• Title/Summary/Keyword: 바이오헬스

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Directions of Convergence Technology Education related to New Industry Field through Analysis of Industrial Needs (산업체 요구분석을 통한 신산업 융합기술교육의 방향)

  • Jin, Sung-Hee
    • Journal of the Korea Convergence Society
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    • v.10 no.8
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    • pp.105-113
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    • 2019
  • Convergence education, which is operated by many engineering colleges, is mainly led by government-led projects. Convergence majors are established in consideration of the research field of the university professors rather than systematically analyzing the needs of the industry. The purpose of this study is to present the directions of convergence technology education related to new industry fields by analyzing industry needs. Participants were 299 industrial workers in various fields. Instrument consisted of three parts: necessity for convergence education, demand for convergence new technology education from industry perspective, and opinions about undergraduate convergence education. As a result, it was found that the level of awareness of industry needs for fusion technology education was high, and it was confirmed that there is a high demand for IoT convergence, bio-health, advanced new material, and renewable energy fields among convergence technology fields. In addition, the results of the industry demand for convergence new technology education were presented. The suggestions for expectations, problems, and improvements in undergraduate education were presented and implications for convergence technology education were discussed based on the results of the study.

Factors Influencing Medical Care Utilization according to Decline of Region: Urban Decline Index and Medical Vulnerability Index as Indicators (지역쇠퇴 유형별 의료이용행태 영향요인: 도시쇠퇴 지표와 의료취약지 지표를 활용하여)

  • Jeong, Ji Yun;Jeong, Jae Yeon;Yoon, In Hye;Choi, Hwa Young;Lee, Hae Jong
    • Health Policy and Management
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    • v.32 no.2
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    • pp.205-215
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    • 2022
  • Background: The purpose of this study is to identify the factors infecting the medical care utilization from a new perspective by newly classifying the categories of administrative districts using the urban decline index and medical vulnerability index as indicators. Methods: This study targeted 150,940 people who used medical services using the 2015 cohort database (DB), 2010-2015 urban regeneration analysis index DB, and 2014-2015 public health and medical statistics DB. The decline of the region was classified using the urban decline index typed using k-means clustering and the medical vulnerability index typed using the quantile score calculation. Regression analysis was performed 3 times with medical expenditure, length of stay, and the number of outpatient visits as dependent variables. Results: There were 37 stable region (47.4%), 29 health vulnerable region (37.2%), and 12 decline region (15.4%). The health vulnerable region had lower medical expenditure, fewer outpatient visits, and a higher length of stay than the stable region. The decline region was all higher than the stable region but had no significant effect. Conclusion: The factors that cause the health disparity between regions are not only factors related to individual health behavior but also environmental factors of the local community. Therefore, there is a need for a systematic alternative that properly considers the resources within the community and reflects the characteristics of the population.

The Effect of Anti-microbial and the Inhibitory Effect of Biofilm Formation and Inflammatory Factors Production of Perillae semen Supercritical Fluid Extracts (초임계 자소자추출물의 항균효과와 바이오필름, 염증매개인자 생성 억제 효능)

  • Lee, Kwang Won;Park, Shinsung;Park, Su In;Shin, Moon Sam
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.6
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    • pp.615-624
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    • 2022
  • In this study, we assessed anti-oxidant activity, anti-microbial, inhibition of biofilm formation and inflammatory factors(nitric oxide, interleukin-6, interleukin-8) inhibitory effect of Perillae semen hydrothermal extract(PSW) and three kinds of Perillae semen supercritical fluid extract(PSSs) extracted by controlling temperature with no variation of pressure. Compared with PSW, PSSs had significantly lower minimal inhibitory concentrations(MICs) against Staphylococcus aureus(S. aureus) and the ability of PSSs to inhibit formation of biofilm was also superior. PSSs reduce the production of inflammatory mediator and inflammatory cytokines significantly compared to PSW. We suggest, therefore, Perillae semen supercritical fluid 45℃ extract which showed the best anti-microbial, inhibition of biofilm formation, and inhibition of inflammatory factors production among the supercritical fluid extracts could be used for protecting patients with atopic dermatitis from pruritus and transepidermal water loss as a functional ingredient from nature.

Photobiomodulation Mediated by Red and Infrared Light: A Study of Its Effectiveness on Corneal Epithelial Cells and Wound Healing (적색 및 적외선 빛을 이용한 Photobiomodulation: 각막상피세포에 대한 효과와 상처 치유에 관한 연구)

  • Sun Hee Ahn;Jae Sung Ahn;Byeongil Lee
    • Korean Journal of Optics and Photonics
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    • v.34 no.2
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    • pp.45-52
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    • 2023
  • In this study, we have investigated the effect of photobiomodulation (PBM) on corneal wound healing, using a low-power light-emitting diode (LED) at different wavelengths. We found that LEDs with wavelengths ranging from 623 to 940 nm had no significant cytotoxic effects on corneal epithelial cells. The effect of PBM on promoting cell migration was analyzed by scratch assay, and it was found that PBM at 623 nm significantly increased cell migration and promoted wound healing. Furthermore, the expression of genes related to cell migration and wound healing was analyzed, and it was found that PBM at 623 nm upregulated the expression of the genes FGF-1 and MMP2, which are known to promote cell proliferation and extracellular matrix degradation. These findings suggest that PBM with low-powered light at specific wavelengths, particularly 623 nm, could be utilized to treat corneal injury.

