• Title/Summary/Keyword: 무게비

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Influence of Protaetia brevitarsis Extract on Liver Damage Induced by Carbon Tetrachloride and Ethanol in Rats (에탄올 및 사염화탄소의 긴 손상에 미치는 흰점박이꽃무지 추출물의 영향)

  • 이형철;황상구;강영국;손영옥;문자영
    • Journal of Life Science
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    • v.11 no.5
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    • pp.405-414
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    • 2001
  • Protaetia brevitarsis has been utilized as an ingredient of the description for the treatment of patients with chronic hepatic diseases in oriental medicine. This study was attempted to investigate whether Protaetia brevitarsis extract(PBE) protects or modulates the liver injuries induced by carbon tetrachloride or ethanol in Sprageue-Dawley rate. The liver injuries of rats induced by the treatment of carbon tetrachloride or ethanol were manifested by the observation of the significant changes in liver weight, serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities, serum thiobarbituric acid reactive substances (TBARS), and microsomal detocification enzymes(cytochrome P_450), cytochrome b$_{5}$, and cytochrome b$_{5}$ reductase).The effect of PBF on the liver damage induced by the chemicals was evaluated with the extent modulated in change of biochemical parameters above. Exposure to ethanol alone resulted a significant change in the ration of liver per body weight, ALT activity, and microsomal detoxification enzymes (cytochrome P_450, cytochrome b$_{5}$, and cytochrome b$_{5}$ reductase), but did not significantly changes in the levels of serum AST activity and TBARS. Pretreatment coith PBE did not modulate the alteration of the ratio of liver to body weigth, and the activities of serum aminotransferascs (AST. ALT), TBARS, and micro somal detoxification enzyme (cytochrome p_450, cytochrome b$_{5}$,and cytochrome b$_{5}$ reductase. These result suggested that PBE has not appreciable therapeutic effect on carbon tetrachloride or ethanol induced hepatotoxicity.

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Antiobese Effects of Diet Containing Medicinal Plant Water Extracts in High Fat Diet-Induced Obese Mice (약용식물 물 추출물들 혼합식이에 의한 고지방식이로 유도된 마우스의 비만 억제효과)

  • Seo, Dong-Joo;Chung, Mi-Ja;Kim, Dae-Jung;Choe, Myeon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.11
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    • pp.1522-1527
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    • 2009
  • We investigated the effects of feeding diet containing medicinal plant water extracts (MPWEs) on body weight, epididymal adipose tissue weight, adipocyte size of epididymal adipose tissue and plasma lipid levels in high fat (HF) diet-induced obese mice. To test antiobese effects of diet containing the MPWEs, C57BL/6J mice were fed with HF diet for 11 weeks. In the last 6 weeks, the HF diet was supplemented with 0 (HFD) or MPWEs (5 g/kg, HFD+MPWEs) or orlistat [0.5 g/kg, HFD+orlistat (antiobesity drug)]. The HF-free diet group was fed normal chow for 11 weeks. Eleven-weeks feeding with HFD resulted in significant increase in lipid levels, body weight, liver and epididymal adipose tissue weights, compared with the HF-free group. Diet containing MPWEs significantly reduced plasma total cholesterol, LDL-cholesterol, triglyceride and glucose concentrations as well as body weight, liver weight and epididymal adipose tissue weight. Plasma triglyceride levels were significantly lower in the HFD+Forlistat group after 6 weeks and a similar effect was found with HFD+MPWEs group. The adipocyte size of epididymal adipose tissue in HFD group was significantly larger than those of HF-free group. MPWEs and orlistat (positive control) significantly decreased the size of epididymal adipocytes but orlistat was slightly more effective than MPWEs. These results suggest that oral feeding of the MPWEs may have antiobesity effects by suppressing body weight gain, adipose tissue formation and adipocyte size increase.

