• Journal of Convergence for Information Technology
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• v.8 no.5
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• pp.45-50
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• 2018

The functional nanomaterials of fluorescent dye-doped silica nanoparticles(NPs) are applied to bio applications such as bio-labeling of DNA micro-array, and bio-imaging. Organic dye-doped fluorescent silica NPs exhibit excellent bio-compatibility, non-toxic, and highly hydrophilic properties. In this study, organic fluorescent dyes were dissolved in ethanol, and deionized(DI) water. Organic fluorescent dyes were physically adsorbed to silica NPs and chemically doped to silica NPs. The fluorescence characteristics(FLC) was investigated by UV lamp irradiation of 365 nm wavelength. As results, the FLC of dye-doped silica NPs exhibits better than dye-adsorbed silica NPs and the FLC was improved with the increase of concentration of doped-dyes. The fluorescent organic dyes were well dissolved in ethanol than DI water. The photostability of dye-doped silica NPs was superior than pure fluorescent organic dye. The FLC of optimized dye-doped silica NPs would be applied to agent of non-invasive fluorescence bio-imaging in live cell and in vivo.

• Journal of Life Science
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• v.31 no.10
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• pp.885-897
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• 2021

Schisandrae Fructus (SF) and Corni Fructus (CF) have been used for a long time for the prevention and treatment of various diseases. Although reports have highlighted the possibility of inhibiting the onset and progression of benign prostatic hyperplasia (BPH), studies on related mechanisms are still lacking. In this study, we investigated the potential of SF and CF in improving BPH by using a dihydrotestosterone (DHT)-induced in vitro BPH model using LNCaP prostate carcinoma cells. According to our results, water and ethanol extracts of SF and CF significantly inhibited the proliferation of LNCaP cells by DHT treatment and markedly downregulated the expression of DHT-induced BPH biomarkers and growth factors. They also regulated the expression of apoptosis regulatory factors and significantly reduced DHT-mediated oxidative stress. In addition, the protective effect on major factors involved in the pathogenesis of BPH was more effective in the ethanol extract treatment group than in the water extract group. Furthermore, the improvement effect on BPH was higher in the 1:1 combined treatment group than in the ethanol extract alone treatment group of SF and CF, and 60% ethanol extracts showed a better effect than 40% ethanol extracts. Therefore, our findings demonstrate that SF and CF can protect against BPH by preventing the hyperproliferation of prostate cells through the inhibition of the androgen signaling pathway, which was correlated with their antioxidant activities. Therefore, SF and CF extracts may be useful in the clinical treatment of BPH, and the combination of these two extracts can be synergistic.

• Journal of the Korean Wood Science and Technology
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• v.36 no.4
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• pp.102-108
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• 2008

At the University of Maine, a hemicellulose pre-extraction technology is now being investigated to improve pulp yields, reduce the organic and inorganic load for liquor recovery, and create a feed stream for the generation of new biomaterials. It is important to understand the composition of unextracted wood, extracted wood, and pulping extracts in the design of an economically viable pilot-scale ethanol plant. For analysis of wood pulp composition, the total analytical mass balance closure was 100.6, 100.3, and 81.6% for unextracted chips, extracted chips, and pulping extracts from HPLC-H column analysis. Meanwhile, the total analytical mass balance from the HPLC-P column was 97.8, 86.3, and 80.7%, respectively. This slight variability between H- and P-column results for analytical mass balance may be within the experimental error of the measurement. The data generated by this analysis are important to further design work in commercializing this process.

• Transactions of the Korean hydrogen and new energy society
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• v.27 no.6
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• pp.712-720
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• 2016

When bioethanol and water are mixed at a proper ratio, phase separation can occur because of the immiscibility of biobutanol with water. Phase separation in bioethanol blends fuels is a major problem for gasoline vehicle users due to effect of octane number and component corrosion. Thus, in this study, the phase separation of bioethanol was examined effect of bioethanol blends (E3 (3 vo.% bioethanol in gasoline), E5 and E10) in presence of water. The effect were evaluated behavior with phase separation test, simulation test of fuel tank in gas station according to water addition volume and it was investigated change of water content, bioethanol content and octane number for gasoline phase in bioethanol blends (E3, E5 and E10) every 1 week after water addition. The E3 occurred phase separation more easily than the E5 and E10 in small water contents because solubility of water on ethanol content difference in gasoline-ethanol. It was kept a initial level of water content, bioethanol content, and octane number by repeated sample replacing in simulation test of fuel tank.

