• Journal of Nutrition and Health
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• v.54 no.4
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• pp.412-421
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• 2021

Purpose: Thioacetamide (TAA) produces reactive oxygen species (ROS) in the liver, and the generated ROS induces liver injury through inflammatory reactions. The current study was undertaken to investigate the hepatoprotective effect of Artemisiae Capillaris Herba water extract (AC), imparted via its antioxidant activity, in an animal model of TAA-induced liver injury. Methods: Animal experiments were conducted in 5 groups: normal, control (TAA 200 mg/kg), SM (TAA 200 mg/kg + silymarin 100 mg/kg), ACL (TAA 200 mg/kg + AC 100 mg/kg), ACH (TAA 200 mg/kg + AC 200mg/kg). TAA (intraperitoneal) and treatment compounds (per oral) were administered for 3 days. Serum levels of ammonia concentration and myeloperoxidase (MPO) activity were subsequently measured. Liver tissues were subjected to western blot analysis for measuring the oxidative stress (NADPH oxidase), anti-oxidative activity (Nrf2, heme oxygenase-1 [HO-1], superoxide dismutase [SOD], catalase, and GPx-1/2), tissue inhibitors of metalloproteinase (TIMP)-1, and matrix metalloproteinases (MMPs) protein expressions. Results: Serum ammonia levels and MPO activity were significantly increased in the TAA-induced control group, whereas groups administered AC treatment showed markedly reduced levels. Western blot analysis revealed significantly increased NOX2 and p22^phox expressions, (oxidative stress-related factors) in the TAA-induced control group. These levels were determined to be significantly decreased after AC exposure. Moreover, antioxidant-related factors including Nrf2, HO-1, SOD, catalase, and GPx-1/2 were significantly decreased in the control group and increased in the AC treated groups. In addition, MMP expressions were significantly suppressed in the AC treatment group due to increased levels of TIMP-1. Conclusion: Taken together, these data indicate that exposure to AC reduces the oxidative stress by inhibiting the expression of NADPH oxidase (NOX2 and p22^phox) through the Nrf2 signaling pathway. We therefore propose the potential of AC for the prevention and treatment of TAA-induced liver injury.

• The Journal of the Convergence on Culture Technology
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• v.7 no.3
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• pp.197-202
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• 2021

This paper focuses on the situation in which, as pluralistic democracy spreads globally from the mid-20th century, the concept of publicness, the reason for the existence of traditional public art, is not limited to the physicality of occupying public space or the conditions for creation by public funds, but is seeking a new direction and examine the social significance of these changes. For this purpose, the main body of this paper analyzes the major public art projects of Freee Art Collective who were active in the UK in the early 2000s. Freee performed various public art projects in which individuals constituting a community critically reflect on political, social, and economic issues related to public goods and provide a discourse space for democratic discussion. Their practice suggested a methodology for socially-engaged public art that resists the "Third Way" cultural policy of the New Labour administration. Therefore, this paper argues that Freee's public art seeks alternatives to publicness in that it allows one to resistively think about problematic aspects of hegemonic cultural production of neoliberal cultural policy that pursues political consensus and social harmony. This research about Freee's public art would be significant in that it can serve as an opportunity for critical reflection on the contemplative form and public role of contemporary public art.

• The Journal of the Korea Contents Association
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• v.21 no.5
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• pp.234-246
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• 2021

The purpose of this study is to develop the main subjects of the job-based curriculum by deriving the job analysis results of general security job workers in the physical protection field responsible for responding to threats to nuclear materials and nuclear facilities. In the job analysis stage, FGI was conducted on 7 content experts to derive 8 duties and 55 tasks. In addition, knowledge and skills were drawn for each task. In the analysis of educational needs, surveys were conducted for workers in general security jobs to derive the top 25 educational priorities through t-test and Borich needs assess model. At the stage of selecting core tasks and organizing required/optional contents, 42 tasks, both above average or at least one of them, were derived as core tasks based on the result of evaluation of importance and difficulty ratings of 55 tasks through a questionaire. In addition, tasks applied to the top 25 rankings derived from Borich needs assess model were applied as the required contents when designing courses, and tasks which applied only one of them were selected as optional contents. At the stage of required/optional modules and educational contents, four required modules and five optional modules were derived by drifting similar tasks between the required and optional contents. Based on the above results, the study suggested academic and practical implications and future suggestions.

