• Title/Summary/Keyword: 무작위 실험연구

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Development of SNP Markers for Domestic Pork Traceability (국내산 돼지고기의 원산지 검증을 위한 SNP Marker Set 개발)

  • Kim, Sang-Wook;Li, Xiaoping;Lee, Yun-Mi;Kim, Jong-Joo;Kim, Tae-Hun;Choi, Bong-Hwan;Kim, Kwan-Suk
    • Journal of Animal Science and Technology
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    • v.52 no.2
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    • pp.91-96
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    • 2010
  • The purpose of the study was to develop an optimum SNP marker set to be utilized for domestic pork traceability. The study tested 51 SNP markers analyzed for origin of farm to be determined from genotypes of offspring and parents in pigs. With the simulation data through random mating population (PI), half sib mating population ($PI_{half-sib}$) and full sib mating population ($PI_{sibs}$), probability of identical genotypes were analyzed as $5.63{\times}10^{-33}$, $4.35{\times}10^{-15}$ and $1.32{\times}10^{-15}$, respectively. The 51 SNP markers also had 100% accuracy for parental determination. These results suggest that if the pig breeding stock is genotyped with the 51 SNP markers, the genotype information of individual offspring can be checked for farm origins by tracing parental sow and sire. Therefore, these SNP markers will be useful to trace the pork from production to consumption in pigs.

Botulinum Toxin type A injection Versus Lidocaine Injection for Myofascial Pain Involving upper Trapezius (승모근 근막동통에 대한 보툴리눔 독소와 리도카인 주사의 치료효과 비교)

  • Ahn, Sung-Woo;Park, Eun-Hee;Kim, Mee-Eun
    • Journal of Oral Medicine and Pain
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    • v.30 no.3
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    • pp.345-351
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    • 2005
  • The purpose of this double-blind study was to evaluate clinical effects of botulinum toxin type A (BTX-A) injection on myofascial pain syndrome (MPS) involving upper trapezius and compare with those of lidocaine injection. 21 patients presenting with active TrP1 and/or TrP2 in the upper trapezius over 6 months were selected for this study. The subjects were randomly divided into two groups; one group injected with BTX-A (15 unit of $Botox^{(R)}$ / 0.3 ml per trigger point (TrP)) and the other group injected with 0.5% lidocaine (0.3 ml /TrP). The clinical effects were evaluated by VAS and PPT at baseline, 2, 4, 6 and 8 weeks after treatment. BTX-A group showed persistent decrease of VAS values and increase of PPT values following treatment. While there was no significant difference in VAS values between BTX-A and lidocaine groups (p=0.347), there was significant difference in PPT values after treatment between two groups (p=0.000). The subjects received BTX-A showed noticeable improvement in PPT values after treatment, suggesting more reliable effect of BTX-A injection compared with lidocaine injection. The results of this study support that the direct injection of BTX-A to a TrP is an effective and safe treatment for MPS involving upper trapezius.

The Effects of Task-Oriented Circuit Training on The Upper Extremity Function and Quality of Life in Chronic Stroke Patients (유비쿼터스 의료환경에서 순환식 과제 지향적 훈련이 뇌졸중 환자의 상지 기능과 삶의 질에 미치는 영향)

  • Lee, Gue-Dong;Kim, Young-Hun;Moon, Jong-Hoon;Park, Kyung-Young
    • The Journal of the Korea institute of electronic communication sciences
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    • v.13 no.3
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    • pp.651-660
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    • 2018
  • The purpose of this study was to investigate the effects of task-oriented circuit training(: TOCT) on upper extremity function and quality of life in chronic stroke patients. 20 stroke patients were randomized and divided into 2 groups: a preservation therapy group and TOCT group. The intervention sessions were given five times a week for four weeks. The Stroke Impact Scale(: SIS), EuroQual-5Domains(: EQ-5D), Fugl-Myer Assessment(: FMA), Motor Activity Log(: MAL), Canadian Occupational Performance Measure(: COPM) were used to measure the upper extremity function and the quality of life. In results, Two groups improved in upper extremity function after the intervention(p<.05). The EQ-5D scores of TOCT group were a significantly higher than preservation group(p<.05). The Ironing, Folding towels, Hang out towels on drying rack in COPM scores in both of performance and satisfaction have improved more than preservation group(p<.05). In conclusion, the TOCT has significant helpful effect to chronic stroke patients. These findings can be used to chronic stroke patient as an intervention for upper extremity function and quality of life.

