• 제목/요약/키워드: 라이락

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Effect of salt additives on structure of biodegradable PLGA nanofibers (PLGA 나노섬유의 구조에 미치는 첨가제의 영향)

  • You, Young;Park, Won-Ho;Min, Byung-Moo;Lee, Seung-Jin
    • Proceedings of the Korean Fiber Society Conference
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    • 2003.04a
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    • pp.218-220
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    • 2003
  • 지방족 폴리에스터계 고분자인 폴리락타이드 (polylactide, PLA), 폴리글리콜라이드 (polyglycolide, PGA) 및 이들의 공중합체인 락타이드-글라이콜라이드 공중합체 (PLGA)는 생체 친화성이고 생분해성이며 물리적 강도가 우수하고 쉽게 성형할 수 있다. 그리고, 전기방사는 수 마이크로에서 수십 나노크기의 지름을 가지는 초극세 섬유인 나노섬유의 제조 기술로서 기존의 섬유 방사방식과는 근본적으로 다른 새로운 방사기술로 산업적인 융용 가능성이 무한한 미래지향적 기술로 최근 주목을 받고 있다. (중략)

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Biodegradation behaviors of PLGA nanofibers with different morphology (PLGA계 나노섬유의 형태에 따른 생분해거동)

  • You, Young;Park, Won-Ho;Min, Byung-Moo;Lee, Seung-Jin
    • Proceedings of the Korean Fiber Society Conference
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    • 2003.10b
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    • pp.49-51
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    • 2003
  • 지방족 폴리에스터계 고분자인 폴리락타이드 (polylaccde, PLA), 폴리글리콜라이드 (polyglycolide, PCA) 및 이들의 공중합체인 락타이드-글리콜라이드 공중합체 (PLCA)는 생체친화성이고 생분해성이며 물리적 강도가 우수하고 쉽게 성형할 수 있다. 그리고, 전기방사는 수 마이크로에서 수십 나노크기의 지름을 가지는 초극세 섬유인 나노섬유의 제조기술로서 기존의 섬유 방사방식과는 근본적으로 다른 새로운 방사기술로 산업적인 웅용 가능성이 무한한 미래지향적 기술로 최근 주목을 받고 있다. (중략)

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Preparation and Release Behavior of Methoxy poly(ethylene glycol)- poly(L-lactide-co-glycolide) Wafer Containing Albumin (알부민을 함유한 메톡시 폴리(에틸렌 글리콜)- 폴리(L-락타이드-co-글리콜라이드) 웨이퍼의 제조 및 방출거동)

  • 서광수;김문석;김경자;조선행;이해방;강길선
    • Polymer(Korea)
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    • v.28 no.4
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    • pp.328-334
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    • 2004
  • A series of methoxy poly(ethylene glycol) (MPEG)-poly(L-lactide-co-glycolide) (PLGA) diblock copolymers were synthesized by ring-opening polymerization of L-lactide and glycolide with carbitol (134 g/mole) or different molecular weights of MPEG (550, 2000, and 5000 g/mole) as an initiator in presence of Sn(Oct)$_2$. The properties of diblock copolymers were characterized by using $^1$H-NMR, GPC, and XRD. After uniform mixing of block copolymers and 1% albumin bovine-fluorescein isothiocyanate(FITC-BSA) with a freeze miller, the wafers loaded FITC-BSA were fabricated by using a mold with a dimensions of 3 mm${\times}$1mm diameter. The release profiles of FITC-BSA and the pH changes of wafer were examined using pH 7.4 PBS for 30 days at 37$^{\circ}C$. The release profiles of albumin showed fast initial burst as the molecular weights of MPEG increased. As a result of this study, the release behavior of BSA was controlled with introducing MPEG in the block copolymers.

