• Journal of Veterinary Clinics
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• v.31 no.5
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• pp.394-402
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• 2014

The objective of this study was to investigate the effect of chronic unpredictable stress on the reproductive function and ovarian luteinizing hormone receptor (LHR) expression. 9-week-old C57BL/6 female mice were randomly divided into two groups: control group and stressed group. Mice have been stressed twice a day for 35 days with 12 different stressors which were randomly selected. The results demonstrate that there is significant increase in the anxiety-related behaviors (P < 0.05), decrease body weight gain rate (P < 0.01) and decrease in the average of litter size in stressed mice compared with control group (P < 0.01). Furthermore, the rate of primary, secondary and early antral follicles in stressed mice significantly decreased (P < 0.05), whereas that of atretic follicles significantly increased compared with control mice (P < 0.01). The immunohistochemical analysis revealed that reduced LHR expression in granulosa cells of follicle and luteal cells of corpus luteum in response to chronic unpredictable stress. The western blot analysis revealed significantly decrease in LHR expression in the stressed mice ovaries compared with the control (P < 0.05). These results suggest that ovarian LHR expression affected by chronic unpredictable stress and the modulated ovarian LHR is responsible for ovarian follicular maldevelopment and reproductive dysfunction.

• Therapeutic Science for Rehabilitation
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• v.11 no.4
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• pp.85-97
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• 2022

Purpose : This study aimed to investigate the effects of a digital pegboard training program with visual and auditory feedback on hand function and visual perception in stroke patients. Methods : Twenty two participants were randomly assigned to an experimental or control group. The experimental group received training using a digital pegboard training program with visual and auditory feedback (n=11), while traditional occupational therapy was administered to the control group (n=11). Hand function was assessed before and after the intervention using the Nine-Hole Peg Test and manual function test (MFT), while visual perception was assessed using the Motor-Free Visual Perception Test-3rd edition (MVPT-3). Results : Following the intervention, both the experimental and control groups showed significant improvements in performance in the Nine-Hole Peg Test and MVPT-3 (p<.05). The improvement on both tests was significantly greater in the experimental group than in the control group (p<.05). Conclusion : The results suggest that digital pegboard training with visual and auditory feedback may improve hand function and visual perception in stroke patients. Therefore, this intervention can be effective in occupational therapy to aid the recovery of stroke patients.

• The Journal of Korean Academy of Prosthodontics
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• v.49 no.2
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• pp.138-144
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• 2011

Purpose: The purpose of this study was to evaluate the cleansing effect of recently developed alkaline ionized water, e-WASH, on microorganisms of the denture surface. Materials and methods: Removable partial and complete dentures were randomly assigned to the experimental group of 41 dentures, and the control group of 26. The denture was immersed in the e-WASH solution (experimental group), or tap water (control group) for 5 minutes. The plaque was collected from the denture surface before and after immersion, and smeared on the slide glass. Amount and motility of microorganisms were compared according to the morphology and strain of microorganisms, using the phase contrast microscope. Statistical analysis was accomplished with paired t-test and independent t-test at 95% confidence level (P<.05). Results: 1. The amount of cocci, bacilli, filamentous, spiral/comma, and the motility of bacilli, filamentous, and spiral/comma were decreased after denture cleansing with the alkaline ionized water, e-WASH (P<.05). But in the control group, only the amount of cocci showed a significant difference (P<.05), but no difference from the others. There were no differences in other analysis. 2. In the experimental group, the amount of cocci, bacilli, filamentous, spiral/comma, and the motility of bacilli, filamentous, and spiral/comma were smaller and more inactive compared to the control group (P<.05). Conclusion: These results indicated that the alkaline ionized water, e-WASH could effectively reduce the amount and motility of the experimented microorganisms on the denture surface, and that e-WASH could be recommended as an effective denture cleanser.