• Land and Housing Review
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• v.13 no.1
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• pp.99-112
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• 2022

There is growing significance in securing urban parks and enhancing their accessibility due to irrational residential developments and apartment construction. Accordingly, Daejeon Metropolitan City has carried out urban park management projects to improve the quality of parks and create new parks. Daejeon Metropolitan City generates and manages park data for the purpose of management by the administrative district. However, these datasets take different forms in each administrative district. This study integrates the park data in Daejeon, generated by administrative districts, into the same format and generates geographic information data with the area information of each park for analysis. Analysis results show that urban parks are severely imbalanced across administrative districts, requiring new policy measures. In addition, by normalizing the park analysis results and, then, creating their rankings, this study compares them with the actual park information in detail to confirm the soundness of the dataset. The analysis results provide implications to improve the management of urban parks. This study proposes integrated datasets and the continued management of them in each administrative district by including essential data that can feature the objective information of the parks along with park evaluation indicators based on previous studies.

• Journal of Marine Life Science
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• v.6 no.2
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• pp.97-105
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• 2021

Tegillarca granosa, is one of the most important fishery resources throughout Asia. However, due to industrialization factories, marine environmental pollution, and global warming, the marine fishery production has drop sharply. In order to understand the genetic factors of the blood clam, which is a major fishery resource on the southern coast of Korea, the whole genome of blood clam was studied. The assembled genome of T. granosa was 915.4 Mb, and 19 chromosomes were identified. 25,134 genes were identified, and 22,745 genes were functionally annotated. As a result of performing gene gain and loss analysis between the blood clam genome and eight other types of shellfish, it was confirmed that 725 gene groups were expanded, and 479 gene groups were contracted. The homeobox gene cluster of blood clam showed a well-preserved genetic structure within lophotrochozoan ancestor. T. granosa genome showed high similarity between three hemoglobin genes with Scarpharca broughtonii. The blood clam genome will provide information for the genetic and physiological characteristics of blood clam adaptation, evolution, and the development of aquaculture industry.

• Informatization Policy
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• v.28 no.4
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• pp.19-35
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• 2021

The purpose of this research is to investigate the attributes of the online world and to analyze their influence on democracy. The research focuses on the mayoral by-elections that were held in Seoul and Busan, South Korea, on April 4, 2021. The study demonstrates the characteristics of online spaces and the polarization of the online public through news articles and user comments from the Internet. The research includes topic modeling to measure the diversity of media reports, sentiment analysis to measure online public opinion, and interrupted time series analysis to understand how a particular event influences online attitudes. A combination of these methods is used to attempt to estimate the strength of political polarity in the online environment. The study shows diverse media reports by election region and candidate, where the online public repeatedly reveals high negative and low positive attitudes towards each candidate. Moreover, political polarity can differ based on the level of interest in an election. Although voters pay less attention to a by-election than a presidential election, there is a solid political polarity in the online world. Hence, the research recommends preparing measures to alleviate the polarization as politics requires significant online participation.

• Maritime Security
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• v.3 no.1
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• pp.211-235
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• 2021

As a result of the Falkland Islands War from April 2 to June 14, 1982, Britain overcame severe economic depression and reclaimed the glory of the former British Empire by winning the war. On the other hand, Argentina was greatly affected by the collapse of a military dictatorship and the birth of a democratic government. This study suggests strategies for responding to maritime disputes that may occur in Dokdo Island in the future by applying "DIME on PMESII" to the Falkland Islands dispute. In particular, the study analyzes how DIME (diplomacy, information, military, and economy) capabilities have an effect as a means of the total national power of a country that effectively controls the disputed territory. Based on the results of this study, the response strategies related to the Dokdo maritime dispute are as follows. First, effective control over the disputed territory should be effectively maintained and strengthened like in Britain. This strategy inspires patriotism, supports the government during warfare, secures a just cause for war, and gains international support. Second, 'DIME on PMESII' was effective in modern warfare by focusing our DIME capabilities on the weaknesses of the other country's PMESII system. That is, wars are not won simply by the conflict of armed forces but by a nation's overall national strength, such as diplomatic, information, and economic capabilities. Third, appropriate strategies for neighboring countries are needed to overcome the possibility of limited warfare in the sea through preparations for Dokdo maritime disputes in the future.

