• Title/Summary/Keyword: 반응성 상호작용

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이달의 과학자 - 서울대 역학과 교수 정진호박사

  • Korean Federation of Science and Technology Societies
    • The Science & Technology
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    • v.29 no.5 s.324
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    • pp.76-77
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    • 1996
  • 염소소독을 한 수돗물에는 THM이란 오염물질이 잔류하게 되는데 간독성을 유발하는 이 HTM이 신장에도 독성을 일으킨다는 사실을 밝혀낸 서울대 약학과 정진호교수가 이달의 과학자로 뽑혔다. 최근 혈소판도 화학물질에 의해 독성반응을 일으킨다는 사실을 세계 최초로 밝혀낸 정교수는 혈소판과 혈관의 상호작용에 대한 연구로 분주한 나날을 보내고 있다.

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The neural mechanism of distributed and focused attention and their relation to statistical representation of visual displays (분산주의와 초점주의의 신경기제 및 시각 통계표상과의 관계)

  • Chong, Sang-Chul;Joo, Sung-Jun
    • Korean Journal of Cognitive Science
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    • v.18 no.4
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    • pp.399-415
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    • 2007
  • Many objects are always present in a visual scene. Since the visual system has limited capacity to process multiple stimuli at a time, how to cope with this informational overload is one of the important problems to solve in visual perception. This study investigated the suppressive interactions among multiple stimuli when attention was directed to either one of the stimuli or all of them. The results indicate that suppressive interactions among multiple circles were reduced in V4 when subjects paid attention to one of the four locations, as compared to the unattended condition. However, suppressive interactions were not reduced when they paid attention to all four items as a set, in order to compute their mean size. These results suggest that whereas focused attention serves to later out irrelevant information, distributed attention provides an average representation of multiple stimuli.

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A Literature Review on Studies of Bentonite Alteration by Cement-bentonite Interactions (시멘트-벤토나이트 상호작용에 의한 벤토나이트 변질 연구사례 분석)

  • Goo, Ja-Young;Kim, Jin-Seok;Kwon, Jang-Soon;Jo, Ho Young
    • Economic and Environmental Geology
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    • v.55 no.3
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    • pp.219-229
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    • 2022
  • Bentonite is being considered as a candidate for buffer material in geological disposal systems for high-level radioactive wastes. In this study, the effect of cement-bentonite interactions on bentonite alteration was investigated by reviewing the literature on studies of cement-bentonite interactions. The major bentonite alteration by hyperalkaline fluids produced by the interaction of cementitious materials with groundwater includes cation exchange, montmorillonite dissolution, secondary mineral precipitation, and illitization. When the hyperalkaline leachate from the reaction of the cementitious material with the groundwater comes into contact with bentonite, montmorillonite, the main component of bentonite, is dissolved and a small amount of secondary minerals such as zeolite, calcium silicate hydrate, and calcite is produced. When montmorillonite is continuously dissolved, the physicochemical properties of bentonite may change, which may ultimately causes changes in bentonite performance as a buffer material such as adsorption capacity, swelling capacity, and hydraulic conductivity. In addition, the bentonite alteration is affected by various factors such as temperature, reaction period, pressure, composition of pore water, bentonite constituent minerals, chemical composition of montmorillonite, and types of interlayer cations. This study can be used as basic information for the long-term stability verification study of the buffer material in the geological disposal system for high-level radioactive wastes.

The Interrelationship of Infant-Mother Interaction and Early Social Communication Skills (영아-어머니의 상호작용 방식과 영아기 사회적 의사소통능력)

  • Kwak, Keumjoo;Kim, Minhwa;Hahn, Eun Joo
    • Korean Journal of Child Studies
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    • v.25 no.5
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    • pp.111-128
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    • 2004
  • Responsiveness and initiative between infant and mother from toy centered play situation at 6, 7 months of age and infant's social communication skills at 12 months were studied in a sample of 62 infant-mother pairs. Through the video analysis, infants were grouped into simple react group, cooperated group, and active initiative group. In the between groups, we analyzed whether mother's initiative act styles and response styles were different, and whether their social communication skills were different when they tested at 12 months. The results showed that mother's initiative styles were not different but mother's response styles were significantly different with infant groups. Further result showed that cooperated group gained higher score than active initiative group in the total score of Eary Social Communication Skills scales at 12 months of age. The results suggested that mother's responsive behaviors were more important than initiative behaviors for the infant's positive interaction, and the difference of these behaviors would lead to a gap of early social communication abilities.