The Effect of the Fall Prevention Exercise Program Focussed on Strengthening of the Lower Extremity Muscles on the Change of Physical Function and Muscle Architecture of the Elderly (하지근력강화중심 낙상예방운동이 노인의 신체기능 및 근구조 변화에 미치는 영향)

  • Yang, Ji;Lee, Wan-Hee;Kang, Ki-Seon;Kim, Hyo-Sil
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.3
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    • pp.1904-1919
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    • 2015
  • This study was conducted to verify the effect of the fall prevention exercise program (FPEP). From 1st June to 14th July in 2014, 52 subjects above the age of 65 in 2 health clinics of A town, J city were randomly assigned to two groups(exercise 31, control 21). While exercise group performed FPEP twice a week for 6 weeks, control group received education only. The results showed significant difference between the two groups in the TUG of physical function(P=.032). There were no statistically significant difference between the two groups in the fear of falls, falls efficacy of mental functions. The result of ultrasound measurement of lower extremity muscles showed statistically significant differences between groups in the 7 items(RF CSA Contraction RF DIS Resting, TA Thickness Contraction, TA P-angle Contraction, GCM Thickness Resting, GCM Thickness Contraction, GCM P-angle Contraction)(p<.05). In conclusion, the FPEP is very effective in the prevention of falls.

The effects of the correction exercise program combined with stretching and elastic band exercise on femoral intercondylar distance, Q-angle, plantar pressure in undergraduate with genu varum (탄성밴드운동과 스트레칭을 이용한 교정운동프로그램이 내반슬 대학생들의 무릎간 간격, Q-각 및 족압의 변화에 미치는 영향)

  • Yu, Byong-Kyu;Kim, Eun-Hye
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.3
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    • pp.2064-2072
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    • 2015
  • The aim of this study is to identify the effects of the correction exercise program on femoral intercondylar distance, Q-angle and plantar pressure in undergraduate with genu varum. A experimental study with a randomized controlled trial design was used. Thirty subjects with genu varum were allocated in two groups: the experimental group (n=15) or the control group (n=15). The experimental group conducted correction exercise program for 30 minutes a day, 5 times a week, for 6 weeks, while the control group did not perform any exercise. The correction exercise program group showed a significant decreased femoral intercondylar distance, plantar pressure of M 4, M 5 (Metatarsal 4, 5). Also the correction exercise program group significantly increased Q-angle, plantar pressure of Toe 2-5 and M 1, M 2, M 3 (Metatarsal 1, 2, 3) (Rt, Lt) (p<.05). Thus, we suggested that the correction exercise program may be suitable intervention to improve normal alignment in undergraduate with genu varum.

Physiological Effects of Walking and Viewing on Human at a Urban Arboretums (도심 수목원에서의 경관감상과 산책이 인체의 생리적 안정에 미치는 영향)

  • Park, Bum-Jin;Ka, Jae-Nam;Lee, Min Sun;Kim, Seon-A;Park, Min-Woo;Choi, YoonHo;Joung, DaWou;Kwon, Chi-Weon;Yeom, Dong-Geol;Park, Soonjoo;Lee, Joon-Woo;Kim, Geonwoo
    • Journal of Korean Society of Forest Science
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    • v.103 no.4
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    • pp.664-669
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    • 2014
  • This research was conducted to investigate the impact of viewing scenery and walking in the urban forest on physiological relaxation of humans. The experiment was conducted in Hanbat Arboretum located in Daejeon, and the control experiment was conducted in front of Daejeon City Hall. The subjects that participated in the experiment comprised 24 Korean male university students in their 20s (average age, $21.1{\pm}2.5years$), participated in the experiment as the subject, and these subjects were classified into three groups divided into three locations such as the pine forest in Arboretum, the pond in Arboretum, and the city. The subjects sat down and viewed scenery for 10 min, and they then walked for 15 min. Further, physiological changes were measured using indicators such as heart rate variability (HRV), blood pressure, and pulse rate. As a result, when subjects viewed scenery and walked in the urban forest, a statistically significant increase in the high frequency (HF) power of HRV and decrease in systolic pressure was observed compared with when subjects viewed scenery and walked in the city. Through this research, it was found that activities like viewing scenery or walking in Arboretum of the city are effective in increasing the physiological relaxation of the city residents.

Effect of PNF Combination Patterns on Muscle Activity of the Lower Extremities and Gait Ability in Stroke Patients (PNF 결합패턴이 뇌졸중 환자의 하지 근 활성도 및 보행능력에 미치는 영향)

  • Jeong, Woo-Sik;Park, Seung-Kyu;Park, Jong-Hang;Lee, Hong-Gyun;Kim, Kyung-Yoon
    • The Journal of the Korea Contents Association
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    • v.12 no.1
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    • pp.318-328
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    • 2012
  • The purpose of present study was to determine effects of a PNF combination pattern training on muscle activity of lower extremities and gait ability in hemiparetic subjects. Twenty chronic stroke patients participated. Participants were randomly divided into either control group and experimental group. Experimental group received PNF combination pattern training, four times per a week for six weeks and control group received general exercise training. For the lower limbs muscle activity, RMS of action potential were analyzed and gait ability tests was conducted with 10MWT, DGI and F8WT. For the significance test of control and experimental group for measuring time by exercise application method, two-way repeated measure ANOVA. As the result, muscle activity of RF(p<.05), VM, TA, LH, LG was significantly increased between measurement period(p<.001), In VM, TA, LH, LG, there were interactions each measurement time and between group. 10MWT, DGI, F8WT in gait ability was significantly improved between measurement periods(p<.001) and In 10MWT, DGI, F8W, there were interaction each measurement time and between group. In conclusion, the PNF combination pattern application will be effective strategy to increasing the muscle activity and improving gait ability in the rehabilitation of stroke patients.