Case Study on Amorepacific : Focusing on Analysis of Competitive Advantage through Diamond Model (아모레퍼시픽에 대한 사례연구: 다이아몬드 모델을 통한 경쟁우위 분석을 중심으로)

  • Shin, You-jin;Park, Sang-hyeon
    • Journal of Venture Innovation
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    • v.4 no.2
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    • pp.43-55
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    • 2021
  • Based on the modifier 'K', the Republic of Korea has been drawing attention from around the world in various fields. Therefore, if you look at a representative field, it can be called the beauty, that is, the cosmetics industry. In particular, paying attention to the fact that interest in appearance has been increasing in recent years, regardless of age or gender, we intend to explore ways to create competitiveness in the industry. In particular, from this perspective, we tried to deal with the company case of AMOREPACIFIC, one of Korea's leading cosmetic companies, and seek the direction of development through analysis of corporate competitiveness. Therefore, as an analysis method for this study, we tried to subdivide and examine the factors that have been possible for a company to succeed using the diamond model of Michael Porter. Based on the factors derived after that, we intend to present the direction for the company to discharge in the future.

Effect of Dictyopteris divaricata Extracts on Adipogenesis in 3T3-L1 Preadipocytes (미끈뼈대그물말(Dictyopteris divaricata) 추출물의 항비만 효과)

  • Chul Hwan Kim;Seok-Chun Ko;Hyun-Soo Kim;Gun-Woo Oh;Ji-Yul Kim;Kyung Woo Kim;Jeong Min Lee;Myeong-Seok Lee;Yun Gyeong Park;Gyeong Lee;Jae-Young Je;Jung Hye Won;Young Jun Kim;Dae-Sung Lee
    • Journal of Marine Bioscience and Biotechnology
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    • v.15 no.2
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    • pp.59-66
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    • 2023
  • Dictyopteris divaricata, a type of marine brown algae, has been studied for its various biological properties, including anti-inflammatory, antidiabetic, and whitening effects. However, its potential antiobesity effects have not been extensively explored. This study aimed to examine the impact of D. divaricata ethanol extract (DDE) on adipocyte differentiation and adipogenesis using 3T3-L1 preadipocytes. Our results showed that when 3T3-L1 preadipocytes were treated with noncytotoxic concentrations of DDE there was a concentration-dependent decrease in fat accumulation rate and triglycerid production compared with the control. Furthermore, DDE significantly reduced the expression of transcription factors (PPARγ, C/EBPα, and SREBP-1) and fatty acid transport protein (FABP4), which are crucial for 3T3-L1 preadipocyte differentiation. These findings suggest that DDE may exhibit antiobesity effects by suppressing the expression of lipogenic transcription factors and fatty acid transport proteins. Therefore, DDE holds potential as a therapeutic agent for obesity.

Effect of Astragalus membranaceus-postbiotics Polysaccharide Changed by Lactic Acid Bacteria on Macrophage (유산균에 의해 변화된 황기-포스트바이오틱스 다당류가 대식세포에 미치는 영향)

  • Yeon Suk Kim;Hyun Young Shin;Won Bi Jeong;Eun Ji Ha;Ja Pyeong Koo;Ji-Young Shin;Kwang-Won Yu
    • The Korean Journal of Food And Nutrition
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    • v.37 no.1
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    • pp.17-29
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    • 2024
  • To increase industrial applicability of Astragalus membranaceus (AM) as immunostimulating materials, hot-water extract (AME) was prepared from AM and fermented with Kimchi-lactic acid bacteria (Lactobacillus sakei & Leuconostoc mesenteroides) to prepare fermented AM-postbiotics (FAME). Although FAME prepared from AM-postbiotics did not show a significant enhancement in macrophage stimulating activity compared to non-fermented AME, crude polysaccharide (FAME-CP) fractionated by EtOH precipitation from FAME showed significantly higher macrophage stimulating activity than AME-CP. Compared to AME-CP, FAME-CP showed dramatic changes in component sugar and molecular weight distribution. FAME-CP was a polysaccharide with a major molecular weight distribution of 113.4 kDa containing Man (44.2%), Glc (19.3%), Gal (10.2%), GalA (10.2%), and Ara (7.4%) as sugar components. FAME-CP with enhanced macrophage stimulatory activity not only increased expression levels of mRNA genes encoding macrophage-activated factors (iNOS, TNF-α, MCP-1, IL-6, and COX-2), but also led the nuclear translocation of activated p65 and c-Jun. In conclusion, crude polysaccharide from AM-postbiotics fermented with lactic acid bacteria could increase industrial applicability as a functional material with enhanced immunostimulating activity than AME-CP.

