• Title/Summary/Keyword: 망상

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멕시코 로얄 은광산 잠재성 평가

  • Heo, Cheol-Ho;Kim, Ui-Jun
    • 한국지구과학회:학술대회논문집
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    • 2010.04a
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    • pp.108-109
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    • 2010
  • IMPACT Silver 주식회사는 Zacualpan 프로젝트의 Royal Mines(이하 로얄 광산)을 인수했다. $124.5\;km^2$에 해당하는 지역의 소유권은 두 개의 멕시코 사기업으로부터 가행중인 광산의 채굴권 구입과 운영 중인 기반시설의 임대를 조건으로 한다. 프로젝트 지역은 멕시코시티로부터 남서방향으로 100 km와 Taxco Silver 광산으로부터 북서방향으로 25 km 떨어진 지점에 위치한다. 기반시설은 비포장 도로, 충분한 전력과 물의 공급 및 숙련공들을 갖추어 우수한 평가를 받고 있다. 소유권은 멕시코인의 개인소유 하에서 무한한 매장량 혹은 자원량을 갖고 운영된 채광과 가공시설을 인수하는 것이다. 소유권 지역을 대상으로 한 IMPACT Silver사의 주 탐사목적은 이미 알려진 광화대의 확장을 위한 잠재성 평가와 다른 지역에서 신규 광상의 유망지역을 발견하는 것이다. Zacualpan 프로젝트의 로얄 광산은 남동 Guerrero terrane의 북부에 위치한다. Teloloapan subterrane은 주로 저변성 녹색편암상으로 구성된 쥬라기 후기에서 백악기 초기의 화산성 퇴적층으로 구성된다. 대부분의 유망지역은 Lower Villa de Ayala층의 중성 내지 염기성 화산성 쇄설암을 모암으로 한다. 다상의 변성작용은 지역 전반에 걸쳐 나타나고, Zacualpan 광산지역에서 수반되는 광화작용을 규제한다. Zacualpan 광산지역은 Sierra Madre del Sur로 알려진 유망 광화대에 해당한다. 이 지역은 화산성 괴상 황화광상과 천열수 맥상광상이 우세하다. 대부분의 천열수 광화작용은 3.2-3.8억 년 전 마그마의 생성이 활발한 판구조 체제 동안 발생하였다. 역사적으로 가장 주요한 지역은 Lipton Vein이다. 현재 Zacualpan 지구에서 채광량은 은 200-500 g/t 정도로 보고되고 있다. 일부 지역은 고품위 은 광화작용(은 1,000 g/t 이상)을 수반하고 있으며, 이는 탐사의 주 타겟이 되고 있다. Zacualpan에서 은 광화작용은 은이 부화된 중유황 천열수 맥상광상으로 상당히 유명하다. Fresnillo, Pachuca 및 Taxco 광산을 포함한 멕시코 소유의 대규모의 잘 알려진 광산들이 이에 해당한다. 이러한 광산들은 부산물로서 금, 아연, 연이 생산된다. 이러한 광상들은 맥상과 각력상 및 산점상 또는 망상세맥의 형태로 산출된다. 광화작용은 석영과 탄산염 맥 내에 주로 황철석과 다양한 섬아연석, 방연석, 은 혹은 금 광물들을 수반한다. 경제성을 갖는 광화작용의 수직적인 연장은 평균적으로 대략 300 m이고, 멕시코 중부에 위치한 Fresnillo의 광화작용은 100 m에서 960 m의 연장을 갖는 것으로 알려져 있다. 아주 오랫동안 Zacualpan에서 광산관계자의 관측과 IMPACT Silver에서 최근 작업의 결과를 토대로, Zacualpan 광산지역의 탐사모델은 새로운 광상의 탐사를 위한 가이드로서 개발되었다. Zacualpan 광산지역에서 가장 높은 경제성을 갖는 광화작용은 북서와 남북방향의 맥 구조를 따라 수반된다. 이러한 맥 구조들은 종종 이 지역을 가로질러 수 km까지 추적되지만, 경제성을 갖는 광화작용은 맥 구조를 따라서 구조적으로 유리한 지역에서 부광대를 형성한다. 부광대를 형성하기 위한 가장 유리한 구조적 지역은 북서와 남북방향으로 발달한 맥 구조들이 교차하는 지역이다. 지난 30년간 채광된 주요 부광대는 폭이 2-6 m 이고 수평연장은 30-150 m 그리고 수직연장은 230-300 m에 이른다. 가장 높은 생산량을 보이는 부광대는 남북방향의 이차 맥들이 Guadalupe 광산의 Lipton 맥을 가로지르는 지역에서 발달한다. 남동쪽으로 현재 Compadres 광산의 Silver Shoot No. 1으로부터 고품위 은을 생산하는 지역은 북서방향의 San Agustin 맥이 북향의 Cometa Navideno 맥에 의해 절단되는 지역에서 산출한다. 모암은 광화작용을 규제하는 또 다른 중요한 요소이다. 광산지역에서 경제성을 갖는 모든 광화작용은 중성 내지 염기성 화산암 특히 안산암과 관련 모암에 배태된다. 부광대가 셰일 혹은 편암으로 전이되는 지역에서, 맥들은 소규모의 세맥으로 나뉘어 진다. Zacualpan의 전형적인 천열수 광상에서 부광대는 상부로 가면서 은의 함량이 증가하고, 하부로 가면서 연 아연의 함량이 증가하는 수직적 대상을 보인다. 금의 함량 변화는 보다 예측이 어려우나 상당히 중요하다. Zacualpan 광산지역의 탐사모델에 사용된 토양 채취, 정밀지도제작, 트렌치 및 시추탐광은 현재 IMPACT Silver사가 이 지역을 대상으로 한 가장 효율적인 탐사방법으로 입증되었다. Zacualpan 프로젝트의 로얄 광산은 하루 500 톤을 제련하는 기반시설과 수반된 채굴권을 갖는 가행 광산들을 포함한다. 현재 IMPACT Silver사는 두 곳의 타겟 지역에서 정밀지도제작, 토양 및 암석 채취, 12공 총 1866 m의 시추탐광에 의한 사전조사로 구성된 4 단계 탐사를 수행했다. 암석 1,953개, 토양 1,631 개, 389 개의 시추코어 시료가 채집되고 분석되었다. 이러한 작업은 추가탐사를 요구하는 수많은 유망 광화대를 규명했다. Compadres 광산에서 현재 가행중인 지하갱 시료는 레벨 1에서 0.9 m의 폭을 갖는 광체에서 은 680 g/t과 금 0.3 g/t, 레벨 3에서 1.67 m의 폭을 갖는 광체에서 은 12,591 g/t과 금 12.07 g/t의 품위를 갖는 것으로 나타났다. 레벨 1에서 3까지 2-3 m의 폭과 30-40 m 연장으로 채광되었다. 시추탐광은 고품위를 갖는 몇몇의 중첩된 맥을 발견했다. Compadres 광산에서 남동방향으로 200 m지점에 위치한 Soledad 지역에서 5 개의 시추공으로부터 동일 맥 시스템이 발견되었고, 고품위 부광대의 상부로 간주되는 몇몇 중요 지점이 발견되었다. 초기 단계의 탐사는 유망 시추탐광 지역인 중간정도 내지 고품위 유망 광화대를 규명했다.

