• Title/Summary/Keyword: 무작위 대조군 실험연구

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Cleansing effect of the alkaline ionized water on microorganisms of the denture surface (알칼리 이온수의 의치 미생물에 대한 세정효과에 관한 연구)

  • Kim, Young-Mi;Choi, Yu-Sung;Cho, In-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.49 no.2
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    • pp.138-144
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    • 2011
  • Purpose: The purpose of this study was to evaluate the cleansing effect of recently developed alkaline ionized water, e-WASH, on microorganisms of the denture surface. Materials and methods: Removable partial and complete dentures were randomly assigned to the experimental group of 41 dentures, and the control group of 26. The denture was immersed in the e-WASH solution (experimental group), or tap water (control group) for 5 minutes. The plaque was collected from the denture surface before and after immersion, and smeared on the slide glass. Amount and motility of microorganisms were compared according to the morphology and strain of microorganisms, using the phase contrast microscope. Statistical analysis was accomplished with paired t-test and independent t-test at 95% confidence level (P<.05). Results: 1. The amount of cocci, bacilli, filamentous, spiral/comma, and the motility of bacilli, filamentous, and spiral/comma were decreased after denture cleansing with the alkaline ionized water, e-WASH (P<.05). But in the control group, only the amount of cocci showed a significant difference (P<.05), but no difference from the others. There were no differences in other analysis. 2. In the experimental group, the amount of cocci, bacilli, filamentous, spiral/comma, and the motility of bacilli, filamentous, and spiral/comma were smaller and more inactive compared to the control group (P<.05). Conclusion: These results indicated that the alkaline ionized water, e-WASH could effectively reduce the amount and motility of the experimented microorganisms on the denture surface, and that e-WASH could be recommended as an effective denture cleanser.

The Effects of Unpredictable Stress on the LHR Expression and Reproductive Functions in Mouse Models (실험적 마우스 모델에서 예측 불가능한 스트레스가 황체형성호르몬 수용체의 발현과 생식기능에 미치는 영향에 관한 연구)

  • Choi, Sung-Young;Park, Jin-Heum;Zhu, Yuxia;Kim, Young-Jong;Park, Jae-Ok;Moon, Changjong;Shin, Taekyun;Ahn, Meejung;Kim, Suk-Soo;Park, Young-Sik;Chae, Hyung-Bok;Kim, Tae-Kyun;Kim, Seung-Joon
    • Journal of Veterinary Clinics
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    • v.31 no.5
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    • pp.394-402
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    • 2014
  • The objective of this study was to investigate the effect of chronic unpredictable stress on the reproductive function and ovarian luteinizing hormone receptor (LHR) expression. 9-week-old C57BL/6 female mice were randomly divided into two groups: control group and stressed group. Mice have been stressed twice a day for 35 days with 12 different stressors which were randomly selected. The results demonstrate that there is significant increase in the anxiety-related behaviors (P < 0.05), decrease body weight gain rate (P < 0.01) and decrease in the average of litter size in stressed mice compared with control group (P < 0.01). Furthermore, the rate of primary, secondary and early antral follicles in stressed mice significantly decreased (P < 0.05), whereas that of atretic follicles significantly increased compared with control mice (P < 0.01). The immunohistochemical analysis revealed that reduced LHR expression in granulosa cells of follicle and luteal cells of corpus luteum in response to chronic unpredictable stress. The western blot analysis revealed significantly decrease in LHR expression in the stressed mice ovaries compared with the control (P < 0.05). These results suggest that ovarian LHR expression affected by chronic unpredictable stress and the modulated ovarian LHR is responsible for ovarian follicular maldevelopment and reproductive dysfunction.