• Journal of Digital Convergence
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• v.11 no.8
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• pp.243-250
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• 2013

The present study is to determine the effect of lumbosacral stabilization exercise program on back pain disorder and gait velocity of patients with chronic low back pain. The subject was extracted randomly from 34 patients with chronic low back pain and divided into 18 patients of experimental group and 16 patients of control group. Before the experiment, the Oswestry disability index examination and analysis of gait speed were performed. Then, a conventional interventional therapy of physiotherapy was performed with the experimental group along with the lumbosacral stabilization exercise while only the conventional interventional therapy was done to the control group. Both groups did the above treatment every 30 minutes, four times a week for four weeks. Then, post-examination was carried out followed by comparing the back pain disorder index and gait velocity before and after the experiment for the two groups. The back pain disorder index showed that both experimental and control groups had significant difference within the group (p>.01)(p>.05), With regard to the gait velocity, both experimental and control groups had a significant difference within the experimental group and between the groups (p>.001)(p>.05).

• The Journal of Pediatrics of Korean Medicine
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• v.15 no.1
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• pp.255-259
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• 2001

본 연구는 운비요법(運脾療法)이 脾虛 동물모델 Rat의 흡수기능에 미치는 영향을 관찰하기 위한 것이다. 이혈평(利血平)으로 Rat의 비허(脾虛) 상태를 유발시킨 다음 최초로 비허(脾虛) 상태에서의 혈청 중 Zn 및 소장검막의 구조변화를 관찰하였고, 임상적으로는 소아의 편식증, 영양실조성 빈혈, 반복적인 소아감염증상(RRI) 등에 대한 운비법(運脾法)의 효과를 관찰하였다. 청결상태로 관리한 체중이 220-240g의 Wester계 웅성 Rat 15마리를 무작위로 각 5마리씩 정상군, 비허군(脾虛群), 중약투여군에 배분하여 3group으로 나누었다. 비허군과 중약투여군에는 모두 이혈평(利血平)을 소량으로 서서히 투여하였고, 중약투여군에는 동시에 중약 시럽(당장(糖漿))을 경구투여시켜 3주간 실험관찰하였다. 결과 : (1) 섭취량(g/일/마리) : 정상군은 22.1, 비허군(脾虛群)은 9.04, 중약투여군은 17.3으로 각각 나타났다. (2) 체중(g) : 정산군은 $284.2{\pm}32.51$, 비허군(脾虛群)은 $193{\pm}15.26$, 중약투여군은 $231.8{\pm}22.76$으로 각각 측정되었다. (3) 혈청 중 Zn함량(ug/1) : 정상군 $1911{\pm}993.8$, 비허군(脾虛群) $1094{\pm}249.4$, 중약투여군 $2599.8{\pm}1282.1$로 각각 측정되었다. 이와 같은 결과에서 중약투여군의 섭취량, 체중 및 혈청 중 Zn의 함량 모두 대조군에 비교하여 현저하게 개선되었음을 알 수 있다. (4) 소장의 정막구조 : 비허군(脾虛群)은 정상군에 비해 소장의 점막이 현저하게 얇고 융모상 돌기가 오그라들며 퇴화되는 변화를 나타냈고, 일부 융모상 돌기 끝의 상피세포는 국소적 괴사 및 퇴행성 변화를 일으키기도 하였다. 중약투여군은 이에 비해 소장점막이 거의 정상에 가깝게 회복되었다. 결론 : 운비요법(運脾療法)은 비허(脾虛) 동물모델에 대한 흡수기능의 개선에 효과가 있음을 본 실험에서 입증할 수 있었다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.7
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• pp.3088-3095
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• 2011

The purpose of this study was to investigate the effects of Pilates exercises on the improvement of blood pressure and respiratory function. 36 subjects which were randomly divided into Pilates exercises group(n=18) and control group(n=18). Subjects in the Pilates exercises group were regularly participated in Pilates exercise program for 8 weeks. We were measured the blood pressure and respiratory function such as blood pressure, VO2max, METs, and Anaerobic threshold at before and after the experiment. After 8 weeks, in Pilate exercises group, there were significant improvement on blood pressure and respiratory function except the diastolic blood pressure. And subjects participated in Pilates exercise group were significantly improved compared to control group on systolic blood pressure, VO2max, METs, and Anaerobic threshold. But in control group, there were no significant differences. In conclusion, regular participation in Pilates exercises improved the blood pressure and respiratory function. These results suggest that Pilates exercise is the method that replace aerobic exercise.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.8
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• pp.348-358
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• 2020