Effects of High Polyunsaturated Fat Diet on Human Plasma Cholesterol Esterification and Transfer (고 불포화 지방산 식이가 인체 혈청 Cholesterol의 Esterification과 Transfer에 미치는 영향)

  • Lee Myoung Sook
    • Journal of Nutrition and Health
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    • v.26 no.7
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    • pp.819-828
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    • 1993
  • The reaction of lecithin cholesterol acyltransferase(LCAT) and cholesteryl ester transfer protein (CETP) are important in cholesterol esterification and transfer for the reverse cholesterol transport(RCT) system. The purpose of this study were to assess the effects of fatty acid unsaturation on RCT system. After 12 female human subjects consumed a prescribed high saturated fat diet prior to the period, two groups of six subjects were provided with a high PUFA(corn oil) or a high SFA(butter) as major fats in a 40 en % fat diet. Butter feeding increased plasma total-(34%), esterified-(96%), HDL_3$-(23%), LDL-(20%), and VLDL plus LDL(35%) cholesterol while corn oil feeding decreased esterified-(25%), LDL(15%) cholesterol and TG(27%). There were significant differences of fats on total-(p=0.0001), esterified-(p=0.0001), total HDL-(p=0.005), $HDL_2$-(p=0.01)and LDL-(p=0.0001) cholesterol. LCAT activity did not change during the period but highly correlated to apo A-I in HDL which was increased in the corn oil group. The 2.5 fold increased CETP activity in the butter group during the period might be related to changes in plasma VLDL plus LDL cholesterol level which were increased in the butter group.

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Effects of Laughter Therapy on Joint Pain, Functional Status of Knee Joint and Depression in Elderly with Degenerative Knee Arthritis (웃음요법이 퇴행성 슬관절염 노인의 관절통증, 관절기능상태, 우울에 미치는 효과)

  • Lee, Yim Sun;Park, Hyo Jung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.9
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    • pp.440-449
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    • 2020
  • This study examined the effects of laughter therapy in the elderly with degenerative arthritis who had joint pain, joint dysfunction, and depression. Through a single-blind, randomized assignment, an experimental group of 26 subjects and a control group of 26 subjects were recruited among the elderly with degenerative knee arthritis, who were over 65 years of age. From January 8 to March 11 of 2019, a total of 16 laughter therapies were administered two times a week, 60 minutes per session, in eight weeks. The pain threshold (p=.012) and joint function status (p<.001), which represents the pain, joint stiffness, and physical function, and depression (p<.001), in the experimental group improved after the eight weeks laughter therapy compared to the control group. Laughter therapy is a therapeutic intervention that can be delivered through physical or intellectual activities. This therapy is a non-invasive procedure and has the advantage that nurses can practice easily with a little training. It can be used as an intervention within community and clinical settings to relieve pain and improve depression in the elderly with arthritis.

Effect of Backward Walking Training on Balance Capability and Gait Performance in Patients With Stroke (후방보행 훈련이 뇌졸중 환자의 균형능력 및 보행에 미치는 영향)

  • Choi, Hyun-Suk;Jeon, Seon-Bok
    • Journal of Digital Convergence
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    • v.13 no.1
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    • pp.367-373
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    • 2015
  • The purpose of this study was to examine the effect of backward walking training on the balance capability(Functional Gait Assessment; FGA, Timed Up & Go Test; TUG) and gait performance(10 meter Walking Test; 10 mWT) of stroke patients. Eighteen with stroke patients were randomly allocated to an experimental and contral group of nine patients each. both groups received general neurorehabilitative physical therapy for 45 minutes per day 5 times per week during 4 weeks. The experimental group also performed additional backward walking training for 20 minutes per day 3 times per week during 4 weeks. There were signicantly increase by backward walking training in outcome of the balance capability from the FGA was increase from $17.67{\pm}1.00scores$ to $19.22{\pm}1.00scores$(p<.05), TUG was decrease from $26.45{\pm}1.37sec$ to $23.28{\pm}1.35sec$(p<.05) and 10 mWT was decreased from $21.74{\pm}1.35sec$ to $18.33{\pm}1.10sec$ (p<.05). These result suggest that backward walking training for stroke patients is effective in improving balance capability(FGA, TUG) and gait performance(10 mWT).