• Title/Summary/Keyword: 반응경로

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Properties of the Arterial Pressor Response Induced by Stimulation of the Ventral Root Afferent Fibers in the Cat (고양이 척수 전근내 감각신경 자극으로 유발된 승압반응의 생리학적 특성)

  • Kim, Jun;Seoh, Sang-Ah;Sung, Ho-Kyung
    • The Korean Journal of Physiology
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    • v.23 no.1
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    • pp.129-138
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    • 1989
  • In an attempt to characterize the ventral root afferent fibers, arterial blood pressure responses to stimulation of the ventral root (VR) were observed in anesthetized cats. Effects of the morphine administered either intravenously or direct spinally and of the spinal lesions on the pressor responses were compared. Followings are the results obtained. 1) Stimulation of the VR with C-strength, high frequency stimuli evoked a marked pressor response. No depressor response, which had been reported during peripheral nerve stimulation, was observed during VR stimulation with low frequency. 2) Acute cervical spinalization abolished the pressor response, indicating the involvement of supraspinal mechanism. 3) The ascending spinal pathways of the pressor response were located in the dorsolateral funiculus bilaterally. 4) Intravenously administered morphine exaggerated the pressor response to VR stimulation, while direct spinally administered morphine suppressed it. From the above results it was concluded that the ventral root afferent fibers have more similar properties to muscular C-afferent fibers than to cutaneous C-fibers.

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Oxidation of 2,6-Dimethylnaphthalene by Co-Mn-Br Based Homogeneous Catalyst (Co-Mn-Br계 균일촉매를 이용한 2,6-Dimethylnaphthalene의 산화반응)

  • Kim, Dong-Bum;Park, Seungdoo;Cha, Woonou;Roh, Hang-Duk;Kwak, Kyu Dae
    • Applied Chemistry for Engineering
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    • v.10 no.6
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    • pp.863-870
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    • 1999
  • The catalytic performance of Co-Mn-Br system was performed in the 2,6-dimethylnaphthalene(DMN) oxidation at relatively mild reaction conditions such as $160^{\circ}C$ and $6kg/cm^2$. Experiments were conducted using a $2{\ell}$ batch reactor with varying the concentrations of catalysts. The reaction route of DMN oxidation was considered by measuring the concentration of intermediate species. As the intermediate species, 2-formyl-6-naphthoic acid, 2-methyl-6-naphthoic acid and 2-hydroxymethyl-6-methylnaphthalene are found. It was found that the yield of 2,6-naphthalene dicarboxylic acid(NDA) is largely dependent on the Co and Br concentrations. In addition, it was observed that color-b was closely related with Mn concentration in this experimental range. The burning loss of solvent could be reduced by controlling the concentration of Mn and Br. Addition of small amount of Ce and Cu compounds led to increase the NDA yields and decrease the burning amount of solvent.

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Effect of We-ness and Flow on the Spectator Promotion of K-League (우리의식과 플로우가 K-리그 관람촉진에 미치는 영향)

  • Yoon, Jong-Hyun;Han, Se-Hee;Kim, Dong-Tae
    • The Journal of the Korea Contents Association
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    • v.14 no.1
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    • pp.435-443
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    • 2014
  • The aim of this study was to look for the cause of shortage of K-League spectators from a consumer's perspective and to offer solutions. For this, we offered enhancement method of the K-League spectators through dual path model based on existing relative researches. The first path involved consumer reaction to external factors of the K-League game. This path explained relational view(=we-ness) of consumers on K-League game(Hypothesis 1, 2). The second path explained personal view on K-League game. This path means consumer reaction to K-League game itself(Hypothesis 3, 4). The empirical study was based on a field survey and structural equation model. The results showed that we-ness positively affected team loyalty(Hypothesis 1) and the team loyalty positively affected spectating intentions(Hypothesis 2). It also revealed that flow of K-League game positively affected consumer satisfaction(Hypothesis 3). Finally consumer satisfaction was found to affect spectating intentions(Hypothesis 4). The significance of present study is to extend scope of research which is related with cheerleading of sports game. And this study emphasize the importance of we-ness and flow in sports game.