Application Framework Implementation of Iris Recognition System (홍채 인식 시스템의 응용 프레임워크 구현)

  • Chun, Jin-Ho;Kim, Jai-Hoon;Han, Kyung-Hee
    • Proceedings of the Korea Information Processing Society Conference
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    • 2010.11a
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    • pp.1104-1107
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    • 2010
  • 홍채 인식 시스템의 응용 프레임워크는 홍채 인식기 모듈을 컴퓨터에 연결할 때 사용되는 USB 호스트 콘트롤러 드라이버와 응용 프로그램 사이에서 둘을 제어하는 스탠다드 라이브러리를 제공한다. 본 논문에서는 스탠다드 라이브러리 설계와 구현을 설명하고 있다. 스탠다드 라이브러리는 표준 호출규약을 지키므로 응용 프로그램은 다양한 언어로 작성할 수 있다. 또한, 기존의 폴링 방식으로 구현된 스탠다드 라이브러리를 콜백을 이용하여 구현함으로써 네트워크를 통해 많은 사람들이 동시에 홍채 인식기를 사용할 때 리소스 사용을 경감할 수 있는 장점이 있다.

Preparation of Poly(Dt-lactide-co-glycolide) Nanoparticles by PEG-PPG Diblock Copolymer (PEG-PPG 블록 공중합체를 이용한 폴리(DL-락타이드-co-글리콜라이드) 나노입자의 제조)

  • 정택규;오유미;신병철
    • Polymer(Korea)
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    • v.27 no.4
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    • pp.370-376
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    • 2003
  • Poly(DL-lactide-co-glycolide) nanoparticles were prepared by the modified spontaneous emulsification solvent diffusion method. Polymer solution was prepared by two water-soluble organic solvents, such as ethanol and acetone. Because of its biocompatible nature, PEG-PPG diblock copolymer was used as surfactant and stabilizer. The influence of several preparative variables on the nanoparticle formation, such as type and concentration of stabilizing agent, stirring methods, water/oil phase ratio and polymer concentration were investigated in order to control and optimize the process. After preparation of nanoparticles, particle size and distribution were evaluated by the light scattering particle analyzer. As results, the particle size was 50-200 nm and dispersibility was monodisperse. It was found that the appropriate selections of binary solvent mixtures and polymeric concentrations in both organic and aqueous phases could provide a good yield and favorable physical properties of PLGA nanoparticles.

Formulation and Characterization of Lipase Loaded Poly(D,L - lactide-co-glycolide) Nanoparticles (리파아제가 함입된 락타이드-글리콜라이드 공중합체 나노입자의 제조 및 특성)

  • Kim, Beom-Su;ZEROUAL, Y;Lee, Kang-Min
    • Polymer(Korea)
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    • v.31 no.1
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    • pp.20-24
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    • 2007
  • The preservation of biological activity of protein drugs in formulation is still a major challenge for successful drug delivery. Lipase was encapsulated in poly (D,L-lactide- co-glycolide) PLGA nano-particles using a w/o/w solvent evaporation technique. The lipase-containing PLGA/poly (vinyl alcohol) (PVA) nanoparticles were characterized with regard to morphology, size, size distribution, lipase-loading efficiency, in vitro lipase release, and stability of lipase activity. The size of nanoparticles increased as polymer concentration was increased. The size of particles was not significantly affected by the PVA concentration; on the other hand, the particle size distribution was the narrowest when 4% of PVA was used. In optimum conditions, we possessed nanoparticles that characterized 72.5% of encapsulation efficiency, $198.3{\pm}13.8 nm$ size diameter. During the initial burst phase, the in vitro release rate was very fast, reaching 83% within 12 days. Until days 6, enzyme activity increased as the amount of lipase released was increased.

Preparation and Characterization of Pamidronate-loaded PLGA Wafer for the Treatment of Bone Resorption (골 재흡수 치료를 위한 파미드로네이트를 함유한 이식형 생분해성 PLGA 웨이퍼의 제조와 특성결정)

