• The Journal of the Korea Contents Association
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• v.5 no.5
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• pp.202-210
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• 2005

The public Information systems for destination marketing have poorly operated and failed to satisfy tourists' needs. Public tourism website mainly offers fundamental tourism information such as transportation, lodging and prime attractions, which is mainly specialized in commercial web sites, and fails to attract tourists. For the public benefits, marketing strategy publicl DMOs have to specialize their tourism information, and attract specific target markets. Thus, this study examined the effect of tourism motivations on information search behavior to figure out the importance of tourism information. The results show that the level of escapist motivation positively to the perceived importance of fundamental informations, and the level of activist motivation effects positively to the perceived importance of objective-specific informations. These results give show problems of regional tourism information site and implications are suggested.

• Journal of the Korean Geosynthetics Society
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• v.12 no.2
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• pp.25-33
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• 2013

This study introduces strength characteristics of the anti-washout grouting material using viscous modifiers and its characteristics mixed with coarse materials. Especially, this study focused on the strength characteristics of the grouts mixed with sea water. It is found that the anti-washout grout mixed with sea water has enough strength and good resistance to segregation just like that with fresh water. Also, a small scale test was performed to evaluate the solidification characteristic of the anti-washout grout mixed with coarse fill materials. It is also found that the strength of anti-washout grout mixed with coarse fill materials is greater and better segregation resistance than those of conventional grout with fill materials.

• Journal of Digital Convergence
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• v.17 no.6
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• pp.185-192
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• 2019

The purpose of this study examines the effects of corporate CSR on corporate image, customer satisfaction, and customer citizenship behavior in order to provide implications for CSR. To verify hypotheses, we conducted a questionnaire survey on university students using Apple, Sony, Sharp, and Kyocera mobile phones, and used structural equation model analysis for 294 units. As a result, four factors, economic responsibility, legal responsibility, ethical responsibility and philanthropic responsibility were derived from corporate social responsibility, and all three factors except for ethical responsibility factors were proved to have a positive effect on corporate image. In addition, corporate image has a positive effect on customer satisfaction and customer civic behavior. As an implication, Japanese companies will need to take a systematic approach to CSR to help them understand their CSR and improve the level of CSR they can sympathize with.

• Journal of Oral Medicine and Pain
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• v.35 no.3
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• pp.165-175
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• 2010

Valproic acid (VPA) is a well-known anticonvulsive agent and has been used in the treatment of epilepsy for almost 30 years. VPA emerged in 1997 as an antineoplastic agent as well, when findings indicated the substance inhibited proliferation and induced differentiation of primitive neuroectocdermal tumor cells in vivo (Cinatl et al., 1997). Antitmor activity of VPA is associated with its targeting histone deacetylases. Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. This study was undertaken to investigate the synergistic apoptotic effect of co-treatment with the histone deacetylases inhibitor, VPA and a CDCA derivative, HS-1200 on human osteosarcoma (HOS) cells. Cell viability was evaluated by trypan-blue exclusion. Induction and augmentation of apoptosis were confirmed by Hoechst staining, flow cytometry (DNA hypoploidy and MMP change), Westen blot analysis and immunofluorescent staining. In this study, HOS cells co-treated with VPA and HS-1200 showed several lines of apoptotic manifestation such as nuclear condensations, the reduction of MMP, the decrease of DNA content, the release of cytochrome c into cytosol, the translocation of AIF onto nuclei, and activation of caspase-7, caspase-3 and PARP whereas each single treated HOS cells did not. Although the single treatment of 1 mM VPA or $25\;{\mu}M$ HS-1200 for 48 h did not induce apoptosis, the co-treatment of them induced prominently apoptosis. Therefore our data provide the possibility that combination therapy of VPA and HS-1200 could be considered as a novel therapeutic strategy for human osteosarcoma.

• Journal of Oral Medicine and Pain
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• v.36 no.1
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• pp.11-20
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• 2011

