• Korean Journal of Applied Biomechanics
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• v.19 no.2
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• pp.257-264
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• 2009

The purpose of this study was to investigate the lower extremity kinematics and muscle activities of adductor longus(AL), gluteus medius(GME), gluteus maximus(GMA), biceps femoris(BF), rectus femoris(RF), gastrocnemius(GA), and tibialis anterior(TA) using three dimensional and Noraxon 8 channels EMG system during turn 0, 60, 90 and 120 degrees in patients with Parkinson's disease. Seven parkinson's patients and five healthy subjects were participated in the study. Participants with Parkinson's disease demonstrated significant differences in reduction of stride length and stride width. Also, they showed ill difference in muscle activities. The strength and balance of the lower extremity muscles may help to improve cutting movement and to prevent falling in parkinson's patients.

• Journal of Korean Ophthalmic Optics Society
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• v.5 no.2
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• pp.65-72
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• 2000

The study investigated the effects of base curve radius art the fit of thin, mid-water contact lenses. It was found that central corneal curvature(as measured with the keratometer) was not predictive of the best fitting base curve. Proper lens fit may be the single most important factor that ultimately determines the success of contact lens wear. Comfort, vision, and physiological response are all dependent on the fit of the lens. The percent of optimal fits was highest with the 8.4 mm base curve lens for all three ranges of keratometry values. When fit with the 8.4 mm lens. For most eyes, fitting a flatter lens led to greater decentration, decreased comfort, and no increase in lens movement. The 8.4 mm lens was found to provide on "optimal" fit in over 60% of eyes tested and a fit of "good" or "better" in nearly 90% of eyes tested. Comparisons of different manufactures' lens found that similiar lenses do not always fit in the same way due to subtle design and production differences. Therefore, different products may require different base curve radii to fit the same patient. This is even true when water content, center thickness, and diameter are approximately the same. A praditioner fitting a new patient in this lenses should begin with the 8.4 mm base curve radius.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.22 no.6
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• pp.587-596
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• 2009

The fiber bridging model is the crucial factor to predict or analyze the tensile behavior of fiber reinforced cementitious composites. This paper presents the fiber bridging constitutive law considering the distribution of fiber inclined angle and the number of fibers in engineered cementitious composites. The distribution of fiber inclined angle and the number of fibers are measured and analyzed by the image processing technique. The fiber distribution are considerably different from those obtained by assuming two- or three-dimensional random distributions for the fiber inclined angle. The simulation of the uniaxial tension behavior was performed considering the distribution of fiber inclined angle and number of fibers measured by the sectional image analysis. The simulation results exhibit multiple cracking and strain hardening behavior that correspond well with test results.

• Journal of the Korea Institute of Military Science and Technology
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• v.5 no.1
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• pp.83-95
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• 2002

Thermal conductivity of ceramic fibrous insulator was analysed and predicted by using the modeling/simulation technique. Ceramic fibrous insulators are widely used as high temperature insulator on account of their lightweight mass and heat resisting properties. Especially it is suitable to protect the high speed aircraft and missiles from severe aero-thermodynamic heating. Thermal conductivity of ceramic fibrous insulator could be determined from the conductive heat transfer and the radiative heat transfer through the insulator. In order to estimate conductive thermal conductivity, homogenization technique was applied, while radiative thermal conductivity was computed by means of random number and radiation probability. Particularly radiation probability can make it possible to estimate the conductivity of fibrous insulator without any experimental constant. The calculated conductivity predicted in the present study have a reasonable accuracy with an average error of 7 percent to experimental data.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.4
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• pp.612-623
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• 2022

Estimation of the presence of people in real time is extremely useful for businesses in providing better services. Many companies and researchers have attempted various researches in order to count the number of floating population in a specific space. Recently, as part of smart cities and digital twins, commercialization of measuring floating populations using Wi-Fi signals has become active in the public and private sectors. In this paper we present a method of estimating the floating population based on MAC-address values collected from smartphones. By distinguishing Real MAC-address and Random MAC-address values, we compare the estimated number of smartphone devices and the actual number of people caught on CCTV screens to evaluate the accuracy of the proposed method. And it appeared to have a similar correlation between the two datas. As a result, we present a method of estimating the floating population based on analyzing Wi-Fi Probe Requests.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.4
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• pp.113-120
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• 2022