  • 유제영;김상욱;강길선;성하수;정제교
    • Polymer(Korea)
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    • v.26 no.5
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    • pp.680-690
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    • 2002
  • Implantable biodegradable wafers were prepared with pamidronate -loaded poly (L-lactide-co-glycolide) (PLGA, 75 : 25 mole ratio by lactide to glycolide, molecular weight : 20000 and 90000 g/mole) by direct compression method for the sustained release of pamidronate to investigate the possibility for the treatment of bone resorption. Pamidronate-loaded PLGA powders were prepared by means of physical mixing and spray drying with the control of formulation factors and characterized by scanning electron microscope and X-ray diffractometer. The pamidronate-loaded PLGA powders fabricated into wafers by direct compression under the constant pressure and time at room temperature. These wafers were also observed for their structural characteristic, release pattern, and degradation pattern. The release rate of pamidronate increased with increasing their initial loading ratio as well as increasing wafer thickness. The molecular weight of PLGA affects the release pattern : the higher molecular weight of PLGA, the faster release rate. It can be explained that the higher viscosity of high molecular PLGA solution at same concentration tends to aggregate PLGA and pamidronate resulting in unstable pharmaceutical dosage form. This system had advantages in terms of simplicity in design and obviousness of drug release rate and nay be useful as an implantable dosage form for the treatment of aural cholesteatoma.

Electrospinning of PGA/PLA blends (PGA/PLA 블렌드의 전기방사)

  • You, Young;Park, Won-Ho;Min, Byung-Moo;Lee, Seung-Jin
    • Proceedings of the Korean Fiber Society Conference
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    • 2003.04a
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    • pp.380-381
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    • 2003
  • 지방족 폴리에스터계 고분자인 폴리락타이드 (polylactide, PLA), 폴리글리콜라이드 (polyglycolide, PCA)는 생체친화성이고 생분해성을 나타낸다. 그리고, 전기방사는 크게는 수 마이크로에서 작게는 수십 나노크기의 지름을 가지는 초극세 섬유인 나노섬유의 제조 기술로서 기존의 섬유 방사방식과는 근본적으로 다른 새로운 방사기술로 산업적인 응용 가능성이 무한한 미래지향적 기술로 최근 주목을 받고 있다. 본 연구에서는 이러한 우수한 생분해성과 생체적합성을 가진 PCA와 PLA 고분자를 블렌드 하여 부직포로 얻을 수 있는 전기방사를 이용하였다. (중략)

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Abnormal Behavior Monitoring System with YOLO AI Platform (YOLO 인공지능 플랫폼을 이용한 이상행동 감시 시스템)

  • Lee, Sang-Rak;Son, Byeong-Su;Park, Jun-Ho;Choi, Byeong-Yoon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2021.05a
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    • pp.431-433
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    • 2021
  • In this paper, abnormal behavior monitoring system using YOLO AI platform was implemented and had superior response characteristics compared to the conventional monitoring system using two-shot detection by using one-shot detection of YOLO system. The YOLO platform was trained using image dataset composed of abnormal behaviors such as assault, theft, and arson. The abnormal behavior monitoring system consists of client and server and can be applicable to smart cities to solve various crime problems if it is commercialized.

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Material Tests for the Evaluation of Safety Aspects for Recycled Plastic 'Tarai' as a Food Container (재활용플라스틱 다라이의 식품용기로서의 안전성 평가를 위한 재질 시험)

  • Lee, Keun-Taik;Lee, Jung-Pyo;Choi, Won-Sun;Woo, Moon-Jea;Lee, Jae-Rock
    • Journal of the Korea Organic Resources Recycling Association
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    • v.12 no.2
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    • pp.41-51
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    • 2004
  • Recycled plastic containers, so-called 'Tarai' in Korea which are often used as food containers, were collected from 23 domestic manufacturers. Then, their components were analyzed to find out whether they are safe for the use of food-contact material, to meet the standards and specifications of Korean hygienic regulations, the 'Food Code.' The components of the material were analyzed by using Fourier Transform-Infrared (FT-IR), Differential Scanning Calorimeter (DSC), and Elementary Analyzer (EA). The analysis of the FT-IR and the DSC showed that the main component of the samples was polyethylene. Furthermore, the analysis of the EA for 'Tarai' sample revealed the same ratio of C and H elements as in the case of polyethylene which was 1 to 2. Phenol and formaldehyde were not detected in all the samples. As for the antioxidant tests, Irganox 1010, Irganox 1076 and Irganox 1330 were detected in various samples. With regard to the material test for heavy metals, 7 out of 23 samples exceeded the limit value of 100 mg/kg in lead contents. No standard and specification is yet prescribed in the 'Food Code' for the material of 'Tarai' as plastic containers for food. This study suggests that the use of 'Tarai' as a food container should be strictly controlled.

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