The Effect of Environmental Factors on the Hydrolysis Characteristics of Lipase (환경인자가 리파제의 가수분해 특성에 미치는 영향)

  • Park, Geon-Gyu;Kim, Eun-Gi;Heo, Byeong-Gi
    • KSBB Journal
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    • v.14 no.4
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    • pp.511-516
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    • 1999
  • The effects of environmental and compositon factors, such as reaction time, metal ions, pH, agitation speed, the weight ratio of water to oil, and the weight of enzyme, on the hydrolysis of oils by Lipase-OF were investigated. In case of oils with low melting point, the optimum temperature of hydrolysis were the enzyme activity was maximum was 37$^{\circ}C$. However, when the melting temperature was higher than 4$0^{\circ}C$, the optimum temperature was around the fusion temperature. The activity of Lipase-OF decreased very rapidly with increase of temperature in the range of higher than 45$^{\circ}C$ and the activity perished above $65^{\circ}C$. The effect of agitation speed was investigated from 150 to 650 rpm. The hydrolysis of oils increased as the agitation speed increased up to 350 rpm, but it did not increase any more above 350 rpm. The weight ratio of water to oil was changed from 1 : 9 to 9 : 1 for the investigation of the effect on the hydrolusis. The weight ratio for maximum hydrolysis was 1 : 1. $Ca^{2+}\;and\;Mg^{2+}$ among various metal ions had some effect on the stimulation of hydrolysis. The optimum concentration of the ions was about 100ppm at which the hydrolysis increased, compared with that of distilled water, by 2 to 3%. The Optimum pH of Lipase-OF was 7. The hydrolysis decreased as the pH decreased as the pH decreased and also decreased as the pH increased. The content of enzyme affected the hydrolysis of oil. The hydrolysis increased with the content of Lipase-OF in the range of less than 0.013 wt% of substrate. However, the increase of hydrolysis with the content of Lipase-OF ceased above 0.013 wt%. The experiments investigating the effect of environmental and composition factors on the hydrolysis of oils showed that the optimum temperature was 37$^{\circ}C$, the pH 7, the concentration of $Ca^{2+}\;or\;Mg^{2+}$ 100 ppm, the agitation speed 350 rpm, the weight ratio of water to oil 1 : 1, and the content of Lipase-OF 0.013 wt% of substrate.

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Anti-Obesity Effect of Enterococcus faecalis MD366 isolated from Raw Milk in Diet-Induced Obese Mice (원유에서 분리한 Enterococcus faecalis MD366가 고지방식이를 급여한 마우스의 비만 억제에 미치는 영향)

  • Park, Sun-Young;Cho, Seong-A;Han, Noo-Ri;Seong, Ki-Seung;Lim, Sang-Dong
    • Journal of Dairy Science and Biotechnology
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    • v.32 no.2
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    • pp.163-167
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    • 2014
  • This study aimed to investigate the anti-obesity effects of Enterococcus faecalis MD366, isolated from raw milk, in diet-induced obese mice. To examine the effect, male C57BL/6J mice were fed for six weeks on three different diets, i.e., a normal diet and orally administrated saline solution (ND), a high-fat diet and orally administrated saline solution (HFD), and a high-fat diet and orally administrated E. faecalis MD366 ($10^9CFU/day$) in saline solution (HFD+MD366). After six weeks, the rate of increase in body weight was 18.1% lower in the HFD+MD366 group compared to that in the HFD group. In addition, the weight of epididymal fat pad in the HFD+MD366 group was lower than that in the HFD group. The average levels of triglycerides, total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) were slightly reduced in the HFD+MD366 group compared to those in the HFD group. However, there were no significant differences between the groups. Measuring the adipocytes revealed that the percentage of adipocytes with a size of $2,000{\mu}m^2$ was higher than the percentages of other size classes in ND and HFD+MD366 groups, while the percentage of adipocytes larger than $5,000{\mu}m^2$ was highest in the HFD group. The mean adipocyte size in the HFD+MD366 group was smaller than that in the HFD group.