PREVENTIVE EFFECT OF ADHESIVE TAPE SUPPLEMENTED WITH NaF ON ENAMEL EROSION IN VITRO (불소함유 접착테잎의 법랑질 침식 예방효과)

  • Lee, Sang-Ho;Lee, Nan-Young;Lee, In-Hwa
    • Journal of the korean academy of Pediatric Dentistry
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    • v.37 no.1
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    • pp.82-90
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    • 2010
  • This study examined the effect of adhesive tape supplemented with sodium fluoride on the prevention of dental erosion in vitro. Sound bovine tooth samples were selected and divided randomly into the following 4 groups according to the material treatments: group 1, APF gel; group 2, fluoride varnish; and groups 3 and 4, fluoride tape supplemented with 5% NaF in either a methyl cellulose or poly vinyl acetate carrier, respectively. All specimens were submitted to alternate cycles of acid exposure in a cola beverage (pH 4.3) and artificial saliva for $6\;{\times}\;5\;min/day$ over a 5 day period. The micro-hardness was recorded each day and the lesion depth was measured after 5 days. The micro-hardness of the experimental sides of groups 2, 3 and 4 were significantly higher than that of their control sides and the experimental side of group 1 during the experimental period (p<0.05) except on the 5th day. The enamel surfaces of treatment groups 2, 3 and 4 showed significantly higher resistance to mineral loss in terms of the erosion depth (p<0.05) than group 1 and their control sides. There was no statistically significant difference among group 2, 3 and 4, indicating that the fluoride varnish and tapes produce similar results. Fluoride adhesive tapes are effective in reducing the progression of erosion and can be recommended for young patients who are more susceptible to dental erosion.

Effects of nursing intervention programs for women with gestational diabetes: a systematic review of randomized controlled trials (임신성 당뇨병을 가진 임산부를 위한 간호중재 프로그램의 효과: 무작위 대조군 실험연구의 체계적 문헌고찰)

  • Kim, JooHee;Chung, ChaeWeon
    • Women's Health Nursing
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    • v.27 no.1
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    • pp.14-26
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    • 2021
  • Purpose: This study aimed to identify the effects of nursing intervention programs for women with gestational diabetes mellitus (GDM) through a critical review of recent studies. Methods: Studies related to effects of nursing intervention programs for women with GDM published in English or Korean between 2000 and 2019 were extracted from 10 electronic databases. The quality of the studies was evaluated and double-checked for accuracy by two reviewers using the Revised Cochrane Risk-of-Bias tool for randomized controlled trials. Results: Twenty studies were selected, of which 19 had a low risk of bias and one had a high risk of bias. Interventions fell into six main groups: (1) integrated interventions, (2) self-monitoring of blood glucose levels, (3) dietary interventions, (4) exercise, (5) psychotherapy, and (6) complementary therapy. This review found that nursing interventions for GDM were of many types, and integrated interventions were the most common. However, low-carbohydrate diets and blood glucose monitoring interventions did not show statistically significant results. Evidence shows that various nursing intervention programs applied to GDM improved diverse aspects of maternal, fetal, and neonatal health, including both physical and psychological aspects. Conclusion: The composition and delivery of integrated interventions continue to evolve, and these interventions affect physical and psychological indicators. Although interventions affecting physical health indicators (e.g., blood glucose levels, diet, and exercise) are important, many studies have shown that programs including psycho-emotional nursing interventions related to anxiety, depression, stress, self- efficacy, and self-management are also highly useful.

The Effects of Regular Pilates Exercise on Blood pressure and Pulmonary Variables (규칙적인 필라테스 운동이 심혈관 및 호흡 변인에 미치는 영향)

  • Lee, Gyu-Chang;Lee, Dong-Yeop;Yu, Jae-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.7
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    • pp.3088-3095
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    • 2011
  • The purpose of this study was to investigate the effects of Pilates exercises on the improvement of blood pressure and respiratory function. 36 subjects which were randomly divided into Pilates exercises group(n=18) and control group(n=18). Subjects in the Pilates exercises group were regularly participated in Pilates exercise program for 8 weeks. We were measured the blood pressure and respiratory function such as blood pressure, VO2max, METs, and Anaerobic threshold at before and after the experiment. After 8 weeks, in Pilate exercises group, there were significant improvement on blood pressure and respiratory function except the diastolic blood pressure. And subjects participated in Pilates exercise group were significantly improved compared to control group on systolic blood pressure, VO2max, METs, and Anaerobic threshold. But in control group, there were no significant differences. In conclusion, regular participation in Pilates exercises improved the blood pressure and respiratory function. These results suggest that Pilates exercise is the method that replace aerobic exercise.

