• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.9
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• pp.211-226
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• 2019

Pig CD45, the leukocyte common antigen, is encoded by the PTPRC gene and CD45 is a T cell-type specific tyrosine phosphatase with alternative splicing of its exons. The CD45 is a coordinated regulator of T cell antigen receptor (TCR) signal transduction achieved by dephosphorylating the phosphotyrosine of its substances, including $CD3{\zeta}$ chain of TCR, Lck, Fyn, and Zap-70 kinase. A dysregulation of CD45 is associated with a multitude of immune disease and has been a target for immuno-drug discovery. To characterize its key structural features with the effects of regulating TCR signaling, this study predicted the unknown structure of pig CD45RO (the smallest isoform) and the complex structure bound to the ITAM (REEpYDV) of $CD3{\zeta}$ chain via homology modeling and docking the peptide, based on the known human CD45 structures. These features were integrated into the structural plasticity of extracellular domains and functional KNRY and PTP signature motifs (the role of a narrow entrance into ITAM binding site) of the tyrosine phosphatase domains in a cytoplasmic region from pig CD45RO. This contributes to the selective recognition of phosphotyrosine from its substrates by adjusting the structural stability and binding affinity of the complex. The characterized features of pigCD45RO can be applied in virtual screening of the T-cell specific immunomodulator.

• Journal of Digital Convergence
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• v.19 no.6
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• pp.175-184
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• 2021

The purpose of this study is to investigate the effect of the strategic role of the human resources department in the manufacturing industry on organizational effectiveness through education and training satisfaction. Among the data from the 7th human capital company panel survey, data from the manufacturing industry were used and analyzed through a structural equation model. The results of this study are as follows: First, the strategic role of the HR department has a positive effect on satisfaction with education and training. Second, satisfaction with education and training and the strategic role of HR departments have a positive effect on job satisfaction among organizational effectiveness. Third, it was confirmed that education and training satisfaction has a mediating effect on the relationship between the HR department's strategic role and job satisfaction. The results of this study are expected to become the basis for expanding the authority and responsibilities of the HR department, which is an important factor in overcoming the crisis faced by SMEs as well as innovation, and redefining their role.

• Journal of the Korean Geotechnical Society
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• v.37 no.11
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• pp.107-118
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• 2021

Scan-to-BIM can be precisely mod eled by measuring structures with Light Detection And Ranging (LiDAR) and build ing a 3D BIM (Building Information Modeling) model based on it, but has a limitation in that it consumes a lot of manpower, time, and cost. To overcome these limitations, studies are being conducted to perform semantic segmentation of 3D point cloud data applying deep learning algorithms, but studies on how segmentation result changes depending on learning data are insufficient. In this study, a parametric study was conducted to determine how the size and track type of railroad tunnels constituting learning data affect the semantic segmentation of railroad tunnels through deep learning. As a result of the parametric study, the similar size of the tunnels used for learning and testing, the higher segmentation accuracy, and the better results when learning through a double-track tunnel than a single-line tunnel. In addition, when the training data is composed of two or more tunnels, overall accuracy (OA) and mean intersection over union (MIoU) increased by 10% to 50%, it has been confirmed that various configurations of learning data can contribute to efficient learning.

• Journal of Korea Society of Industrial Information Systems
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• v.26 no.6
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• pp.97-118
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• 2021

This study empirically examines the effect of the psychological empowerment of airline cabin crews on customer-focused job performance attitude, service behavior by CSM, and service behavior beyond CSM. The research model and associated hypotheses were verified with the structural equation model. The findings of the study reveal that psychological empowerment has a effect on customer-focused job performance attitude and service behavior by CSM, but no effect on service behavior beyond CSM. And it is also shown that customer-focused job performance attitude has an effect on service behavior by CSM but no effect on service behavior beyond CSM. In addition, customer-focused job performance attitude shows a mediating effect between psychological empowerment and service behavior by CSM. On the other hand, it is analyzed that there is no mediating effect between psychological empowerment and service behavior beyond CSM. This study implies that the psychological empowerment and customer-focused job performance attitude of cabin crews are important at point of contact with customers to improve service quality, and psychological empowerment reinforces service behavior by CSM on the premise of customer-focused job performance attitude.

• Journal of Korean Society of Forest Science
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• v.111 no.2
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• pp.319-329
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• 2022

Using the structural equation model (SEM), this paper investigated the relations between the recognition of forest ecosystem services and the pro-environmental behavior with personal environmental commitment and environmental consciousness. The research data was collected from April 11 to 21, 2019, as an online survey by residents in Korea. 425(91.4%) of the total 465 copies were used as final analysis data, excluding insincere responses. Results showed that most respondents recognized forest ecosystem services as positive and recognition of forest ecosystem services has a positive impact on both environmental commitment and environmental consciousness. Moreover, cultural services positively affected both constructs more than supply and control services. The most significant total effect was the path of 'cultural services-environmental commitment-pro-environmental behavior'. Environmental commitment is more effective in inducing the behavior than environmental consciousness to those who consider forest ecosystem services significant. Even if forest ecosystem services are recognized as important, those with experience of commitment to the natural environment would have more intention of pro-environmental behavior. In conclusion, this study is meaningful in that it identified the hypothesized path relationship between the recognition of forest ecosystem services and the pro-environmental behavior and analyzed the antecedent factors.

