• Title/Summary/Keyword: 반응기준

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Immunocytochemical Study of the Nerve Growth Factor Receptor in the Nucleus Basalis of Meynert of the Growth Receptorn in the Nucleus Basalis of Meynert of the Postnatal Rat BASAL Forebrain (출생후 발생에 따른 흰쥐 전뇌 기저부 Meynert 긴저칙에서의 신경성장인자 수용체에 대한 면역세포화학적 연구)

  • Jeong, Yeong-Hwa;Hong, Yeong-Ho;Sin, Bo-Cheol
    • The Korean Journal of Zoology
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    • v.36 no.4
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    • pp.562-579
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    • 1993
  • 출생후 발생에 따른 흰쥐 전뇌 기저부의 Mevnert 기저핵(nucleus basalis of Mevnert)에서 신경성장인자 수용체(nerve growth factor receptor, NGFr)를 함유하는 신경세포의 면역반응성 및 분포, 세포형의 분류, 각 형별 출현율 및 세포 크기 그리고 세포소기관과 NGFr 면역반응과의 관계를 조사하였다. NGFr 면역반응 신경세포들은 출생후 초기 발생에서 세포질 뿐만 아니라 원형질 막에서도 면역반응을 보였으나, 성체에서는 세포질에서만이 면역반응을 보였다. NGFr 면역반응 신경세포는 형태학적 특징인 세포체의 모양과 장·단축의 비를 기준으로 5가지 형, 즉 1) 원형, 2) 난형, 3) 세장형. 4) 방추형, 5) 삼각형(또는 다각형)세포로 구분되었다 원형과 난형 세포는 출생후 0일에서 각각 15.4%. 50.7%의 높은 출현율을 보였으나, 발생이 진행되면서 점차 감소하여 성체에서 각각 7.8%, 28.6%의 출현율을 보였다 반면, 세장형, 방추형 및 삼각형세포는 출생후 0일에서 각각 22%, 2.6% 9.2%의 낮은 출현율을 보였으나, 발생이 진행되면서 지속적으로 증가하여 성체에서는 각각 29 9%, 5.2%, 28.5%의 높은 출현율을 보였다. 출생후 0일에서 신경세포체의 부피는 매우 작았으나(1,642mm3), 발생에 따라 점차 증가하여 14일, 21일에서는 성체에서보다 매우 컸다(각각 6.745, 6,755mm3) 원형 및 난형세포체의 부피는 21일에서(각각 7 955. 7.020mm3), 세장형 방추형 그리고 삼각형세포체의 부피는 14일에서 제일 컸다(각각 7,067, 6,237, 7,748 mm3) 대체적으로 삼각형세포체의 부피가 제일 컸으며, 방추형세포체의 부피가 제일 작았다. 출생후 순일에서의 전자현미경적 관찰에서 세포소기관중 조면소포체, Golgi체, multivesicular body 그리고 세포표면 원형질막이 강한 NGFr 면역반응을 보였다. 위의 결과들로 미루어 MGFr은 출생후 흰쥐 전뇌 기저부 Meynert 기저핵 신경세포의 분화 및 분포와 밀접한 관계를 갖는 것으로 생각된다.

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Production of Lard Based Biodiesel Using Ultrasound Assisted Trans-Esterification (초음파가 도입된 전이에스테르화 반응을 이용한 돈지원료 바이오디젤의 제조)

  • Cho, Hae-Jin;Lee, Seung-Bum;Lee, Jae-Dong
    • Applied Chemistry for Engineering
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    • v.22 no.2
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    • pp.155-160
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    • 2011
  • An animal fat is an attractive biodiesel energy source for its high stability against oxidation and low incomplete combustion ratio due to the high heating value and cetane value. However, it requires a refinery process because of the high content of saturated acid and impurity which increas the boiling point. In this study, the optimum biodiesel synthetic process of lard is suggested. Indeed, we demonstrate new biodiesel production processes to alter conventional process of heating and mixing by applying ultrasonic energy. While the optimum reaction temperature and mole ratio of methanol and lard, when using conventional mixing and heating process, were $55^{\circ}C$ and 12, respectively, the reaction time were reduced to 30 minutes by applying ultrasonic irradiation power of 500 W. The new process applying ultrasonic irradiation yielded synthetic biodiesel properties as followings: 3.34 cP of the viscosity, 37.0 MJ/kg of the caloric value and below 0.25 mgKOH/g of the acidic value, which satisfy biodiesel quality criteria.

