• Food Science and Preservation
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• v.31 no.2
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• pp.276-286
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• 2024

In the present study, we investigated whether a mixture of fucoidan and Crepidiastrum denticulatum extract (FCE) had the potential to improve the therapeutic efficacy of cancer treatment. The results demonstrated that FCE significantly reduced cell viability and induced the release of LDH (lactate dehydrogenase) and DNA fragmentation in HepG2 cells in a dose-dependent manner. In addition, FCE treatment also increased the protein expression level of p53, the release of cytochrome c, and the loss of mitochondrial membrane potential. Moreover, FCE dose-dependently increased protein expression levels of Bax, and cleaved caspase-3 and -9. However, FCE decreased the protein expression level of Bcl-2. These results suggest that FCE inhibits cell proliferation and induces apoptosis via the mitochondrial-mediated intrinsic pathway. The present study demonstrates that FCE can be used as an anti-cancer agent for liver cancer based on apoptosis mechanism.

• The Journal of the Convergence on Culture Technology
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• v.10 no.2
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• pp.493-498
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• 2024

With the rapid advancement of generative artificial intelligence technology, there is growing interest in how to utilize it in practical applications. Additionally, the importance of prompt engineering to generate results that meet user demands is being newly highlighted. Exploring the new possibilities of generative AI can hold significant value. This study aims to utilize ChatGPT 4.0, a leading generative AI, to propose an effective method for evaluating user experience through the analysis of online customer review data. The user experience evaluation method was based on the six-layer elements of user experience: 'functionality', 'reliability', 'usability', 'convenience', 'emotion', and 'significance'. For this study, a literature review was conducted to enhance the understanding of prompt engineering and to grasp the clear concept of the user experience hierarchy. Based on this, prompts were crafted, and experiments for the user experience evaluation method were carried out using the analysis of collected online customer review data. In this study, we reveal that when provided with accurate definitions and descriptions of the classification processes for user experience factors, ChatGPT demonstrated excellent performance in evaluating user experience. However, it was also found that due to time constraints, there were limitations in analyzing large volumes of data. By introducing and proposing a method to utilize ChatGPT 4.0 for user experience evaluation, we expect to contribute to the advancement of the UX field.

• Journal of the Korean Applied Science and Technology
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• v.40 no.6
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• pp.1567-1579
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• 2023

Sucralose is used as a sucrose alternative in the food sector and is a globally approved pyrogenic, high-intensity artificial sweetener. However, due to the lack of studies on the effects of sweeteners on the brain, this study confirmed whether short-term consumption of sucralose has cognitive and memory protective effects in scopolamine-induced memory-injured animal models. After oral administration of sucralose 2, 5, and 10 mg/kg, scopolamine (1 mg/kg) was administered to the control group and the drug group 30 minutes later, and saline was administered intraperitoneally to the normal group, followed by behavioral experiments As a result of the experiment, Y-Maze, passive avoidance, and Morris WaterMaze recovered more than 10% of cognitive function compared to the control group. In addition, as a result of measuring proinflammatory cytokines, sucralose was found to inhibit IL-6 and TNF-α by more than 30%, and we observed that the expression level of ERK-CREB with intracellular signaling mechanisms increased in a concentration-dependent manner. Therefore, it suggests that sucralose is associated with functional foods for the prevention of functional food patients.

• Journal of the Korean Society of Marine Environment & Safety
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• v.30 no.1
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• pp.97-107
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• 2024

Despite the rapid advancement in image recognition technology, achieving perfect digitization of tabular documents and handwritten documents still challenges. The purpose of this study is to improve the accuracy of digitizing the logbook by correcting errors by utilizing associated rules considered during logbook entries. Through this, it is expected to enhance the accuracy and reliability of data extracted from logbook through OCR programs. This model is to improve the accuracy of digitizing the logbook of the training ship "Saenuri" at the Mokpo Maritime University by correcting errors identified after Optical Character Recognition (OCR) program recognition. The model identified and corrected errors by utilizing associated rules considered during logbook entries. To evaluate the effect of model, the data before and after correction were divided by features, and comparisons were made between the same sailing number and the same feature. Using this model, approximately 10.6% of errors out of the total estimated error rate of about 11.8% were identified, and 56 out of 123 errors were corrected. A limitation of this study is that it only focuses on information from Dist.Run to Stand Course sections of the logbook, which contain navigational information. Future research will aim to correct more information from the logbook, including weather information, to overcome this limitation.

• Journal of the Korean Society of Marine Environment & Safety
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• v.30 no.1
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• pp.118-126
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• 2024

In this paper, the research contents and results related to the automation of the hull-form optimal design of container ships are summarized. A container ship is a ship that generally operates near Froude number of 0.26. To implement hull-form optimal design automation for ships operating at this speed, an optimization algorithm, a hull-form change algorithm, a ship performance prediction algorithm, an automation algorithm, and an iterative calculation technique were applied to develop a numerical analysis computer program that enables hull-form optimal design automation of the container ship, and it was named HOTCONTAINER. In this study, a sensitivity analysis algorithm was developed and applied to appropriately set design variables for hull-form optimal design. To understand the reliability and real ship applicability of the developed algorithm, a numerical analysis was performed on KCS(KRISO Container Ship), a container ship that has been studied in various ways worldwide. Consequently, the optimal ship was derived, and the wave resistance, wave pattern, and wave height of the target and optimal ship were compared. In conclusion, compared the target ship, the optimal ship a 47.63% decrease in wave resistance, and the displacement and wet surface area decreased by 0.50% and 0.39%, respectively.