Purpose : Lymphedema is a common complication in mastectomy patients and is usually characterized by pain, swelling, and limited range of motion (ROM) in the arm. Electromyostimulation (EMS) is widely used for the rehabilitation and recovery of subjects with various neuromusculoskeletal disorders after breast cancer. However, EMS has not yet been used in many Pilates exercises. This study was aimed at comparing the effects of instrument Pilates integrated with EMS on pain, lymphedema, and ROM of the upper extremity (UE) in breast cancer subjects after mastectomy. Methods : Nine female breast cancer subjects who had undergone mastectomy participated in the study. The subjects underwent instrument Pilates with EMS (experimental group) or instrument Pilates only (control group). Pain, lymphedema, and ROM of the UE were measured using the visual analog scale (VAS), the circumference length of the UE, and the ROM of the UE. The Wilcoxon signed-rank test was used to compare the pain, lymphedema, and ROM of the arm before and after the intervention, and the Mann-Whitney U test was used to compare the two groups. The statistical significance level was set to p < .05. Results : In the experimental group, there were significant differences in pain (p<.05) and UE circumference (p<.05) before and after intervention. However, there was no significant difference between the two groups in VAS (p>.05) or circumference length of the UE (p>.05). There was one significant difference between the groups in terms of internal rotation of the ROM of the UE (p<.05). Conclusion : These results show that instrument Pilates exercises combined with EMS may positively affect the internal rotation of the ROM of the UE in breast cancer patients after mastectomy, thus contributing to existing knowledge about instrument Pilates using EMS for the effective management of in breast cancer subjects after mastectomy.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.33 no.2
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• pp.175-182
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• 2023

Differential cryptanalysis is one of the analysis techniques for block ciphers, and uses the property that the output difference with respect to the input difference exists with a high probability. If random data and differential data can be distinguished, data complexity for differential cryptanalysis can be reduced. For this, many studies on deep learning-based neural distinguisher have been conducted. In this paper, a deep learning-based neural distinguisher for PIPO 64/128 is proposed. As a result of experiments with various input differences, the 3-round neural distinguisher for the differential characteristics for 0, 1, 3, and 5-rounds achieved accuracies of 0.71, 0.64, 0.62, and 0.64, respectively. This work allows distinguishing attacks for up to 8 rounds when used with the classical distinguisher. Therefore, scalability was achieved by finding a distinguisher that could handle the differential of each round. To improve performance, we plan to apply various neural network structures to construct an optimal neural network, and implement a neural distinguisher that can use related key differential or process multiple input differences simultaneously.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.24 no.1
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• pp.83-88
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• 2024

In this research, we propose a Semi-Supervised learning based railroad surface defect detection method. The Resnet50 model, pretrained on ImageNet, was employed for the training. Data without labels are randomly selected, and then labeled to train the ResNet50 model. The trained model is used to predict the results of the remaining unlabeled training data. The predicted values exceeding a certain threshold are selected, sorted in descending order, and added to the training data. Pseudo-labeling is performed based on the class with the highest probability during this process. An experiment was conducted to assess the overall class classification performance based on the initial number of labeled data. The results showed an accuracy of 98% at best with less than 10% labeled training data compared to the overall training data.

• The Journal of Bigdata
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• v.9 no.1
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• pp.141-152
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• 2024

In the biopharmaceutical contract manufacturing organization (CMO) business, establishing a production schedule that satisfies the due date for various customer orders is crucial for competitiveness. In a CMO process, each order consists of multiple batches that can be allocated to multiple production lines in small batch units for parallel production. This study proposes a meta-heuristic algorithm to establish a scheduling plan that minimizes the total delivery delay of orders in a CMO process with identical parallel machine. Inspired by biological evolution, the proposed algorithm generates random data structures similar to chromosomes to solve specific problems and effectively explores various solutions through operations such as crossover and mutation. Based on real-world data provided by a domestic CMO company, computer experiments were conducted to verify that the proposed algorithm produces superior scheduling plans compared to expert algorithms used by the company and commercial optimization packages, within a reasonable computation time.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.11a
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• pp.27-30
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• 1994