Effects of Mechanical Horseback Riding Training on Trunk Control and Balance function in Stroke patients (뇌졸중 환자의 체간조절, 균형능력에 기계적 승마치료가 미치는 영향)

  • Song, Myung-Soo;Kang, Tae-Woo;Kim, Su-Mi;Noh, Hyeon-Jeong
    • Journal of Digital Convergence
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    • v.11 no.12
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    • pp.487-494
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    • 2013
  • The purpose of this study was to determine the effect of mechanical horseback riding training on trunk control, balance function in stroke patients. 15 stroke patients were recruited for this study. The subjects were randomly assigned to two groups: experimental(n=7) and control(n=8). All subjects received a routine physical therapy. The mechanical horseback riding training was for 30 min in the case of the EG subjects. This study was carried out approximately 8 weeks from March 4 to May 3. The assessment tools of this study involved the trunk control test, postural assessment scale for stroke, Berg balance scale and timed up and go test. The measurements were recorded before the intervention and after the intervention. In the cases of the EG subjects and CG subjects, the variables measured after the intervention significantly differed from trunk control test, postural assessment scale for stroke, Berg balance scale and timed up and go test before the intervention (p<.05). Also, there were significant differences in trunk control test, postural assessment scale for stroke, Berg balance scale and timed up and go test at post test between the 2 groups (p<.05). The findings indicate that mechanical horseback riding training exerts a positive effect on trunk control, balance function in stroke patients. Further studies are required to generalize the result of this study.

The Effect of Lumbosacral Stabilization Exercise on Oswestry Disability Index and Gait Velocity of Patients with Chronic Low Back Pain (허리엉치 안정화운동이 만성허리통증환자의 허리통증장애지수와 보행속도에 미치는 영향)

  • Kang, Jeong-Il;Jeong, Dae-Keun
    • Journal of Digital Convergence
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    • v.11 no.8
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    • pp.243-250
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    • 2013
  • The present study is to determine the effect of lumbosacral stabilization exercise program on back pain disorder and gait velocity of patients with chronic low back pain. The subject was extracted randomly from 34 patients with chronic low back pain and divided into 18 patients of experimental group and 16 patients of control group. Before the experiment, the Oswestry disability index examination and analysis of gait speed were performed. Then, a conventional interventional therapy of physiotherapy was performed with the experimental group along with the lumbosacral stabilization exercise while only the conventional interventional therapy was done to the control group. Both groups did the above treatment every 30 minutes, four times a week for four weeks. Then, post-examination was carried out followed by comparing the back pain disorder index and gait velocity before and after the experiment for the two groups. The back pain disorder index showed that both experimental and control groups had significant difference within the group (p>.01)(p>.05), With regard to the gait velocity, both experimental and control groups had a significant difference within the experimental group and between the groups (p>.001)(p>.05).

Effect of Death Education Program on Self-Esteem, Spiritual Well-Being, and Pain of Adults (죽음교육 프로그램이 성인의 자아존중감, 영적안녕, 통증에 미치는 효과)