Single-molecule Alkylation of Isoparaffin Using Peroxide Initiator for Making Synthetic Lubricant (합성 윤활유 제조를 위한 퍼옥사이드계 개시제를 이용한 이소파라핀의 단독 알킬레이션)

  • Khadka, Roshan;Lee, Sang-Woo;Kim, Yong-Woon;Ryu, Jae-Wook;Yim, Jin-Heong
    • Polymer(Korea)
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    • v.38 no.4
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    • pp.496-501
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    • 2014
  • Polyalphaolefin (PAO) is a synthetic lubricant that is superior to mineral-based lubricants in terms of physical and chemical characteristics such as low pour point (PP), and high viscosity index (VI). This paper first reports a novel preparation route for a synthetic lubricant via alkylation of isoparaffins using a peroxide initiator without olefin. Alkylation of three kinds of isoparaffins such as i-$C_{16}$, i-$C_{18}$, and i-$C_{23}$ as well as alkylation of i-$C_{18}$ with 2-pentene using di-tert butyl peroxide initiator were conducted under various conditions to confirm alkylation reaction from isoparaffins themselves i.e; Single-molecule alkylation. Various properties of each alkylates (VI and PP) were investigated as a synthetic lubricant. Single-molecule alkylation made from i-$C_{16}$ a,nd i-$C_{18}$ showed ultra high VI (>140) and low PP (< $-30^{\circ}C$).

Endoplasmic Reticulum Signaling for Recombinant-protein Production (재조합 단백질 생산을 위한 소포체 신호전달)

  • Goo, Tae-Won;Yun, Eun-Young;Kang, Seok-Woo;Kwon, Ki-Sang;Kwon, O-Yu
    • Journal of Life Science
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    • v.17 no.6 s.86
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    • pp.847-858
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    • 2007
  • The endoplasmic reticulum (ER) is an important intracellular organelle for folding and maturation of newly synthesized transmembrane and secretory proteins. The ER provides stringent quality control systems to ensure that only correctly folded proteins exit the ER and unfolded or misfolded proteins are retained and ultimately degraded. The ER has evolved stress response both signaling pathways the unfolded protein response (UPR) to cope with the accmulation of unfolded or misfolded proteins and ER overload response (EOR). Accumulating evidence suggests that, in addition to responsibility for protein processing, ER is also an important signaling compartment and a sensor of cellular stress. In this respect, production of bio-functional recombinant-proteins requires efficient functioning of the ER secretory pathway in host cells. This review briefly summarizes our understanding of the ER signaling developed in the recent years to help of the secretion capacities of recombinant cells.

A Study on Macroeconomic Linkages between the USA and Japan (미일간 거시경제적 연계성에 대한 연구)

  • Lee, Jai Ki
    • International Area Studies Review
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    • v.15 no.3
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    • pp.175-188
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    • 2011
  • This study aims to examine how the U.S. economic shocks affect the Japanese economy. It is widely believed that the U.S. economy has a significant effect on the Japanese economy. Actually, the U.S. accounts for a considerable amount of Japan's exports and imports. To the economic policymakers, it is very important to know how economic disturbances generated by the U.S. are transmitted to the Japanese economy. A vector autoregression(VAR) model is employed to investigate the international transmission channel of economic disturbances. The interactions of the U.S.-Japansese economy are investigated by using variance decompositions(VDCs). The results of this study provided the evidence that the U.S. economic shocks were important for the Japanese economy during the sample period. This study supports the notion of economic dependence of smaller open economy such as Japan as compared with larger economy such as the U.S.

