred Heart Hospital from March 1994 to December 1996. Results : 1) Total 73 cases of varicella, 46 male and 27 female patients were included. Annual incidence was 31, 20 and 22 cases from '94 to '96 respectively, with an increase during the period June to July and December to January. 2) Mean age was $46{\pm}37.2$ months and 84.9% of the patients were younger than 7 years old including 16.4% of infants. 3) Varicella occurred after a contact with varicella patients in 40(54.8%) patients. 4) Fever developed in 44(60%) patients with mean $38.4{\pm}0.8^{\circ}C$ and persisted for mean $3{\pm}2.4$ days. Nine(12.3%) patients had complications and eighteen(25%) patients were admitted for mean $4{\pm}2.1$ days but all recovered. 5) Twenty(27.8%) patients were affected despite preceding vaccination against varicella but the number of vesicles decreased significantly in vaccinees(P<0.01). 6) The rate of secondary cases in healthy siblings was 27 out of 35(77.1%) and was not affected by preceding vaccination. Conclusion : Varicella occurred mainly in children younger than 7 years old and showed seasonality. Because 27.8% of cases developed despite preceding vaccination and the rate of secondary cases was not affected by vaccination, further study for vaccine efficacy is necessary.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2004.11a
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• pp.23-25
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• 2004

This study was conducted to investigate the effects of dietary supplementation of Ecklonia cava kjellman(ECK) and crude lectin extracted from ECK (CLEEC) on performances and immune responses in broiler chicks. A total of two hundreds thirty four 1 day old male broiler chicks (Ross) were fed corn-soy based diets containing 0 % (with or without vaccination and Salmonella challenge), 1.0 % ECK, 0.05 %, 0.1 % and 0.3 % CLEEC for 38 days and vaccinated against inactivated ND-IB combined oil vaccine on the fourth day. After S. gallinarum challenge. mortality was measured daily. The spleens of birds were removed for RNA extraction and reverse transcription polymerase chain reaction (RT-PCR) with primer sets for IFN-ν, IL-2, IL-6 and ${\beta}$-actin were performed with RNA samples. At the 28th day, pancreas weights were heavier 0.3 % CLEEC than 1.0 % ECK group. At the 21st day after ND-IB oil vaccine injection, dietary supplementation of ECK and CLEEC tended to increase or significantly (P<0.05) improved ND or IB titer compared to the positive control. Mortality was significantly (P<0.05) decreased by dietary CLEEC treatments. Chicken splenic IFN-ν, IL-2, and IL-6 cytokines mRNA expressions were enhanced by challenge with S, gallinarum. Dietary treatments did not affect mRNA expression of IFN-ν. However, IL-2 and IL-6 expressions in Salmonella challenged birds that fed the 1.0 % ECK or 0.05 % CLEEC groups were enhanced (P<0.05) compare to the positive control. The results demonstrated that dietary ECK and CLEEC enhanced humoral and cellular immunity and therefore. it can be concluded that dietary supplementation of ECK and CLEEC can be used as a feed additive for enhancement of immunocompetence without any adverse effects in broiler chicks.

• Journal of Fisheries and Marine Sciences Education
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• v.27 no.3
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• pp.672-681
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• 2015

Edwardsiellosis has become a serious diseases problem in cultured eels for many years. This study was performed to investigate possibility of vaccination against edwardsiellosis caused by Edwardsiella tarda. We conducted a immersion and/or oral vaccination using formalin-killed E. tarda in eel Anguilla japonica. Three groups of fish ($26.8{\pm}1.2g$, $7.1{\pm}0.7g$ and $2.2{\pm}0.4g$) were used in this study. The protection (relative percentage survival, RPS) and serum antibody response (agglutination titer) were evaluated in the vaccinated fish. No correlation between agglutination titer and survival rate was observed in vaccinated fish. However, there was a satisfactory protective (RPS>50%) in vaccinated fish. Immersion (10 mg/mL, 1 hr) and immersion (10 mg/mL, 1 hr) plus oral (10 mg/g, 10 days) of $26.8{\pm}1.2g$, immersion (10 mg/mL, 1 hr) plus oral (10 mg/g, 10 days) of $7.1{\pm}0.7g$ showed RPS of 62.6%, 52.2% and 56.8%, respectively.

• Korean Journal of Microbiology
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• v.43 no.1
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• pp.7-13
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• 2007

Pasteurella multocida is one of the important animal pathogen causing widespread infections in various domestic animals. In swine, it causes severe respiratory diseases such as atrophic rhinitis and pneumonic pasteurellosis. To develop the efficient subunit vaccine against swine atrophic rhinitis, we investigated protective antibodies and humoral immunity of outer membrane protein H (OmpH) which is one of the major outer membrane proteins in P. multocida. Outer membrane fraction of P. multocida was immunologically detectable using antisera from both mice groups vaccinated by formalin-killed whole cells and by commercial vaccine. The expression vector for production of recombinant OmpH was constructed and the recombinant OmpH was expressed and purified from E. coli. Recombinant OmpH showed high antigenic and immunogenic properties in mice vaccination and ELISA with antisera.