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미생물비료 인산가용화균이 오이의 생산량에 미치는 영향

  • Lee, Tae-Geun;Park, Dong-Ha;Ju, Yeong-Jik
    • Proceedings of the Korean Society of Organic Agriculture Conference
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    • 2002.12a
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    • pp.74-82
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    • 2002
  • 난용성 인산염을 가용화 시키는 Penicillium sp. PS-113와 Lactobacillus sp. 를 이용하여온실에서 오이에 대한 생육 실험을 실시하였다. 실험 결과는 다음과 같다. Penicillium sp. PS-113 $5.0{\times}106cfu/ml$ + Lactobacillus sp. $6{\times}106cfu/ml $동시 처리구에서 평균 오이 길이는 대조구에 비하여 3cm 더 긴것으로 조사되었고, 오이 낱개의 무게는 310.6g으로 무처리구에 비하여 89.2g 이 증가하였으며, 오이 전체 생산량은 10681.7g로 무처리구와 비교해 볼 때 4517.3g이 많아 생산량이 73% 증가하였다. Penicillium sp. PS-113 $5.0{\times}105cfu/ml$ 단독처리와 Penicillium sp. PS-113 $5.0{\times}105cfu/ml$ + Lactobacillus sp. $6{\times}106cfu/ml$의 동시 처리구도 오이의 평균 무게와 길이에 있어 무처리구보다 약간씩 더 높았다. Penicillium sp. PS-113 $5.0{\times}105cfu/ml$ + Lactobacillus sp. $6{\times}106cfu/ml$의 동시처리구는 무처리에 비하여 오이의 수가 2개 적었으나 오이 전체 생산량은 무처리구에 비하여 Penicillium sp. PS-113 $5.0{\times}105cfu/ml$ 단독 처리구에서 53.7%, Penicillium sp. PS-113 $5.0{\times}104cfu/ml$ + Lactobacillus sp. $6{\times}106cfu/ml$ 동시 처리구에서 48.5% 증가되었다. 따라서 인산가용화균의 처리가 오이의 생산성을 증대시키는 것으로 나타났다.

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Analysis of Sound Insulation Performance of Honeycomb Composite Panels for Cruise Ships (크루즈선박용 허니컴 패널의 차음 성능 해석)

  • Kwon, Hyun-Wung;Hong, Suk-Yoon;Roh, Jae-Ouk;Song, Jee-Hun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.20 no.2
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    • pp.234-240
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    • 2014
  • In this paper, the interface matrix of honeycomb composite panel has been derived by the governing equation of a honeycomb sandwich panel. The interface matrix of honeycomb panel is added to the previously developed transfer matrix method, thus analysis of the multi-layered insulation composite panel with honeycomb is accomplished. Furthermore, predictions of sound transmission loss(STL) for the ship's insulation panel with honeycomb and mineral wool are presented. The insulation performance of the honeycomb used for skin of the ship's insulation panel is better than that of 0.35 mm steel panel by 2dB, approximately. Although honeycomb panel has inefficient insulation performance beside steel panel, honeycomb panel achieve improvements in the performance of weight reduction. The surface density of the panel with honeycomb is rather than with steel by $5.2kg/m^2$. It is decrease in weight by 31.7 %.

Selection of Coating Materials for Italian Ryegrass Seed and Its Germination Assessment (이탈리안 라이그라스 종자 코팅을 위한 피복 재료 선발 및 발아 평가)

  • Jang, Hyeonsoo;Bae, Hui-su;Lee, Yun-ho;Kim, Dae-Uk;Ahn, Seung-hyun;Youn, Jong-Tak;Kim, Uk-Han
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.66 no.4
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    • pp.435-442
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    • 2021
  • This study was conducted to determine an appropriate coating method for mechanized sowing of small and light Italian ryegrass seeds. In the case of manufacturing coated seeds, 2% PVA was superior as an adhesive compared to PVP and Tween80. Calcium carbonate + talc adhered to the seeds smoothly and well and the seed weight was higher than that of the other coating materials. The germination percentage of seeds coated with calcium carbonate + talc was 95.8%, which was not significantly different from 96.5% of the control group, but the mean daily germination was the highest. As the coverage ratio of calcium carbonate + talc increased, the strength tended to increase when coated at 1.5 times the seed weight. There was no difference in the germination rate and plant height compared to the control group according to the coverage ratio.

