• Proceedings of the Korea Contents Association Conference
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• 2011.05a
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• pp.187-188
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• 2011

저 에너지 방사선검사 시 부득이하게 방사선 노출을 받게 되는 방사선 작업종사자나 환자의 보호자가 위치와 거리에 따른 방사선 피폭 선량의 감소 방안을 알아보고자 한다. Ion chamber mode 2026c, Reader기 20X6-1800을 사용하여 구강내 검사와 구강외 검사의 각각 검사실과 조정실에서의 관전압의 변화, 관전류와 조사시간의 변화, 조사방향의 변화에 따라 선량을 측정하였다. 그 결과 검사실 안에서는 최고선량이 평균 $702.8{\mu}R$으로 측정 되었으며, 조정실 안에서 측정하였을 경우 $20{\mu}R$이하의 낮은 선량을 보였으며, 후방검사보다 측방검사가 낮은 선량으로 나타났다. 방사선검사 시 위치와 거리에 따른 조사선량을 비교 분석하여, 적절한 거리 확보와 조사되는 중심방사선을 기준으로 측방($90{\sim}135^{\circ}$)에 위치함으로써 방사선 방어에 도움을 줄 것이며, 차폐문을 이용하여 방사선 피폭으로부터 감소 효과를 볼 수 있을 것이다.

• Journal of radiological science and technology
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• v.41 no.5
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• pp.471-478
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• 2018

Oogenesis process of ovary produces a lot of undifferentiated cells. Especially, the radiation exposure of early immature cells in the process of growth to oocyte causes serious disabilities. This study examined the radiation damage mechanism of undifferentiated cells and organelles in oogenesis process, and the radioprotection after injection of alliin. The ultrastructure after 7Gy X-ray irradiation on the white rat was observed in the experiment. The results is as follows. It was observed that the nucleus membrane of an oogonium was damaged and vacuolated in the several parts after 15 days of irradiation. The damage of mitochondria membrane and flow in cytoplasm after 20 and 30 days was found in the oogonium. After 40 days observation, peroxidation of fat droplets was found and organelles were tangled each other in ovary tissue. The partial damage of nuclear membrane in oogonium past 15 days after injection of alliin was found, but decreased remarkably. Mitochondria, Golgi body, and rough endoplasmic reticulum were also clearly observed, therefore, radioprotection effects in alliin was confirmed partially.

• Journal of radiological science and technology
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• v.31 no.1
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• pp.49-54
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• 2008

After x-ray 5Gy radiation on the whole body of a mouse using a linear accelerator, its leucocyte, erythrocyte, and platelet were observed by SEM. Also, after injecting propolis into the abdominal cavity, the radio-protective effect of blood corpuscles was studied. The observation of micromorphology in blood corpuscles revealed that the number of leukocyte, erythrocyte, and thrombocyte decreased in the experimental group and the lump got together in blood corpuscles after 10 and 20 days. In RBC, crack or break on the surface and poikilosperocytes were observed. In the irradiation group, the size of leucocytes was smaller than that in control group and the number of villus at the verge substantially decreased. The blood corpuscles in the propolis group, however, had the similar results to control group.

• Journal of radiological science and technology
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• v.27 no.2
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• pp.35-43
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• 2004

Radioprotective effects of ginseng extracts on liver damage induced by high energy x-ray were studied. To one group of ICR male mice were given white(50 mg/kg/day for 7days, orally) and fermenta ginseng extracts(500 mg/kg/day for 7days, orally) before irrdiation. To another group were irradiated by 5 Gy dose of high energy x-ray. Contrast group were given with saline(0.1 ml). This study also investigated the radioprotective effect between SOD, CAT, hydrogen peroxide and ginseng extracts on hepatic damage. This study measured the level of superoxide dismutase(SOD), catalase(CAT), hydrogen peroxide($H_2O_2$) in liver tissue. Administrating orally white (50 mg/kg/day for 7days, orally) and fermenta ginseng extracts(500 mg/kg/day), the activity of SOD, CAT were generally increased and the hydrogen peroxide($H_2O_2$) was decreased. After irradiation, the activity of SOD, CAT were generally decreased and the hydrogen peroxide($H_2O_2$) was increased. Therefore, ginseng extracts increased antioxidative enzyme activity. And We know that the antioxidatant effect of extracts from white and fermenta ginseng protect radiation damage by direct antioxidant effect involving SOD, CAT. It was included that ginseng can protect against radiation damage through its antioxidatant properties.

• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.5
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• pp.605-612
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• 2005

In previous studies, we evaluated the effect of the 6 energy-tonic or blood-building prescriptions of traditional oriental medicine, and observed that Si-Wu-Tang and Bu-Zhong-Yi-Qi-Tang showed high activity in the protection of the gastrointestinal and hematopoietic organs in irradiated mice. But any of these prescriptions did not show a high activity in the activation of the immune cells. We performed this study to design an herb mixture which protects the self-renewal tissues and also promotes recovery of the immune system against radiation damage. In order to meet all the requirements, we designed a new mixture of 3 edible herbs listed in Korean Food Code. The mixture of Angelim gigas radix, Cnidium officinale rhizoma and Paeonia japonica radix was decocted with hot water, and the activities of the water extract (HIM-I) were evaluated. HIM-1 stimulated the immune cells in a much higher extent than the traditional prescriptions, and promoted dramatically the growth of bone marrow stem cells in vitro. Also, HIM-1 protected digestive and hematopoietic organs against radiation as effectively as the 2 prescriptions, Si-Wu-Tang and Bu-Zhong-Yi-Qi-Tang. On the other hand, it showed high in vitro antioxidative activity that might be considered as a mechanism of the protective effects against radiation. Although the detailed mechanisms of those effects remain to be elucidated, these results indicated that HIM-I might be a useful agent for protection and recovery of body from various risk factor as well as radiation, especially since it is a relatively nontoxic natural product.