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EFFECT OF DECALCIFIED FREEZE-DRIED ALLOGENEIC BONE GRAFT(DFDB) ON THE JAW DEFECTS AFTER CYST ENUCLEATION (낭종 적출후 악골 결손부 치유에 관한 동종골 이식 효과에 관한 연구)

  • Lee, Dong-Keun;Min, Seung-Ki;Kwon, Kyung-Hwan;Sung, Hun-Mo;Park, Hwa-Kyu;Kang, Mun-Jeong;Sin, Ki-Young
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.21 no.4
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    • pp.360-365
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    • 1999
  • This study was aimed to suggest to better treatment method of jaw cyst that the maximum diameter was wider than 3cm, using different treatment and clinical and radiographic result. We divided the 60 patients into three groups, group A(20 patients) were treated with cyst enucleation and Decalcified Freeze-Dried Allogeneic Bone(DFDB) graft, group B(20 patients) were treated with cyst enucleation and autogenous bone graft, group C(20 patients) were treated with only cyst enucleation. Each group was evaluated with panoramic radiograph and clinical sign & symptom at pre-op and post-op(immediate, 6, 12, 24, 36 month). Bone density was evaluated with disital densitometer. The result was as follows : 1. Post-Op infection was higher in group C(4 pts.) than in group A(1 pt.) and B(1 pt.) 2. Post-Op gingival recession was higher in group C(3 Pts.) than in group A(1 pt.) and B(1 pt.) 3. Anatomic distortion was higher in group C(3 Pt.) than in group A(1 Pt.), and B(1 pt.) 4. Reoperation was done in two patients who were in group C 5. There were donor site morbidity in two patients 6. There was no significant difference between group A and B in their bony density in their follow up period(p>0.05). 7. There were significant differences between group A, B and group C in their bony density until post-op 24 months but a little differences at post-op 36 months(P<0.01)