Valproic acid (VPA) is a well-known anticonvulsive agent and has been used in the treatment of epilepsy for almost 30 years. VPA emerged in 1997 as an antineoplastic agent. And it is known that antitmor activity of VPA is associated with its targeted at histone deacetylases. 17AAG, Inhibition of HSP90 leads to the proteasome degradation of the HSP90 client proteins, such as Akt, Raf/Ras, Erk, VEGF, cyclin D and p53, and causes potent antitumor activity. It is reported that 17AAG-induced HSP90 inhibition results in prevention of cell proliferation and induction of apoptosis in several types of cancer. This study was undertaken to investigate the synergistic apoptotic effect of co-treatment with the histone deacetylases inhibitor, VPA and the HSP90 inhibitor, 17AAG on human osteosarcoma (HOS) cells. Cell viability was evaluated by trypan-blue exclusion. Induction and augmentation of apoptosis were confirmed by Hoechst staining, flow cytometry (DNA hypoploidy and MMP change), Westen blot analysis and immunofluorescent staining. In this study, HOS cells co-treated with VPA and 17AAG showed several lines of apoptotic manifestation such as nuclear condensations, the reduction of MMP, the decrease of DNA content, the release of cytochrome c into cytosol, the translocation of AIF onto nuclei, and activation of caspase-3, caspase-7 and PARP whereas each single treated HOS cells did not. Although the single treatment of 1 mM VPA or 0.5 ${\mu}M$ 17AAG for 48 h did not induce apoptosis, the co-treatment with them induced prominently apoptosis. Therefore our data in this study provide the possibility that combination therapy with VPA and 17AAG could be considered as a novel therapeutic strategy for human osteosarcoma.

• Journal of Wetlands Research
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• v.19 no.1
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• pp.30-36
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• 2017

SS(Suspended Solid) concentration by soil erosion into river at normal and flood season should be measured. However, to present the variation of SS due to various development project such as EIA(Environmental Impact Assessment), River Master Plan, and so on, it is necessary to estimate not measure SS, but there are not exist how to estimate SS. In the present study, therefore, we propose the hydrologic method of estimating SS concentration using the results of particular frequency flood discharge and sediment discharge by RUSLE method. SS consists of silty and clay soil and colloid particle etc. However, in the present study, silty and clay soils of sediment discharge except send set up SS standards. The flow discharge to estimate SS concentration are 1~2 years for normal season, 30~100 years for flood season. Meanwhile, analysis software for probable rainfall uses Fard2006, probable rainfalls under 2-year frequency are estimated using rainfall data and frequency factor of Gumbel distribution. The results of estimating SS concentration using runoff volume by sediment and flow discharges of silty and cray soils as above method show that reliable level of SS concentration is considered in predevelopment of natural condition and under development of barren condition. Especially, SS concentration takes notice that the value of sediment discharge makes a huge difference according to channel slope, it was confirmed that the value obtained by dividing the SS concentration by the channel slope is relatively constant even though the topographical factors are different. Therefore, if the present study will be proceeded for various watersheds, it will be developed as estimation method of SS concentration.

• Proceedings of the Korea Water Resources Association Conference
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• 2006.05a
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• pp.1007-1011
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• 2006

본 연구에서는 어류 생태계 유지를 위해 필요한 생태학적 추천유량을 산정하고, 어류의 서식처 환경인 여울과 웅덩이의 형성조건을 검토함으로써 '작용'인 '흐름'과 '응답'인 '하상구조'와의 상관 관계를 규명하고자 하였다. 본 연구의 대상하천인 금호강에서는 하상변동이 활발한 자연 상태를 벗어나 하상의 이동성 상당히 둔화된 상태이며, 저수로내 여울과 웅덩이도 대표어종이 서식할 수 있는 자갈하상 구조에 변화가 일어나고 있는 것으로 분석되었다. 이것은 금호강 상류에 영천댐 건설의 영향이 어느 정도 미치고 있음을 유황분석 결과를 통해 간접적으로 파악할 수 있었다. 댐과 같은 수공구조물의 건설로 인하여 하도가 고정화된 상태에서 장기간에 걸치게 되면 여울과 웅덩이와 같은 하상구조가 축소되거나 소멸되어 금호강에서의 대표어종 서식처 환경에 영향을 미칠 것으로 추정된다. 금번 연구결과, 금호강에서 어류의 생식에 필요한 생태학적 추천유량 $8.2m^3/sec$가 필요하였으며, 어류의 서식처 환경인 여울과 웅덩이를 지속적으로 유지되기 위해서는 $250m^3/sec$ 이상의 유량이 연간 한번 이상 흘러야 하고, 2.5년 내지 3년 마다 약 $500m^3/sec$ 정도의 유량이 흐를 필요가 있다고 분석되었다. 본 연구 대상지점에서 흐름과 하상구조를 하천생태계와 연계해서 볼 때, 생태추천유량은 어디까지나 대표어종이 서식할 수 있는 최소조건에 불과하다. 대표어종이 장기간에 걸쳐 서식할 수 있는 하상구조가 존재하기 위해서는 대표어종이 선호하는 여울과 웅덩이가 필요하다. 결국 대표어종이 서식하기 위한 필요충분조건은 생태추천유량 확보와 아울러 대표어종이 선호하는 하상구조를 유지하기 위해서는 하도의 이동성을 유발할 유황변화가 필요하다는 것이 입증되었다.대상으로 연중 발생하는 큰 호우사상에 대해 임의의 강우관측소를 결측지점으로 가정하고 주변의 강우관측소로부터 각각의 방법을 이용해 가중치들을 산정하여 결측지점의 강우량 값을 보정하고자 하였다. 또한 각각의 방법을 이용하여 얻어진 결과에 대해 실측값과 보정값의 오차정도를 평균절대오차법(Mean Absolute Error)과 제곱평균제곱근오차법(Root Mean Squared Error)에 의해 산정하여 보정 방법간의 효율성을 검토하고자 하였다.9년, 그리고 2010년${\sim}$2019년까지 총 4구간으로 나누어 결과를 도출하였으며 예상한 바와 같이 후반기 20년 동안에 세 가지 지표가 취약해 지는 것을 확인할 수 있었고, 특히 2000년부터 2009년까지 10년 동안에는 더욱 취약해짐을 확인할 수 있었다.를 보임에 따라 그 정책적 효과는 때로 역기능적인 결과로 초래하였다. 그럼에도 불구하고 이 연구결과를 통하여 최소한 주식시장(株式市場)에서 위탁증거금제도는 그 제도적 의의가 여전히 있다는 사실이 확인되었다. 또한 우리나라 주식시장에서 통상 과열투기 행위가 빈번히 일어나 주식시장을 교란시킴으로써 건전한 투자풍토조성에 저해된다는 저간의 우려가 매우 커왔으나 표본 기간동안에 대하여 실증분석을 한 결과 주식시장 전체적으로 볼 때 주가변동율(株價變動率), 특히 초과주가변동율(超過株價變動率)에 미치는 영향이 그다지 심각한 정도는 아니었으며 오히려 우리나라의 주식시장은 미국시장에 비해 주가가 비교적 안정적인 수준을 유지해 왔다고 볼 수 있다.36.4%)와 외식을 선호(29.1%)${\lrcorner}$ 하기 때문에 패스트푸드를 이용하게 된 것으로 응답 하였으며, 남 여 대학생간에는 유의한 차이(p<0.05)가 인정되었다. 응답자의 체형은 ${\ulco