• Korean Chemical Engineering Research
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• v.49 no.4
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• pp.470-474
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• 2011

Rice straw is the main grain straw and is produced in large quantities every year in Korea. Pretreatment of lignocellulosic biomass using soaking process was carried out mild conditions at atmospheric pressure and temperature of $60^{\circ}C$. We found enzymatic hydrolysis condition of pretreated biomass. In case of a rice straw, compared with previous lignocellulosic biomass, we found that hydrolysis time was a shorter than others. Hydrolysis of SAA-treated rice straw has shown conversion rate was higher at $50^{\circ}C$. Hydrolysis was ended between 40~48 hour. Glucose conversion rate was higher when enzyme loading is 65 FPU/ml and 32 CbU/ml. When substrate concentration was 5%(w/v), it was that conversion rate was 83.8% after hydrolysis for 72 hr. In simultaneous saccharification and fermentation(SSF) experiment about SAA-treated rice straw, ethanol productive yield was highest from $40^{\circ}C$. The yield of that time was 33.05% from 48 hour.

• Proceedings of the Korea Forestry Energy Research Society Conference
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• 2011.02a
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• pp.120-123
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• 2011

• Proceedings of the Korea Air Pollution Research Association Conference
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• 2009.10a
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• pp.327-328
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• 2009

• Fire Science and Engineering
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• v.30 no.3
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• pp.1-6
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• 2016

More than five thousands transportation fires occurannually in Korea and the resulting destruction of property and loss of life is huge and results in traffic and environmental pollution. The recent development of automobile technology such as the hybrid concept and use of bio fuels makes fire protection even more difficult due to a lack of understanding of the new adapted system including vehicle engines. In this study, a numerical simulation was performed on a PSR (perfectly Stirred Reactor) to simulate an automobile engine and to clarify the effect of gasoline/ethanol surrogates as a fuel. The temperature, NOx and soot emissions were predicted to decrease with increasing ethanol content, but that of unburned hydrocarbons was found to increase dramatically. The result will provide not only the basic thermal characteristics for engines and their after-treatment systems, but also make it possible to assess the potential for fire events in these systems when an ethanol mixed fuel is used in gasoline vehicles.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.5
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• pp.420-427
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• 2017

Recently, the depletion of fossil fuels, global warming and environmental pollution have emerged as a worldwide problem, and studies of new renewable energy sources have been progressed. Among the many renewable energy sources, the use of bio fuel has the potential to displace fossil fuels due to low price, easy to handle, and the abundant sources. Pyrolysis oil (PO) derived from waste wood and sawdust is considered an alternative fuel for use in diesel engines. On the other hand, PO is limited to diesel engines because of its low cetane number, high viscosity, high acidity, and low energy density. Therefore, to improve its poor properties, PO was mixed with alcohol fuels, such as ethanol. Early mixing with ethanol has the benefit of improving the storage and handling properties of the PO. Furthermore, a PO-ethanol blended fuel was injected separately, which can be fired through pilot-injected diesel in a dual-injection diesel engine. The experimental results showed that the substitution of diesel with blended fuel increases the amount of HC and CO, but reduces the NOx and PM significantly.

• Transactions of the Korean Society of Automotive Engineers
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• v.18 no.1
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• pp.37-43
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• 2010

The purpose of this paper is to investigate the effect of air-fuel ratio on the combustion and emissions characteristics of spark ignition (SI) gasoline engine fueled with bio-ethanol. A 1.6L SI engine with 4 cylinders was tested on EC dynamometer. In addition, lambda sensor and lambda meter were connected with universal ECU to control the lambda value which is varied from 0.7 to 1.3. The engine performance and combustion characteristics of bio-ethanol fuel were compared to those obtained by pure gasoline. Furthermore, the exhaust emissions such as carbon monoxide (CO), unburned hydrocarbon (HC), oxides of nitrogen ($NO_X$) and carbon dioxide ($CO_2$) were measured by emission analyzers. The results showed that the brake torque and cylinder pressure of bio-ethanol fuel were slightly higher than those of gasoline fuel. Brake specific fuel consumption (BSFC) of bio-ethanol was increased while brake specific energy consumption (BSEC) was decreased. The exhaust emissions of bio-ethanol fuel were lower than those of gasoline fuel under overall experimental conditions. However, the specific emission characteristics of the engine with bio-ethanol fuel were influenced by air-fuel ratio.