• The Journal of Korean Society for Radiation Therapy
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• v.9 no.1
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• pp.1-7
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• 1997

다량의 방사선에 피폭되는 경우 인체에 해로운 영향을 미치는 것은 틀림이 없으나 미량의 방사선인 경우에는 다량의 방사선인 경우와 다른 효과를 나타내며 심지어 정반대의 영향을 나타내기도 한다고 볼 수 있으며 여러 역학조사에서 이러한 사실이 증명되고 있다. 1991년의 국제방사선방어기구(ICRP) 보고서 및 1994년의 UNSCEAR 보고서는 미량의 방사선에 대한 적응반응을 인정하고 있다. 일부 학자들은 소량의 방사선에 지속적으로 피폭(연간 1 rem)됨으로써 암사망률을 감소시킬 수 있다고 주장하면서 현재의 개념을 수정하여 피폭한계 및 법적 제한 등을 변경하여 환경방사능을 증가시킴으로써 향후 인류의 생활의 질을 향상시켜야 한다고 주장하고 있다.

• Journal of Radiation Protection and Research
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• v.20 no.3
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• pp.169-179
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• 1995

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.1
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• pp.22-27
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• 2004

In the present study, the protective effects of Artemisia capillaris (AC) on the DNA damage induced by $^{60}$ Co ${\gamma}$-rays were evaluated using alkaline single-cell gel electrophoresis (SCGE, comet assay) in the mouse peripheral lymphocytes and micronuclei (MN) formation test in the Chinese hamster ovary (CHO) cells. We also investigated the effect of AC on 8-hydroxy-2'-deoxyguanosine (8-OHdG) formation in the mouse liver and thymus exposed to ${\gamma}$-ray, The tail moment and the frequency of MN, which were markers of DNA damage in the SCGE and MN formation test, were decreased in the groups treated with AC extract before exposure to 200 cGy of ${\gamma}$-ray. We also observed its activities, lowering 8-OHdG level, an index of oxidative DNA damage, in the groups treated with AC extract before whole body ${\gamma}$-irradiation (800 cGy). It is plausible that scavenging of free radicals by AC may have played an important role in providing the protection against the radiation-induced damage to the DNA. These results indicated that AC protects the DNA damage induced by ${\gamma}$-rays and might be a useful radioprotector, especially since it is a relatively nontoxic product.

• Journal of the Korean Society of Radiology
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• v.17 no.4
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• pp.497-506
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• 2023

In the case of radiation workers in medical institutions, radiation exposure is made for patient protection and accurate procedures, so they have a problem of low dose exposure. Low-dose radiation exposure occurs mainly in parts of the body other than the Apron area, and the most frequent place is the skin of the back of the hand. In particular, since the medical personnel's hands require senses and fine movements during the procedure, they are defenseless in the radiation exposure area and are at risk of exposure. It can solve the problem of shielding such as lead gloves, and it is difficult to use by suggesting the activity of the hand during the procedure. To solve this problem, a shielding cream capable of obtaining a functional radiation protection effect was developed and its shielding performance was compared with lead equivalent of 0.1 mmPb. In the process of manufacturing shielding cream, the shielding performance was improved by adding a defoaming process to reduce air holes to increase the density of the cream. Therefore, the shielding cream using barium sulfate as the main material has a lower shielding rate than the lead plate, and in the realm of effective energy, it is 59%, At high effective energy, a difference of about 37% was shown, indicating that there is a functional radiation protection effect. The advantage is that it can be used directly on the skin, and it is considered that it can be used before wearing surgical gloves and has a permanent protective effect.

• Journal of the Korean Society of Radiology
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• v.16 no.5
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• pp.527-536
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• 2022

The radiation shielding characteristic of neutron shielding material has been studied as the preliminary study in order to design cosmic-ray shielding material. Specially, Soft Magnetic Material, known to be effective in EMP and radiation shielding, has been investigated to check if the material would be applicable to cosmic-ray shielding. In this work, thermal neutron shielding experiment was conducted and the Monte Carlo N-Particle(MCNP) was applied to employ skymap.dat, which is cosmic-ray data embedded in MCNP. As a result, polyethylene, borated polyethylene, and carbon nano tube, containing carbon or hydrogen, have been found to be effective in reduction of neutron flux below 20 MeV (including thermal, epithermal, evaporation). In contrast, the materials composed of iron such as SS316 and Soft Magnetic Material show a good shielding performance in the cascade energy range (above 20 MeV). Since Soft Magnetic Material is consisting of 13% of boron, it can also decrease thermal neutron flux, so it is expected that it would show a significant reduction on the entire range of neutron energy if the Soft Magnetic Material is used with hydrogen and carbon, so called low Z material.