• Journal of Korean Academy of Nursing
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• v.25 no.3
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• pp.597-607
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• 1995

1960년대 이후 인공호흡기(mechanical ventilator)의 보급과 최근 의료과학의 발달, 간호의 질적 향상의 결과로 저체중출생아를 포함한 고위험 신생아의 생존율이 높아져왔다. 호흡장애증후군(RDS)은 일차적으로 폐포의 완전한 확장을 위해 필요한 계면활성물질(surfactant)의 부족, 미발달된 심폐기능에 의한 병리적 현상으로 저체중아의 가장 큰 원인이 되어왔다. RDS로 인해 인공호흡기에 의존해 있는 저체중아의 경우 적절한 산소공급과 이를 위한 호흡의 유지는 치료의 가장 큰 핵심이 되며, 이를 위한 기관내 흑은 비인두 흡인 (nasopharyngeal suction)은 신생아 중환자실(NICU)의 가장 중요한 간호행위가 되어왔다. 인공호흡기를 위한 기관삽관은 그 자체가 기도의 성모운동을 방해하고 기침반사를 억제시켜 폐 분비물의 효과적 배출을 억제하며, 특히 저체중아의 경우 조산과 관련하여 미발달된 흥곽운등과 심폐기능은 폐분비물의 이동을 저해하는 요소이다. 따라서 기도내의 분비물의 이동을 효과적으로 하여 흡인 시에 최대한의 효과를 돕기 위해 흥곽 물리요법(chest physiotheraphy : CPT)의 한 형태인 흉곽진동법 (Chest Vibration : CV)가 행해져 왔다. 그러나 저체중아를 위한CV의 임상적 적용은 그 대상의 생리적 특성, CV의 적용부위(site)와 기간(duration)에 대한 과학적 근거 없이 만성감염이나 폐질환을 가진 성인이나 cystic fibrosis환자를 위한 CV protocol을 무분별하게 채택하여 저체중아에게 행하여져 왔다 이에 본 연구자는 저체중아에 대한 CV의 안전성을 평가하고, 이에 기초하여 저체중아에게 바람직한CV의 형태를 알아보고자 본 연구를 시작하였다. 연구설계는 CV의 안전성을 평가하기 위한 실험연구이다. CV의 안전성은 RDS치료의 가장 일차적 목표인 oxygenation변화에 의해 평가될 수 있으므로, 본 실험 연구에서는 Pulse oximeter에 의해 계속적으로 측정된 산소포화 변화(oxygen saturation change)를 측정하였다. 실험대상은 미국동부에 위치한 대학병원의 NICU에 입원하여 RDS와 관련된 호흡장애로 인공호흡기에 의존해 있는 10명의 저체중아였다. 인공호흡기에 의존된 모든 저체중아는 Pulse oximeter와 심폐기능 측정기(cardiopulmonary monitor)에 의해 산소공급과 호흡상태가 계속 측정되고 있었다. 실험대상의 평균 출생시 몸무게는 평균 1,3050gm(SD=580.6)이었고, 임신월령 은 평균 28.6주(SD=3.1)였다. RDS가 그들의 일차적 진단명이었고, 그중 4명은 pneumonia, atelectasis의 합병증을 가지고 있었다. 10명중 6명은 intermittent mandatory ventilation(IMV)의 형태로, 4명은 continuous positive airway pressure(CPAP)의 형태로 인공호흡기에 의존되어 있었고 CV시의 FiO2는 평균 42.3(SD=21.2)였다. CV는 중환아용 소형진동기 (minivibrator)를 이용해 가각 10명 의 간호사에 의해 행하여 졌고, 최소 22초에서 최대 100초 동안 실시되었다. 50%의 간호사는 30초에서 40초간 CV를 실시하였으며, CV의 적용부위도, 전후 흉곽부위, 혹은 병변이 있는 좌 우측, 흑은 양쪽 흉벽 등으로 다양했고, 적용방법도 원형으로 돌려가며(circular motion), 혹은 아래에서 위로, 혹은 아무런 기준없이 간호사의 기호에 따라 다양하게 적용되었다. 산소포화의 변화는 CV가 행해지기 전.후로 5초동안 관찰되었다. 연구의 결과, 산소포화 변화는 비 모수통계(non parametric statistics)의 일종인 Matched Paired Wilcoxon test로 분석 한 결과 CV후에 3%의 감소를 보였다(P<.05). 저체중아에 있어 산소포화의 3%감소는 임상적으로 중요한 의미가 없다고 사료되어지며, 실제 흡인전의 과도호흡에 의해 CV를 행하기 이전의 산소공급수준으로 돌아 왔다. CV실시 기간과 산소포화와의 상관관계는 비 모수통계인 Spearman rho correlation coefficient를 이용하여 분석하였는데, 이 두 변수는 서로 관계가 없는 것으로 나타났다(P>.05) 또한 CV와 흡인 후에 각각의 간호사들에게 CV를 필요로 한 저체중아의 기준, 적용부위, 기간, 방법등에 대한 기준을 물었으나 대상의 특성에 따른 간호사정에 의존하기보다는 간호사 각자의 선호하는 방법이나 습관에 라 행하는 것으로 나타났다. 결론적으로 CV와 산소포화 변화와의 관계, NICU에서 관찰된 CV의 임상적 적용을 기초로 저체중아에게 안전한 CV protocol은 신생아용 소형 진동기를 이용하여, 양쪽 흉곽의 늑골하측 변연 부위(low lateral costal margin)에서 시작하여 흉골 중앙부위 방향으로 30초 동안 진동기를 적용하는 것이 좋은 것으로 나타났다. 이에 CV의 효과를 평가하기 위한 보다 과학적인 접근방법으로, CV와 흡인의 결과인 가래(sputum)에 대한 연구를 제언하는 바이다.