• Science of Emotion and Sensibility
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• v.25 no.3
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• pp.15-32
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• 2022

This study seeks to clarify the mechanisms of anthropomorphism and positive user experience. This study adopts the "computers are social actors" (CASA) paradigm to verify the causal relationship between social response and anthropomorphism and correctly explicate this paradigm. The intimacy-forming and anthropomorphizing effects of deep self-disclosure in interpersonal relationships were replicated in relationships between humans and conversational agents to induce both social response and anthropomorphism. Then, the mediating effect of intimacy on the anthropomorphizing effect of deep self-disclosure was explored with psychological models that revealed the causal relationships between social connections, including intimacy and anthropomorphism. Furthermore, we explored how intimacy and anthropomorphism trigger positive user experiences. The results demonstrated that the deeper the self-disclosure depth was, the more intimate and humanly the agent was perceived and the more positive the user experience was. In addition, the effect of self-disclosure depth on anthropomorphism and positive user experience was completely mediated by intimacy. This means that when using a computer with interpersonal characteristics, people anthropomorphize it and have a positive experience because people react socially to objects with social cues. This study bridges the gap between the CASA paradigm and anthropomorphism research, suggesting the possibility of psychological explanations for the principle of human-computer interactions. In addition, it explicates the mechanism of anthropomorphism and positive user experience, emphasizing the importance of social response-that is, intimacy.

• Journal of the Korea Society for Simulation
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• v.19 no.3
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• pp.37-43
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• 2010

In field, one can observe without difficulties that two flocks are intersected or combined with each other. For example, a fish flock in a stream separates into two part by obstacles (e.g. stone) and rejoins behind the obstacles. The dynamics of two flocks guided by their leader were studied in the situation where the flocks cross each other with a crossing angle, ${\theta}$, between their moving directions. Each leader is unaffected by its flock members whereas each member is influenced by its leader and other members. To understand the dynamics, I investigated the order parameter, ${\phi}$, defined by the absolute value of the average unit velocity of the flocks' members. When the two flocks were encountered, the first peak in ${\phi}$ was appeared due to the breaking of the flocks' momentum balance. When the flocks began to separate, the second peak in ${\phi}$ was observed. Subsequently, erratic peaks were emerged by some individuals that were delayed to rejoin their flock. The amplitude of the two peaks, $d_1$ (first) and $d_2$ (second), were measured. Interestingly, they exhibited a synchronized behavior for different ${\theta}$. This simulation model can be a useful tool to explore animal behavior and to develop multi-agent robot systems.

• Korean Journal of Social Welfare Studies
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• v.43 no.2
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• pp.207-233
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• 2012

The purpose of this study is to understand direct and indirect impact and the paths of community participation and social capital, which affect improvement of single mother's community participation factors, social capital, and empowerment. To accomplish this purpose structural relationships between single mother's community participation factors, social capital and empowerment have been analyzed. For the analysis 420 single mothers, who had participated various types of communities, were surveyed and structural equation modeling had been used and optical theory structure model(χ²=86.851, df=28, GFI=.958, CFI=.944), which explains the structural relationship among the factors, had been chosen. From the result, first, there was differences between empowerment and community participation levels, which is single mothers' community participation factors, of the impact on social capital and empowerment. Empowerment level of community, which was mediated by community participation level and social capital, affected empowerment, in the other hand, community participation level affected empowerment more directly than the impact of social capital. Second, single mothers' community participation factor affected more improvement of empowerment when it mediated by the accumulation of social capital. Third, single mothers' social capital directly affected the most improvement of empowerment. Based on the fact the implications of the study were presented.

• Journal of the Korean Geotechnical Society
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• v.23 no.1
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• pp.23-37
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• 2007

Recently a concept of pile-tip enlarged PHC pile (Ext-PHC pile), for use in the auger-drilled construction method, has been developed and is being implemented in practice. A series of field axial load tests on both PHC and Ext-PHC piles were conducted at an experimental site. In addition, a parametric study on a number of influencing factors was made using a validated finite element model. The field axial load tests indicated an enhanced load-settlement characteristics for the Ext-PHC piles compared with the PHC piles, giving approximately 50% increase in the end bearing capacity. Also found in the results of the parametric study was that the increase in the end bearing capacity of Ext-PHC piles slightly varies with the mechanical properties of supporting ground as well as pile length, in the range of 1.25 to 1.4 time that of PHC. Overall, the results of the field tests as well as the numerical study confirmed that the end bearing capacity of PHC pile can be improved by the concept of.Ext-PHC pile.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.8 no.2
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• pp.89-102
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• 2018

With the development of mobile technology, asset management on the Internet have also developed a lot. Drawing on Technology Acceptance Model, this study examines YUEBAO deployment to model consumers' purchase intention to use financial products offered online. In this study, we hypothesized that the characteristics of online asset management product will affect the purchase intention through perceived usefulness and conduct empirical analysis on Chinese consumers. In the study model, the independent variables were considered to include individual involvement, experience, product protection, corporate credibility, convenience, mobility, and familiarity. In addition, the parameters constitute the usefulness, and the dependent variable is the purchase. The results are as follows. First, YUEBAO's complementarity, corporate credibility, convenience, and familiarity have a significant influence on YUEBAO's usefulness. Second, The YUEBAO's usefulness has a noticeable effect on the purchase intention. To perceive the high usefulness, the practicality strategy of enhancing the protection property, corporate reliability, convenience and familiarity of the online asset management product is needed. The study of consumer purchase behavior and consumer purchase intention of online wealth management products is very valuable for academic and practical work.