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A Case of Bronchus-Associated Lymphoid Tissue(BALT) Lymphoma in the Lung of the Patient with Primary Sj$\ddot{o}$gren's Syndrome (원발성 쇼그렌 증후군(Primary Sj$\ddot{o}$gren's Syndrome) 환자에서 발생한 Bronchus-Associated Lymphoid Tissue(BALT) 림프종 1례)

  • Kang, Min-Jong;Lee, Jae-Myung;Lee, Seung-Joon;Son, Jee-Woong;Kim, Dong-Gyu;Lee, Myung-Goo;Hyun, In-Gyu;Jung, Ki-Suck
    • Tuberculosis and Respiratory Diseases
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    • v.52 no.2
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    • pp.179-185
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    • 2002
  • A bronchus-associated lymphoid tissue(BALT) lymphoma of the lung is a rare disorder of patients with Sj$\ddot{o}$gren's syndrome. A 49-year-old woman was admitted for an evaluation of exertional dyspnea and general weakness which had persisted for two years. The patient had suffered from dry mouth and dry eyes for five years. The physical examinations showed a coarse breath sound with inspiratory crackles on the whole lung field, particularly on the both basal lungs. The laboratory data disclosed high titers of anti-nuclear antibodies, and anti-SSA (Ro), and anti-SSB (La) antibodies. Chest radiographs demonstrated the presence of bilateral, diffuse, reticulonodular densities in both lungs. Thin-section CT scans showed diffusely distributed mosaic pattern of an inhomogeneous attenuation extending over the entire lung zone. The histological findings from an open-lung biopsy specimen revealed an accumulation of lymphoid cells around the bronchioles and an extension of malignant lymphoma cells from the bronchiolar epithelium toward the alveolar space. Immunohistochemically, the neoplastic cells reacted positively to the CD 20 antigen and were focally positive for the UCHL 1 antigen. The histological diagnosis was consistent with a low grade marginal zone B-cell lymphoma originating in the BALT. Here, we present a case of a histologically proven BALT lymphoma of the lung in a patient with primary Sj$\ddot{o}$gren's Syndrome.

Experimental Studies on Lead Toxicity in Domestic Cats 1. Symptomatology and Diagnostic Laboratory Parameters (고양이의 납중독에 관한 실험적 연구 1. 임상증상 및 실험실적 평가)

  • Hong Soon-Ho;Han Hong-Ryul
    • Journal of Veterinary Clinics
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    • v.10 no.1
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    • pp.111-130
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    • 1993
  • Lead toxicity was evaluated in forty-five cats on a balanced diet, Treated with 0(control), 10, 100(low), 1, 000, 2, 000, and 4, 000(high) ppm of lead acetate orally on a body weight basis. The objectives were to establish toxic dosage level of leaf in cats, to characterize changes in behavior and clinical pathology, and to demonstrate what blood lead concentrations correlate with the known dosages of lead. Some high dose cats showed projectile vomiting, hyperactivity, and seizures. The growth rates did not appear to be altered in any of the dosed groups. Normal blood lead concentration in cats were lower than that of humans, dogs, and cattle. Blood lead concentrations of 3 to 20$\mu\textrm{g}$/100$m\ell$ could be termed a 'subclinical' range in the cat. Clinical lead toxicity in cats may have blood lead concentrations ranging 20 to 120$\mu\textrm{g}$/100$m\ell$. Zinc protoporphyrin concentrations were proportional to lead dosages and a significant ZPP elevation, greater than 50$\mu\textrm{g}$/100$m\ell$, may be indicative of clinical lead toxicity. The enzyme aminolevulinic acid dehydratase showed an inverss dose response relationship for all lead dosages and a significant ZPP elevation, greater than 50$\mu\textrm{g}$/100$m\ell$, may be indicative of clinical lead toxicity. The enzyme aminolevulinic acid dehydratase showed an inverse dose response relationship for all lead dosages and appears to be a good indicator of lead exposure in cats. Urinary aminolevuliruc acid concentrations generally increased with lead dosage, but individual values varied. Hair lead concentrations rose proportionately to lead dosages. Lead at least in high doses appears to inhibit chemotactic activity of polymorphonuclear cells and monocytes. No consistent dose response relationships were observed in hemoglobin, RBC, WBC, neutrophil, lymphocyte, monocyte, and eosinophil counts. There were no consistent dose related changes in total protein, plasma protein, BUN, and ALT values. Reticulocyte counts did not increase significantly in most lead dosage levels, and are probably of little value in diagnosing lead toxicity in cats. The fact that no significant changes were found in nerve conduction velocities may support that there was no segmental demyelination resulting from lead ingestion. The lethal dose in cats appear to range from 60 to 150mg/kg body weight. A reliable diagnosis of lead poisoning can be made utilizing blood lead, ZPP, and ALAD, and hair lead.

