• Journal of Conservation Science
• /
• v.33 no.1
• /
• pp.25-33
• /
• 2017

The stone lantern of the four guardian kings in the Beopjusa temple at Boeun was mainly made of biotite granodiorite consisting of porphyritic-textured potassium feldspar and included in ilmenite series. A base stone made of alkali granite was buried, after founded its place during an earlier restoration process. Cracking and break out are noticeable on this object. In addition, discoloration, salt crusting, and epiphytes were observed. The lantern was vulnerable in terms of physical and structural stability caused by cracking in the front and back of the light chamber and in the non-horizontal direction. According to the conservational condition of the stone lantern, structural reinforcement was carried out based on calculations, including those on the position, size, and anchor length of the titanium stiffener. Chemical and biological pollutants were washed off without damage to the surface of the stone material. Oxygenated iron pieces were replaced with titanium. Ethyl silicate was applied to the surface of the lantern for consolidation and smooth drainage.

• Korean Journal of Food Science and Technology
• /
• v.22 no.5
• /
• pp.503-508
• /
• 1990

Stews were prepared by 2 processes and 4 treatments, and stored for 3 different storage periods. The two processes were beef cooked in a stew and stored in a polyethylene container at $5^{\circ}C(P1)$ and in a barrier bag at $0^{\circ}C(P2)$. The four treatments were beef cooked alone (T1), with onions (T2), with carrots (T3) and with onions and carrots (T4). Stews in P1 were stored for 0, 2 and 4 days and stews in P2 were stored for 0, 2 and 4weeks. Cooking decreased the cephalin content by 39%. the lecithin content by 21% and most of the prolipid fatty acid concentrations as well as the fatty aldehyde levels in the phospholipids of beef from stew. Process or storage did not significantly affect the level of either phospholipids. however cooking beef with carrots seemed to exhibit some protection against hydrolysis of cephalin. P1 stews had a higher TBA-value (p<0.05) than P2 stews, and the TBA-value of P1 stews increased linearly during 4 days storage. The TBA-value was not affected (p<0.05) by treatment for any of the stews and did not change significantly during 4 weeks storage in P2 stews.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.32 no.2
• /
• pp.263-268
• /
• 2003

This study was designed to test the effect of Korean traditional teas on lipid levels in lead (Pb)-administered rats. Male rats were divided into normal, Pb-control (rb-Con) and Pb-water extract of traditional teas (green tea: GWE, persimmon leaf: PWE, safflower seed: SWE, Solomon's seal: SSWE) groups. Pb intoxication was induced by administration lead acetate (25 mg/kg. BW, oral) weekly. The extract was administered based on 1.26 g of raw traditional tea/g BWday for 4 weeks. Net weight gain and feed intake were significantly lower in the Pb-Con group than in the normal group, whereas they were tended to increase by traditional teas supplements. Both Plasma and hepatic total cholesterol and triglyceride concentration were lower in the traditional teas supplemented groups compared to the Pb-Con group. Plasma VLDL-cholesterol and LDL-cholesterol levels were significantly increased by Pb ad-ministration, whereas HDL-cholesterol concentration was significantly lower in the Pb-Con group than in the normal group. However, water extracts of green tea, persimmon leaf, safflower seed and solomon's seal supplementation improved changes of the plasma lipoprotein-cholesterol levels in Pb administered rats.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.32 no.2
• /
• pp.191-196
• /
• 2003