• Korean Journal of Agricultural and Forest Meteorology
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• v.24 no.1
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• pp.35-47
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• 2022

Expansion of potato production areas can improve the food security in North Korea because the given crop has less requirements for agricultural materials and facilities. The Global Agro-Ecological Zones (GAEZ) model, which was developed to evaluate climate suitability under different cultivation conditions, was used to identify potential areas for the potato production. The spatial estimates of crop suitability under low and high input management conditions were downloaded from the GAEZ data portal. The values of suitability were obtained at the potato occurrence sites retrieved from the Global Biodiversity Information Facility (GBIF) database. The suitable areas for the potato production were identified using a threshold value derived from the suitability estimates at the occurrence sites. It was found that 90% of the occurrence sites had the suitability index value >3,333, which was set to be the threshold value. The suitable areas in North Korea were summarized by province and county. Rice cultivation areas were excluded from the analysis. The reported relative acreage of potato production was better represented by the suitable areas under the low input management options than the high input conditions. The suitable areas also had a similar distribution to the reported acreage of potato production by county. These results indicated that the GAEZ model would be useful to identify the candidate production areas, which would facilitate the increases in potato production especially under future climate conditions. Furthermore, monthly maps of crop suitability can be used to design cropping systems that would improve crop production under the limited use of agricultural materials and facilities.

• The Journal of the Acoustical Society of Korea
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• v.41 no.5
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• pp.589-600
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• 2022

In order to verify the reliability of Dry Test Bench (DTB) used for testing the output energy from ballistic extracorporeal shock wave therapeutic devices, the measurements with DTB were compared with the acoustic energy measured with a Laser Doppler Vibrometer (LDV) for a commercial ballistic ESWT device. It was shown that the mechanical energy detected with DTB had variability maintained within 5 % at the same output power setting and also had a linear correlation (adj. R² = 0.991) with the acoustic energy measured with the LDV for the entire output power settings. Using the correlation between the two methods and the correlation on the acoustic energy measured in between air and water with the LDV, the DTB measurement can be used to estimate the energy flux density in water with an average error of 7.85 % for the entire output power settings of the ballistic shock wave generator considered in the experiment. DTB provides information limited to the output mechanical energy and therefore it is not suitable for testing the various acoustic output parameters required in IEC61846 and IEC63045. However, DTB that is simple in measurement principles and easy to use is expected for manufacturers and clinical users to monitor the performance of ballistic Extracorporeal Shock Wave Therapy (ESWT) devices.

• Journal of Naturopathy
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• v.11 no.2
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• pp.143-151
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• 2022

Background: The singing bowl is a bowl-shaped percussion instrument and is used in meditation and healing programs, but the mechanism of its clinical effects is unclear. Purpose: In this paper, we reviewed the peculiar acoustic property of the singing bowl sound and discussed on physical mechanisms of the clinical effects of the singing bowl sound. Methods: We studied the literature by reviewing it. Results: There are multiple pitches at adjacent frequencies in the singing bowl sound, and they give rise to the beat phenomenon. This results in a solid persisting beating felt in the singing bowl sound. Furthermore, the beat that depends on singing bowls and playing methods includes a rhythm often similar to the frequency band of brain waves (theta wave) observed in meditative states and induces a synchronization phenomenon in which the rhythm activates the brain waves in meditative states. Furthermore, we are to infer that the clinical effect of the singing bowl sound is closely associated with the synchronization of brain waves to the beat rhythm of the singing bowl sound. Conclusion: To clearly understand the clinical mechanism of the singing bowl sound, we suggest further systematic studies on the psychological and physiological responses to the beats of the singing bowl sound.