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Immunohistoehemical Observation on the Antigens Inducing IgG and IgM Antibodies against Sparganum (IgG와 IgM 항체를 유도하는 sparganum의 항원에 관한 면역조직화학적 및 전기영동에 의한 연구)

  • 김창환;최완성
    • Parasites, Hosts and Diseases
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    • v.29 no.4
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    • pp.339-354
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    • 1991
  • Localization and characterization of the antigenic components of sparganum which induced IgG and IsM antibodies in the host were studied by immunohistochemical techniques and SDS-PAGT and Western blotting. The antigen recognized by IgG antibody of rats or mice which were immunised by infection or injection of crude extracts of metacestodes of Spirometra erinacei, was located in the parenchyme of sparganum, especially at the cortex and around the calcareous corpuscles. The immunoreaction was demonstrated not only in the encysted fibrous wall of host but around the arterioles or venules in the connective tissue of host. The antigen recognized by IgM antibody of rats or mice was also observed in the parenchyme of sparganum and in the connective tissue of host. By 5∼20% gradient SDS-PAGE and EIBT, we detected antigenic components by IgG and 1gG antibodies of the rat or mouse immunized by infection or injection of crude extract of spargana. Twenty-three antigenic bands from crude extracts of spargana were recognized by IgG antibody and 15 components by IgM antibody of immunized rats. Out of the bands recognized by IgG and IgM antibodies, 15 were cross-reacted each other. Twenty components of eBlcretory-secretory proteins from spargana were recognized by IgG, and 5 components by IgM antibody of immunized rats. By IgG and IgM antibodies of immunized mice, 16 components of crude extracts were recognized by IgG antibody and 9 components by IgM antibody. Twenty components of excretory-secretory preparation were recognized by IgG antibody and 5 components by IgM antibody. Thirteen components of crude extracts were cross-reacted by IgG antibody of rats and mice.

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Sedimentary Environmental Change and the Formation Age of the Damyang Wetland, Southwestern Korea (한국 남서부 담양습지의 퇴적환경 변화와 형성시기 연구)

  • Shin, Seungwon;Kim, Jin-Cheol;Yi, Sangheon;Lee, Jin-Young;Choi, Taejin;Kim, Jong-Sun;Roh, Yul;Huh, Min;Cho, Hyeongseong
    • Journal of the Korean earth science society
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    • v.42 no.1
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    • pp.39-54
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    • 2021
  • Damyang Wetland, a riverine wetland, has been designated as the first wetland protection area in South Korea and is a candidate area for the Mudeungsan Area UNESCO Global Geopark. The Damyang Wetland area is the upstream part of the Yeongsan River and is now a relatively wide plain. To reconstruct the sedimentary environment around the Damyang Wetland, core samples were obtained, and sedimentary facies analysis, AMS and OSL age dataings, grain size, and geochemical analyses were carried out. In addition, comprehensive sedimentary environment changes were reconstructed using previous core data obtained from this wetland area. In the Yeongsan River upstream area, where the Damyang Wetland is located, fluvial terrace deposits formed during the late Pleistocene are distributed in an area relatively far from the river. As a gravel layer is widely distributed throughout the plains, Holocene sediments were likely deposited in a braided river environment when the sea level stabilized after the middle Holocene. Then, as the sedimentary environment changed from a braided river to a meandering river, the influx of sand-dominated sediments increased, and a floodplain environment was formed around the river. In addition, based on the pollen data, it is inferred that the climate was warm and humid around 6,000 years ago, with wetland deposits forming afterward. The the trench survey results of the river area around the Damyang Wetland show that a well-rounded gravel layer occurs in the lower part, covered by the sand layer. The Damyang Wetland was likely formed after the construction of Damyang Lake in the 1970s, as muddy sediments were deposited on the sand layer.