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The Effects of Perceived Risk and Interactivity on User's Satisfaction and Commitment in Personal Media (1인 미디어의 지각된 위험 및 상호작용성이 사용자 만족과 몰입에 미치는 영향)

  • Chung, Young-Soo;Jung, Chul-Ho
    • Management & Information Systems Review
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    • v.28 no.1
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    • pp.125-156
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    • 2009
  • The primary purpose of this study is to identify the determinants of the users' satisfaction and commitment in personal media. For these purposes, we developed a research model based on the literature reviews of personal media, perceived risk and interactivity, satisfaction, and commitment. This study has identified four dimensions in the concept of perceived risk, such as privacy risk, social risk, time loss risk, and economic risk, and three dimensions in the concept of perceived interactivity, such as active control, two-way communication, and responsiveness. In survey, data were collected from 428 male and female who have an experience in personal media. Data was analyzed factor analysis, reliability analysis, measurement model analysis, and structural model analysis by utilizing SPSS 15.0 and AMOS 5.0 program. Analysis results of research model indicate the following. Firstly, privacy risk, active control, two-way communication, and responsiveness are significantly related satisfaction. Secondly, privacy risk, time loss risk, economic risk, active control, and two-way communication are significantly related commitment. Thirdly, users' satisfaction has positive relationship with commitment in personal media. Based on these results, theoretical implications for relevant researchers and managerial implications for personal media vitalization and marketing strategy are discussed. Finally, limitations for this study and further research issues are suggested.

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The long-term effect of Interactive Video Game on Cognitive Information Processing the elderly: P300 (장기간의 상호작용적 비디오 게임이 노인의 인지정보처리에 미치는 영향: P300)

  • Kim, Sung-Woon;Kim, Han-Cheol
    • Journal of Digital Convergence
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    • v.18 no.8
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    • pp.493-504
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    • 2020
  • The objectives of this study was to examine the effect of Interactive Video Game on cognitive information processing the elderly. Sixty elderly were attended in this study. Their ages ranged from 65 to 70, with a mean age of 67.60 years. The subjects were randomly assigned to one of three experimental conditions: (1) interactive video game group (n=20), (2) aerobic exercise group (n=20), (3) control group (n=20). The experimental design of this study was analyzed using two-way ANOVAs with repeated measures of groups and time. Cognitive function was assessed by neuroelectrical response, and ERP analysis. The results of the study showed that the interactive video game group and aerobic exercise group showed no significant statistical differences in the response time, response accuracy, amplitude and potential of the performance of the exercise in cognitive function and ERP analysis, but improved the interaction video game group and aerobic exercise (walking) group over the control group. It was concluded that long-term aerobic exercise like interactive video game is associated with attenuation of cognitive decline in the elderly.

BCP/PCL scaffold의 표면개질을 위한 실리콘, 카르복실기, fibronectin 코팅 및 생체적합성에 관한 연구

  • Gwak, Gyeong-A;Kim, Yeong-Hui;Kim, Min-Seong;Park, Min-Ju;Jyoti, Anirban;Byeon, In-Seon;Lee, Byeong-Taek;Song, Ho-Yeon
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2010.05a
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    • pp.43.1-43.1
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    • 2010
  • 조직공학의 중요한 요소로 작용하는 scaffold는 여러 가지 필수적인 조건들을 만족시켜야 한다. 대표적인 특징들로는 (1)생분해성 및 비독성, (2)넓은 표면적을 갖는 상호 연결된 내부 다공성 구조, (3)구조적 안정성, (4)세포부착 기질의 제공, (5)낮은 면역 반응성, (6)혈전 형성 억제, (7)친수성, (8)생체 기능성 등을 들 수 있다. 이러한 scaffold가 갖추어야 할 특성 중에서 세포 부착 기질 제공을 위하여 scaffold에 표면 개질을 통한 기능기를 도입하였다. 본 연구에서는 BCP scaffold의 구조적 안정성 부여를 위하여 PCL(polycaprolactone)을 infiltration 하였다. PCL은 소수성의 특징을 갖고 있어 세포와 상호작용 할 수 있는 생물학적 반응기가 없기 때문에 세포와의 친화성이 떨어진다. 세포의 친화성을 높여주기 위해 실리콘의 전구체인 TEOS(tetraethly orthosilicate)를 코팅하고, 그 위에 카복실기(carboxylic acid group)를 도입하였다. 또한 세포의 고정화를 높여주기 위해 fibronectin을 코팅하여 BCP/PCL scaffold의 세포 친화성을 높여주었다. 이와 같이 제조된 고기능성 BCP/PCL scaffold의 내부 구조와 특성을 Micro-CT로 확인하였고, 또한 실리콘 코팅 여부를 확인하기 위하여 SEM-EDS를 통해 관찰하였으며, FT-IR 관찰을 통해 카복실기 도입 여부를 확인 하였다. 또한 생체적합성 평가를 위해 MTT assay, 조골세포의 부착에 미치는 영향을 관찰하기 위해 SEM, 조골세포의 유전자 발현에 미치는 영향을 관찰하기 위해 RT-PCR을 통해 확인 하였다.