• Analytical Science and Technology
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• v.25 no.2
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• pp.121-126
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• 2012

It is essential to evaluate the quality of Hanji record paper without damaging the record paper by previous destructive methods. The samples were Hanji record paper produced in the 1900s. Near-infrared (NIR) spectrometer was used as a non destructive method for evaluating the quality of record papers. Fourier transform (FT) spectrometer was used with 12,500 to 4,000 $cm^{-1}$ wavenumber range for quantitative analysis and it has high accuracy and good signal-to-noise ratio. The acidity and moisture content of Hanji record paper were measured by integrating sphere as diffuse reflectance type. The acidity (pH) of chemical factors as a quality evaluated factor of Hanji was correlated to NIR spectrum. The NIR spectrum was pretreated to obtain the coefficients of optimum correlation. Multiplicative scatter correction (MSC) and First derivative of Savitzky-Golay were used as pretreated methods. The coefficients of optimum correlation were calculated by PLSR (partial least square regression). The correlation coefficients ($R^2$) of acidity had 0.92 on NIR spectra without pretreatment. Also the standard error of prediction (SEP) of pH was 0.24. And then the NIR spectra with pretreatment would have better correlation coefficient ($R^2$ = 0.98) and 0.19 as SEP on pH. For moisture contents, the linearity correlation without pretreatment was higher than the case with pretreatment (MSC, $1^{st}$ derivative). As the best result, the $R^2$ was 0.99 and SEP was 0.45. This indicates that it is highly proper to evaluate the quality of Hanji record papers speedily with integrated sphere and FT NIR analyzer as a non-destructive method.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.23 no.3
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• pp.300-305
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• 2012

In this paper, a miniaturized bow-tie monopole UWB antenna with band rejection characteristic is proposed. To miniaturize the proposed antenna, a perfect magnetic wall(PMW) condition is applied to primitive bow-tie monopole antenna. An uneven ground patch, a tapered feeding structure and a edge-chopped main patch are adapted for impedance matching. A quater-lambda slot resonator is inserted at main patch to prevent interference in UWB band from another band. The proposed antenna is fabricated on Taconic RF60-A substrate with relative permittivity of 6.15. The size of the proposed antenna is $30.0{\times}39.7mm^2$, which is only 45 % of the conventional bow-tie monopole antenna. The proposed antenna covers full UWB band with return losses less than -10 dB and has band stop characteristic in 5 GHz WLAN band. The maximum gains are within -1.0~5.0 dBi, the group delay variations are within 1.0 ns and the radiation patterns show directivity characteristics in x-y plane.

• Journal of the Korean Geotechnical Society
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• v.36 no.11
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• pp.157-165
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• 2020

At present, there are no clearly stated criteria or theories in calculating additional vertical dynamic loads that occur at the machine foundation due to vibration and reflecting them in the design at home and abroad. According to the domestic standard, although it is not a serious vibration condition, the additional dynamic load due to vibration is considered up to 100% of the static load. This is an extremely conservative design. The purpose of this study is to propose a model test method for evaluating the quantitative magnitude of additional dynamic loads that are generated at certain static loads due to vertical mechanical vibrations. As preliminary basic tests for the model tests, the test for evaluating the effects of reflective wave that may occur within a limited size soil box and the test for estimating the natural frequency of the devised model soil-foundation system were carried out. From the analysis of results for basic tests, a method to minimize the influence of the reflected wave was prepared, and the effect of the resonance of the model system was minimized during the model tests. After the basic tests, the main model tests were conducted. Through the proposed main test, the quantitative magnitude of additional dynamic loads caused by machine vibration on a shallow foundation for machine on medium dense sand foundations were evaluated. From the results of the model test, the feasibility of design applied at home and abroad was reviewed.