• Journal of Applied Biological Chemistry
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• v.66
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• pp.197-203
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• 2023

Callus cultivation is a method for producing a large amount of tissue of a plant in the laboratory, regardless of the environment. Lycoris chejuensis, a plant species native to jeju island, is a member of the Lycoris family has been used as a traditional medicine for the treatment of diverse diseases. In this study, we evaluated anti-inflammatory effect of biorenovated Lycoris chejuensis callus (LCB) in lipopolysaccharide (LPS)-induced RAW264.7 cells. As a result, LCB was less toxic to the cells in the concentration range of 25, 50, and 100 ㎍/mL as shown by the improved viability of LCB treated cells than compared to Lycoris chejuensis callus (LC) treatment. In addition, LCB inhibited the generation of NO and prostaglandin E₂ through the suppression of inducible nitric oxide synthase and cyclooxygenase-2 protein expression. LCB also attenuated the expression of interleukin-1β, interleukin-6 and tumor necrosis factor-α induced by LPS. The results suggest that LCB has anti-inflammatory activity on the LPS-induced inflammatory response and may be suitable for the development of potent functional cosmetic material.

• Journal of the Korea Organic Resources Recycling Association
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• v.32 no.1
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• pp.39-47
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• 2024

In this study, LiDAR-detective black material is synthesized by recycling silicon sludge (SS) that is generated from semiconductor manufacturing process, and its recognition is confirmed using two types of LiDAR sensors (MEMS and Rotating LiDAR). In detail, metal impurities on the surface of SS is removed, followed by coating of titanium dioxide (TiO₂) and subsequent chemical reduction to obtain SS-derived black TiO₂ (SS/bTiO₂) material. As-prepared SS/bTiO₂ is mixed with transparent paint to prepare hydrophilic black paints and applied to a glass substrate using a spray gun. SS/bTiO₂-based paint shows similar blackness (L^*=15.7) compared to commercial carbon black-based paint, and remarkable NIR reflectance (26.5R%, 905nm). Furthermore, MEMS and Rotating LiDAR have successfully detected the SS/bTiO₂-based paint. This is attributed to the occurrence of high reflection of light at the interface between the black TiO₂ and the silicon sludge according to the Fresnel's reflection principle. Hence, the new application field to effectively recycle silicon sludge generated in the semiconductor manufacturing process has been presented.

• Korean Journal of Environmental Biology
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• v.41 no.4
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• pp.427-438
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• 2023

Biocide dichlofluanid breaks down quickly and accumulates easily in sediment, potentially causing a persistent impact on various marine organisms. We analyzed the potential toxicity of dichlofluanid on major aquaculture species in Korea, Undaria pinnatifida. Female gametophytes of U. pinnatifida were exposed to dichlofluanid at concentrations of 0, 1, 2, 4, 8, 16, and 32 mg L^-1, and their survival and relative growth rate were analyzed. The no observed effect concentration(NOEC), lowest observed effect concentration (LOEC), and median lethal concentration (LC₅₀) for female gametophyte survival were determined as 1, 2, and 10.82 (95% CI: 8.87-13.23) mg L^-1, respectively. The NOEC, LOEC, and median effective concentration (EC₅₀) for relative growth rate were 1, 2, and 6.58 (95% CI: 6.03-7.17) mg L^-1, respectively. Female gametophytes of U. pinnatifida were expected to experience toxic effects at concentrations above 2 mg L^-1 of dichlofluanid. These research findings are expected to serve as important reference data for evaluating the toxicity effects of U. pinnatifida in its early life stages when exposed to dichlofluanid.

• Journal of Korean Home Economics Education Association
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• v.35 no.4
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• pp.33-45
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• 2023

The purpose of this study is to investigate the association between dietary behavior and related factors according to the generalized anxiety disorder (GAD) in adolescents. The results of analyzing demographic characteristics according to the GAD showed that gender, age, BMI, type of school, residence type, father's nationality, smoking and drinking experience, perceived health status, perception of body shape, economic status, academic achievement, physical activity, sedentary time and smartphone usage time were related to the GAD (p<0.01). The results of analyzing dietary behavior according to the GAD showed that the frequency of water intake, sweetened beverage intake, fast food intake, fruit intake and breakfast intake were related to the GAD (p<0.001). The results of analyzing depression and suicidality according to the GAD showed that depression, suicidal ideation, planning, and attempts were all related to the GAD (p<0.001). Even after adjusting for factors corresponding to demographic characteristics, it was confirmed that the level of GAD had a significant effect on depression and suicidality. This study is significant in that it provided basic data on adolescent mental health problems by analyzing dietary behavior and related factors according to the level of GAD.

• Journal of Korean Home Economics Education Association
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• v.35 no.3
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• pp.1-20
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• 2023

In order to develop a picture book for desirable eating habits of young children, the contents of nutrition education in picture books were analyzed. A total of 128 picture books were analyzed: 42 picture books from the Nuri-curriculum teacher's guide (Nuri), 40 picture books recommended by the National Library for Children & Young Adults (NLCY), and 46 picture books published by the Center for Children's Food-service Management (CCFM). As a result of analysis of dietary guidelines for Koreans, the item that appeared most frequently in picture books was 'Consume a variety of foods every day' (28.91%). The second most common dietary guidelines in the picture books was 'Enjoy a diet that incorporates local ingredients and is environmentally conscious' (21.88%). As a result of examining the main goal of 'eating right' in the Nuri Curriculum, 'healthy food' accounted for 36.72% and 'eating a variety of food' accounted for 30.47%. 'Eating with the right attitude' 4.69%, 'valuing food' 3.13%, and 'dining etiquette' 6.25% were low. Therefore, it is necessary to develop and distribute picture books that reflect the contents that are insufficient.