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Differential effects of the valenced content and the interaction with pacing on information processing while watching video clips (영상물 시청에 발현된 감성 유인가의 차별적 영향과 편집속도와의 상호작용)

  • Lee, Seung-Jo
    • Science of Emotion and Sensibility
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    • v.12 no.1
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    • pp.33-44
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    • 2009
  • This study investigates differential impacts of the positive and negative content and the interaction with pacing, as a structural feature, on information processing while watching televised video clips with moderately intensive emotional tone. College participants watched six positive messages and six negative video clips lasting approximately 60 seconds. Heart rate was used to index attention and skin conductance was used to measure arousal. After all of the stimuli were shown, the participants performed the free recall questionnaire. The result demonstrates, first, positivity superiority on attention in which participants' heart rates were slower during positive content compared to during negative content. Secondly, negativity superiority was shown on free recall memory as participants remembered positive content better than did negative content. The result also manifests the interaction of emotional valence and pacing as the effects of pacing were less for the negatively emotional content compared to those for the positively emotional content. It is suggested that future studies should examine further about the differential and independent functions of positive and negative contents on information processing and the potential interaction with formal features.

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A Music Technology-Based Interactive Music-Making for Improving the Social Communication Skills of Children With Autism Spectrum Disorder (자폐스펙트럼장애 아동의 사회적 의사소통 향상을 위한 음악제작 앱 기반 상호적 음악만들기 사례)

  • Yoon, Sol
    • Journal of Music and Human Behavior
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    • v.18 no.2
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    • pp.19-43
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    • 2021
  • The purpose of this case study was to examine whether an interactive music-making intervention using GarageBand was applicable to improve the social communication skills of school-age children with autism spectrum disorder (ASD). Two children with ASD (both male, ages = 8 and 11 yrs.) participated in this study. The interactive music-making intervention included three stages: 1) musical imitation, 2) musical expression and coordination, and 3) musical interaction. Each session lasted 40 minutes, and sessions took place twice a week over 4 weeks. The participants' social communication behaviors were observed and analyzed in terms of exchanging ideas with each other. Engagement in interactive behaviors (e.g., turn-taking, imitating or reflecting the investigator's music, and creating one's own music using the motive from the investigator) during music making was also analyzed. During the sessions, increases in the attempts to express their opinions on music making processes and requests for help for the process were observed. Engagement in turn-taking form of interactive playing and reflecting the musical motive from a partner (i.e., investigator) were also improved. The Social Responsiveness Scale-2 (SRS-2) ratings indicated negative social behaviors decreased after intervention in both participants. The findings of this study suggest that interactive music-making activities using GarageBand can be an effective method in clinical practice to improve social communication skills for school-aged children with ASD.

Effects of Perceived Interactions of Digital Transformed Services on Intention to Accept Technology (디지털로 전환된 서비스의 지각된 상호작용이 기술수용의도에 미치는 영향)

  • Lee, Dong-Yub;Kim, Gwi-Gon
    • Journal of Digital Convergence
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    • v.19 no.11
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    • pp.287-300
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    • 2021
  • The purpose of this study is to verify the influence relationship of digitally converted services on consumers' intention to use since traditional services are being converted to digital services due to technological development and increase in non-face-to-face services. The study consisted of a program development procedure and a program effectiveness verification procedure, and bootstrapping was performed to verify the mediating effect adjusted along with multiple regression analysis. The subjects of this study were 323 university (graduate) students and the general public residing in Korea. Results. First, it was found that the three perceived interaction factors (perceived communication, perceived control, and perceived reactivity) of digital transformed services had a positive effect on perceived usefulness and perceived ease of use, respectively. Second, the relationship of influence of technology acceptance intention was verified. Third, it was confirmed that the effect of the three perceived interaction factors of digital transformed services on intention to use was mediated by perceived usefulness and perceived ease of use. Fourth, the mediating effect mediated by digital disparity was confirmed. As a result, it was confirmed that the three perceived interaction factors of the digitally converted service are important factors in the intention to use the digitally converted service. This suggests that efforts are needed to minimize the digital divide.