This study was performed to investigate the effect of water extract of green tea (GT), persimmon leaf (PL) and safflower seed (SS) on heme synthesis and erythrocyte antioxidant enzyme activities in lead (Pb)-administered rats. Male rats were divided into five groups. a normal, Pb-control (Pb-Con), Pb-GT, Pb-PL and Pb-55 groups with ten rats per group. Pb (25 mg/kg. BW) was orally administerd once a day for 4 weeks. The extract of GT, PL and 55 were administered based on 1.26 g of raw traditional tea/kg BW/day. Blood hematocrit, homoglobin level and red blood cell counts were significantly lower in rb-Con group than in normal group. However, the supplementation of GT, PL and 55 were effective to improve the hematological parameters. Plasma AST and ALT activities were significantly lower in Pb-GT, Pb-PL, Pb-SS groups than in Pb-Con group. The $\delta$ -amino-levulinic acid dehydratase (ALAD) activity of blood and liver were significantly lowered in Pb-Con group com-pared to those of the normal group. The ALAD activity in Pb administered rats was recovered to tile normal level by the water extract of GT, PL and 55 supplementation. Erythrocyte superoxide dismutase and catalse activities were significantly higher in Pb-Con group than in normal group, whereas glutathione peroxidase activity was lowered in Pb administered rats. The extract of GT, PL and SS supplement attenuated changes of these erythrocyte antioxidant enzyme activities by Pb intoxication.

• Journal of Digital Convergence
• /
• v.18 no.3
• /
• pp.267-273
• /
• 2020

To determine the biological effects of exercise on hippocampus in mice brain exposed to radiofrequency radiaton (RF), the expression of AMPKα, p-AMPKα, ERK1/2, p-ERK1/2, p38, and p-p38 protein in the mouse exposed to RF were investigated in the hippocampal tissues, Western blot method was used to compare the protein expression levels for each molecule. Significant increases in protein expression of individual and phosphorylated molecules were observed in the spontaneous exercise group, and the expression of these molecules was notably decreased in the RF exposure and spontaneous exercise group. This study shows that neuroplasticity can be increased by exercise in hippocampus that is responsible for memory, but memory and cognitive function may be affected by exposure to RF. We may expect clinically interesting results on dementia or Alzheimer disease if we proceed further investigation on the effect of RF.

• Journal of the East Asian Society of Dietary Life
• /
• v.22 no.6
• /
• pp.812-817
• /
• 2012

This study was performed to investigate the antioxidant activities and the melanin inhibitory effects of Hippophae rhamnoides L. fruit extracts. Two in vitro methods were used; the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method to determine antioxidant activity and measurements of the inhibitory effects of tyrosinase activity to determine melanogenesis in B16/F10 melanoma cells. The radical scavenging activity of the extract was 56.0% at $700{\mu}g/mL$, similar to ascorbic acid (56.9%), in the DPPH assay. The tyrosinase inhibitory activity of the extract was 52.1% and 73.4% at 100 and $500{\mu}g/mL$, which is also similar to ascorbic acid. In B16/F10 mouse melanoma cells, the extract inhibited melanin synthesis by 56% at $500{\mu}g/mL$, a more prominent inhibition of melanin synthesis compared to extracts from arbutin. These results suggest that extracts from H. rhamnoides L. have antioxidant activity and skin-whitening effects; allowing their application in cosmetics as a natural product.

• IMMUNE NETWORK
• /
• v.2 no.1
• /
• pp.60-64
• /
• 2002

Background: Chemotherapy with 5-fluorouracil (5-FU) has been one of the mainstay in breast cancer treatment. The effects of high dose 5-FU on cell cycle regulation were studied in breast caner cells. Methods: A breast cancer cell line MCF-7 was used. Protein expressions of G1/S cyclins, $p21^{Waf1/Cip1}$, cdk2, E2F1 and retinoblastoma were tested by western blot analysis. Immunoprecipitation and immune complex kinase assay were done for the assessment of E2F1/RB interacton and the activity of cdk2 respectively. Results: $p21^{Waf1/Cip1}$ expression was barely detectable in control cells. With addition of 5-FU level of $p21^{Waf1/Cip1}$ were induced and cyclin D3 level was decreased as cell growth decreases. In accordance with increased expression of $p21^{Waf1/Cip1}$, cyclin E-associated cdk2 kinase activity was reduced. Retinoblastoma protein (RB) became dephosphorylated and E2F-1 binding activity with RB was increased. Conclusion: In this situation of high concentration of 5-FU breast cancer cells tend to be G1/S cell cycle arrested. Overexpression of $p21^{Waf1/Cip1}$ and dephosphorylation of RB may mediate the effectss of 5-FU by inhibiting E2F-1 activity, which contributes to G1/S cell cycle arrest. These results could be an indicating landmark for further study of high dose chemotherapy with 5-FU.