• The Journal of Korean Institute of Communications and Information Sciences
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• v.25 no.4A
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• pp.573-578
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• 2000

This paper presents a noble optical access system using shared laser and LED light sources, which is based on WDM-PON technologies. This system adopts an external modulation of the shared laser sources for high-speed downstream and a direct modulation of the LED sources for low-speed upstream. To split or combine the transmission channels, AWG(Arrayed Wave-guide Grating) devices are used in the optical cable section. The proposed system is attractive for low cost implementation. The laser light sources can share the optical carriers in the downstream scheme. Also, in upstream, the LED sources can afford to make simple of the circuits for controlling light source and of standardization for ONU(Optical Network Unit). The feasibility of the proposed system is demonstrated by several experiments. Our results show that the system operates well at 2.SGbps for downstream and up to 622.08Mbps for upstream.

• Aerospace Engineering and Technology
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• v.13 no.2
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• pp.7-17
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• 2014

This technical paper deals with development of on-board orbit generation algorithm for GEO Satellite. This paper presents the research analysis results performed in order to improve the accuracy of the existing algorithm used for generating real-time orbit information for GEO satellite. The error impact on orbit accuracy due to the orbit error sources were analyzed with the algorithm suggested by this research. As a result of the analyses, it is found that the initial orbit should be determined with an accuracy of less than 50 m and the reference position angle error for the ground station and the satellite should be maintained within ${\pm}0.0025deg$ in order to meet the orbit accuracy specification. The development of on-board flight software based on the new algorithm was accomplished and the performance verification is ongoing by using a software based performance verification tool.

• Korean Journal of Crystallography
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• v.3 no.2
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• pp.120-128
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• 1992

Single crysals of BaTiO3 were grown by TSSG technique at various cooling rates. Morpolo girts, defects and domain structures of the grown crystals were investigated. At the cooling rates below 0.5℃/hr, equant single crystals were obtained and the 11111 faces were dominantly developed. If the cooling rate was much faster or if the vortical temperature gradient in the so lotion was very large, the solution became unstable and the needle formed BasTil04 o crystals were precipitated. Two sets of parallel lamella domains are arranged perpendicular to each other and the irregularly shaped boundaries are fixed between them. These sets of domains show remarkable orientation contrast in x-ray topography. Heating the crystal above 127℃, the phase transition from tetragonal to cubic occurs. The phase transition front (PTF) moves in the direction of temperature gradient. Domains in the tetragonal phase are successively rearranged and regular strain patterns appear in the cubic phase. The habit plane of PTF in BaTi03 is found to deviate from a l1101 lattice plane by app roximately 9°.