An IT Convergent Service Engineering Model based on the Dynamic Innovation Theory (동태적 혁신이론 기반의 IT 융합 서비스공학 모델)

  • Kim, Jong-Ho
    • 한국경영정보학회:학술대회논문집
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    • 2007.11a
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    • pp.349-355
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    • 2007
  • 최근, 맞춤의료서비스, 헬스와 웰빙의 복합서비스, RFID 기반의 공급망 관리 서비스와 같이 정보기술(IT), 바이오기술(BT), 나노기술(NT) 등이 융합된 혁신적인 서비스들이 출현하고 있다. 그러나 기존의 전통적인 접근방법으로는 새로이 출현하는 다양한 서비스에 대한 체계적인 접근이 불가능하다. 따라서 분석의 단위를 조직이나 정보 시스템 수준에서 서비스 수준으로 하향하는 것과 요소기술이 서비스로 변환되어 소비자에게 수용되는 전체과정을 동태적, 공학적으로 설계하는 접근이 절실히 요구된다. 본 연구의 목적은 신 기술의 출현, 성숙, 시장으로의 유입과 소비자에 수용되는 서비스 생명주기 전 과정을 통태적 관점에서 분석하는 틀을 제시하고 의료서비스에 특화 하여 서비스 공학적 관점에서 IT, BT, NT가 융합된 서비스를 설계하는 모델을 제시하는 것이다. 이를 위해 우선 서비스의 특성과 서비스 시스템 설계의 목표를 제시하고 동태적 혁신이론에 기반하여 서비스의 탄생부터 시장에서의 수용에 이르는 생명주기를 표현할 수 있는 모델을 개발한다. 이 모델의 시간 축을 분기하여 단계(Stage)들을 도출하고 각 단계에서 수행해야 할 활동들을 설계한다. 아울러 모델의 실제적 유용성을 입증하기 위하여 의료분야의 관련사례를 제시하고 조직의 서비스전략과 다변화 전략을 수립하기 위한 논리도 제시하였다. 본 연구의 동태적 공학모델은 IT 생태계 (IT Ecosystem) 하에서 조직 및 IT 요소들이 다양한 환경에서 어떻게 안정적이고 효율적인 메커니즘을 형성하고 진화해야 하는지를 잘 보여주고 있다.

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Optical Characterization of Light-Emitting Diodes Grown on the Cylinder Shape 300 nm Diameter Patterned Sapphire Substrate (300 nm Diameter Cylinder-Shape 나노패턴 기판을 이용한 LEDs의 광학적 특성)

  • Kim, Sang Mook;Kim, Yoon Seok
    • Korean Journal of Materials Research
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    • v.29 no.1
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    • pp.59-64
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    • 2019
  • This study investigates the optical characteristics of InGaN multiple quantum wells(MQWs) light emitting diodes(LEDs) on planar sapphire substrates(PSSs), nano-sized PSS(NPSS) and micro-sized PSS(MPSS). We obtain the results as the patterning size of the sapphire substrates approach the nanometer scale: The light from the back side of the device increases and the total light extraction becomes larger than the MPSS- and planar-LEDs. The experiment is conducted by Monte Carlo ray-tracing, which is regarded as one of the most suitable ways to simulate light propagation in LEDs. The results show fine consistency between simulation and measurement of the samples with different sized patterned substrates. Notably, light from the back side becomes larger in the NPSS LEDs. We strongly propose that the increase in the light intensity of NPSS LEDs is due to an abnormal optical distribution, which indicates an increase of extraction probability through NPSS.

Effect of Job Embeddedness and Organization Attachment on Intention to Stay in Hospital Nurses (병원간호사의 직무배태성과 조직애착이 잔류의도에 미치는 영향)

  • Go, Younghye;Jeong, Hyun
    • Journal of the Korea Convergence Society
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    • v.12 no.11
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    • pp.511-519
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    • 2021
  • This study aimed to identify the effect of job embeddedness and organization attachment on the intention to stay of hospital nurses in the convergence society. The participants were 211 general hospital nurses; data were analyzed using t-test, ANOVA, Pearson correlation, Multiple regression. This study found that: hospital nurses showed higher score at job embeddedness, higher organization attachment, higher scores for intention to stay. The main factors influencing intention to stay were job embeddedness and organization attachment. They explained about 45% of the intention to stay. Thus, it is necessary to allocate tasks and evaluate appropriate to the nurse's ability and support individual and organizational activities that can enhance organizational attachment.