The purpose of this study was to examine the effects of auricular acupressure in patients with type 2 diabetes mellitus. Data collection was conducted from March 16 to May 11, 2018. A total of 44 participants with type 2 diabetes were recruited from welfare facilities. Participants in the experimental group (n=22) and placebo control group (n=22) received auricular acupressure on diabetes-related points (shenmen, pancreas, appetite control point, thirst point, and master endocrine point) and diabetes-unrelated points. The intervention was implemented on 5 consecutive days per week for a total of 6 weeks. To examine the effects of treatment, postprandial glucose, glycated hemoglobin, and blood lipid levels were evaluated. Postprandial glucose levels in the experimental group exhibited significant reduction over time compared to those in the placebo control group (p=.030). Glycated hemoglobin levels in the experimental group decreased significantly (t=-2.44, p=.024). However, there were no significant differences in blood lipid levels between the two groups. This study demonstrates that auricular acupressure on diabetes-related points for 6 weeks was highly effective in decreasing blood glucose levels in patients with type 2 diabetes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.5
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• pp.2240-2250
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• 2012

This study was to identify treatment effects of the shoulder control and strengthening exercise, on the subjects with secondary shoulder impingement syndrome at postmastectomy. The subjects were patients who visited our hospital due to secondary shoulder impingement syndrome(1-2 stage) at postmastectomy and they randomly allocated to two groups: a shoulder control and strengthening group (n=10) and a conservative therapy group (n=10). Both groups received conservative therapy for 5 sessions (40 minutes per week) for 4week. The shoulder control and strengthening exercises group practiced additional motor control and strengthening exercises for 60 minutes. Values of handgrip strength, pain(visual analog scale), upper extremity circumference, Disabilities of the Arm, Shoulder and Hand questionnaire, range of motion were compared with those of the conservative therapy group. There were significant differences in the amount of change of the range of motion and Disabilities of the Arm, Shoulder and Hand scale between the two groups (p<.05), however as a measure of handgrip strength, pain(visual analog scale), upper extremity circumference did not show a significant differences. These results suggest that a motor control and strengthening exercise program is feasible, secure and suitable for secondary shoulder impingement syndrome at postmastectomy.

• Journal of Convergence for Information Technology
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• v.9 no.10
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• pp.234-243
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• 2019

This study was conducted to investigate the effects of whole body vibration stimulation training combined with respiratory resistance on respiratory and balance function in stroke patients. 17 patients with chronic stroke were randomly assigned to the experimental group (n = 8) and the general vibration exercise program (n = 9). The intervention was conducted three times a week for 30 minutes once a week for 4 weeks. The respiratory function and balance ability were evaluated before and after the intervention to evaluate the degree of functional improvement. As a result, there was a significant difference (p<.05) between the respiratory function and the balance ability in the experimental group, and a significant difference(p<.05) in the respiratory function between the experimental group and the control group. The balance ability was not significantly different among the experimental groups. Through the results of this study, whole body vibration stimulation training combined with respiratory resistance may be useful as a program for improving respiratory function and balance ability of stroke patients.

• Journal of Naturopathy
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• v.10 no.1
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• pp.1-9
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• 2021

Purpose: This study has proved the intervention effects of the proposed logotherapy-based music imagery (LBMI) program on the self-worth of the personal assistants for the disabled. The program, in the image activities and at the stage of postlude after listening to music, unites logodrama of logotherapy, paradoxical intention and dereflected techniques. The intervention effects of the LBMI program were tested for the 28 personal assistants for the disabled who found themselves without the value and meaning of life and were randomly equally divided into the experimental and control groups. This intervention was carried out for the six different terms, each of which was alloted 60 minutes. To evaluate the intervention effects, the self-worth scale were examined before and after the intervention for both experimental and control group. The result shows that the self-worth improved significantly in the experimental group(p < 0.001), whereas it remained unchanged in the control group(p > 0.459). This finding proves that the proposed LBMI program ameliorates the self-worth of the personal assistants for the disabled.