Investigation on Desorption Reaction and Heating Value of Used Activated Carbons Collected from VOC Adsorption Towers (휘발성 유기화합물 흡착탑 폐활성탄의 탈착반응 및 열량특성 연구)

  • Yoon, Sung-Min;Kim, Joo-Yeon;Park, Kun-Yik;Yoon, Soo-Kyung;Kil, In-Sub;Park, Hui-Jae;Rhee, Young-Woo
    • Clean Technology
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    • v.16 no.1
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    • pp.33-38
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    • 2010
  • The characteristics of desorption reaction and the heating values of used activated carbons collected from the companies of Shiwha/Banwal industrial complex were investigated. The desorption characteristics of used activated carbons were analyzed based on the data obtained from a thermogravimetric analyzer. The activation energies and reaction orders for desorption reaction of used activated carbons were calculated by employing Freeman-Carroll method. Heating values of volatile organic compounds(VOC) desorbed from used activated carbons were estimated based on the data obtained from a total hydrocarbon analyzer. It was found that the reaction orders of desorption of used activated carbons were 0.1~0.8, their desorption activation energies, 6.9~26.4 kJ/mol, and VOC heating values, 0.4~10.7 kcal/kg.

Pyrolytic Reaction Pathway of Dichloromethane in Excess Hydrogen (과잉수소 반응분위기에서 Dichloromethane 열분해 반응경로에 관한 연구)

  • Won, Yang-Soo
    • Applied Chemistry for Engineering
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    • v.17 no.6
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    • pp.638-643
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    • 2006
  • Pyrolytic reaction study of dichloromethane ($CH_{2}Cl_{2}$) in excess hydrogen was performed to investigate pyrolytic reaction pathways at a pressure of 1 atm with residence times of 0.3~2.0 sec in the temperature range of $525{\sim}900^{\circ}C$. A constant feed molar ratio $CH_{2}Cl_{2}$:$H_{2}$ of 4:96 was maintained through the experiment. Reagent loss and product formation were monitored by using an on-line gas chromatograph, where batch samples were analyzed by GC/MS. Complete destruction(99%) of the parent reagent was observed at temperature near $780^{\circ}C$ with residence time over 1 sec. Major products observed were $CH_{3}Cl$, $CH_{4}$, $C_{2}H_{4}$, $C_{2}H_{6}$, and HCl. Minor products included $CHClCCl_{2}$, CHClCHCl, $CH_{2}CHCl$, and $C_{2}H_{2}$. The pyrolytic reaction pathways to describe the important features of intermediate product distributions and reagent loss, based upon thermodynamic and kinetic principles, were suggested. The results of this work provided a better understanding of pyrolytic decomposition processes which occur during the pyrolysis of $CH_{2}Cl_{2}$ and similar chlorinated methanes.

Characteristics of Noise Radiated at Dental Clinic (치과병원에서 치료시 발생하는 소음특성)

  • Ji, Dong-Ha;Choi, Mi-Suk
    • Journal of Korean Society of Environmental Engineers
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    • v.31 no.12
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    • pp.1123-1128
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    • 2009
  • Noise radiated from medical treatment at dental clinic will affect the patients. On such point of view, We investigated the noise characteristics in case of medical treatment (scaling, tooth eliminating) and non-medical examination (idling) and also evaluated the degree of indoor noise using the evaluation index such as PSIL, NRN and made up a questionnaire about the reactions to noise. As a result of noise evaluation, it shows that the range of noise level is 67.7~78.3 dB(A) and frequency is very high (above 4 k Hz) and respondents are affected by noise (unpleasantness, hesitation to visit dental clinic, shivering with noise, being astonishment). Analysis by PSIL showed that it was no problem to conversation between worker and patient. But it exceeded the noise permit level in working space by NR-curve. To relieve a fear of noise in patients, they are considered to offer the ear protection, choose the low noisevibration equipment and use the masking effect. They are of great advantage to dental clinics to i prove dental service and competitiveness.

Rating Floor Impact Noise in Apartment Buildings Through Subjective Evaluation Tests (청감실험에 의한 공동주택 바닥충격음의 평가등급 설정)

  • 전진용;류종관
    • The Journal of the Acoustical Society of Korea
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    • v.22 no.2
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    • pp.88-95
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    • 2003
  • The auditory experiments based on subjective responses were undertaken for the standard heavy and light weight impact noise and rubber ball impact noise, jumping noise to investigate relations between floor Impact noise levels and subjective responses and to establish the upper/lower limits of floor impact noises. As a result, it was shown that relations between floor Impact noise levels and subjective responses was linear and the lower limit of heavy-weight impact noise was L/sub i, Fmax, AW/=46㏈ and the lower limit of light-weight impact noise was L'/sub n,AW/=56㏈. Finally the 3 subjective classes of floor impact noises were established.