The Style and Cultural Significance of Film Color White (영화색채 하양의 활용 양상과 문화적 의미)

  • Kim, Jong-Guk
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.4
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    • pp.187-198
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    • 2020
  • With the cultural background of whiteness I did examine the universal meaning of absolute good, the special of psychosis, and the fantastic of femininity and memory/record. As an example I analyzed the symbolic meaning of white used in Korean films. Unconditional goodness, white as a generality: White color in all the films of good-evil confrontation falls into this category. The most obvious and the simplest configuration are the black-white dichotomy. In Nameless Gangster: Rules of Time(2011), The Merciless(2016), Asura: The City of Madness(2016) and The Bad Guys: Reign of Chaos(2019), white is the absolute good but it is not limited to a fair key figure. Paradoxically, black is not given only to the side of absolute evil. White is used to be a flexible visual device that reflects the socio-political situation without changing the meaning of the general good. Psychosis and pills, white as a peculiarity: The visual function that emphasizes sado-masochism in the absolute good and the universal symbol of white extends to psychotic specificities such as hysteria. In all the films creating horror, white symbolizes the mentally disabled and the pill for healing. Femininity and haunted white: White of absolute good is expressed by the socio-cultural tendency of femininity and the black-white contrast of vision is applied to the gender difference. In general the women's sexuality is emphasized in color red, but white is arranged in the background. In TaeGukGi: Brotherhood Of War(2004), 71: Into The Fire(2010), My Way(2011), The Front Line(2011), Roaring Currents(2014), Northern Limit Line(2015), The Battle: Roar to Victory(2019) and Battle of Jangsari(2019), white given to female figures sticks to the traditional femininity such as motherhood, sacrifice and weakness. The concept of specters is applied to desires, memories/records, history, fantasy, virtual/reality and social media images. The film history capturing to list memories and moments brings up the specters of socio-political genealogy. Most of films aiming for socio-political change are its examples and white constituting Mise-en-scene records to remember a historical event in Peppermint Candy(2000), The Attorney(2013) and A Taxi Driver(2017).

Quality Characteristics of Cuttlefish Inky Tofu Prepared with Various Coagulants (응고제에 따른 오징어 먹물 두부의 품질 특성)

  • Park, Eo-Jin;An, Sang-Hee
    • Journal of the Korean Society of Food Culture
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    • v.21 no.6
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    • pp.653-660
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    • 2006
  • Some quality characteristics of tofu prepared with cuttlefish ink were investigated to study the effects of various of coagulants. Each concentration of coagulant was determined as 0.2% of GDL, 0.3# of $MgCl_2$, 1%^ of $CaCl_2$, 1.5% of $CaSO_4$ and 0.6% D-gluconic acid calcium by pre-experiment. Also, the optimum concentration of added cuttlefish ink was chosen as 3%(diluted in twenty times). The yield of inky tofu prepared with GDL as coagulant was the highest. According to prepared with $MgCl_2$ was the highest. The result of microstructure was examined by SEM, the particles of inky tofu coagulated with GDL and D-gluconic acid calcium were small and uniformity. In overall acceptability of sensory properties, inky tofu coagulated with GDL was the highest in score. In the color of inky tofu, L value and a value were the highest coagulated with GDL, but that coagulated with $CaCl_2$ had the highest b value. In the texture properties of inky tofu, hardness, gumminess and brittleness were the highest coagulated with D-gluconic acid calcium. A positive correlation was observed between the pH of tofu whey and acidity. Sensory properties of roasted nutty flavor, hardness, cohesiveness and springiness were positively correlated with the acceptability.