Design of VMS Fuzzy Feedback Controller for VMS Routing Information (대안경로 안내용 VMS 퍼지 피드백 제어기법)

  • Park, Eun-Mi;O, Hyeon-Seon;Yang, Tae-Gyu
    • Journal of Korean Society of Transportation
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    • v.29 no.6
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    • pp.129-136
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    • 2011
  • Variable Message Signs have been used for providing information on the current traffic conditions. However, it is considered more important to achieve optimal traffic allocation among the alternative routes by strategic VMS information provision. Fuzzy control is very effective and efficient to deal with such systems that are too complex and uncertain to build mathematical models. In this paper, a fuzzy feedback controller for VMS is proposed, whose goal is to achieve the travel time equilibrium between the two alternative routes. The performance of the suggested controller is implemented and examined using MATLAB/Simulink. More robust controller applicable to a real highway network is suggested for the further research.

Analysis of Ocean Color Data for Observation on the Ocean Environment Change Caused by Typhoon Path (태풍의 이동경로에 따른 해양환경변화관측을 위한 해색 자료 분석)

  • Jeong, Jong-Chul
    • Journal of the Korean Association of Geographic Information Studies
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    • v.16 no.1
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    • pp.59-66
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    • 2013
  • When the typhoons are passing over the ocean, the ocean environment has both physical and biological impacts on the East, South sea and Yellow sea of Korea. As a result of typhoon path, vertical mixing and upwelling injured colder subsurface water, and leaded to phytoplankton blooming along the typhoons. The ocean environment before and after a typhoon played an important role in the biological effect of sea surface. Although the magnitude of sea surface temperature (SST) gets cooler because of typhoon path, other physical and biophysical responses are quite different such as chlorophyll, K490 and SST. The purpose of this study is to compare with the typhoon path that influenced the Korean Peninsula and ocean environment parameters which were observed by ocean color remotely-sensed data. The MODIS data were used to assess the parameters of ocean environments such as K490 and chlorophyll data from 2002 to 2005. Mean chlorophyll from MODIS data increased by about 1-4% in the East sea after the typhoon. Mean concentration of MODIS chlorophyll in the post-typhoon period increased along the typhoon passage. However, Jeju coastal area has different patterns from those of the East sea.