• Journal of the Microelectronics and Packaging Society
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• v.24 no.3
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• pp.71-76
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• 2017

The electrical behavior and flexibility of the screen printed Ag circuits were investigated with infrared radiation sintering times and sintering temperatures. Electrical resistivity and radio frequency characteristics were evaluated by using the 4 point probe measurement and the network analyzer by using cascade's probe system, respectively. Electrical resistivity and radio frequency characteristics means that the direct current resistance and signal transmission properties of the printed Ag circuit. Flexibility of the screen printed Ag circuit was evaluated by measuring of electrical behavior during IPC sliding test. Failure mode of the Ag printed circuits was observed by using field emission scanning electron microscope and optical microscope. Electrical resistivity of the Ag circuits screen printed on Pl substrate was rapidly decreased with increasing sintering temperature and durations. The lowest electrical resistivity of Ag printed circuit was up to $3.8{\mu}{\Omega}{\cdot}cm$ at $250^{\circ}C$ for 45 min. The crack length arisen within the printed Ag circuit after $10{\times}10^4$ sliding numbers was 10 times longer than that of after $2.5{\times}10^4$ sliding numbers. Measured insertion loss and calculated insertion loss were in good agreements each other. Insertion loss of the printed Ag circuit was increased with increasing the number of sliding cycle.

• Journal of Life Science
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• v.23 no.6
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• pp.804-811
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• 2013

Melanopsin is an opsin-like photopigment found in the small proportion of photosensitive ganglion cells of the retina. It is involved in the regulation of the synchronization of the circadian cycle as well as in the control of pupillary light reflex. The purpose of the present study is to investigate whether melanopsin is also expressed in the other areas of the central visual system outside the retina. We have studied the distribution and morphology of neurons containing melanopsin in the mouse visual cortex with antibody immunocytochemistry. Melanopsin immunoreactivity was mostly present in neuronal soma, but not in nuclei. We found that melanopsin was present in a large subset of neurons within the adult mouse visual cortex with the highest density in layer II/III. In layer I of the visual cortex, melanopsin-immunoreactive (IR) neurons were rarely encountered. In the mouse visual cortex, the majority of the melanopsin-IR neurons consisted of round/oval cells, but was varied in morphology. Vertical fusiform and pyramidal cells were also rarely labeled with the anti-melanopsin antibody. The labeled cells did not show any distinctive distributional pattern. Some melanopsin-IR neurons in mouse visual cortex co-localized with nitricoxide synthase, calbindin and parvalbumin. Our data indicate that melanopsin is located in specific neurons and surprisingly widespread in visual cortex. This finding raises the need of the functional study of melanopsin in central visual areas outside the retina.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.3
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• pp.233-240
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• 2018

Radar cross section (RCS) analysis of chaff clouds is essential for the accurate detection and tracking of missile targets using radar. For this purpose, we compare the performance of two existing methods of predicting RCS of chaff clouds. One method involves summing up the RCS values of individual chaffs in a cloud, while the other method predicts the RCS values using aerodynamic models based on the probability density function. In order to compare and analyze the two techniques more precisely, the RCS of a single chaff computer-aided design model consisting of a half wavelength dipole was calculated using the commercial electromagnetic numerical analysis software, FEKO 7.0, to estimate the RCS values of chaff clouds via simulation. Thus, we verified that our method using the probability density distribution model is capable of analyzing the RCS of chaff clouds more efficiently.

• The Journal of Korean Academy of Sensory Integration
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• v.16 no.1
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• pp.14-24
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• 2018

Objective : The purpose of this study was to identify the effect of Interactive Metronome (IM) training on postural control and hand writing performance of children with Attention Deficit Hyperactivity Disorder (ADHD). Methods : Participant was a third grade elementary school student diagnosed with ADHD. ABA design was used and a total of 30 sessions were held for 3 sessions every week for a total of 10 weeks. In the intervention period, IM training was conducted for 40~50 minutes before intervention for writing, and the writing task was carried out. We evaluated the handwriting legibility and speed. Before baseline A and within a month after A' phase, Clinical Observation of Motor and Postural Skills (COMPS) was evaluated to examine the changes in postural control of the student. Results : After the IM intervention, the postural control of the student improved in the score of slow movement, finger-nose touching, and asymmetrical tonic neck reflex. The handwriting legibility and speed has also tended to increase during the intervention period, but it has not significantly changed. Conclusion : This study could be used as an evidence that the IM training aimed at postural control and handwriting ability could enhance the ability to improve postural control and thereby provide fundamental knowledge for future studies.