Estimating Geotechnical System Response Probability of Internal Erosion Risk in Fill Dam using Event Tree Analysis (사건수 분석 기법을 이용한 필댐의 내부 침식 위험도에 대한 지반공학적 시스템 응답 확률 산정)

  • Noh, Kyung-Lyun;Lim, Jeong-Yeul;Mok, Young-Jin;Jung, Young-Hoon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.34 no.6
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    • pp.1815-1829
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    • 2014
  • Recently frequent collapse of old fill dams has taken place, which increases social awareness in the safety of the infrastructure. Fill dams in Korea has been incautiously regarded as safe once the fill dam is considered to have a full capacity to retain a conservative design flood determined by government authorities. However, developed foreign countries has been managing their fill dams by introducing systematic risk assessment techniques over a long period of time. In this study, the system response probabilities of the deteriorated old fill dams in Korea were systematically evaluated and analyzed by using the internal erosion toolbox based on the event tree analysis technique. The probability of the existence of flaw and the magnitude of the hydraulic gradient through a potential crack can significantly influence the geotechnical system response probability. The results of this study show that the probability of the existence of flaw and the magnitude of the hydraulic gradient through a potential crack can significantly influence the geotechnical system response probability and the risk of the deteriorated fill dam can be quantitatively assessed.

The Study of Optimal Conditions for Synthesis and Purification of 1, 2-Octanediol Galactoside (1, 2-Octanediol Galactoside 합성을 위한 최적 조건 및 정제 연구)

  • Jung, Kyung-Hwan
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.1
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    • pp.1-9
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    • 2022
  • 1, 2-Octanediol (OD) as a cosmetic additive has been used simultaneously as a preservative and humectant. To solve the skin problem by 1, 2-octanediol (OD), we have synthesized 1, 2-octanediol galactoside (OD-gal) using Escherichia coli β-galactosidase (β-gal). Meanwhile, the optimal amount of β-gal, OD concentration, pH, and temperature for OD-gal synthesis were 4.5 U/ml, 150 mM, 7.0, and 37℃, respectively. Under these conditions, 150 mM OD was converted into about 55.9 mM OD-gal during 24 hours, in which the conversion yield (mole basis) was about 37.2%. In addition, OD-gal of 67.4 mg could be purified from a 9 ml reaction mixture, in which the overall synthesis yield from OD to the purified OD-gal was about 34.1% (weight basis) and 16.2% (mole basis), respectively. We are expecting that these results will be helpful to develop a safer additive in the cosmetic industry as basic data.

Kinetics of the Reaction of Benzyl Chlorides with Pyridine in Methanol Solvent under High Pressure (고압하의 메탄올 용매내에서 염화벤질류와 피리딘과의 반응에 대한 반응속도론적 연구)

  • Oh Cheun Kwon;Young Cheul Kim;Jin Burm Kyong;Kee Joon Choi
    • Journal of the Korean Chemical Society
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    • v.31 no.5
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    • pp.413-418
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    • 1987
  • Rates of the reaction for p-nitro benzyl chloride, benzyl chloride and p-methyl benzyl chloride with pyridine in methanol solvent have been measured by an electric conductivity method at 40$^{\circ}$C and 50$^{\circ}$C under various pressures (1∼2000bar). Pseudo first-order rate constants and second-order rate constants were determined. Rates of these reactions were increased in the order p-NO$_2$ < p-H < p-CH$_3$ and increased with temperature, pressure and concentration of pyridine. From those rate constants, the activation parameters were evaluated. The activation volume and the activation compressibility coefficient are both negative values, but the activation enthalpy is positive and the activation entropy is large negative value. From the evaluation of the ground state and transition state which was resulted from substituents and pressure, it was found that this reaction proceeds through S$_N$2 reaction, and S$_N$2 fashion is slightly disappeared as pressure increases.

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Robust Extrapolation Design Criteria under the Uncertainty of Model and Error Structure (모형과 오차구조의 불확실성하에서의 강건 외삽 실험설계)

  • Jang, Dae-Heung;Kim, Youngil
    • The Korean Journal of Applied Statistics
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    • v.28 no.3
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    • pp.561-571
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    • 2015
  • When we consider an optimal design to predict the response corresponding to the point outside the design region, we are extremely careful about choosing the design criteria for selecting the support points. The assumed model and its accompanying error structure should be assumed to extend beyond the design region for the selected design criteria to be valid. Thus, we modify the existing design criteria such as extrapolation-optimality to be suited to those situations. We propose some maximin approaches in this paper. Simple and quadratic regression models are tested to find the basic characteristics of such maximin approaches. Some main findings are discussed in the conclusion.