• International Commerce and Information Review
• /
• v.17 no.1
• /
• pp.217-240
• /
• 2015

This paper uses the modified gravity model of international trade to examine the impact of ODA on the export of Korea to 28 aid recipients. In this perspective, the study includes recipient's economic size, trade openness, population, donor's scale of aid and distance between them as key determinants of the export of Korea by using panel data over the period of 2005-2012. To do this task, important econometric methods are fulfilled to test the model adequately, such as panel unit root and panel co-integration test. In addition, the study incorporated the panel OLS, panel GLM and panel EGLS methods. The empirical analysis clearly showed that an increase in Korea's ODA promotes its own exports. The coefficients of recipients's per capita GDP, population and trade openness have a positive impact on Korea's export respectively, while distance between them has a negative impact. Regarding regional dummy variables, aid for the region of Africa and America have a negative impact on Korea's export. Overall, the main implication of this study is that even if it emphasized Korea's economic interests as determinants of ODA disbursements, but it also suggests that an improvement of recipient's economic development, income distribution and educational environment can be an important concern in the future.

• The Journal of Korean Academy of Prosthodontics
• /
• v.50 no.4
• /
• pp.324-329
• /
• 2012

Excessive tooth wear causes loss of tooth structure, disharmony of occlusal plane, functional and esthetic problems. Although the decrease of occlusal vertical dimension may be compensated by growth of alveolar bone, if the length of tooth is not enough for the retention of restoration, minimum increase of occlusal vertical dimension is required without discomfort of the patient. In this case, 33-year-old woman drinks more than 1 liter of soft drinks a day and has bruxism in night time, visited in Seoul National University Dental Hospital with chief complaint of generalized tooth wear and related esthetic and functional problems. It was considered as a loss of occlusal vertical dimension based on the accelerated tooth wear caused by erosion and bruxism and facial appearance, phonetic, esthetic, functional evaluations. It was planned to raise occlusal vertical dimension by provisional restoration two times for patient's adaptation, 3 mm and 2 mm each, total 5 mm. Confirming no discomfort and clinical symptom during total 16 weeks after restoration with provisional fixed restoration, it was restored with porcelain fused to gold crown and bridge. Because the patient was young woman, anterior teeth were restored with collarless porcelain fused to gold crown. This case presents that satisfactory esthetic and functional result by full mouth rehabilitation with increase of occlusal vertical dimension.

• Proceedings of the Korean Society of Computer Information Conference
• /
• 2014.07a
• /
• pp.303-306
• /
• 2014

수많은 사람들이 게임을 제작 및 개발함에 있어, 많은 학자들이 다양한 방법으로 오랜 세월에 걸쳐 연구한 게임의 인문학적 정의 및 재미 이론은 현대의 게임 개발에 있어서도 그 이론적 배경을 담당하는 주춧돌의 역할을 맡고 있다. 본 논문에서는 청강문화산업대학교 게임전공의 게임 개발 프로젝트의 일환으로 구성된 '안드로메다' 팀이 Unity 3D 엔진을 기반으로 제작한 3D 생존 어드벤처 게임 "1 Hour"를 개발한 과정을 기술하였고, 그 과정에서 재미 이론의 '패턴'에 근거하여 플레이어로 하여금 몰입을 유발시키는 어드벤처 장르의 게임 디자인을 제시하는 것을 이번 연구의 목적으로 하였다. 연구 과정은 문헌 연구 및 개발 게임("1 Hour")의 플레이 테스트 등을 통해 게임에서의 몰입의 과정을 분석하였고, 몰입 유발 효과 증명을 위해 '패턴과 몰입의 상관관계'에 대한 가설들을 수립하고 실험을 실시하여 그 결과를 분석하였다.