• Journal of the Korean Chemical Society
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• v.51 no.4
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• pp.318-323
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• 2007

Electronic photofragmentation spectrum of protonated tyrosine-alanine dipeptide ions(YAH+) was obtained in the wavenumber region of 34500~36700 cm-1 using a quadrupole ion trap time-of-flight mass spectrometer (QIT-TOFMS). YAH+ ions were produced by electrospray ionization, stored in the ion trap and then irradiated by ultraviolet laser pulses which induced photofragmentation of the ions. The electronic photofragmentation spectrum was obtained by monitoring the photodissociation yields of YAH+ ions as a function of the laser wavelength. The spectrum exhibited two broad peaks which were assigned as S1 and S2 by theoretical calculations using a time-dependent density functional method. The broad widths of the peaks in the spectrum were explained by the overlaps of the peaks originated from various conformers of YAH+ ions which were present in the gas phase at room temperature and also by the contributions of the hot bands.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2009.06a
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• pp.208-208
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• 2009

최근 광섬유 센서기술의 수요는 전 산업분야에 걸쳐 높아지고 있으며, 이에 비례하여 기업 간, 국가 간 경쟁이 첨예화되고 있다. 또한 소형화, 경량화, 고성능화 센서에 대한 요구도 높아지고 있어 종래의 각종 센서들의 형태와 개선을 위한 연구개발이 매우 활발하게 전개되고 있으므로 이를 대체할 수 있는 광섬유 센서의 수요가 급격히 늘어날 전망이다. 기존 침입자 감지 시스템은 태풍, 낙뢰, 폭설, 폭우 등의 기상변화나 지반 흔들림, 통행차량 진동 및 전자기 간섭 등에 영향을 받아 오작동, 오경보가 빈번히 발생된다. 이러한 문제의 해결책으로 광섬유 센서 케이블을 이용한 시스템이 대안으로 부각되고 있다. 현재 국내에서 군부대, 공항을 중심으로 펜스와 휴전선 철책에 힘입자 감지를 위하여 도입되고 있다. 광섬유 센서 케이블을 사용하는 광망경비시스템은 광섬유 센서 케이블을 그물망 형태(광망)로 만들어 경계 지역에 설치된다. 광망경비시스템의 원리는 광섬유에 광펄스를 입사시켜 순환시키는데 침입자가 광망을 절단하거나 외력을 가할 경우 발생되는 레일리 산란에 기인하는 후방산란과 접속점과 파단점에서 생기는 반사광을 OTDR(Optical Time Domain Reflectometer)로 검출하여 침입상황 및 침입위치를 탐지한다. 그러나 이러한 침입자 감지를 위한 광망경비시스템의 핵심부품인 광섬유 센서 케이블은 기존에 전량 해외수입에 의존하고 있는 실정이며, 지금까지 국내에서 생산하기 위한 제작 기술과 노하우가 초보단계에 머물러 있다. 이러한 광섬유 센서 케이블 제작에 있어서 중요한 부분이 패키징 기술이라 할 수 있다. 이는 광섬유 센서를 일반적인 피복 구조로 패키징하게 되면, 센서 고유의 특성이 패키징 과정과 운반과정, 포설과정에서 변하게 되고 센서로써의 신뢰성이 크게 저하된다. 본 연구에서는 힘입자 감지용 광섬유 센서 케이블의 설계와 제작을 위한 제조공법을 확립하고, 이를 이용해 제작된 광섬유 센서 케이블의 신뢰성 특성을 평가하였다. 설계 제작된 광섬유 센서 케이블의 구조는 멀티모드광섬유(MMF) 에 0.9 mm Tight buffer를 코팅하고, 광심선 주위에 아라미드 얀을 삽입시킨 후 고문자 수지를 적용하여 외부 피복 (jacket)을 하였다. 제작된 광섬유 센서 케이블의 외경 측정결과 기준치 ($2.95\;{\pm}\;0.03$ mm)를 모두 만족하였고, 850 nm 파장에서의 광 손실 측정 결과 4.0 dB/km 이하였다. 또한 주요 항목의 신뢰성 특성 시험결과, 인장강도는 8~10 kg의 인장력을 갖으며 온도순환시험 ($-30^{\circ}C\;{\sim}\;+75^{\circ}C$)에서의 광 손실은 0.6 dB 이하로 나타나 침입자 감지용 광섬유 센서 케이블로 적합함을 확인할 수 있었다.