• Journal of the KSME
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• v.52 no.6
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• pp.35-38
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• 2012

이 글에서는 나노/마이크로 캔틸레버 구조물을 이용한 나노 기계적 바이오-화학센서의 구조/작동원리, 신호 측정 방법 및 다양한 응용분야에 대해 소개하고자 한다.

• KSBB Journal
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• v.22 no.6
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• pp.378-386
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• 2007

Bio-sensing devices, which are basically integrated and miniaturized assay systems consisted of bioreceptor and signal transducer, are advantageous in several ways. In addition to their high sensitivity, selectivity, simplicity, multi-detection capability, and real time detection abilities, they are both very small and require relatively inexpensive equipments. Two core technologies are required to develop bio-sensing devices; the fabrication of biological receptor module (both of receptor development and immobilisation of them) and the development of signal transducing instruments containing signal generation technique. Various biological receptors, such as enzymes, DNA/RNA, protein, and cell were tried to develop bio-sensing devices. And, the signal transducing instruments have also been extensively studied, especially with regard to electrochemical, optical, and mass sensitive transducers. This article addresses bio-sensing devices that have been developed in the past few years, and also discusses possible future major trends in these devices.

• Proceedings of the Optical Society of Korea Conference
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• 2006.07a
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• pp.35-35
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• 2006

• Information and Communications Magazine
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• v.25 no.2
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• pp.54-62
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• 2008

본 고에서는 바이오 정보, 특히 호흡 및 심박수 측정을 위한 바이오 레이더의 원리 및 최근 연구동향을 살펴본다. 바이오 레이더는 무선을 이용하여 비접촉 방식으로 심박 및 호흡 신호를 측정할 수 있어, 향후 u-헬스케어의 핵심 기술중의 하나로 고려되고 있으며, 최근 관련 연구가 전세계적으로 활발히 진행되고 있다. 하지만 실제 상용화되는 데는 아직도 많은 난관이 있어 이를 극복하려는 기술 개발 및 지속적인 관심이 필요하다.

• Proceedings of the Optical Society of Korea Conference
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• 2008.02a
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• pp.271-272
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• 2008

• Journal of Korea Fair Competition Federation
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• no.102
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• pp.17-31
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• 2004

경쟁정책은 기술혁신의 양과 기술이전, 즉 라이센싱, 그리고 제품의 가격과 생산량에 영향을 미친다. 문제는 이 3개의 항목 중 어디에 경쟁정책의 초점이 맞추어져야 하는가이다. 전통적으로 경쟁정책은 생산량과 가격의 움직임에 관심을 가졌는 바, 이제 지식경제화 시대에서 특히 지적재산권 분야에서는 혁신의 확산의 경쟁적 효과에 초점을 맞추어야 할 필요가 있다. 즉 라이센싱의 경쟁적 효과를 면밀히 분석해야 하는 것이다.

• Microbiology and Biotechnology Letters
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• v.43 no.4
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• pp.357-366
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• 2015

Quorum sensing (QS) is involved in the process of cell-to-cell communication and as a gene regulatory mechanism, which has been implicated in bacterial pathogenicity. Bacteria use this QS system to control a variety of physiological processes. In this study, pomegranate (Punica granatum L.) peel extract (PPE) was first screened for its ability to inhibit QS in bio-reporter strains (Chromobacterium violaceum and C. violaceum CV026). Next, the ability of PPE to inhibit swimming motility and biofilm formation was examined in Y. enterocolitica. Additionally, changes in the expression of specific genes involved in the synthesis of the N-acylhomoserine lactones (AHLs; yenI and yenR) and in the flagellar regulon (fliA, fleB and flhDC) were evaluated by reverse transcription (RT)-PCR. The results show that PPE specifically inhibited and reduced QS-controlled violacein production by 78.5% in C. violaceum CV026, and decreased QS-associated biofilm formation and swimming motility in Y. enterocolitica without significantly affecting bacterial growth. These inhibitory effects were also associated with the down-regulation of gene expression involved in the synthesis of AHLs and in motility. Our results suggest that PPE could be a potential therapeutic agent to prevent enteropathogens in humans, as well as highlight the need to further investigate the in vivo properties of PPE for clinical applications.

• Magazine of the Korean Society of Agricultural Engineers
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• v.53 no.3
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• pp.57-63
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• 2011

• 대한치주과학회:학술대회논문집
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• 2008.05a
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• pp.15-15
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• 2008

• The Magazine of the IEIE
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• v.32 no.8 s.255
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• pp.52-61
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• 2005