Kinematic Characteristics of the Thrower's COM and the Shot in Shot Put : The Woman Record Holder of Korea (포환던지기 동작 시 포환과 신체 무게중심의 운동학적 특성 : 한국 여자 기록보유자를 대상으로)

  • Lee, Dong-Jin;Cho, Byung-Jun;Lee, Myung-Sun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.11
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    • pp.5148-5154
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    • 2012
  • The purpose of this study was to analyze the kinematic characteristics of the thrower's center of mass (COM) and the shot that her performance hits record high for the 29th National Athletic Competition. Two S-VHS video cameras were used to visualize. The Direct Linear Transformation technique was employed to paint a clear picture in the three dimensional coordination. Kwon3D was used to analyze the data. The results showed that release velocity and height were 13.73 m/s and 198.6 cm(119% by height ratio), respectively, which is considered as peak performance comparing an extensive review of previous literature on the shot put. Release angle was $34^{\circ}$, which is lower than the previous studies. The path of thrower's center of mass is needed to travel in a release direction during the flight phase. The vertical movement of the thrower's center of mass during the driving should be controlled. At release, the perfact timing is required without vertical and horizontal movements of the thrower's center of mass.

A Comparison Analysis of EMG according to Weight Class and Increase Record of Clean and Jerk Techniques Weightlifting in High School Female Weight Lifters (고교여자역도 선수들의 용상동작 수행 시 체급별 무게증가에 따른 EMG변화 비교 분석)

  • Park, Il-Bong;Yeo, Nam-Hwoeh;Kim, Jung-Tae
    • Korean Journal of Applied Biomechanics
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    • v.18 no.2
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    • pp.105-114
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    • 2008
  • The purpose of this study was to compare of muscles in clean and jerk techniques between 69kg class(n=3), 58kg class(n=3) in high school female weight lifters using EMG(electromyographic) system. EMG analysis were executed on 6 major muscles and dividing clean and jerk techniques into 6 phases. In that result, in the difference by weight, it was shown that EMG value increased gradually as the weight is raised of all muscles group & phases in 58kg class. In EMG signal scale by classes, it was shown that EMG signal scale didn't increase according to class & weight. In the result of this study, that EMG value was inconsistent in 69kg class is showing that the consideration of the technical factor together with muscle power has positive affect more on the performance improvement in the heavy class.

A Study on Aircraft Sensitivity Analysis for C.G Variation of Longitudinal Axis (항공기 세로축 무게중심의 변화에 따른 민감도 해석에 관한 연구)

  • 김종섭
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.34 no.6
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    • pp.83-91
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    • 2006
  • An advanced method of Relaxed Static Stability (RSS) is utilized for improving the aerodynamic performance of modern version supersonic jet fighter aircraft. The flight control system utilizes RSS criteria in longitudinal axis to achieve performance enhancements and improve stability. The flight control law of T-50 advanced trainer employs RSS concept in order to improve the aerodynamic performance and guarantee aircraft stability. The longitudinal center of gravity(X-c.g) varies as a function of external stores, fuel state and gear position. Shifts in X-c.g relate directly to longitudinal static margin in aircraft stability. This paper deals the maximum aft X-c.g for critical aircraft loadings and checks static margin limits using sensitivity such as damping, natural frequency, gain and phase margin. And nonlinear analysis was conducted for such as short period input. And also, this paper shows the T-50 aircraft stability based on the result of high angle of attack flight such as upright and inverted departure.