CLINICAL CHARACTERISTICS OF CHILD AND ADOLESCENT PSYCHIATRIC INPATIENTS WITH MOOD DISORDER (입원한 기분장애 소아청소년의 임상특성 - 주요 우울증과 양극성장애의 우울삽화 비교를 중심으로 -)

  • Cho, Su-Chul;Paik, Ki-Chung;Lee, Kyung-Kyu;Kim, Hyun-Woo;Hong, Kang-E;Lim, Myung-Ho
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.11 no.2
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    • pp.209-220
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    • 2000
  • The purpose of this study is to find out the characteristics of depressive episode about major depression and bipolar disorder in child and adolescent. The subjects of this study were 34 major depression patients and 17 bipolar disorder patients hospitalized at child and adolescent psychiatry in OO university children's hospital from 1st March 1993 to 31st October 1999. The method of this study is to review socio-demographic characteristics, diagnostic classification, chief problems and symptoms at admission, frequency of symptoms, maternal pregnancy problem history, childhood developmental history, coexisting psychiatric disorders, family psychopathology and family history and therapeutic response through their chart. 1) The ratio of male was higher than that of female in major depressive disorder while they are similar in manic episode, bipolar disorder. 2) Average onset age of bipolar disorder was 14 years 1 month and it was 12 years 8 months in the case of major depression As a result, average onset age of major depression is lower than that of bipolar disorder. 3) The patients complained of vegetative symptoms than somatic symptoms in both bipolar disorder and depressive disorder. Also, the cases of major depression developed more suicide idea symptom while the case of bipolar disorder developed more aggressive symptoms. In the respect of psychotic symptoms, delusion was more frequently shown in major depression, but halucination was more often shown in bipolar disorder. 4) Anxiety disorder coexisted most frequently in two groups. And there coexisted symptoms such as somartoform disorder, mental retardation and personality disorder in both cases. 5) The influence of family loading was remarkable in both cases. Above all, the development of major depression had to do with child abuse history and inappropriate care of family. It is apparent that there are distinctive differences between major depression and bipolar disorder in child and adolescent through the study, just as in adult cases. Therefore the differences of clinical characteristics between two disorders is founded in coexisting disorders and clinical symptoms including onset age, somatic symptoms and vegetative symptoms.

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Clinicopathologic features of Acute Interstitial Pneumonia (급성 간질성 폐렴의 임상적 고찰)

  • Shim, Jae-Jeong;Park, Sang-Muyn;Lee, Sang-Hwa;Lee, Jin-Gu;Cho, Jae-Yun;Song, Gwan-Gyu;In, Kwang-Ho;Yoo, Se-Hwa;Kang, Kyung-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.42 no.1
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    • pp.58-66
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    • 1995
  • Background: Acute interstitial pneumonia is a relatively rare form of interstitial pneumonia, since the vast majority of interstitial pneumonia have a more chronic course. It corresponds to the lesion described by Hamman and Rich, as Hamman-Rich disease in 1944. Another name in the clinical literature is accelerated interstitial pneumonia, idiopathic acute respiratory distress syndrome (idiopathic ARDS), and the organizing stage of diffuse alveolar damage. Acute interstitial pneumonia differs from chronic interstitial pneumonia by clinical and pathologic features. Clinically, this disease is characterized by a sudden onset and a rapid course, and reversible disease. Method and Purpose: Five cases of pathologically proven acute interstitial pneumonia were retrospectively studied to define the clinical, radiologic, and pathologic features. Results: 1) The five cases ranged in age from 31 to 77 years old. The onset of illness was acute in all patients, it began with viral-like prodrome 6~40 days prior to shortness of breath, and respiratory failure eventually developed in all patients. In 2 cases, generalized skin rash was accompanied with flu-like symptoms. Etiologic agent could not be identified in any case. 2) All patients had leukocytosis and severe hypoxemia. Pulmonary function test of 3 available cases shows restrictive ventilatory defect, and one survived patient(case 5) has a complete improvement of pulmonary function after dismissal. 3) Diffuse bilateral chest infiltrates were present radiologically. Theses were the ground-glass, consolidation, and reticular densities without honeycomb fibrosis in all patients. The pathologic abnormalities were the presence of increased numbers of macrophages and the formation of hyaline membranes within alveolar spaces. There was also interstitial thickening with edema, proliferation of immature fibroblast, and hyperplasia of type II pneumocyte. In the survived patient(case5), pathologic findings were relatively early stage of acute interstitial pneumonia, such as hyaline membrane with mild interstitial fibrosis. 4) Of the 5 patients, four patients died of respiratory failure 14~90 days after onset of first symptom, and one survived and recovered in symptoms, chest X ray, and pulmonary function test Conclusion: These results emphasize that acute interstitial pneumonia is clinically, radiologically, and pathologically distinct form of interstitial pneumonia and should be separated from the group of chronic interstitial pneumonia. Further studies will be needed to evaluate the pathogenesis and the treatment of acute interstitial pneumonia.

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