  • Kim, Bock-Ryun;Oh, Chung-uk;Kang, Hye-kyung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.9
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    • pp.156-162
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    • 2016
  • This study was conducted to investigate the effects of a death education program on self-esteem, spiritual well-being, and pain in adults. This investigations employed a nonequivalent control group non-synchronized design, and was performed in C hospital located in Chungju, Chungcheongbukdo province, Korea from January 4-13, 2016. The study included 48 participants who agreed to enrolled. Participants were randomly divided into an experimental and a control group of 22 and 26 applicants each. Participants (n=22) in the experimental group participated in the death education program for 2 hours, three times a week for 2 weeks. The effects of treatment were measured using a structured questionnaire to evaluate self-esteem, spiritual well-being, and pain before and after 2 weeks of intervention. Data were analyzed using a t-test, chi-squared test, Fisher's Exact-test and a paired t-test. The experimental group showed significantly increased self-esteem (P<0.002) and spiritual well-being (P<0.015), and significantly reduced pain (P<0.014) compared to the control group after 2 weeks of intervention. Overall, the death education program was shown to be an effective nursing intervention for adults; therefore, of its use in various fields should be considered.

Effects of Cognitive Training Using Tablet PC Applications on Cognitive Function, Daily Living and Satisfaction in Subacute Stroke Patients (테블릿 pc 어플리케이션을 사용한 인지훈련이 아급성 뇌졸중 환자의 인지기능, 일상생활 및 만족감에 미치는 영향)

  • Moon, Jong-Hoon;Won, Young-Sik
    • The Journal of the Korea institute of electronic communication sciences
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    • v.12 no.1
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    • pp.219-228
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    • 2017
  • The aim of this study was investigated the effect of cognitive training using tablet pc applications on cognitive function, daily living, and satisfaction in subacute stroke patients. This study participated in fourteen subacute stroke inpatients, in I general hospital, at located in Incheon. All subjects assigned that randomized each seven patients in experimental and control group. Two groups received to traditional cognitive therapy during half hour/day, 5 times per week, for 4 weeks. Experimental group performed additionally that cognitive training using tablet pc applications for 30 min/day. The outcome measures were the K-MMSE(: Korea-Mini Mental State Examination), MoCA-K(: Montreal Cognitive Assessments-Korea), MBI(: Modified Barthel Index), VAS(: Visual Analog Scale) for cognitive function, daily living, satisfaction. In results, Both group showed significant improvements after intervention in MoCA-K, MBI(p<.05). In comparison of change between two groups, experimental group showed significant improvements than control group in MoCA-K(p<.05). In comparison of satisfaction of two groups, both group was not significant difference(p>.05). we suggested that Cognitive training using tablet pc applications expected to positive effects the improvements of cognitive function in subacute stroke patients.

The Effects of Orofacial Training Video Program using Smart Device on Oral Cavity Structure and Function, Diadochokinetic Rate in Acute Stroke Patients with Dysarthria (스마트 기기를 활용한 구강안면 훈련 영상 프로그램이 마비말장애가 있는 급성 뇌졸중 환자의 구강 구조 및 기능과 조음교대운동속도에 미치는 효과)

  • Moon, Jong-Hoon;Won, Young-Sik
    • The Journal of the Korea institute of electronic communication sciences
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    • v.12 no.2
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    • pp.391-400
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    • 2017
  • The purpose of this study was investigated the effect of orofacial training video program using smart device on oral cavity structure and function, diadochokinetic rate in acute stroke patients with dysarthria. Present study participated in fourteen acute stroke patients with dysarthria. All subjects assigned that randomized each seven patients in experimental and control group. Subjects of two groups received conventional rehabilitation therapy for 4 weeks. Experimental group performed additionally that orofacial training video program using smart device, supervised under caregivers, during 30 min/day. The outcome measures were the oral cavity structure and function of subscale for KOMSE(: Korean Oro-motor Mechanism Screening Examination), AMR(: Alternating Motion Rate), SMR(: Sequential Motion Rate). In results, Both group showed significant improvements after intervention in all assessments(p<.05). In comparison of change between two groups, experimental group showed significant improvements than control group in oral cavity function, /p ə/ and /tə/ of AMR(p<.05). We suggested that orofacial training video program using smart device expected to positive effects the improvements of oral cavity and articulator function in acute stroke patients with dysarthria.