잠재적으로 항감염 약제로 사용될 가능성이 있는 약제들의 초기 연구과정에서 주된 관심사는 이들이 미생물(세균, 바이러스, 기타 기생충)에 대한 작용들이 있는가 하는 점이다. 이러한 작용들이 실험적으로 충분히 연구가 된 후에야 실험동물에서 그 효과를 연구한다. 항 바이러스 제제의 경우에는 세포배양을 통한 연구가 그 약제의 독성과 효용성을 나타내는데 필수적인 것이 된다. 여러 종류의 동물을 이용한 생체실험에서 약제의 일반적인 흡수와 배설, 분포 등에 관한 정보와 약제 자체와 동물 내에서의 대사적 변화에 대한 정보가 제공된다. 여러 가지 미생물로 감염을 시킨 적합한 동물과 여러 가지 용량으로 치료하는 실험을 통하여 약제의 항 감염 능력이 알려지게 된다. 동물에서의 생체실험과 실험관내에서 실험을 하고 나서야 사람에서의 연구가 이루어지게 된다. 소위 전임상시험에서 대표적 병원성 미생물에 대한 생물학적효과, 약리학적 효과와 독성 그리고 동물실험모델에서의 가능한 효과가 결정된 후에 임상시험에 들어가기 마련이다. 항균제의 임상시험에는 각각의 감염질환에 대한 진단 및 치료기준을 반영하는 것이 기본이다. 새로운 항균제의 임상시험에서는 안전성과 효과가 반드시 밝혀져야 한다. 1상에서는 인체에서의 약리효과, 안전성이 주목적이며, 2상과 3상은 겹쳐지는 점도 있으나 하나 또는 그 이상의 적응증에 대한 항균제의 효과와 단기간의 부작용은 2상에서 관찰하여야하며, 다수의 환자에서 제안된 적응질환의 무작위임상시험과 다수에서의 안전성도 3상에서 관찰하여야 한다. 4상에서는 이상에서의 자료로 시판된 후에도 계속해서 감시하는 것으로 지속적으로 안전성을 관찰하는 것이다. 이러한 기본사항외에도 소아, 임산부, 고령자등에서의 임상시험도 넓은 의미에서 포함되어야 할 것이며 또한 질적인 면에서 조절하는 Quality Assurance도 중요하다.양상은 세 용량군 간 차이가 없었으나, 시험기에서 발열의 발현율이 낮았으며, 발열일 수와 항생제 사용일 수가 짧았다. 결론: 골수억제 조절 효과는 용량에 따른 혈액소견에 미치는 영향, 부작용, 감염의 빈도, 감염발생에 따른 항생제 사용기간 등을 고려하여 그 임상 유효성 평가시, 제 3상 시험에 사용할 권장량 (recommended dose) 은 250 ug/$m^2$/d $\times$ 10d 으로 관찰되었다.5주에 부검한 랫드의 간에서 c-myc 종양단백의 발현은 모든 처리군들이 대조군에 비하여 높게 발현되는. 것이 관찰되었으나 시험개시후 26주에 부검한 랫드의 간에서 c-myc 종양단백의 발현은 대조군에 비하여 차이가 거의 없었다. 따라서 랫드에서 화학적으로 유도한 간암발생 과정에서 NK 세포활성이 현저하게 억제되는 것으로 생각되며, c-myc 종양단백의 발현은 시험개시후 15주에 그 발현이 확실한 것으로 사료되어 진다.에 영향을 주는 성분이 있음을 제시하였다.1과 항우울약들의 항혈소판작용은 PKC-기질인 41-43 kD와 20 kD의 인산화를 억제함에 기인되는 것으로 사료된다.다. 것으로 사료된다.다.바와 같이 MCl에서 작은 Dv 값을 갖는데, 이것은 CdCl$_{4}$$^{2-}$ 착이온을 형성하거나 ZnCl$_{4}$$^{2-}$ , ZnCl$_{3}$$^{-}$같은 이온과 MgCl$^{+}$, MgCl$_{2}$같은 이온종을 형성하기 때문인것 같다. 한편 어떠한 용리액에서던지 NH$_{4}$$^{+}$의 경우 Dv값이 제일 작았다. 바. 본 연구의 목적중의 하나인 인체유