국가간 기술혁신 파급경로에 관한 실증분석

  • 정동진;김한주;김상태;조상섭
    • Proceedings of the Korea Technology Innovation Society Conference
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    • 2004.11a
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    • pp.101-113
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    • 2004
  • 본 연구는 기술혁신파급경로를 결정하는 국가 간 무역역할에 대한 실증적인 분석을 목적으로 한다 이 연구목적을 위하여, 최근 자료인 1980년부터 2003년까지 15개 OECD국가를 대상으로 자국의 기술혁신을 결정하는 중요한 변수로 알려진 자국 R&D축적 및 무역대상국의 R&D축적자료를 구축하였으며, 이를 무역지수인 쌍방간에 수출 및 수입량을 경제규모로 나눈 가중지수를 이용하여 유입된 R&D축적량을 구축하였다. 또한 대상변수들의 기술혁신파급역할에 대하여 최근 논의되고 있는 비정상적 패널기법을 이용하여 분석하였다. 최근 제안되고 있는 비정상적 패널기법을 이용하여 국제 간에 기술혁신파급경로를 분석한 결과를 간단하게 요약하면, 다음과 같다. 첫째, 분석대상변수들은 비정상성을 갖는 것으로 나타났다. 둘째, 그러나 장기적으로 분석대상변수들이 서로 균형상태를 나타내는 공적분관계에 있음을 알 수 있었다. 셋째, 국가 간에 기술혁신파급경로의 방향과 정도를 파악하기 위하여 패널 공적분계수를 추정하였으나, 설정함수형태에 따라서 여러 가지 상반된 실증결과가 나타났다. 따라서 기존 연구Coe et al., 1995, Keller, 1998, Kao, et al., 1999 그리고 Funk, 2001]의 분석결과 및 그 시사점들이 서로 다른 이유는 분석대상변수들의 선택차이뿐만 아니라, 기술혁신경로에 대한 설정함수형태에 따라서 서로 다른 분석결과가 나타날 수 있는 가능성을 보여준다. 본 연구에서 나타난 분석결과의 시사점을 보면, 국가 간에 기술혁신파급경로분석은 기술혁신파급을 결정하는 매개변수선정도 중요하지만, 결정된 설명변수들 사이에 어떤 기술혁신파급에 관한 연관관계가 존재하는지에 대한 실증분석 즉 파급경로분석도 매우 중요함을 보여준다. 이러한 파급경로분석에는 기존의 선형가정뿐만 아니라 비선형가정을 이용한 기술파급경로분석을 통한 시사점제안이 요구된다.관적인 시스템을 제공하는 것이다.가 생성된다. $M_{C}$에 CaC $l_2$를 첨가한 경우 $M_{C}$는 완전히 $M_{Cl}$ 로 전이를 하였다. $M_{Cl}$ 에 CaC $l_2$를 첨가하였을 경우에는 아무런 수화물의 변화는 발생하지 않았다. 따라서 CaS $O_4$.2$H_2O$를 CaC $O_3$및 CaC $l_2$와 반응시켰을 때의 AFm상의 안정성 순서는 $M_{S}$ < $M_{C}$< $M_{Cl}$ 로 된다.phy. Finally, Regional Development and Regional Environmental Problems were highly correlated with accommodators.젼 공정을 거쳐 제조된다는 점을 고려할 때 이용가능한 에너지 함량계산에 직접 활용될 수는 없을 것이다.총단백질 및 AST에서 시간경과에 따른 삼투압 조절 능력에 문제가 있는 것으로 보여진다.c}C$에서 5시간 가열조리 후 잔존율은 각각 84.7% 및 73.3%였고, 질소가스 통기하에서는 잔존율이 88.9% 및 81.8%로 더욱 안정하였다.8% 및 12.44%, 201일 이상의 경우 13.17% 및 11.30%로 201일 이상의 유기의 경우에만 대조구와 삭제 구간에 유의적인(p<0.05) 차이를 나타내었다.는 담수(淡水)에서 10%o의 해수(海水)로 이주된지 14일(日) 이후에 신장(腎臟)에서 수축된 것으로 나타났다. 30%o의 해수(海水)에 적응(適應)된 틸라피아의 평균 신사구체(腎絲球體)의 면적은 담수(淡水)에 적응된 개체의 면적보다 유의성

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Reconstruction of Metabolic Pathway for the Chicken Genome (닭 특이 대사 경로 재확립)

  • Kim, Woon-Su;Lee, Se-Young;Park, Hye-Sun;Baik, Woon-Kee;Lee, Jun-Heon;Seo, Seong-Won
    • Korean Journal of Poultry Science
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    • v.37 no.3
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    • pp.275-282
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    • 2010
  • Chicken is an important livestock as a valuable biomedical model as well as food for human, and there is a strong rationale for improving our understanding on metabolism and physiology of this organism. The first draft of chicken genome assembly was released in 2004, which enables elaboration on the linkage between genetic and metabolic traits of chicken. The objectives of this study were thus to reconstruct metabolic pathway of the chicken genome and to construct a chicken specific pathway genome database (PGDB). We developed a comprehensive genome database for chicken by integrating all the known annotations for chicken genes and proteins using a pipeline written in Perl. Based on the comprehensive genome annotations, metabolic pathways of the chicken genome were reconstructed using the PathoLogic algorithm in Pathway Tools software. We identified a total of 212 metabolic pathways, 2,709 enzymes, 71 transporters, 1,698 enzymatic reactions, 8 transport reactions, and 1,360 compounds in the current chicken genome build, Gallus_gallus-2.1. Comparative metabolic analysis with the human, mouse and cattle genomes revealed that core metabolic pathways are highly conserved in the chicken genome. It was indicated the quality of assembly and annotations of the chicken genome need to be improved and more researches are required for improving our understanding on function of genes and metabolic pathways of avian species. We conclude that the chicken PGDB is useful for studies on avian and chicken metabolism and provides a platform for comparative genomic and metabolic analysis of animal biology and biomedicine.